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Total 741473 results found since Jan 2013.
Patient Controlled Subcutaneous Analgesia of Hydromorphone Versus Morphine to Treat Moderate and Severe Cancer Pain: A Randomized Double-Blind Controlled Trial
Hydromorphone and morphine are the common drugs used for the treatment of moderate to severe cancer pain. Patient controlled subcutaneous analgesia (PCSA) is an effective technique to manage cancer pain. However, few studies have been conducted to show the efficacy and safety of PCSA of hydromorphone for the relief of cancer pain.
Source: Journal of Pain and Symptom Management - September 22, 2023 Category: Palliative Care Authors: Xianzheng Zeng, Jiang Zhu, Jun Li, Chan Chen, Ling Sang, Maotong Liu, Li Song, Hui Liu Tags: Original Article Source Type: research
Behavior Problems Associated with Pain and Paresthesia
Pain is a subjective, aversive sensory and emotional experience and can cause or exacerbate problem behaviors. In this review, the biobehavioral model of pain is introduced and used to improve understanding by veterinarians of pain mechanisms and their relationship with problem behaviors. A range of potential indicators of discomfort are presented, illustrated by selected cases from the authors ’ behavior and pain referral clinics. Various myths exist around pain resulting in barriers to reporting assessment and treatment. Veterinarians should always consider discomfort in any case presenting with a problem behavior.
Source: Veterinary Clinics of North America: Small Animal Practice - September 22, 2023 Category: Veterinary Research Authors: Daniel S. Mills, Fergus M. Coutts, Kevin J. McPeake Source Type: research
“It saved me from the emergency department”: A qualitative study of patient experience of virtual urgent care in Ontario
ConclusionVirtual care options are valued by patients and families; however, the nature of care needed by those accessing VUC and who can best provide that care needs to be evaluated to position it for sustainability. Understanding how virtual care performs from both a provider and patient perspective during the current crisis has implications for designing alternative care options beyond the COVID-19 pandemic.
Source: PLoS One - September 22, 2023 Category: Biomedical Science Authors: Katie N. Dainty Source Type: research
International Urogynecology consultation chapter 2 committee 3: the clinical evaluation of pelvic organ prolapse including investigations into associated morbidity/pelvic floor dysfunction
ConclusionsThe clinical pelvic examination remains the central tool for evaluation of POP and a system such as the POP-Q or S-POP should be used to describe and quantify. The value of investigation for urinary tract dysfunction was discussed and findings presented. The routine addition of GI radiographic or physiological testing is currently not recommended. There are no data on the role of the routine assessment of pain or sexual function, and this area needs more study. Imaging studies alone cannot replace clinical examination for the assessment of POP.
Source: International Urogynecology Journal and Pelvic Floor Dysfunction - September 22, 2023 Category: OBGYN Source Type: research
The emerging role of the urinary microbiome in benign noninfectious urological conditions: an up-to-date systematic review
ConclusionThe study of the urogenital microbiome is rapidly expanding in urology. Noninfectious benign urogenital diseases, such as BPH, calcium oxalate stones, CPPS, and OAB were found to be associated with specific microbial taxonomies. Further research with larger study populations is necessary to solidify the knowledge of the urine microbiome in these conditions and to facilitate the creation of microbiome-based diagnostic and therapeutic approaches.
Source: World Journal of Urology - September 22, 2023 Category: Urology & Nephrology Source Type: research
The spino-parabrachio-amygdaloid pathway is critical for the manifestation of chronic pain
Neuropsychopharmacology, Published online: 22 September 2023; doi:10.1038/s41386-023-01745-7The spino-parabrachio-amygdaloid pathway is critical for the manifestation of chronic pain
Source: Neuropsychopharmacology - September 22, 2023 Category: Neurology Authors: Tyler S. Nelson Heather N. Allen Source Type: research
International Urogynecology consultation chapter 2 committee 3: the clinical evaluation of pelvic organ prolapse including investigations into associated morbidity/pelvic floor dysfunction
ConclusionsThe clinical pelvic examination remains the central tool for evaluation of POP and a system such as the POP-Q or S-POP should be used to describe and quantify. The value of investigation for urinary tract dysfunction was discussed and findings presented. The routine addition of GI radiographic or physiological testing is currently not recommended. There are no data on the role of the routine assessment of pain or sexual function, and this area needs more study. Imaging studies alone cannot replace clinical examination for the assessment of POP.
Source: International Urogynecology Journal - September 22, 2023 Category: OBGYN Source Type: research
Low back pain improvement after cervical laminoplasty in patients without tandem lumbar stenosis
ConclusionLBP improved after cervical laminoplasty in patients without lumbar stenosis.
Source: European Spine Journal - September 22, 2023 Category: Orthopaedics Source Type: research
Development and temporal validation of clinical prediction models for 1-year disability and pain after lumbar decompressive surgery. The Norwich Lumbar Surgery Predictor (development version)
ConclusionImportant PROM predictors are baseline PROMs, specific co-morbidities, work status, condition duration, previous lumbar operation, female, and smoking status. The ODI model predicted the likelihood of achieving a satisfactory state of both disability and pain.
Source: European Spine Journal - September 22, 2023 Category: Orthopaedics Source Type: research
Predictors of the masticatory muscle activity during chewing in patients with myogenous temporomandibular disorder
ConclusionsAccording to the present study, pain intensity, muscle and joint tenderness, and the severity of the disorder are predictive factors for MMA of the masseter and TA muscles in patients with mTMD. It is recommended that these parameters be considered when establishing clinical evaluation and treatment programs focusing on MMA in patients with mTMD.Clinical relevanceThe pain intensity, masticatory muscles and TMJ tenderness, and disorder severity are predictors for MMA of the masseter and TA in patients with mTMD. Pain intensity has the most significant importance.
Source: Clinical Oral Investigations - September 22, 2023 Category: Dentistry Source Type: research
A Prospective Study of Sensory Changes in Pediatric Patients After Minimally Invasive Repair of Pectus Excavatum With Cryoablation
This study sought to determine the frequency, onset, duration, and location of sensory changes and neuropathic pain after cryoablation.
Source: Journal of Pediatric Surgery - September 22, 2023 Category: Surgery Authors: R. Scott Eldredge, Krista Lai, Brielle Ochoa, Emily Khoury, Kristin Mihalcin, Daniel Ostlie, Justin Lee, Lisa McMahon, Craig Egan, Mark Molitor, Jae-O Bae, David Notrica, Benjamin E. Padilla Source Type: research
Unravelling a mysterious skin lesion in a patient with Ulcerative Colitis
A 53-year-old male with a history of long-standing ulcerative colitis presented to the emergency department with pain and swelling in his left lower extremity. He was diagnosed 12 years prior to the presentation with ulcerative colitis. He was initially managed with mesalamine for 5 years after which he lost response. For the following 6 years, he was placed on multiple immunosuppressive medications including adalimumab, infliximab, and mirikizumab. He remained symptomatic despite these medications.
Source: The American Journal of Medicine - September 22, 2023 Category: General Medicine Authors: Khaled Al-Smadi, Ammar Qureshi, Hasan Sqour, Ruijun Jeanna Su, Zeid Kayali Tags: Diagnostic Dilemma Source Type: research
Effect of Acupressure on Procedural Pain in Children: A Systematic Review
This study aims to systematically review the studies that evaluate the effectiveness of acupressure on minimally invasive procedural pain in children.
Source: Journal of PeriAnesthesia Nursing - September 22, 2023 Category: Nursing Authors: Tanju Ogul, Suzan Yildiz Tags: Review Source Type: research
Higher Buprenorphine Dose May Improve Treatment Retention for Opioid Use Disorder
Patients who received a higher daily dose of buprenorphine (24 mg) were significantly more likely to remain in treatment over six months compared with those who received a lower dose (16 mg), according to astudy published this week inJAMA Network Open.“The U.S. Food and Drug Administration recommends a target dose of 16 mg for buprenorphine maintenance treatment, with an upper limit of 24 mg,” wrote Laura Chambers, Ph.D., M.P.H., of Brown University and colleagues. The authors noted that this recommendation was established prior to the emerge nce of fentanyl in the illicit drug supply. “Some physicians have suggested...
Source: Psychiatr News - September 21, 2023 Category: Psychiatry Tags: buprenorphine discontinuation fentanyl JAMA Network Open Nora Volkow opioid use disorder Rhode Island treatment retention Source Type: research
Ultrasound Guided Erector Spinae Plane Block vs External Oblique Intercostal Plane Block for Nephrectomy
Condition: Post Operative Pain Interventions: Procedure: external oblique intercostal block; Procedure: Erector Spine block Sponsor: Menoufia University Recruiting
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials
