Number of Participants Diagnosed With Sarcoidosis by Bronchoscopic Transbronchial Needle Aspiration After COVID- 2019 .
Condition:   COVID -19 Associated Sarcoidosis Intervention:   Procedure: flexible bronchoscopy Sponsor:   Ain Shams University Completed
Source: ClinicalTrials.gov - September 21, 2023 Category: Research Source Type: clinical trials

Lytic Mastoid Lesion in a Patient with Otalgia
In this report, we present a patient with otalgia and an isolated lytic mastoid lesion.
Source: Head and Neck Pathology - September 21, 2023 Category: Pathology Source Type: research

Corticosteroid Use and Adherence in Patients Treated with Acthar Gel for Advanced Sarcoidosis
CONCLUSION: Acthar Gel is associated with reductions in corticosteroid use compared to alternatives. Better adherence is associated with greater reduction in corticosteroid exposure. Key Summary Points.PMID:37728695 | DOI:10.1007/s12325-023-02630-x
Source: Adv Data - September 20, 2023 Category: Epidemiology Authors: Kyle Hayes John Niewoehner J Bradford Rice Nathaniel Downes Ella Hagopian Izzy Ma George J Wan Source Type: research

The Reply
Sarcoidosis is a multisystemic disease of unknown cause. The diagnosis of sarcoidosis requires a compatible clinical picture accompanied by radiological and histopathological demonstration of the entity.1 Our patient did not present asthenia, usual symptoms, or extrapulmonary organ involvement.2 Laboratory tests did not identify hypercalcemia or angiotensin-converting enzyme elevation. On the other hand, the patient did not present typical radiological findings such as multiple micronodules with lymphatic distribution or lymphadenopathy; lung mass is a rare manifestation of the disease.
Source: The American Journal of Medicine - September 20, 2023 Category: General Medicine Authors: Francisco Le ón-Román, Beatriz Pintado-Cort Tags: Letter Source Type: research

Idiopathic Giant Cell Myocarditis: A Subtype of Granulomatous Myocarditis?
In the differential diagnosis of granulomatous myocarditis and sarcoidosis (including cardiac sarcoidosis),1 the authors made no allusion to the controversy about presence vs absence of granulomas in idiopathic giant cell myocarditis (IGCM).2
Source: The American Journal of Medicine - September 20, 2023 Category: General Medicine Authors: Oscar M.P. Jolobe Tags: Letter Source Type: research

Sarcoidosis or Crohn Disease: Diagnostic Dilemma
I read with great interest the Diagnostic Dilemma “Growing Pulmonary Nodule of Unknown Origin in a 61-Year-Old Woman” by Leon-Román et al.1 This clinical case has raised our awareness of sarcoidosis:
Source: The American Journal of Medicine - September 20, 2023 Category: General Medicine Authors: El ías Sánchez-Tejero Tags: Letter Source Type: research

Mysterious chronic skin lesions
A 10-year-old boy presented to our paediatric emergency department with a 10-month history of chronic diffuse cutaneous lesions including a recent lesion on the thumb (figure 1). The child was born in the Comoros, an East African island, and moved to Mayotte, a French East African island, at the age of 6 months with his family. He arrived in France in January 2022, and the lesions were first noted in February by his mother. He had three brothers who were well. His parents were not related, and he had not seen his father in a long time. His vaccinations were up to date. There was no other medical history of note and no simi...
Source: Archives of Disease in Childhood - Education and Practice - September 20, 2023 Category: Pediatrics Authors: Petat, H., Tedbirt, B., Zeggay, A., Michelet, I., Morin, C., Marguet, C. Tags: Epilogue Source Type: research

Is this the Dawning of AI for Sarcoidosis?
Source: Lung - September 20, 2023 Category: Respiratory Medicine Source Type: research

Current Applications of Artificial Intelligence in Sarcoidosis
ConclusionsMachine learning may be used to help diagnose pulmonary sarcoidosis and prognosticate in cardiac sarcoidosis. Deep learning is most comprehensively studied for diagnosis of pulmonary sarcoidosis and has less frequently been applied to prognostication in cardiac sarcoidosis. Radiomics has primarily been used to differentiate sarcoidosis from malignancy. To date, the use of AI in sarcoidosis is limited by the rarity of this disease, leading to small, suboptimal training sets. Nevertheless, there are applications of AI that have been used to study other systemic diseases, which may be adapted for use in sarcoidosis...
Source: Lung - September 20, 2023 Category: Respiratory Medicine Source Type: research

Using AI to generate Research Publications
Extremely helpful article. I've been doing this during Residency for a while now, mostly for case reports but also for two reviews so far. Just know, its not as simple as just saying "hey write me a review on sarcoidosis". It still takes human work, but once you get the work flow optimized, the effort-barrier for grinding out this type of work plummets. that is the biggest benefit IMO. Hope this helps!
Source: Student Doctor Network - September 18, 2023 Category: Universities & Medical Training Authors: SSerenity Tags: Medical Students (MD) Source Type: forums

Ocular sarcoidosis in adults and children: update on clinical manifestation and diagnosis
AbstractSarcoidosis-associated uveitis, is the predominant ocular sarcoidosis presentation, which affects both adults and children. For adults, international ocular sarcoidosis criteria (IWOS) and sarcoidosis-associated uveitis criteria (SUN) are defined. However, for children they are not yet established internationally. Due to the specificity of pediatric manifestations of sarcoidosis, this task is even more challenging. In children, sarcoidosis is subdivided into Blau syndrome and early-onset sarcoidosis (BS/EOS) affecting younger children (<  5 years) and the one affecting older children with clinical presentatio...
Source: Journal of Ophthalmic Inflammation and Infection - September 18, 2023 Category: Opthalmology Source Type: research

Viruses, Vol. 15, Pages 1942: CRISPR/Cas9-Mediated Targeting of BPV-1-Transformed Primary Equine Sarcoid Fibroblasts
rg Kerstin Hahn Equine sarcoids (EqS) are fibroblast-derived skin tumors associated with bovine papillomavirus 1 and 2 (BPV-1 and -2). Based on Southern blotting, the BPV-1 genome was not found to be integrated in the host cell genome, suggesting that EqS pathogenesis does not result from insertional mutagenesis. Hence, CRISPR/Cas9 implies an interesting tool for selectively targeting BPV-1 episomes or genetically anchored suspected host factors. To address this in a proof-of-concept study, we confirmed the exclusive episomal persistence of BPV-1 in EqS using targeted locus amplification (TLA). To investigate the CRI...
Source: Viruses - September 17, 2023 Category: Virology Authors: Anne Monod Christoph Koch Christoph Jindra Maarten Haspeslagh Denise Howald Christian Wenker Vinzenz Gerber Sven Rottenberg Kerstin Hahn Tags: Article Source Type: research

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