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Total 11811 results found since Jan 2013.

The initial intracranial pressure spike phenomenon
DiscussionOur results highlight an intracranial opening pressure ‘spike’ phenomenon. This spike was 15.2 mmHg higher than the plateau, which is reached at 20 min after insertion. Several possible causes exist which require further research in larger cohorts, including sedation and pain response. Regardless of causation, this study provides key information on the use of ICP monitoring devices, guiding interpretation and when to obtain measurements.
Source: Acta Neurochirurgica - September 11, 2023 Category: Neurosurgery Source Type: research

Abdominal pseudocyst complicating ventriculoperitoneal shunt: A rare indication for ventriculopleural shunt conversion
Significant enlargement of the lateral ventricles in the patient with congenital hydrocephalus. Key Clinical MessageAbdominal pseudocyst is a rare complication of ventriculoperitoneal (VP) shunt placement. Ventriculopleural shunt (VPL) can be an effective treatment option for the recurrent complications of VP shunt failure.AbstractAbdominal pseudocyst (APC) is a rare complication of ventriculoperitoneal (VP) shunt placement for the treatment of congenital hydrocephalus. This case report presents a two-and-a-half-year-old male child who underwent VP shunt placement for aqueductal stenosis-related hydrocephalus. The patient ...
Source: Clinical Case Reports - September 8, 2023 Category: General Medicine Authors: Nishan Shrestha, Naveen Gautam, Merina Shrestha Tags: CASE REPORT Source Type: research

Minimally invasive third ventriculostomy with stereotactic internal shunt placement for the treatment of tumor-associated noncommunicating hydrocephalus
ConclusionssTVIP led to a significant symptom control and was associated with low operative morbidity, along with a high rate of ventriculoperitoneal shunt independency during the follow-up period. Therefore, sTVIP constitutes a highly effective and minimally invasive treatment option for tumor-associated obstructive hydrocephalus, even in cases with a narrow prepontine interval.
Source: Acta Neurochirurgica - September 7, 2023 Category: Neurosurgery Source Type: research

Newly identified adverse events of enzalutamide using the food and drug administration adverse event reporting system
CONCLUSION: Our study revealed novel adverse events associated with enzalutamide, particularly in the nervous system, that have not been previously documented. These findings have important implications for future clinical medication guidelines.PMID:37670490 | DOI:10.1080/14740338.2023.2255524
Source: Expert Opinion on Drug Safety - September 6, 2023 Category: Drugs & Pharmacology Authors: Xin Wang Lina Chang Zhenhua Li Yuanfang Jiang Yue Chen Xinli Jia Qiye Wang Xiaolu Ren Zhifang Ma Wei Zhang Source Type: research

Correction: High homocysteine is associated with idiopathic normal pressure hydrocephalus in deep perforating arteriopathy: a cross-sectional study
Source: BMC Geriatrics - September 6, 2023 Category: Geriatrics Authors: Shisheng Ye, Kaiyan Feng, Yizhong Li, Sanxin Liu, Qiaoling Wu, Jinwen Feng, Xiaorong Liao, Chunmei Jiang, Bo Liang, Li Yuan, Hai Chen, Jinbo Huang, Zhi Yang, Zhengqi Lu and Hao Li Tags: Correction Source Type: research

Assessing white matter microstructural changes in idiopathic normal pressure hydrocephalus using voxel-based R2* relaxometry analysis
ConclusionOur analysis highlights the microstructural changes without iron deposition in the SLF and SS, and their association with cognitive impairment and gait disturbance in patients with iNPH.
Source: Frontiers in Neurology - September 5, 2023 Category: Neurology Source Type: research

The incidence and risk factors of unplanned reoperation in endoscopic endonasal surgeries: a single center study
AbstractThe incidence of unplanned reoperation after surgery during the same hospitalization is considered one of most important evaluation indicators for health care quality. The purpose of this study was to determine the incidence and risk factors related to unplanned reoperation after an endoscopic endonasal approach (EEA). All patients who underwent elective endoscopic endonasal surgery from January 2016 to December 2021 in the Department of Neurosurgery, Tangdu Hospital, Air Force Military Medical University, were included. We identified the patients who underwent an unplanned reoperation and those who did not and div...
Source: Neurosurgical Review - September 4, 2023 Category: Neurosurgery Source Type: research

Multidirectional Nystagmus as the Presenting Sign of Brain Tumor with Hydrocephalus
Neuropediatrics DOI: 10.1055/s-0043-1772462 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text
Source: Neuropediatrics - September 4, 2023 Category: Neurology Authors: Bellini, Tommaso Siri, Laura De Grandis, Elisa Formigoni, Clelia Tortora, Domenico Piccotti, Emanuela Tags: Videos and Images in Neuropediatrics Source Type: research

The clinical course and outcomes of non-aneurysmal subarachnoid hemorrhages in a single-center retrospective study
ConclusionsNon-aneurysmal SAH seems to have a good prognosis for majority of patients, especially for patients with a PSAH. Non-aneurysmal SAH patients are however affected by vasospasm and hydrocephalus and have similar risk factors for poor outcome as patients with aneurysmal SAH. This suggests that it is the severity of the bleed rather than the etiology that associates with poor outcome.
Source: Acta Neurochirurgica - September 2, 2023 Category: Neurosurgery Source Type: research

Imaging features to distinguish posterior fossa ependymoma subgroups
ConclusionMorphological characteristics from imaging differ between posterior fossa ependymoma subtypes and may help to distinguish them preoperatively.Clinical relevance statementThis study provides a tool to differentiate between group A and group B ependymomas, which will ultimately allow the therapeutic strategy to be adapted in the early stages of patient management.Key Points•Posterior fossa ependymoma subtypes often have different imaging characteristics.•Posterior fossa ependymomas group A are commonly median or lateral tissular calcified masses, with incomplete enhancement, affecting young children and respons...
Source: European Radiology - September 2, 2023 Category: Radiology Source Type: research

The clinical course and outcomes of non-aneurysmal subarachnoid hemorrhages in a single-center retrospective study
ConclusionsNon-aneurysmal SAH seems to have a good prognosis for majority of patients, especially for patients with a PSAH. Non-aneurysmal SAH patients are however affected by vasospasm and hydrocephalus and have similar risk factors for poor outcome as patients with aneurysmal SAH. This suggests that it is the severity of the bleed rather than the etiology that associates with poor outcome.
Source: Acta Neurochirurgica - September 2, 2023 Category: Neurosurgery Source Type: research

Minocycline attenuates hydrocephalus and inhibits iron accumulation, ependymal damage and epiplexus cell activation after intraventricular hemorrhage in aged rats
Exp Neurol. 2023 Aug 29:114523. doi: 10.1016/j.expneurol.2023.114523. Online ahead of print.ABSTRACTIntracerebral hemorrhage is primarily a disease of the elderly and it is frequently accompanied by intraventricular hemorrhage (IVH) which can lead to posthemorrhagic hydrocephalus and poor prognosis. Red blood cell iron has been implicated in brain injury after cerebral hemorrhage. The current study examined using T2* magnetic resonance imaging (MRI) to detect periventricular iron deposition after IVH and investigated the effects of minocycline on hydrocephalus in an aged rat IVH model. It had three parts. In part 1, male a...
Source: Experimental Neurology - August 31, 2023 Category: Neurology Authors: Yingfeng Wan Katherine G Holste Fenghui Ye Ya Hua Richard F Keep Guohua Xi Source Type: research