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Effect of Initial Treatment With a Single Pill Containing Quadruple Combination of Quarter Doses of Blood Pressure Medicines Versus Standard Dose Monotherapy in Patients With Hypertension on Ambulatory Blood Pressure Indices: Results From the QUARTET Study
Circulation. 2023 Jul 25;148(4):375-377. doi: 10.1161/CIRCULATIONAHA.123.064964. Epub 2023 Jul 24.NO ABSTRACTPMID:37486996 | DOI:10.1161/CIRCULATIONAHA.123.064964
Source: Circulation - July 24, 2023 Category: Cardiology Authors: Janis M Nolde Emily Atkins Simone Marschner Graham S Hillis John Chalmers Laurent Billot Mark R Nelson Christopher M Reid Peter Hay Michael Burke Shirley Jansen Tim Usherwood Anthony Rodgers Clara K Chow Markus P Schlaich Source Type: research
The Kid LAROI Performs Surprise Set at Hotel Bar After Malaysia Music Festival Is Canceled
The Kid LAROI didn’t let fans down when Malaysia’s Good Vibes Festival — which he was scheduled to headline Saturday (July 22) — was unexpectedly called off. The fest’s sudden cancelation came after The 1975’s set on Friday, when frontman Matty Healy slammed the country’s restrictive LGBTQ laws as…#malaysia #mattyhealy #rossmacdonald #goodvibes #malaysian #kualalumpur #thousandmiles #withoutyouanddiva #instagramstories #laroi
Source: Reuters: Health - July 23, 2023 Category: Consumer Health News Source Type: news
New Commanders owner Josh Harris ' focused on changing the culture '
LANDOVER, Md. – For Josh Harris, the Washington Commanders are not just the team he grew up rooting for as a kid from Chevy Chase, Maryland. The organization runs through his DNA. “This franchise is part of who I am,” Harris said, “and who I became.” Harris – owner of the NHL’s New Jersey Devils…#landover #joshharris #washingtoncommanders #chevychase #maryland #newjerseydevils #nba #philadelphia76ers #commanders #dansnyder
Source: Reuters: Health - July 21, 2023 Category: Consumer Health News Source Type: news
Your workplace wants you to swallow a happy pill. What if you found collective joy instead?
For years the corporate diktat has been that happiness must be achieved alone, but many are turning to communities for joyThere are 11-year-olds with dyed blue hair, ripped men in their 40s and dirtbag hipsters in their 20s, all hanging from plastic crimps on the walls of a high-ceilinged gym. As electronic dance music plays loudly, Gatorade and microbrews are being served to the audience. They dance and clap in unison. Some gather to chat and cheer at those climbing the walls around them. It ’s exuberant, anarchic, and although I am not a climber, I am in the middle of it, sitting cross-legged on the sweaty floor.I ’m...
Source: Guardian Unlimited Science - July 20, 2023 Category: Science Authors: Alissa Quart Tags: Life and style Communities Society Psychology Source Type: news
Families with infants and toddlers in the COVID-19 pandemic: parental stress and child development considering social class
DISCUSSION: In order to mitigate the psychosocial consequences of the COVID-19 pandemic for families and to improve children's chances of growing up in a healthy way that promotes their development, it is necessary to support families in need without stigmatization.PMID:37470841 | PMC:PMC10371926 | DOI:10.1007/s00103-023-03744-x
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - July 20, 2023 Category: International Medicine & Public Health Authors: Ilona Renner Susanne M Ulrich Anna Neumann Digo Chakraverty Source Type: research
The SUMO-NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure
Nat Struct Mol Biol. 2023 Jul 20. doi: 10.1038/s41594-023-01045-0. Online ahead of print.ABSTRACTSUMOylation regulates numerous cellular processes, but what represents the essential functions of this protein modification remains unclear. To address this, we performed genome-scale CRISPR-Cas9-based screens, revealing that the BLM-TOP3A-RMI1-RMI2 (BTRR)-PICH pathway, which resolves ultrafine anaphase DNA bridges (UFBs) arising from catenated DNA structures, and the poorly characterized protein NIP45/NFATC2IP become indispensable for cell proliferation when SUMOylation is inhibited. We demonstrate that NIP45 and SUMOylation o...
Source: Mol Biol Cell - July 20, 2023 Category: Molecular Biology Authors: Emil P T Hertz Ignacio Alonso-de Vega Thomas Kruse Yiqing Wang Ivo A Hendriks Anna H Bizard Ania Eugui-Anta Ronald T Hay Michael L Nielsen Jakob Nilsson Ian D Hickson Niels Mailand Source Type: research
Families with infants and toddlers in the COVID-19 pandemic: parental stress and child development considering social class
DISCUSSION: In order to mitigate the psychosocial consequences of the COVID-19 pandemic for families and to improve children's chances of growing up in a healthy way that promotes their development, it is necessary to support families in need without stigmatization.PMID:37470841 | PMC:PMC10371926 | DOI:10.1007/s00103-023-03744-x
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - July 20, 2023 Category: International Medicine & Public Health Authors: Ilona Renner Susanne M Ulrich Anna Neumann Digo Chakraverty Source Type: research
