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Total 478012 results found since Jan 2013.

The anxiolytic-like effect of an essential oil derived from Spiranthera odoratissima A. St. Hil. leaves and its major component, β-caryophyllene, in male mice
In conclusion, these results suggest that the essential oil derived from S. odoratissima produces an anxiolytic-like effect without altering motor performance and that this effect is mediated by 5-HT1A but not via benzodiazepine receptors. In addition, the major component, β-caryophyllene, also has an anxiolytic-like effect that may contribute to the effects of EO, but this effect does not seem to be mediated via 5-HT1A or benzodiazepine receptors. Graphical abstract Highlights ► S. odoratissima essential oil (EO) and β-caryophyllene has anxiolytic-like effect. ► EO or β-caryophyllene does not produce motor impai...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - November 21, 2014 Category: Psychiatry Source Type: research

Teaching the Teachers of Clinical Psychopharmacology.
Authors: Salzman C, Glick ID Abstract This commentary focuses on psychopharmacology teachers and their teaching. The authors offer broadly based pedagogic suggestions on how to deliver evidence-based and neurobiologically informed prescribing information to clinicians at all levels of experience. They argue that teaching essential psychopharmacology knowledge and practice must be up-to-date, accurate, and consistent with the reality of an individual patient's life experience and beliefs. They stress that educators must teach that nonpsychopharmacological factors in a patient's life may be as relevant to the treatme...
Source: The Journal of American Association of Directors of Psychiatric Residency Training - December 6, 2014 Category: Psychiatry Tags: Acad Psychiatry Source Type: research

Teaching the Teachers of Clinical Psychopharmacology
Abstract This commentary focuses on psychopharmacology teachers and their teaching. The authors offer broadly based pedagogic suggestions on how to deliver evidence-based and neurobiologically informed prescribing information to clinicians at all levels of experience. They argue that teaching essential psychopharmacology knowledge and practice must be up-to-date, accurate, and consistent with the reality of an individual patient’s life experience and beliefs. They stress that educators must teach that nonpsychopharmacological factors in a patient’s life may be as relevant to the treatment setting as the actual...
Source: Acadademic Psychiatry - December 4, 2014 Category: Psychiatry Source Type: research

Essential Psychopathology & Its Treatment, 4th Ed.
Although this 720-page textbook does not make for light reading, it does come in handy as a reference on mental disorders. In Essential Psychopathology and Its Treatment, Mark D. Kilgus, Jerrold S. Maxmen, and Nicholas G. Ward step back from a strictly theoretical approach and toward scientific evidence with clearer standards for data-driven treatment. The book offers new evidence without throwing away what is already known — the authors kept what works and added new discoveries. They place clinical information in historical context so that newer clinicians can understand how the field has evolved, and create a ki...
Source: Psych Central - January 3, 2016 Category: Psychiatry Authors: Tina Arnoldi Tags: Book Reviews Disorders Dual Diagnosis General Professional Psychological Assessment Psychology Psychotherapy Treatment books for clinicians books for therapists books on psychopathology diagnosing mental disorders Dsm essential Source Type: news

Quetiapine-induced Bradycardia and Hypotension in the Elderly—A Case Report
Conclusion We suggest that clinicians remain vigilent for signs or symptoms of adverse effects in their elderly patients who take SGAs. Elderly patients with histories of heart failure, myocardial infarction, and/or conduction abnormalities may be particularly vulnerable to cardiac abnormalities while on quetiapine, particularly at higher dosages, and thus should be continually and closely monitored for any symptoms of cardiac distress. References 1. Gareri P, De Fazio P, De Fazio S, et al. Adverse effects of atypical antipsychotics in the elderly: a review. Drugs Aging. 2006;23:937–956. 2. Nielsen J, Graff C, Kanters JK...
Source: Innovations in Clinical Neuroscience - February 10, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Behavioral and Cognitive Neurology Case Report Current Issue Dementia Medical Issues Neurodegenerative Disease Psychopharmacology Substance Use Disorders bradycardia hypotension quetiapine second generation antipsychotic Source Type: research

Common Factors in Pediatric Psychiatry: A Review of Essential and Adjunctive Mechanisms of Treatment Outcome
Journal of Child and Adolescent Psychopharmacology , Vol. 0, No. 0.
Source: Journal of Child and Adolescent Psychopharmacology - April 28, 2016 Category: Pediatrics Authors: Alessandro S. De NadaiMarc S. KarverTanya K. MurphyMark A. CavittJeffrey L. AlvaroMichael BengtsonSaundra StockAndrew C. RakhshaniEric A. Storch Source Type: research

Neuroprotective effect of the group III mGlu receptor agonist ACPT-I after ischemic stroke in rats with essential hypertension
In conclusion, the current findings provide further evidence for the neuroprotective effects of ACPT-I against ischemic damage. These findings may have clinical implications because hypertension is an important risk factor for ischemic stroke.
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - February 21, 2018 Category: Psychiatry Source Type: research

Psychopharmacology Problem Solving: Principles & Practices to Get It Right
A longstanding debate in the field of psychology is whether or not psychologists — specifically, PhDs and PsyDs who serve in a clinical capacity — should, like psychiatrists (who have MDs), be able to prescribe medication. At present, two states permit prescriptive authority for appropriately trained psychologists: New Mexico and Louisiana, with more states on the horizon for approval. That authority is monitored under the supervision of a psychiatrist or other qualified practicing medical physician. Meanwhile, the American Psychological Association (APA), while it supports prescriptive authority for clinical psych...
Source: Psych Central - December 24, 2014 Category: Psychiatry Authors: K.M. McCann, PhD Tags: Book Reviews Disorders General Medications Professional Psychiatry Psychology Treatment Pharmacology Psychiatric Medication Psychopharmacology Scott Kraly Source Type: news

Practical Clinical Trials in Psychopharmacology: A Systematic Review
Abstract: Practical clinical trials (PCTs) are randomized experiments under typical practice conditions with the aim of testing the “real-life” benefits and risks of therapeutic interventions. Influential PCTs have been conducted in cardiology, oncology, and internal medicine. Psychotropic medications are widely and increasingly used in medical practice. This review examines recent progress in conducting PCTs in psychopharmacology. The January 2000 to October 2014 MEDLINE, Scopus, and ClinicalTrials.gov databases were searched for peer-reviewed publications of PCTs with at least 100 subjects per treatment arm. Most PCT...
Source: Journal of Clinical Psychopharmacology - March 3, 2015 Category: Psychiatry Tags: Review Article Source Type: research

Toward a new predoctoral model: Education and training in clinical psychopharmacology.
A ubiquitous research finding in regional and national studies is that at least 40% of persons with mental disorders cannot access mental health services, and pharmacotherapy in particular. The American Psychological Association’s (APA) designated programs for the provision of education and training in clinical psychopharmacology can be of great help in alleviating this national need. We address key developments relevant to the foundation of a predoctoral model of clinical psychopharmacology education and training. To this end, an overview of the Master of Science in Clinical Psychopharmacology (MSCP) program at The Chic...
Source: Experimental and Clinical Psychopharmacology - September 30, 2021 Category: Psychiatry & Psychology Source Type: research

Psychopharmacology of attention: The impact of drugs in an age of increased distractions.
This Special Issue, Psychopharmacology of Attention: The Impact of Drugs in an Age of Increased Distractions, not only provides novel data on the relationships among attention, alcohol use, and other drug use, but also offers new insights that could inform development of potential pharmacotherapies for ADHD. The first three articles quantify effects of frequently prescribed psychostimulants in male rodents on two components of ADHD: diminished impulse control and inappropriate sensory signal processing. This Special Issue shifts to the clinical study of ADHD in the next two articles, both of which provide important caveats...
Source: Experimental and Clinical Psychopharmacology - October 7, 2013 Category: Psychiatry & Psychology Authors: Liguori, Anthony Source Type: research

Unmet needs in paediatric psychopharmacology: present scenario and future perspectives
Paediatric psychopharmacology holds great promise in two equally important areas of enormous biomedical and social impact, namely the treatment of behavioural abnormalities in children and adolescents, and the prevention of psychiatric disorders with adolescent- or adult-onset. Yet, in striking contrast, pharmacological treatment options presently available in child and adolescent psychiatry are dramatically limited. The most important currently unmet needs in paediatric psychopharmacology are: the frequent off-label prescription of medications to children and adolescents based exclusively on data from randomized controlle...
Source: European Neuropsychopharmacology - June 20, 2015 Category: Psychiatry & Psychology Authors: Antonio M. Persico, Celso Arango, Jan K. Buitelaar, Christoph U. Correll, Jeffrey C. Glennon, Pieter J. Hoekstra, Carmen Moreno, Benedetto Vitiello, Jacob Vorstman, Alessandro Zuddas, the European Child and Adolescent Clinical Psychopharmacology Network Tags: REVIEW Source Type: research

Rapid opiate detoxification and antagonist induction under general anaesthesia or intravenous sedation is humane, sometimes essential and should always be an option. Three illustrative case reports involving diabetes and epilepsy and a review of the literature
When abstinence is an appropriate goal, controlled studies and systematic reviews confirm that rapid, antagonist-precipitated opiate withdrawal procedures are the most effective and cost effective methods of initiating abstinence, and naltrexone (NTX) maintenance. While ‘rapid’ withdrawal, better conceptualised as Rapid Antagonist Induction (RAI), can often be humanely achieved with modest sedation levels, we present three case histories to support our argument that for some patients, general anaesthesia (GA), or techniques of intravenous sedation (IVS) that approach GA, are essential for safety and success. Th...
Source: Journal of Psychopharmacology - January 7, 2014 Category: Psychiatry Authors: Brewer, C., de Jong, C., Williams, J. Tags: Short Reports Source Type: research

Measles vaccination essential: Hamburg's outgoing words
Margaret A. Hamburg, M.D., outgoing commissioner of the Food and Drug Administration, had some strong final words for American consumers: if you or your children have not been vaccinated (or had measles), vaccination now is essential.
Source: The Brown University Child and Adolescent Psychopharmacology Update - February 23, 2015 Category: Psychiatry Tags: From the FDA Source Type: research

An update on Experimental and Clinical Psychopharmacology: Something old, something new, something borrowed, something green?
In this editorial, the author provides an update on Experimental and Clinical Psychopharmacology in several areas. First, the journal will continue to accept original research reports and full reviews as it has in past years. The author hopes to still receive outstanding manuscripts in the journal's primary areas of strength, such as clinical research on alcohol use and cigarette smoking. The journal will also continue to publish an annual special issue on a current topic in the field. Second, the journal now accepts brief communications, brief reviews, and case reports. The authors sees these new formats as opportunities ...
Source: Experimental and Clinical Psychopharmacology - February 1, 2018 Category: Psychiatry & Psychology Source Type: research