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The (sort of, partial) Father mRNA Vaccines Who Now Spreads Vaccine Misinformation (Part 1)
By DAVID WARMFLASH, MD Robert W. Malone, MD MS, is a physician-scientist who will live in infamy, thanks to the Joe Rogan Experience Podcast boosting his visibility this past December regarding his criticism of COVID-19 vaccines, particularly the mRNA vaccines (Moderna and Pfizer-BioNTech). Subsequently, Malone was banned from Twitter, which further boosted his celebrity status. Describing himself as the inventor of mRNA vaccine technology, he has been reaching a growing number of people with a narrative that makes COVID-19 vaccination sound scary. We cannot embed clips from the Rogan interview, which lasted about three...
Source: The Health Care Blog - March 17, 2022 Category: Consumer Health News Authors: matthew holt Tags: COVID-19 Health Policy antivaxxer COVID-19 vaccine David Warmflash Joe Rogan Robert Malone Source Type: blogs

Fight Aging! Newsletter, December 27th 2021
We report that whereas microglia are characterized by marked gene-level alterations related to negative regulation of protein phosphorylation and phagocytic vesicles, astrocytes show activation of enzyme- or peptidase-inhibitor signaling after detectable changes in BBB permeability. We also identify several genes enriched in these pathways that are notably altered after BBB breakdown. Our data reveal that microglia and astrocytes play an active role in maintaining BBB stabilization and corralling infiltrating cells, and thus might potentially function in ameliorating the lesions and neurologic disabilities in CNS diseases....
Source: Fight Aging! - December 26, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, November 8th 2021
In conclusion, in less common and visible cardiovascular diseases, it is crucial to recognize substantial progress and achievement, given that penetration of such information into clinical practice and the patient community can be inconsistent. Diseases such as hypertrophic cardiomyopathy, pulmonary arterial hypertension, and ATTR cardiac amyloidosis, once linked to a uniformly adverse prognosis, are now associated with the opportunity for patients to experience satisfactory quality of life and extended longevity. VitaDAO, a Novel Approach to Crowdfunding Life Science Research https://www.fightaging.org/archive...
Source: Fight Aging! - November 7, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Digital Health Interests Of Pharma Giants Boehringer Ingelheim, Takeda, Astrazeneca, Amgen And Roche
With their extending reaches, resources and influence, pharmaceutical heavyweights have the potential to shape the digital health landscape to line up with their interests. And to have a better picture of where those interests lie, it is worth taking a look at what moves pharma giants are making in this sphere. With this in mind, we started a series of articles focusing on the digital health efforts of 14 global pharma companies.  The first article explored developments coming from Johnson & Johnson, Pfizer, Bayer and Novartis, while the second article investigated those coming from Merck, GlaxoSmithKline, AbbV...
Source: The Medical Futurist - November 4, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: TMF Artificial Intelligence in Medicine Digital Health Research Future of Pharma sleep patient empowerment pharmaceutics roche MySugr Astra-Zeneca DTx takeda Boehringer Ingelheim Amgen digitisation Quire.ai Renalytix Eko Source Type: blogs

How to Plan and Carry Out a Simple Self-Experiment, a Single Person Trial of Khavinson Peptides for Thymic Regrowth
The objective here is to produce doses of the peptides dissolved in 0.5 ml of phosphate buffered saline in sealed vials, ready to be used with the injection system, with as little contamination as possible from the environment, and stored a freezer until it is ready to use. Depending on the size of the vial, it might be able to contain doses for multiple injections, but it is better to stick to one dose per vial. Peptides are sensitive to free-thaw cycles, so you want as few of those as possible. When ordering epitalon, thymogen, and vilon, they will arrive as lyophilized (freeze-dried) crystals or powder. Thymogen ...
Source: Fight Aging! - November 1, 2021 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs

Food Intolerances: A Warning of Bad Things Ahead
I’ve recently discussed how the majority of food intolerances, whether to FODMAPs, histamine, nightshades, fructose, etc., are really manifestations of dysbiosis and SIBO. Here is another way to view these phenomena: Food intolerances are your body’s signal to you that serious deterioration in your health is coming. In other words, if all you do is choose to reduce or eliminate the offending food, you are still left with the massive disruption of your intestinal microbiome that caused the food intolerance in the first place, along with increased intestinal permeability and endotoxemia. So say you eliminate ferm...
Source: Wheat Belly Blog - November 1, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open microbiota prebiotic probiotic sibo small intestinal bacterial super gut undoctored wheat belly Source Type: blogs

Gastroenterology Embraces Artificial Intelligence
AI and machine learning have the potential to redefine the management of several GI disorders.John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article.Colonoscopy is one of the true success stories in modern medicine.Studies have demonstrated that colonoscopy screening detects the cancer at a much earlier stage, reducing the risk of invasive tumors and metastatic disease, andreducing mortality. However, while colorectal cancer is highly preventable, it is thethird leading cause of cancer-related deathsin the U.S. A...
Source: Life as a Healthcare CIO - October 13, 2021 Category: Information Technology Source Type: blogs

Fight Aging! Newsletter, October 4th 2021
In conclusion, premature thymic involution and chronic inflammation greatly contribute to increased morbidity and mortality in CKD patients. Mechanisms are likely to be multiple and interlinked. Even when the quest to fountain of youth is a pipe dream, there are many scientific opportunities to prevent or to, at least in part, reverse CKD-related immune senescence. Further studies should precisely define most important pathways driving premature immune ageing in CKD patients and best therapeutic options to control them. Extending Life Without Extending Health: Vast Effort Directed to the Wrong Goals https://www...
Source: Fight Aging! - October 3, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Man With Sudden Onset of Gastroparesis
By HANS DUVEFELT Leo Dufour is not a diabetic. He is in his mid 50s, a light smoker with hypertension and a known hiatal hernia. He has had occasional heartburn and has taken famotidine for a few years along with his blood pressure and cholesterol pills. Over the past few months, he started to experience a lot more heartburn, belching and bloating. Adding pantoprazole did nothing for him. I referred him to a local surgeon who did an upper endoscopy. This did not reveal much, except some retained food in his stomach. A gastric emptying study showed severe gastroparesis. The surgeon offered him a trial of metoclopra...
Source: The Health Care Blog - September 16, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Primary Care Hans Duvefelt Source Type: blogs

The 9 Trends Shaping the Future of Pharma
The drug sends a message to a caregiver after the patient swallowed it. The doctor prescribes virtual reality treatments for migraines. Do you think it is science fiction? You are mistaken. Just let me familiarize you with the top 10 trends shaping the future of pharma. And if you want to have a more in-depth analysis of the topic, read our related ebook, Technologies Shaping the Future of Pharma! Technologies Shaping the Future of Pharma We designed this e-book to serve as a collection of relevant examples, best practices and exciting ideas that can help any pha...
Source: The Medical Futurist - August 26, 2021 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine Future of Pharma 3d printing artificial intelligence augmented reality digital health Innovation nanotechnology Personalized medicine pharmacology virtual reality VR gc4 pharmacies pharmacogenetics Source Type: blogs

The 10 Trends Shaping the Future of Pharma
The drug sends a message to a caregiver after the patient swallowed it. The doctor prescribes virtual reality treatments for migraines. Do you think it is science fiction? You are mistaken. The pharma industry has taken a big swung into digital transformation. All participants invest in digital health topics. But as with all trending issues, and there is a lot of fuss that is hard to see through. As the medical community increasingly acknowledges the importance of digital health, the cultural shift we so often talk about is still a way to go. To change that, the first step is always getting to know what’s coming. ...
Source: The Medical Futurist - August 26, 2021 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine Future of Pharma 3d printing artificial intelligence augmented reality digital health Innovation nanotechnology Personalized medicine pharmacology virtual reality VR gc4 pharmacies pharmacogenetics Source Type: blogs

Fight Aging! Newsletter, August 23rd 2021
In this study, we used the UK Biobank (n = 440,185) to resolve previous ambiguities in the relationship between serum IGF-1 levels and clinical disease. We examined prospective associations of serum IGF-1 with mortality, dementia, vascular disease, diabetes, osteoporosis, and cancer, finding two generalized patterns. First, IGF-1 interacts with age to modify risk in a manner consistent with antagonistic pleiotropy; younger individuals with high IGF-1 are protected from disease, while older individuals with high IGF-1 are at increased risk for incident disease or death. Second, the association between IGF-1 and risk ...
Source: Fight Aging! - August 22, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Strength Training and Aerobic Exercise Reduce Cancer Mortality
Researchers here note that undertaking strength training and aerobic exercise acts to reduce mortality due to cancer, to a similar degree as these activities are known to reduce all cause mortality in later life. The mechanisms involved are likely diverse, but it is worth noting that (a) muscle tissue is metabolically active in beneficial ways, such that more muscle is better than less muscle, (b) better immune function is linked to exercise, and immune surveillance is critical to cancer prevention, and (c) exercise helps to reduce chronic inflammation, where chronic inflammation helps to drive the establishment and develo...
Source: Fight Aging! - August 17, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How Spiritfarer Helped Me Through the Pandemic
by Matthew Tyler (@PalliDad)During what can only be described as a challenging year, I found Thunderlotus ’s gameSpiritfarer just in the nick of time. In this “cozy management game about dying,” you assume the role of a young woman named Stella who is charged with shuttling spirits to the gates of the afterlife. Unexpectedly,Spiritfarer served as both an escape from and means of processing my experience as a healthcare worker during the pandemic.From top to bottom,Spiritfarer exudes tranquility. The animations are bright and vibrant, and the music is soothing yet melancholy, invoking nostalgia for younger innocent da...
Source: Pallimed: A Hospice and Palliative Medicine Blog - July 14, 2021 Category: Palliative Care Tags: covid grief palliative care pandemic Tyler video games Source Type: blogs

100 Honesty Quotes to Help You Improve Your Self-Esteem and Happiness
Honesty. Such an important but sometimes tough thing to stay true to. It’s often easier to just tell a white or perhaps even darker lie. To skirt around how you really think and feel. But even though it might be tough there is also so much to be gained from being more honest both with yourself and the people in your life: The more honest you can be with yourself the easier it will be to be who you deep down want to be but also to improve aspects of your life that are truly in need of that. The more honest you are with both yourself and others the more your self-respect, your relationships and your confidence in yourself...
Source: Practical Happiness and Awesomeness Advice That Works | The Positivity Blog - May 10, 2021 Category: Consumer Health News Authors: Henrik Edberg Tags: Personal Development Source Type: blogs