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Total 484 results found since Jan 2013.

Underfunding Research Of Female Health Leaves Huge Amounts Of Money On The Table
“Did you know that at least one-third of women have lower back pain before their periods every month, and yet, nobody seems to fully understand why?” – asked a Medical Futurist team member a little while ago. The question led to a discussion about the differences in research, funding and understanding of male-only and female-only health issues, and consequently, to this article. It is a well-known fact that some diseases or conditions dominantly affect one gender or the other. There are the trivial ones, like prostate cancer or ovarian, cervical, uterine cancers. But there is a long list of diseases and condit...
Source: The Medical Futurist - May 12, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Future of Medicine Healthcare Policy Medical Education women female health under-reseached gender gap in healthcare Source Type: blogs

Wireless Implant for Anti-Cancer Photodynamic Therapy
Researchers at Texas A&M University created a wireless device that aims to illuminate and destroy residual tumor cells left after cancer resection. The device can be used by surgeons to illuminate the tumor bed after resection. It works in combin...
Source: Medgadget - April 28, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Oncology Radiology Surgery TAMU Source Type: blogs

Excitable Nanoparticles Destroy Endometriosis Lesions
Researchers at Oregon State University developed a nanoparticle system that can aid with the removal of endometrial lesions in a minimally invasive fashion. In endometriosis, endometrial tissue grows outside of the uterus, causing pain and affecting ...
Source: Medgadget - April 25, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Nanomedicine Ob/Gyn Radiology OregonState Source Type: blogs

Fight Aging! Newsletter, March 28th 2022
In conclusion, we summarized here evidence for a novel therapeutic approach to exploit the incredible ability of mitochondria to engage multifaceted neuroprotective stress response triggered by partial complex I inhibition. This approach promises relief for multiple human conditions, and to promote healthy aging to delay the onset of neurogenerative diseases, AD in particular, where age is the greatest risk factor. There is a mounting body of evidence generated in model organisms and humans in support of the safety of chronic application of complex I inhibitors. However, a better understanding of the molecular mechanisms i...
Source: Fight Aging! - March 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Cell-Loaded Beads Release Cytokines to Eradicate Tumors
In this study, we demonstrated that the ‘drug factories’ allow regulatable local administration of interleukin-2 and eradication of tumor in several mouse models, which is very exciting. This provides a strong rationale for clinical testi...
Source: Medgadget - March 21, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Oncology Source Type: blogs

Fight Aging! Newsletter, March 14th 2022
This study tests the feasibility of chronically elevating skeletal muscle NAD+ in mice and investigates the putative effects on mitochondrial respiratory capacity, insulin sensitivity, and gene expression. The metabolic effects of NR and PT treatment were modest. We conclude that the chronic elevation of skeletal muscle NAD+ by the intravenous injection of NR is possible but does not affect muscle respiratory capacity or insulin sensitivity in either sedentary or physically active mice. Our data have implications for NAD+ precursor supplementation regimens. Muscle Strengthening Activities in Later Life Correlate ...
Source: Fight Aging! - March 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Many Mediocre Cancer Therapies Become Much Better When More Targeted to Cancerous Tissues
One of the important areas of cancer research and development that appears to receive a great deal of attention and funding, but in practice seems slow to make it from the laboratory to the clinic, is the targeting of therapeutics to cancerous cells. Reductio ad absurdum, near any of dozens of existing chemotherapeutics would do the job of completely clearing tumors, with minimal to no side-effects, if one could only find a way to delivery tiny amounts of the therapeutic to every cancer cell while avoiding every healthy cell. The inability to target treatments this effectively is exactly why cancer remains such a problem. ...
Source: Fight Aging! - March 9, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, January 24th 2022
In conclusion, senolytic drugs have shown promising results in the elimination of senescent cells and in alleviating various diseases in animal models. However, in patients, there is a paucity in data on the efficacy and safety of senotherapeutics from clinical trials, including systemic effects and side-effects. In this regard it is important to assess the specificity of senolytics in killing targeted senescent cells and their cytotoxic effects, to identify reliable markers for intervention responses, to elucidate interactions with comorbidities and other drugs, and to standardise administration protocols. FOXO3...
Source: Fight Aging! - January 23, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Gameto Raises $20M at an Early Stage to Focus on Ovarian Aging
One of the signs of investor enthusiasm for an industry is the existence of projects that raise significant funding at a very early stage of their development. We're seeing that happen for cellular reprogramming, but companies started by well-connected individuals in other parts of the longevity industry are now raising a great deal of funding in early preclinical stages of development. This suggests that we will continue to see a growing influx of capital into the development of ways to treat aging as a medical condition, pulling more research projects out of the constraints of academia and into an environment of greater ...
Source: Fight Aging! - January 18, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, December 27th 2021
We report that whereas microglia are characterized by marked gene-level alterations related to negative regulation of protein phosphorylation and phagocytic vesicles, astrocytes show activation of enzyme- or peptidase-inhibitor signaling after detectable changes in BBB permeability. We also identify several genes enriched in these pathways that are notably altered after BBB breakdown. Our data reveal that microglia and astrocytes play an active role in maintaining BBB stabilization and corralling infiltrating cells, and thus might potentially function in ameliorating the lesions and neurologic disabilities in CNS diseases....
Source: Fight Aging! - December 26, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Breast Cancer Screening: We Can Do Better
The three risk assessment tools now in use fall far short. Using the latest deep learning techniques, investigators are developing more personalized ways to locate women at high risk.John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article.The promise of personalized medicine will eventually allow clinicians to offer individual patients more precise advice on prevention, early detection and treatment. Of course, the operative word iseventually.A closer examination of the screening tools available to detect breast c...
Source: Life as a Healthcare CIO - August 31, 2021 Category: Information Technology Source Type: blogs

Can some postmenopausal women with breast cancer skip chemotherapy?
Breast cancer remains the most common cancer among women. In the last two decades, the treatment of breast cancers has become personalized. This has been possible due to the subtyping of breast cancers. Breast cancers have been subtyped based on the receptors on the breast cancer cell. The most clinically significant receptors — those that have targeted therapies — are the estrogen and progesterone receptors and the human epidermal growth factor receptor 2 (HER2). Cancers that have the estrogen and progesterone receptors are termed hormone receptor (HR)-positive cancers. The development of hormone therapy for HR-positi...
Source: Harvard Health Blog - April 15, 2021 Category: Consumer Health News Authors: Salewa T. Salewa Oseni, MD Tags: Cancer Medical Research Women's Health Source Type: blogs

Accelerating the Development of Tests for Endometriosis and Cancer
NIGMS’ Small Business Technology Transfer (STTR) program works toward more effective methods for patient screening, diagnosis, and treatment. Translating lab discoveries into health care products requires large investments of time and resources. Through the STTR Regional Technology Transfer Accelerator Hubs for IDeA States program, NIGMS helps researchers interested in transitioning their discoveries and/or inventions into products. Here are the stories of three researchers working with the XLerator Hub, which funds projects in the southeastern United States and Puerto Rico. Ending Diagnostic Delays for Endomet...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 7, 2021 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Injury and Illness Cancer Diseases Profiles Scientific Process Source Type: blogs

TOP 10 Dangers Of Digital Health
Thanks to the advent of digital health, the future of medicine is truly exciting. With technological advancements that democratise access to care, better treatments are accessible to people than ever before. Breakthrough research and medical developments have eradicated deadly diseases and turned others into manageable conditions. But the very developments that propel healthcare to the 21st century bring their own share of hazards to the field. From the elimination of privacy through hacked medical devices to bioterrorism, there are signs of alarming trends that few take seriously. Nevertheless, we must generate discussion...
Source: The Medical Futurist - March 30, 2021 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Bioethics Biotechnology Digital Health Research Healthcare Policy Nanotechnology Security & Privacy Telemedicine & Smartphones algorithm ecg google smartwatch wearables GC1 wannacry ransomw Source Type: blogs

Top 10 Hazards Of Technology In Digital Health
Thanks to the advent of digital health, the future of medicine is truly exciting. With technological advancements that democratise access to care, better treatments are accessible to people than ever before. Breakthrough research and medical developments have eradicated deadly diseases and turned others into manageable conditions. But the very developments that propel healthcare to the 21st century bring their own share of hazards to the field. From the elimination of privacy through hacked medical devices to bioterrorism, there are signs of alarming trends that few take seriously. Nevertheless, we must generate discussion...
Source: The Medical Futurist - March 30, 2021 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Bioethics Biotechnology Digital Health Research Healthcare Policy Nanotechnology Security & Privacy Telemedicine & Smartphones algorithm ecg google smartwatch wearables GC1 wannacry ransomw Source Type: blogs