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The FDA approval of 23andMe ’s BRCA test: What it means for you
The approval by the Food and Drug Administration of 23andMe’s BRCA test is bound to create a discussion about the merits and pitfalls of direct to consumer genetic testing for cancer risk.
It is also going to add fuel to a growing fire about how we as a nation assess genetic risks for cancer, and whether society is prepared for what is inevitably going to become a genomic-influenced and informed culture of health.
From my perspective, as someone who has given considerable thought to these questions over the past several years, there are no easy answers.
The announcement was straightforward: the FDA approved a test t...
Source: Kevin, M.D. - Medical Weblog - March 18, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/j-leonard-lichtenfeld" rel="tag" > J. Leonard Lichtenfeld, MD < /a > Tags: Conditions Genetics Oncology/Hematology Source Type: blogs
The challenge in oncology: balancing hope and reality
Part of the challenge in oncology is the balance between hope and reality, and that is probably the most important thing to strive for for patients living with metastatic disease. Often times, the important conversations relate to treatment options, goals of care, and patient preferences (i.e., how frequent the visits to the doctor and for infusions, side effect profiles, and the important events in their lives which they do not want to miss). Yet, some of the most important are also the ones I struggle with the most.
This was the case with Laynie*. She and I met when she was diagnosed with ovarian cancer. I had hoped to c...
Source: Kevin, M.D. - Medical Weblog - March 14, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/don-s-dizon" rel="tag" > Don S. Dizon, MD < /a > Tags: Conditions Oncology/Hematology Source Type: blogs
Mr. and Mrs. Wheat Belly
Men and women follow the Wheat Belly lifestyle and can undergo important and sometime startling hormonal changes. Though results vary with stage of life—young adults, middle-aged, older—there are a variety of hormonal changes that women and men typically experience, some in concert, others independently. Such hormonal shifts can be powerful and part of the health-restoring menu of changes that develop with this lifestyle. They can even improve a relationship in a number of ways, both physically and emotionally, especially if we weave in some of the newer Wheat Belly/Undoctored concepts and practices such as oxy...
Source: Wheat Belly Blog - March 13, 2018 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle estradiol estrogen hormonal hormones Inflammation low-carb oxytocin testosterone Thyroid Weight Loss Source Type: blogs
Fight Aging! Newsletter, February 19th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - February 18, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Nanomachines Create Clots Inside Vessels Feeding Cancer Tumors
Researchers from Arizona State University and National Center for Nanoscience and Technology of the Chinese Academy of Sciences have developed a remarkable new way of killing tumors. They’ve developed robot-like nanoscale devices that cling to ...
Source: Medgadget - February 16, 2018 Category: Medical Devices Authors: Editors Tags: Nanomedicine Oncology Source Type: blogs
DNA Machinery that can Sabotage the Blood Supply of Tumors
Researchers have been building simple molecular machines out of DNA for some years now. This approach to molecular machinery is well suited to applications that involve conditional activation based on the proteins present in the surrounding environment; a lot of the necessary functional parts already exist in DNA and just have to be assembled in the right way. The Oisin Biotechnologies cell-killing technology is a smaller example of the type than the approach here, in which sizable DNA containers are constructed. They carry a cargo that will disrupt local blood flow, and are triggered into opening by cancerous cell surface...
Source: Fight Aging! - February 14, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Weaponizing the Biochemistry of Huntington ' s Disease as a General Cancer Therapy
An interesting observation that has arisen over the years of epidemiological study of human age-related disease is that there are a number of distinct inverse relationships between incidence of cancer and incidence of some forms of neurodegeneration. This was in the news a few years ago in the case of Alzheimer's disease for example. Why would people with a higher risk of cancer suffer lower rates of Alzheimer's disease, however? We can only speculate at this point, but the more recent discovery I'll point out here adds fuel for that speculation. The Alzheimer's-cancer relationship is modest in size and somewhat complex in...
Source: Fight Aging! - February 14, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Intermountain Precision Genomics to Develop Hereditary Cancer Gene Panels
The emerging healthcare model which is dominated by a small number of very large health systems will be characterized, in part, by in-house, sophisticated genomic and molecular lab testing by these systems. This is because these large health systems will have the capital to invest in their own"laboratories of excellence" within their system. Such is the case withIntermountain Healthcare which has its own in-house genomics laboratory called Intermountain Precision Genomics. Intermountain Health is one of the giant health systems with 37,000 employees, 22 hospitals, and more than 185 clinics. Here is the miss...
Source: Lab Soft News - February 13, 2018 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Clinical Lab Industry News Clinical Lab Testing Genomic Testing Healthcare Business Healthcare Innovations Lab Industry Trends Lab Processes and Procedures Medical Consumerism Pathology Informatics Reference Laboratories Test Kits and Source Type: blogs
Genetic Testing and Non-High Risk
A person can be considered medically high risk due to their or a family member ' s medical history. If you are considered medically as high risk, you get popped into the category of give them lots more medical attention and ' lovely ' tests.Now withthe progress of genomic testing, its no longer a big expensive, rare proposition. However, why do we only test the high risk people? These are the people who already know they are high risk. But that leaves a lot of people who don ' t know they are high risk and could be. This doesn ' t make sense. Some new research asks if it wouldn ' t it make more sense to test more peop...
Source: Caroline's Breast Cancer Blog - February 10, 2018 Category: Cancer & Oncology Tags: breast cancer cancer prevention genetic testing ovarian cancer Source Type: blogs
Fight Aging! Newsletter, January 22nd 2018
In conclusion, death is a natural part of human existence, but human progress is essentially a story of overcoming undesirable natural limits. In the near future, technological progress might make it possible to stop natural biological death. Should humankind embrace such technology? Yes: Even though such technology would not be without risks, the risks are almost certainly manageable. The benefits of ending natural death, on the other hand, are immense. Death is an obstacle that is slowing down human progress. If we remove that obstacle, humankind could increase the speed of both its moral and its epistemic progress.
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Source: Fight Aging! - January 21, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Remembering the Late Professor Juergen Willmann
Esteemed and highly innovative researcher and Stanford University professor of radiology Juergen Willmann, MD, died in a car accident on January 8. He was 45 years-old. Originally from Germany, Willmann spearheaded research using microbubbles and ultrasound that could be used to identify tumors and target the transmission of medication. His work was already being implemented in clinical imaging trials with humans to detect breast and ovarian cancer. He also won the 2017 Distinguished Investigator Award from the Academy for Radiology& Biomedical Imaging Research. Not only revered for his pioneering accomplishments, Will...
Source: radRounds - January 19, 2018 Category: Radiology Authors: Julie Morse Source Type: blogs
Recent Papers on the Mitochondrial Contribution to Aging
Mitochondria are the power plants of the cell, a herd of self-replicating structures evolved from ancient symbiotic bacteria, now fully integrated into the cell. Their primary task is the production of chemical energy stores, an energetic process that produces damaging reactive molecules as a side-effect. Much of the original bacterial DNA of the distant ancestors of today's mitochondia has migrated to the cell nucleus, leaving only a tiny remnant genome in the mitochondria themselves. When looking across species with widely divergent life spans, researchers have found good correlations between species life span and some c...
Source: Fight Aging! - January 16, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
What ’s the latest on estrogen use in post-menopausal women?
Estrogen is a miracle drug for many women who experience the drenching sweats, sexual dysfunction and frustrating brain betrayals associated with entering menopause. It comes in expensive patches, less expensive pills or injections, as well as vaginal creams or rings. It has gone in and out of favor with the medical community for decades.
Estrogen is the main ingredient in most birth control pills and has been studied extensively in that context as well as in the setting of women whose ovaries have ceased to produce it as they age. It can increase the risk of migraines, blood clots in the legs or lungs; it can cause benign...
Source: Kevin, M.D. - Medical Weblog - January 11, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/janice-boughton" rel="tag" > Janice Boughton, MD < /a > Tags: Conditions OB/GYN Source Type: blogs
Fight Aging! Newsletter, January 1st 2018
Discussion of advocacy for the cause is a usual feature of our community, as we try things and attempt to make progress in persuading the world that rejuvenation research is plausible, practical, and necessary. There are more people engaged in advocacy now than at any time in the past decade, and so discussions of strategy come up often. New ventures kicked off in 2017 include the Geroscience online magazine, and among the existing ventures the LEAF / Lifespan.io volunteers seem to be hitting their stride. The mainstream media continues to be as much a hindrance as a help, and where it is a help you will usually find Aubre...
Source: Fight Aging! - December 31, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Look Back at the Science of Longevity and Advocacy for Rejuvenation in 2017
Discussion of advocacy for the cause is a usual feature of our community, as we try things and attempt to make progress in persuading the world that rejuvenation research is plausible, practical, and necessary. There are more people engaged in advocacy now than at any time in the past decade, and so discussions of strategy come up often. New ventures kicked off in 2017 include the Geroscience online magazine, and among the existing ventures the LEAF / Lifespan.io volunteers seem to be hitting their stride. The mainstream media continues to be as much a hindrance as a help, and where it is a help you will usually find Aubre...
Source: Fight Aging! - December 29, 2017 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs
