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More about Virtue Sweetener
Because I wanted a benign and healthy way for followers of the Wheat Belly lifestyle to recreate dishes such as chocolate chip cookies, cheesecake, and pies with none of the health problems of grains or sugars, I helped Wheat-Free Market develop its Virtue Sweetener  product. Yes, you could do without such sweeteners. But I learned long ago when I introduced Wheat Belly concepts to patients in my cardiology practice that having options while entertaining friends, during holidays, and pleasing kids was important for staying on course on this lifestyle. Before I understood how to use such natural sweeteners, patients would ...
Source: Wheat Belly Blog - March 10, 2017 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle diabetes erythritol gluten grains Inflammation insulin keto low-carb monk fruit natural virtue sweetener Source Type: blogs

New Technique for Cheaper, More Efficient Single Cell Sequencing
Single-cell sequencing has shown a lot of promise in identifying genetic differences between cells in a given tissue sample. It is particularly useful for understanding heterogeneity and evolution in resected tumors, and is increasingly used for impr...
Source: Medgadget - February 23, 2017 Category: Medical Equipment Authors: Mohammad Saleh Tags: Genetics Oncology Pathology Source Type: blogs

Insulin is a carcinogen
The science is clear: Insulin is carcinogenic. People with insulin resistance, metabolic syndrome/pre-diabetes, and type 2 diabetes have high levels of blood insulin, typically many times higher than normal. People with these conditions are at increased risk for various cancers such as breast, colon, prostate, and pancreas (Gallagher 2015). Type 2 diabetics are also more likely to die of their cancer than non-diabetics. While the cause-effect connection is due to a number of factors (high blood sugar, inflammation, high circulating estrogen levels, increased insulin-like growth factors, etc.), much of the increased cancer ...
Source: Wheat Belly Blog - February 20, 2017 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle cancer carcinogen diabetes gluten grains Inflammation insulin resistance Source Type: blogs

Fight Aging! Newsletter, January 30th 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - January 29, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Demonstration of Chimeric Tissue Farming: Mouse Pancreatic Tissue Grown in Rats
We examined them closely for the presence of any rat cells, but we found that the mouse's immune system had eliminated them. This is very promising for our hope to transplant human organs grown in animals because it suggests that any contaminating animal cells could be eliminated by the patient's immune system after transplant." Importantly, the researchers also did not see any signs of tumor formation or other abnormalities caused by the pluripotent mouse stem cells that formed the islets. Tumor formation is often a concern when pluripotent stem cells are used in an animal due to the cells' remarkable developmental plasti...
Source: Fight Aging! - January 26, 2017 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Office Space: When You Need More Space Than Office
“What am I doing here?” my mind raced. In an overheated cubicle with five other underemployed attorneys, frustration and disillusionment vied for supremacy. As my co-workers and I labored through the mind-numbing document review, sighs, grunts, and biting comments pierced the silence. Laboring in this dead-end job, a sense of despair wafted through the stuffy cubicle. I wanted to quit. But only after I shrieked in frustration. “Isn’t this why all of us went to law school?” I cracked. And, yes, groused. My co-workers grunted in agreement. Imbued with idealism, I anticipated a rewarding legal career — not one...
Source: World of Psychology - January 21, 2017 Category: Psychiatry & Psychology Authors: Matthew Loeb Tags: Happiness Industrial and Workplace Motivation and Inspiration Personal Achievement Career Change career success Day Job Despair Disillusionment Idealism Law School Personal Growth Underemployment Source Type: blogs

Metformin Acts through mTORC1
We report two elements absolutely required for the anti-growth properties of metformin: the nuclear pore complex (NPC), and acyl-CoA dehydrogenase family member 10 (ACAD10). These two metformin response elements were used to illuminate the major, biological pathway through which metformin induces its favorable effects. Remarkably, this ancient pathway unifies mitochondria, the NPC, mTORC1, and ACAD10 into a single signaling relay that mediates metformin's anti-aging effects in C. elegans and inhibits growth in C. elegans and human cancer cells alike. Link: http://www.cell.com/cell/fulltext/S0092-8674(16)31667-1
Source: Fight Aging! - December 30, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

BRCA-Positive Males at Higher Risk for Prostate and Pancreatic Cancer
Here is a brief description about BRCA gene mutations and the manner in which they predispose to various cancers (see: BRCA mutation):A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which are tumor suppressor genes....Harmful mutations in these genes may produce a hereditary breast-ovarian cancer syndrome in affected persons. Only 5-10% of breast cancer cases in women are attributed to BRCA1 and BRCA2 mutations..., but the impact on women with the gene mutation is more profound.Women with harmful mutations in either BRCA1 or BRCA2 have a risk of breast cancer that is about five times the n...
Source: Lab Soft News - December 21, 2016 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Clinical Lab Testing Healthcare Delivery Medical Education Medical Research Preventive Medicine Source Type: blogs

What We Learnt in Digital Health in 2016
In order to successfully move into 2017, it is crucial to draw the lessons of the past year in terms of successes, failures, remaining challenges and impenetrable obstacles in the field of digital health. Food for thought! An impulsive year in science and healthcare 2016 was a bold, busy and impulsive year in science and healthcare. Elon Musk, CEO of Tesla, founder of SpaceX and great visionary raised the stakes in astronautics again for the greatest pleasure of the fans of space flights. He promised no less than to take humanity to Mars as soon as possible (I explored the medical challenges of the project here). In July, ...
Source: The Medical Futurist - December 20, 2016 Category: Information Technology Authors: nora Tags: Future of Medicine artificial intelligence artificial pancreas big data Boston Dynamics digital health food scanner GC1 google Innovation precision medicine robotics theranos trackers virtual reality wearables Source Type: blogs

Temporarily Applying Pluripotency Reprogramming Factors to Adult Mice
Today's interesting news, doing the rounds in the popular press and being gleefully misinterpreted along the way, is that, working in mice, researchers have induced temporarily increased levels of the proteins used to reprogram normal cells into pluripotent stem cells. This produced a number of short term benefits to regeneration and metabolism, though the long-term results on life span remain to be assessed. Cancer and regeneration are two sides of the same coin, and it is thought that the characteristic decline in stem cell activity with age is part of an evolved balance between risk of cancer and risk of tissue failure....
Source: Fight Aging! - December 16, 2016 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

The Most Exciting Medical Technologies of 2017
It is almost a tradition for me to publish predictions for the coming year. I do not mean to disappoint you this year either, so here you find some thoughts about the top medical technologies of 2017. 2016 was a rich year for medical technology. Virtual Reality. Augmented Reality. Smart algorithms analysing wearable data. Amazing technologies arrived in our lives and on the market almost every day. And it will not stop in the coming year. The role of a futurist is certainly not making bold predictions about the future. No such big bet has taken humanity forward. Instead, our job is constantly analysing the trends shaping t...
Source: The Medical Futurist - December 15, 2016 Category: Information Technology Authors: nora Tags: Future of Medicine 3d printing AI artificial intelligence diabetes GC1 genetics Healthcare Innovation nutrigenomics Personalized medicine robotics wearables Source Type: blogs

Looking Back and Ahead in the Use of Pluripotent Stem Cells in Medicine
There are a few papers and commentaries that you might find interesting in the latest issue of Regenerative Medicine. The one I'll point out here offers a retrospective and a forecast for the use of pluripotent stem cells in medicine. It is authored by one of the more outspoken figures from the last decade of research and development, but is worth reading regardless of that point. All industries tend to follow what has come to be known as a hype cycle as they reach critical mass and transition into broad adoption and large scale development. Stem cell medicine as a whole had its initial peak of attention and overhyped expe...
Source: Fight Aging! - December 15, 2016 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Listen to your patient ’s story: It’s their diagnosis
Sir William Osler wasn’t exactly wrong when he said, “Listen to your patient, he is telling you the diagnosis.” But he didn’t mean it literally. His patients did not offer up esoteric and complete medical diagnoses on a silver platter. They left him clues in plain language that he listened to carefully in order to make the correct diagnosis. He penned his words in an era when medical information was scarce among non-medical people. There was no Dr. Google, Dr. Oz or Dr. House to educate the public about diseases or medical terminology a century ago. In a way, I think doctors today have to do more filtering of w...
Source: Kevin, M.D. - Medical Weblog - December 14, 2016 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/a-country-doctor" rel="tag" > A Country Doctor, MD < /a > Tags: Physician Primary care Source Type: blogs

Our Complicated Relationship With Viruses
Nearly 10 percent of the human genome is derived from the genes of viruses. Credit: Stock image. When viruses infect us, they can embed small chucks of their genetic material in our DNA. Although infrequent, the incorporation of this material into the human genome has been occurring for millions of years. As a result of this ongoing process, viral genetic material comprises nearly 10 percent of the modern human genome. Over time, the vast majority of viral invaders populating our genome have mutated to the point that they no longer lead to active infections. But they are not entirely dormant. Sometimes, these stowaway seq...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - November 21, 2016 Category: Research Authors: Chris Palmer Tags: Genetics Cancer Diseases DNA Evolutionary Biology Viruses Source Type: blogs

Smoking Linked to One-Fourth of All US Cancer Deaths
For me personally, the noxious habit of smoking does not seem to exist any more. At home and when traveling to large cities in the U.S., I rarely see anyone smoking. And yet, here's an article that indicates that smoking is linked to one-fourth of all U.S. cancer deaths (see:One-fourth of US cancer deaths linked with 1 thing: smoking). Below is an excerpt from it:Cigarettes contribute to more than 1 in 4 cancer deaths in the U.S. The rate is highest among men in Southern states where smoking is more common and the rules against it are not as strict. The American Cancer Society study found the hi...
Source: Lab Soft News - November 15, 2016 Category: Laboratory Medicine Authors: Bruce Friedman Tags: General Healthcare Medical Consumerism Medical Education Medical Research Preventive Medicine Public Health Informatics Source Type: blogs