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Join Dr. Davis ’ Infinite Health Boot Camp January 5th to the 14th
Undoctored is now Dr. Davis Infinite Health (www.DrDavisInfiniteHealth that goes live in early January) as its name suggests, puts personal control over health back in your hands. We continue many of the strategies of the Wheat Belly lifestyle but expand them with lessons learned through this worldwide experience, while adding new dimensions and practices. While we make the transition to Dr. Davis Infinite Health and away from Undoctored, the concepts and practices remain the same. The Dr. Davis’ Wild, Naked, and Unwashed program causes you to revert back to the way humans were supposed to be eating and living all ...
Source: Wheat Belly Blog - December 22, 2021 Category: Cardiology Authors: April Duval Tags: Open Undoctored Source Type: blogs

Join the Undoctored Boot Camp January 5th to the 14th
Undoctored, as its name suggests, puts personal control over health back in your hands. We continue many of the strategies of the Wheat Belly lifestyle but expand them with lessons learned through this worldwide experience, while adding new dimensions and practices. The Undoctored Wild, Naked, and Unwashed program causes you to revert back to the way humans were supposed to be eating and living all along to mimic the behavior and health of primitive people who have virtually no modern diseases such as diabetes, colon cancer, and obesity (still lived to old age if they did not succumb to injury or infection).  Learn: How...
Source: Wheat Belly Blog - December 22, 2021 Category: Cardiology Authors: April Duval Tags: Open Undoctored Source Type: blogs

Food Intolerances: A Warning of Bad Things Ahead
I’ve recently discussed how the majority of food intolerances, whether to FODMAPs, histamine, nightshades, fructose, etc., are really manifestations of dysbiosis and SIBO. Here is another way to view these phenomena: Food intolerances are your body’s signal to you that serious deterioration in your health is coming. In other words, if all you do is choose to reduce or eliminate the offending food, you are still left with the massive disruption of your intestinal microbiome that caused the food intolerance in the first place, along with increased intestinal permeability and endotoxemia. So say you eliminate ferm...
Source: Wheat Belly Blog - November 1, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open microbiota prebiotic probiotic sibo small intestinal bacterial super gut undoctored wheat belly Source Type: blogs

Fight Aging! Newsletter, September 27th 2021
This study provides causal evidence of a lipoprotein-Aß /capillary axis for onset and progression of a neurodegenerative process. The Staggering Ongoing Cost of Failing to Aggressively Pursue the Development of Rejuvenation Therapies https://www.fightaging.org/archives/2021/09/the-staggering-ongoing-cost-of-failing-to-aggressively-pursue-the-development-of-rejuvenation-therapies/ No feasible amount of funding that could be devoted to the research and development of rejuvenation therapies would be too much. If near all other projects were dropped, and institutions radically retooled on a short term basis...
Source: Fight Aging! - September 26, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Prevention of colon cancer begins . . . in the mouth?
The post Prevention of colon cancer begins . . . in the mouth? appeared first on Dr. William Davis.
Source: Wheat Belly Blog - September 22, 2021 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle bowel flora microbiota undoctored Source Type: blogs

I Am a Decision Maker, Not a Bookkeeper
By HANS DUVEFELT Perhaps it is because I love doctoring so much that I find some of the tools and tasks of my trade so tediously frustrating. I keep wishing the technology I work with wasn’t so painfully inept. On my 2016 iPhone SE I can authorize a purchase, a download or a money transfer by placing my thumb on the home button. In my EMR, when I get a message (also called “TASK” – ugh) from the surgical department that reads “patient is due for 5-year repeat colonoscopy and needs [insurance] referral”, things are a lot more complicated, WHICH THEY SHOULDN’T HAVE TO BE! For this routine task, I can...
Source: The Health Care Blog - September 20, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Primary Care EMR Hans Duvefelt Source Type: blogs

Fight Aging! Newsletter, September 13th 2021
In this study, mature DCs (mDCs), generated from the GM-CSF and IL-4 induced bone marrow cells, were intravenously injected into wild-type mice. Three days later, assays showed that the mDCs were indeed able to return to the thymus. Homing DCs have been mainly reported to deplete thymocytes and induce tolerance. However, medullary TECs (mTECs) play a crucial role in inducing immune tolerance. Thus, we evaluated whether the mDCs homing into the thymus led to TECs depletion. We cocultured mDCs with mTEC1 cells and found that the mDCs induced the apoptosis and inhibited the proliferation of mTEC1 cells. These effects were onl...
Source: Fight Aging! - September 12, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Mitochondrial-Derived Peptides as Targets for Cardiovascular Disease Therapies
This review takes a look at a number of peptides related to mitochondrial function, and which are thought to potentially provide therapeutic benefit. Some are interesting in the context of aging. As is the case for most peptides with enough scientific literature to justify a review paper, availability and use is somewhat ahead of the science. Peptide manufacture is easy enough and cheap enough that most studied peptides can be purchased from established manufacturers. That certainly doesn't mean that they are in fact useful at the end of the day! This marketplace is very much like the supplement marketplace in that respect...
Source: Fight Aging! - September 10, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

What is Primary Health?
I’ve been writing a blog post on this topic for a few months.  It’s gone through several iterations and has survived a half-dozen friendly editors.  This post isn’t that post, which still needs honing and will follow in the coming days.  This post is the personal prelude – the why that perhaps is important to share before the what. Simon Sinek says we should start with why.  Here goes: My decision to go to medical school was long-delayed.  Indeed – I took no science classes in college – assuring myself that I would not follow the path of my father and grandfathers – all of wh...
Source: Docnotes - August 25, 2021 Category: Primary Care Authors: Jacob Tags: Health Uncategorized Source Type: blogs

Fight Aging! Newsletter, August 23rd 2021
In this study, we used the UK Biobank (n = 440,185) to resolve previous ambiguities in the relationship between serum IGF-1 levels and clinical disease. We examined prospective associations of serum IGF-1 with mortality, dementia, vascular disease, diabetes, osteoporosis, and cancer, finding two generalized patterns. First, IGF-1 interacts with age to modify risk in a manner consistent with antagonistic pleiotropy; younger individuals with high IGF-1 are protected from disease, while older individuals with high IGF-1 are at increased risk for incident disease or death. Second, the association between IGF-1 and risk ...
Source: Fight Aging! - August 22, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Improved Manipulation of " Eat Me " and " Don ' t Eat Me " Markers in the Context of Cancer
One of the more interesting discoveries of the past few decades in cancer research has been the identity of surface markers such as CD47 that normally act to protect important cells from being attacked and destroyed by immune cells - a "don't eat me" signal. Cancers abuse such mechanisms in a variety of ways, both directly, in cancerous cells, and indirectly, via subversion of regulatory immune cells that are protected by such surface markers, in order to suppress the immune response to the cancer. Targeting CD47 has proven a promising approach to the treatment of cancer, but it has side-effects. There are always necessary...
Source: Fight Aging! - August 19, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Strength Training and Aerobic Exercise Reduce Cancer Mortality
Researchers here note that undertaking strength training and aerobic exercise acts to reduce mortality due to cancer, to a similar degree as these activities are known to reduce all cause mortality in later life. The mechanisms involved are likely diverse, but it is worth noting that (a) muscle tissue is metabolically active in beneficial ways, such that more muscle is better than less muscle, (b) better immune function is linked to exercise, and immune surveillance is critical to cancer prevention, and (c) exercise helps to reduce chronic inflammation, where chronic inflammation helps to drive the establishment and develo...
Source: Fight Aging! - August 17, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Should Your Parent Risk an Anesthesia Disaster or Forego Surgery?
  Photo credit Niklas Hamann Just last week a reader asked me whether she should try to sway her mother, who had colon cancer, toward surgery. Her mother, 87, was diagnosed with colon cancer and given the choice of surgery and chemotherapy or letting it alone. If she chose not to have surgery, she could still have chemotherapy and radiation, though she was told that treatment wasn't apt to help a great deal. As expected, the daughter was distraught. She was seeking help in determining what her responsibility to her mother is. The woman mentioned that her mother was mentally sharp, so I told her that, in my opinion......
Source: Minding Our Elders - August 10, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

Fight Aging! Newsletter, August 2nd 2021
This study aimed to determine the association between: (i) cognitive decline and bone loss; and (ii) clinically significant cognitive decline on Mini Mental State Examination (MMSE) over the first 5 years and subsequent fracture risk over the following 10 years. A total of 1741 women and 620 men aged ≥65 years from the population-based Canadian Multicentre Osteoporosis Study were followed from 1997 to 2013. Over 95% of participants had normal cognition at baseline. After multivariable adjustment, cognitive decline was associated with bone loss in women but not men. Approximately 13% of participants experienced sign...
Source: Fight Aging! - August 1, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Peptide Coated Nanoparticles as a Basis for a Non-Invasive Test for Cancer
A reliable, low-cost means of early detection of cancer would be of great benefit. Approaches to the treatment are advancing to the point at which very early stage cancer has a high rate of survival, and the side-effects of treatments for early stage cancer are becoming less onerous. In the ideal world, a yearly physical would include a low-cost cancer screen that robustly detects even small volumes of cancerous tissue. Various approaches are under development, such as those based on identification of signal molecules in the bloodstream. The alternative approach noted here, based on the use of engineered nanoparticles, is ...
Source: Fight Aging! - July 27, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs