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Fight Aging! Newsletter, February 19th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
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Source: Fight Aging! - February 18, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Join the Undoctored Revolution
Let’s take back control over personal health. Share this to expose healthcare for the corrupt enterprise it is.
Imagine that you receive a letter in the mail stating “In order to retain your right to freedom of speech, you will be billed $10,000 per year every year for the rest of your life.”
You would be—-understandably-—outraged. Freedom of speech in America is precious, something Americans have waged wars to defend, something we now view as a basic right, no financial price required to maintain it. It should be free and available to everyone regardless of religion, color, political leanings, or income.
...
Source: Wheat Belly Blog - February 9, 2018 Category: Cardiology Authors: Dr. Davis Tags: Undoctored Wheat Belly Lifestyle diy health Dr. Davis grain-free healthcare Source Type: blogs
Fight Aging! Newsletter, February 5th 2018
In this study, we tested the hypothesis that Gbp1 plays a role in regulating immunometabolism and senescence of macrophages. We found that Gbp1 was mainly expressed in macrophages, but not adipocytes in response to IFNγ/LPS stimulation; Gbp1 expression was significantly decreased in inguinal white adipose tissue (iWAT) of high-fat diet (HFD)-fed and aged mice. We also observed that downregulation of Gbp1 in macrophages resulted in M1 polarization and impairment of mitochondrial respiratory function possibly via disrupting mitophagy activity. Moreover, macrophages with downregulated Gbp1 displayed dampened glycolysis and e...
Source: Fight Aging! - February 4, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Be ketotic . . . but only sometime
Achieving ketosis by engaging in a very low-carbohydrate, high-fat lifestyle is an effective means of losing weight, breaking insulin and leptin resistance, reversing type 2 diabetes and fatty liver, reducing blood pressure, reversing the inflammation of visceral fat, and may even cause partial or total remission of selected cancers.
So what’s the problem?
The problem comes when people remain ketotic for extended periods. We know with confidence that long-term ketosis poses substantial risk for health complications because thousands of children have followed ketogenic diets over the years as a means of suppressing in...
Source: Wheat Belly Blog - February 2, 2018 Category: Cardiology Authors: Dr. Davis Tags: Undoctored Wheat Belly Lifestyle Source Type: blogs
Fight Aging! Newsletter, January 29th 2018
In conclusion, the present study demonstrated that TIGIT is a prominent negative immune regulator involved in immunosenescence. This novel finding is highly significant, as targeting TIGIT might be an effective strategy to improve the immune response and decrease age-related comorbidities.
Delivery of Extracellular Vesicles as a Potential Basis for Therapies
https://www.fightaging.org/archives/2018/01/delivery-of-extracellular-vesicles-as-a-potential-basis-for-therapies/
Here I'll point out a readable open access review paper on the potential use of extracellular vesicles as a basis for therapy: harveste...
Source: Fight Aging! - January 28, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Does Donald Trump Have Heart Disease?
By SAURABH JHA
According to the WHO definition of health, which is “a state of complete physical, mental, and social well-being, and not merely the absence of disease and infirmity,” several million Americans became unhealthy on Tuesday November 8th, 2016 as Florida folded to Trump. As Hillary’s prospects became bleaker many more millions, particularly those on Twitter, lost their health. The WHO sets a high bar for health. It is easier for a camel to pass through the eye of a needle than for a person on social media to be in “complete mental and social well-being.”
Whilst WHO has set a high bar for health, moder...
Source: The Health Care Blog - January 24, 2018 Category: Consumer Health News Authors: at RogueRad Tags: Uncategorized Source Type: blogs
Specific Risk Factors can Appear to Decline in Importance in Later Life, as the High-Risk Individuals are Already Dead
As this 40-year longitudinal study illustrates, when measuring the correlation between specific risk factors on specific forms of mortality, their influence can appear to decline in later life. That is to say that mortality rates keep rising with advancing age, but they are less obviously influenced by any one cause for a given cohort of individuals. This effect occurs because the fatal consequences of a particular form of age-related dysfunction will tend to occur earlier in old age for individuals with the highest risk. With each passing year, a given age group is ever more made up of resilient survivors, people who - fo...
Source: Fight Aging! - January 9, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Telomere Length as Presently Measured is Not a Useful Biomarker of Aging
Average telomere length is currently usually measured in leukocytes obtained from a blood sample. When considering the statistics of a sizable population, average telomere length tends to trend downwards over a lifetime. Telomeres form a part of the complex mechanism that limits somatic cell replication: they shorten with each cell division, and cells with very short telomeres self-destruct or become senescent, ceasing to replicate in either case. Stem cells deliver a supply of new somatic cells with long telomeres to make up the numbers. So average telomere length is a blurred measure of stem cell activity and pace of cel...
Source: Fight Aging! - December 29, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, December 18th 2017
In this study, we asked people in an open-ended way about their desire for longer life: Would you like to have more time? What age would you like to become? This was something more specific than asking about a preference for survival without reference to any length of time; about one's plans for the future; or whether people see the future as open or limited, as in studies of future time perspective. Our attempt was to discover whether there were preferred temporal spans with which older adults framed their futures and plans.
The two-question series about extra years and desired age ("How old would you like to becom...
Source: Fight Aging! - December 17, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
What Diet Works Best, Part 1: Put Down The Grapefruit
Why is chosing a diet so hard?
The information we receive about diets, food, and nutrition is confusing. Millions of dollars are spent on weight loss schemes that never last. So, how do you choose a diet that will work? This post is the first in a series of articles exploring questions to ask when choosing a diet. Here goes…
Does the grapefruit diet work?
It’s not the grapefruit’s fault. This morning, however, I had three emails touting a celebrity with a “new” grapefruit diet to get in shape for the holidays. This sort of thing drives me crazy. First, celebrities aren’t e...
Source: Embrace Your Heart Wellness Initiative - December 13, 2017 Category: Cardiology Authors: Eliz Greene Tags: Award Winning Blog Heart Health grapefruit healthy diet nutrition Source Type: blogs
Death Receptors as Biomarkers for Cardiovascular Mortality
Researchers here present evidence for the appropriately named death receptors to be biomarkers for cardiovascular disease risk, an indirect measure of the damage accumulating in the vascular system over the course of aging, and its effects on cellular biochemistry. The research community is very interested in establishing reliable, easily measured biomarkers that relate to age-related disease, mortality, and known mechanisms of aging. The more that exist, the more likely it is that these biomarkers can be combined in some algorithmic way to generate a more precise overall biomarker of biological age - something that can be...
Source: Fight Aging! - December 12, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, December 11th 2017
In this study, we used the Clinical Practice Research Datalink (CPRD) to estimate clinically measured SBP and DBP trajectories for 20 years prior to death, for individuals dying at 60 years and older. Second, we compared the linear SBP trends for years 10 to 3 years before death in patients who died and age- and sex-matched controls who survived at least 9 years. These approaches aimed to separate age from end-of-life associations, and avoid healthy survivor biases.
Twenty years before death, estimated mean SBPs increased with increasing age at death (60-69 years, 139.5 mm Hg; ≥90 years, 150.0 mm Hg). All age-at-d...
Source: Fight Aging! - December 10, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The surprising way email can make you a better doctor
Doctors, you need to improve the patient experience. Your intentions are there, but patients are starving for more.
Office visits offer definitive evidence that patients need to change. Tests results provide real data to make patients aware of health concerns. This is a clear and obvious starting point.
But after this information is gathered, the framework of change gets cloudy. Doctors go from offering clear and focused details like:
” You have high blood pressure.”
“Your BMI is high.”
“You need to lose weight.”
“You need to lower your cholesterol.”
“You are increasing your risk of cancer.”
“Your LDL...
Source: Kevin, M.D. - Medical Weblog - December 5, 2017 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/joe-bellistri" rel="tag" > Joe Bellistri < /a > Tags: Tech Cardiology Practice Management Primary Care Source Type: blogs
The Six Worst U.S. Health Disasters of the Last 50 Years
Up until the first half of the twentieth century, large-scale health disasters were mostly due to natural causes (earthquakes, volcanoes, hurricanes, etc.) or infections (e.g., smallpox, influenza epidemics, cholera). But something peculiar happened as we entered the second half of the century: Health disasters due to natural causes became dwarfed by large-scale health disasters that are man-made.
Here’s a list of the Six Worst U.S. Health Disasters of the Last 50 Years, mostly man-made phenomena that have exacted huge tolls: widespread disease, premature death, poorly managed (though nonetheless highly profitable fo...
Source: Wheat Belly Blog - December 2, 2017 Category: Cardiology Authors: Dr. Davis Tags: Undoctored Wheat Belly Lifestyle autoimmune gluten grain-free grains Inflammation low-carb Weight Loss Source Type: blogs
The Secrets in Your Triglycerides
Of the four measures available on any standard cholesterol blood panel, triglycerides are the most neglected. Yet that one value contains a wealth of information and insight into your health, information about your diet, insulin status, even a sign that you could have fatty liver–but I’ll bet, of the many times you’ve had a cholesterol panel drawn, your doctor never thought to even mention any of this.
Don’t let the medical system’s misguided obsession with cholesterol (because of the influence and marketing of the drug industry) keep you from learning and benefiting from the secrets in your t...
Source: Wheat Belly Blog - November 30, 2017 Category: Cardiology Authors: Dr. Davis Tags: Undoctored Wheat Belly Lifestyle cholesterol diabetes gluten-free grain-free Inflammation low-carb triglycerides Weight Loss Wheat Belly Total Health Source Type: blogs
