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Should Patients Diagnosed With Alzheimer ’s Or Dementia Be Able To Choose Assisted Suicide?
I was on KPCC (NPR) in Los Angeles, yesterday, to address the question "Should Patients Diagnosed With Alzheimer’s Or Dementia Be Able To Choose Assisted Suicide?" A recent op-ed in the L.A. Times titled, “My friend has dementia and wants to end her life. California’s assisted-suicide law excludes her,” shines a light on the complexities of expanding the state’s law beyond patients with a cancer diagnosis or terminal illness. The law, passed in 2015 and modeled after a 1997 Oregon statute, allows physicians to give lethal drugs to mentally competent adults when they’re faced with a termi...
Source: blog.bioethics.net - February 26, 2020 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care syndicated Source Type: blogs

Fight Aging! Newsletter, February 24th 2020
In conclusion, taller body height at the entry to adulthood, supposed to be a marker of early-life environment, is associated with lower risk of dementia diagnosis later in life. The association persisted when adjusted for educational level and intelligence test scores in young adulthood, suggesting that height is not just acting as an indicator of cognitive reserve. A Comparison of Biological Age Measurement Approaches https://www.fightaging.org/archives/2020/02/a-comparison-of-biological-age-measurement-approaches/ Researchers here assess the performance of a range of approaches to measuring biological...
Source: Fight Aging! - February 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Gentler Approach to Transplanting Young Hematopoietic Stem Cells into Old Mice Modestly Extends Life Span
Stem cell populations become damaged and dysfunctional with age. Some of this is issues with the stem cells themselves, and some of this results from problem with the signaling environment and function of the stem cell niche. Which of these factors is more important likely varies by stem cell population. Among the best studied of stem cell types, the evidence suggests that muscle stem cells remain capable in old age, but become ever more quiescent, while hematopoietic stem cells become damaged and dysfunctional, unable to perform. Hematopoietic stem cells reside in the bone marrow and are responsible for generating blood a...
Source: Fight Aging! - February 20, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Inside Schizophrenia: Schizophrenia in Women
Often we don’t really consider gender dynamics in treatment or medication. A lot of medications are only tested on men because of the risk of pregnancy, etc. This means there are whole drugs that have made it to market that may not have ever been tested with women. Schizophrenia affects women in many different ways than men. In this episode schizophrenic Rachel Star Withers and cohost Gabe Howard discuss differences in age, symptoms, treatments, lifestyle, parenthood in the genders as they experience schizophrenia. Dr. Hayden Finch joins to explain the medical side.  Highlights in “Schizophrenia in WomenR...
Source: World of Psychology - February 19, 2020 Category: Psychiatry & Psychology Authors: Rachel Star Withers Tags: Inside Schizophrenia Mental Health and Wellness Women's Issues Gender Differences Mental Disorder Mental Illness Psychiatry Psychology Psychotherapy Women's Health women's mental health Source Type: blogs

Request for Startups in the Rejuvenation Biotechnology Space, 2020 Edition
This is the latest in a series of yearly posts in which I suggest areas of development for biotech startups I'd like to see actively developed as a part of the longevity industry in the near future. Today, this year, is a good time to be starting a company focused on the production of a novel therapeutic approach to intervening in the aging process. There is a great deal of funding for seed stage investment, and many compelling projects lacking champions, yet to be carried forward from academia into preclinical development. Numerous scientific and industry crossover conferences are now held every year, at which it is possi...
Source: Fight Aging! - February 17, 2020 Category: Research Authors: Reason Tags: Investment Source Type: blogs

Fight Aging! Newsletter, February 17th 2020
Discussion of the Evolutionary Genetics of Aging Thymic Involution Contributes to Immunosenescence and Inflammaging The Potential for Exosome Therapies to Treat Sarcopenia Correlations of Mitochondrial DNA Copy Number and Epigenetic Age Measures Evidence for PASK Deficiency to Reduce the Impact of Aging in Mice The Aging Retina, a Mirror of the Aging Brain Evidence for Loss of Capillary Density to be Important in Heart Disease Aspects of Immune System Aging Proceed More Rapidly in Men Deacetylation of the NLRP3 Inflammasome as a Way to Control Chronic Inflammation Transplantation of Senescent Cells is an ...
Source: Fight Aging! - February 16, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Podcast: Managing Coronavirus Outbreak Anxiety
Does the new coronavirus from China make you a little anxious? How concerned should we be? Is it a real threat or mostly hype? In today’s podcast, Dr. John Grohol, founder and editor-in-chief of PsychCentral.com, explains what the coronavirus is, how it compares to the flu and why it seems to have hit the panic button in a lot of people. He offers tips to avoid getting sick in general, and importantly, gives advice on how to keep our anxiety levels in check when it comes to new disease outbreaks, especially in how we seek information from the media. If you’d like to learn more about the coronavirus and how to deal wi...
Source: World of Psychology - February 13, 2020 Category: Psychiatry & Psychology Authors: The Psych Central Podcast Tags: Anxiety and Panic Disorders General Health-related Interview Podcast The Psych Central Show Source Type: blogs

Burned out on Burnout?
Conclusion Learning how to pay attention to our attention (meta-attention) can be transformative. Using principles from cognitive science, we can create a comprehensive approach (attention capital theory in medicine) to reclaim the meaning and joy that has been depleted from our profession. Increasing the difficulty of our work to match our skill level, delegating low-level tasks to help us focus on critical steps in our physician zone, creating rules to eliminate distractions, and noticing both the wonder and suffering around us may be more important than resilience training or wellness modules. Although well-intention...
Source: The Health Care Blog - February 12, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Burnout physician burnout physician wellness Sanj Katyal Source Type: blogs

Notes on the 2020 Longevity Therapeutics Conference in San Francisco
I recently attended the 2020 Longevity Therapeutics conference in San Francisco. I presented on the work ongoing at Repair Biotechnologies, but as is usually the case the more important parts of the visit took place outside the bounds of the conference proper. Longevity Therapeutics is one of the four or five core conferences for the longevity industry, at which you'll meet many of the early participants - a mix of scientists, entrepreneurs, and investors, and patient advocates. As such, most of the conference goers have already seen my updates, or are otherwise aware of the Repair Biotechnologies programs aimed at thymic ...
Source: Fight Aging! - February 10, 2020 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

When Your Depression Is Perfectly Hidden (Even from Yourself)
Natalie always had a smile on her face, even when discussing painful topics. She was a highly successful, hard worker and an involved, loving mother. In addition to her full-time job as an accountant, Natalie volunteered at her children’s school and in her community. Her house was immaculate. Every item had a place, everything was neatly labeled, and every appliance gleamed. So it was quite a shock to her therapist, Margaret Robinson Rutherford, Ph.D, when she found Natalie lying still in her bed with empty vodka and pill bottles by her side. Rutherford was helping Natalie work through her anxiety over juggling so many r...
Source: World of Psychology - February 10, 2020 Category: Psychiatry & Psychology Authors: Margarita Tartakovsky, M.S. Tags: Books Depression Disorders General Mental Health and Wellness Self-Help Stress Success & Achievement Source Type: blogs

Fight Aging! Newsletter, February 10th 2020
In conclusion, the concept of an epigenetic clock is compelling, but caution should be taken in interpreting associations with age acceleration. Association tests of age acceleration should include age as a covariate. A Discussion of Recent Work on Allotopic Expression of Mitochondrial Genes at the SENS Research Foundation https://www.fightaging.org/archives/2020/02/a-discussion-of-recent-work-on-allotopic-expression-of-mitochondrial-genes-at-the-sens-research-foundation/ A paper published last month outlines recent progress on allotopic expression of mitochondrial genes carried out by the SENS Research ...
Source: Fight Aging! - February 9, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How to Survive a Traumatic Experience
Somewhere in the world people are experiencing traumatic events every day. Communities fall apart due to tornadoes, floods, fires, and war — cataclysmic events that cause multiple losses for everyone in their path. Homes and possessions are lost; individuals suffer injuries; friends and family disappear or die.  Individual events like physical, sexual and/or verbal abuse, illness, abduction, injury or death of loved ones, sudden loss of health, home or job are devastating as well. Traumatic events, whether on a community or personal level, are shocking and life-changing. To feel devastated is normal. To want to sto...
Source: World of Psychology - February 7, 2020 Category: Psychiatry & Psychology Authors: Marie Hartwell-Walker, Ed.D. Tags: Grief and Loss Self-Help Trauma Source Type: blogs

What ’s in a number? Looking at life expectancy in the US
If you were to sum up the overall health of a nation in one single number, what would that be? At the top of the list, you would likely find average life expectancy — the total number of years, on average, that a person in a country can expect to live. Wars, famine, and economic crises are expected to lower life expectancy. Breakthroughs in science, strong economies, and behaviors like eating a healthy diet, exercising, and avoiding tobacco typically raise average life expectancy. An amazing rise, a surprising fall Between 1959 and 2014, the United States experienced an unprecedented increase in life expectancy, which ro...
Source: Harvard Health Blog - February 7, 2020 Category: Consumer Health News Authors: Scott Weiner, MD Tags: Addiction Health Health care disparities Men's Health Women's Health Source Type: blogs

Six Secrets to Healing Your Mind
The first secret to healing your mind is to know that it is actually possible. This shouldn’t be a secret at all, but most people don’t realize their minds can heal. Healing is a word that psychologists rarely use. In fact, the word “healing” isn’t even in the lexicon of our education or training. Instead of healing people, we are taught how to treat conditions, usually targeting specific symptoms or behavioral dysfunctions. But the distinctions between treating and healing are meaningful in terms of their depth and permanence. Though most therapists are not trained to heal, there are models for doing so that are...
Source: World of Psychology - February 6, 2020 Category: Psychiatry & Psychology Authors: Michael R. Kandle, Psy.D. Tags: Personality Psychology Ego Freud id Internal Family Systems Super Ego Source Type: blogs