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Fight Aging! Newsletter, July 25th 2022
This study further demonstrates that AMD is not a single condition or an isolated disease, but is often a signal of systemic malfunction which could benefit from targeted medical evaluation in addition to localized eye care."
Microglia in the Aging Brain, Both Protective and Harmful
https://www.fightaging.org/archives/2022/07/microglia-in-the-aging-brain-both-protective-and-harmful/
A growing body of evidence implicates the changing behavior of microglia in the aging of the brain and onset of neurodegeneration. Microglia are analogous to macrophages, innate immune cells unique to the central nervous syst...
Source: Fight Aging! - July 24, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Weekly Overseas Health IT Links – 23rd July2022.
In this study, researchers sought to determine whether differences in occult hypoxemia treatment existed between people of different races.Occult hypoxemia was defined as arterial blood oxygen saturation of less than 88 percent despite a pulse oximetry reading of 92 percent or more.-----https://healthitsecurity.com/news/security-awareness-and-training-crucial-to-preventing-healthcare-phishing-attacksSecurity Awareness and Training Crucial to Preventing Healthcare Phishing AttacksSecurity awareness and training greatly decreased the likelihood of an employee falling for a healthcare phishing attack, KnowBe4 researchers foun...
Source: Australian Health Information Technology - July 23, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Fight Aging! Newsletter, July 18th 2022
In conclusion, we show that PVS morphology in mice is variable and that the structure and function of pia suggests a previously unrecognized role in regulating CSF transport and amyloid clearance in aging and disease.
Reversing Ovarian Fibrosis in Mice
https://www.fightaging.org/archives/2022/07/reversing-ovarian-fibrosis-in-mice/
Researchers here provide evidence for ovarian fibrosis to be an important mechanism in limiting the age at which female mammals can remain fertile. Interestingly, existing antifibrotic drugs can produce some reversal of this fibrosis, enough to restore ovulation in mice. Fibros...
Source: Fight Aging! - July 17, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
See what happens when the consultant is " Not convinced of STEMI "
Sent by Arjun V, written by Pendell Meyers, edits by SmithA man in his early 40s with history of HTN and obesity suffered sudden out of hospital cardiac arrest. EMS arrived and found him in VF. He was defibrillated successfully, but had several more episodes of VF arrest on the way to the Emergency Department. Here are some examples of his prehospital rhythms:At the ED, sustained ROSC was achieved. He was intubated with minimal available neurologic exam.He had several ECGs recorded in the ED soon after ROSC:The ECGs show likelyAFib with RBBB morphology. There isprofound right axis deviation, which likely r...
Source: Dr. Smith's ECG Blog - July 13, 2022 Category: Cardiology Authors: Pendell Source Type: blogs
That Time ADHD Helped Me Win a Couple of Auctions
The problem with chronic illness is that it's boring. I don't mean for the person stricken in bed and suffering. Who cares about them, right ⸮ I am referring to everybody else who finds the subject duller than a twenty-four hour CSPAN marathon. When the chronically sick try to tell others about their struggles, they are likely to receive no small degree of exasperation from people who can't hide their dismay, as if to say"What? This again?"Of course, not everybody is so callous, and even if they are, they aren't likely to be so open about it. They'll smile at you, nod their head sympathetica...
Source: The Splintered Mind by Douglas Cootey - July 8, 2022 Category: Psychiatry Tags: ADHD Goodreads Journaling Source Type: blogs
Voting Republican is bad for your health
Literally. A study byWarraich HJ, Kumar P, Nasir K, Joynt Maddox KE, and Wadhera RK in BMJfinds this: There has actually been lots of previous research on this general question. As the authors note, " Previous studies have shown that counties that elect Republican candidates tend to experience worse health outcomes, such as fewer gains in life expectancy and increased rates of opioid prescription.56789, " so this is just further confirmation. As they summarize their fndings, " the mortality gap between white residents in Democratic versus Republican counties increased fourfold. Rural Republican count...
Source: Stayin' Alive - June 24, 2022 Category: American Health Source Type: blogs
The New Buzz: These Are The Top Examples Of Digital Therapeutics
Digital Therapeutics or DTx in short is one of the latest buzzwords in the digital health ecosystem. Unlike others (NFT, Metaverse just to name a few) however, we see DTx as a meaningful trend that has the capacity to bring short-term, substantial improvements in personalised healthcare.
What is Digital Therapeutics?
The definition by the Digital Therapeutics Alliance, the main professional hub is:
“Digital therapeutics (DTx) deliver evidence-based therapeutic interventions that are driven by high-quality software programs to prevent, manage, or treat a medical disorder or disease. They are used inde...
Source: The Medical Futurist - June 21, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Digital Health Research Future of Medicine Health Sensors & Trackers Telemedicine & Smartphones software chronic pain apps cancer care mental health DTx digital therapeutics eczema Atopic dermatitis sleep disorders Source Type: blogs
Is this Myo-pericarditis? Or OMI with subsequent pericarditis? Does the angiogram always explain the ECG findings?
Conclusion: Although at 1st glance, it looked like the ECG picture in Figure-1 might be suggestive of acute pericarditis — on further inspection, there are significant ECG features against the diagnosis of acute uncomplicated pericarditis.As per the superb discussion above by Dr. Smith — evolution of this case (including the ECG picture on serial tracings) — are consistent with what probably occurred in today ' s case, namely the combination of acute OMI from LCx occlusion, followed by development of post-infarction regional pericarditis.
Source: Dr. Smith's ECG Blog - June 11, 2022 Category: Cardiology Authors: Steve Smith Source Type: blogs
ST elevation after gunshot to the chest
Conclusion: The ECG in Figure-1 would not be typical for non-traumatic acute pericarditis. However, it could be consistent with traumatic pericarditis (because ECG findings are so variable in traumatic pericarditis).NOTE: The ECG features of acute myocarditis may differ substantially from those of a " pure " pericarditis. There may be a resemblance between these 2 entities — but ST segment deviations (elevation and depression) with myocarditis may not follow the timing seen with pericarditis. In addition, Q waves may develop — so at times it may...
Source: Dr. Smith's ECG Blog - June 8, 2022 Category: Cardiology Authors: Pendell Source Type: blogs
The New Deal and Recovery, Part 18: The Recovery So Far
George Selgin(Although my contributions to this series have so far been more-or-less in their proper order, this one isn ' t: it occurred to me only relatively recently that it would be worthwhile to take stock of the overall progress of the recovery up to the outbreak of the Roosevelt Recession before delving into that episode. Had I done this in the first place, this installment would be Part 10 of the series, with the present Part 10 and all subsequent installments moved up a notch. –Ed.)When it struck down the Agricultural Adjustment Act in January 1936, the Supreme Court dropped the final curtain on the original New...
Source: Cato-at-liberty - June 1, 2022 Category: American Health Authors: George Selgin Source Type: blogs
Fight Aging! Newsletter, May 30th 2022
In conclusion, fisetin supplementation may be a novel strategy to target excess cellular senescence and thereby reduce mitochondrial ROS to improve NO-mediated endothelial function with aging.
Exercise Upregulates BDNF Expression to Promote Dopamine Release and Brain Function
https://www.fightaging.org/archives/2022/05/exercise-upregulates-bdnf-expression-to-promote-dopamine-release-and-brain-function/
Researchers have in the past shown that exercise results in greater amounts of BDNF, which in turn promotes neurogenesis. Here, this line of research is extended to show that exercise results in an increas...
Source: Fight Aging! - May 29, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, May 23rd 2022
In conclusion, remofuscin activates the lysosome-to-nucleus pathway in C. elegans, thereby increasing the expression levels of xenobiotic detoxification genes resulted in extending their lifespan.
Naked Mole-Rat Skin Shows Fewer Signs of Aging
https://www.fightaging.org/archives/2022/05/naked-mole-rat-skin-shows-fewer-signs-of-aging/
Naked mole-rats exhibit a maximum life span that is many times longer than is the case for similarly sized mammals. Further, they are negligibly senescent, showing few age-related declines in function across much of that lengthy life span. That includes maintenance of stem c...
Source: Fight Aging! - May 22, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Wanting a Longer Life Correlates with Achieving a Modestly Longer Life
In conclusion, shorter desired longevity was significantly associated with an increased risk of all-cause mortality, and mortality from cancer and suicide. Lifestyle behaviors particularly mediated this association.
Link: https://doi.org/10.2188/jea.JE20210493
Source: Fight Aging! - May 16, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Top 10 Super-Creepy Medical Technologies
We are all for new technologies here, spending our days researching where the science of medicine goes. With that said, every now and then we see something so creepy that it freaks out even the seasoned team of The Medical Futurist.
So here we collected ten examples of either super creepy medical technologies or ingeniously evil uses of perfectly innocent technologies.
The blood drawing robots
First, this doesn’t really sound creepy. Drawing blood might not be our favourite thing, but nothing of a terror for most of us either. Vein scanners are around for a while, actually being a useful little tool ...
Source: The Medical Futurist - May 3, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Bioethics Cyborgization Robotics Science Fiction Security & Privacy AI dream smartwatch virtual reality blood draw sleep tracking artificial womb gene editing medical robot creepy technologies Source Type: blogs
A man in his 40s who really needs you to understand his ECG
Written by Pendell MeyersA man in his 40s presented for " left sided chest pain sudden onset yesterday when sneezing and coughing that is worsened with inspiration. " He also complained of associated SOB, dizziness, jaw pain, and back pain, which he described as " muscle spasms. " He has also had rhinorrhea and cough for 1 week. Also, left hand numbness today. He went to urgent care for evaluation. An ECG was performed there (unavailable) which reportedly was abnormal, so EMS was called to urgent care to take him to the ED.On EMS arrival, they noted the patient vomited then became unresponsive. He was reportedly...
Source: Dr. Smith's ECG Blog - May 1, 2022 Category: Cardiology Authors: Pendell Source Type: blogs
