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Total 167 results found since Jan 2013.

Podcast: Using Death as Motivation to Live
 How often do you think about death? If you’re like most people, you probably try to keep it in the back corners of your mind. But according to today’s guest, Kate Manser, remembering you might die tomorrow is the best inspiration to live today. Kate asserts that when we incorporate a certain level of mortality awareness into our daily lives, it motivates us to value life so much more and to live each day with intention. We start to find joy in the small things and live in a way that makes a positive outward ripple for all of humanity. So how do we manage to think about death without falling into fear? Tune into to...
Source: World of Psychology - April 2, 2020 Category: Psychiatry & Psychology Authors: The Psych Central Podcast Tags: Death & Dying General Grief and Loss Inspiration & Hope Interview LifeHelper Podcast The Psych Central Show Source Type: blogs

Top Ten Ways I've Survived Social Distancing
Sequestered away and worried about COVID–19? It ’s good to take this crisis seriously, but social distancing doesn’t have to be as dire as people online make it seem. Here are the top ten ways I’ve kept my attitude upbeat while isolated from others.As I’ve written before, I’ve been sick and social distancing since September 2019. I have asthmatic bronchitis, rhinitis, and chronic respiratory inflammation. Consequently, my body has been so busy struggling to breathe, it hasn’t had much oomph left to fight off every cold& virus in Utah. At first, I just thought I was getting a lot of colds f...
Source: The Splintered Mind by Douglas Cootey - March 19, 2020 Category: Psychiatry Tags: Depression Family Goodreads Journaling Source Type: blogs

Top Ten Ways I ' ve Survived Social Distancing
Sequestered away and worried about COVID–19? It ’s good to take this crisis seriously, but social distancing doesn’t have to be as dire as people online make it seem. Here are the top ten ways I’ve kept my attitude upbeat while isolated from others.As I’ve written before, I’ve been sick and social distancing since September 2019. I have asthmatic bronchitis, rhinitis, and chronic respiratory inflammation. Consequently, my body has been so busy struggling to breathe, it hasn’t had much oomph left to fight off every cold& virus in Utah. At first, I just thought I was getting a lot of colds f...
Source: The Splintered Mind by Douglas Cootey - March 19, 2020 Category: Psychiatry Tags: Depression Family Goodreads Journaling Source Type: blogs

Coronavirus FAQ
What is a coronavirus? Coronaviruses are a group of viruses that cause diseases in mammals, including humans, and birds. Why are they called coronaviruses? The name derives from the fact that the viral capsule has a “halo” or “crown” surrounding it. What do coronaviruses do? In humans, the virus infects the airways giving rise to flu-like symptoms, a runny nose, cough, sore throat and fever, these are usually mild, but in rare cases can be lethal. Is there a vaccine against coronaviruses? No. Are there any drugs to block or treat infection? No. When were coronaviruses first discovered? In the 1960s ...
Source: David Bradley Sciencebase - Songs, Snaps, Science - January 24, 2020 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs

Tumor Chip Incorporates Vascular System for More Realistic Drug Testing
Researchers at Kyoto University in Japan have developed a tumor-on-a-chip device that incorporates perfusable blood vessels to more accurately mimic real tumors that occur in the body. The researchers hope that the device will allow for more realisti...
Source: Medgadget - January 7, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Oncology Pathology Source Type: blogs

Fight Aging! Newsletter, December 23rd 2019
In this study, by adenovirus-mediated delivery and inducible transgenic mouse models, we demonstrate the proliferation of both HCs and SCs by combined Notch1 and Myc activation in in vitro and in vivo inner ear adult mouse models. These proliferating mature SCs and HCs maintain their respective identities. Moreover, when presented with HC induction signals, reprogrammed adult SCs transdifferentiate into HC-like cells both in vitro and in vivo. Finally, our data suggest that regenerated HC-like cells likely possess functional transduction channels and are able to form connections with adult auditory neurons. Epige...
Source: Fight Aging! - December 22, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Artificial Intelligence vs. Tuberculosis, Part 1
By SAURABH JHA, MD Slumdog TB No one knows who gave Rahul Roy tuberculosis. Roy’s charmed life as a successful trader involved traveling in his Mercedes C class between his apartment on the plush Nepean Sea Road in South Mumbai and offices in Bombay Stock Exchange. He cared little for Mumbai’s weather. He seldom rolled down his car windows – his ambient atmosphere, optimized for his comfort, rarely changed. Historically TB, or “consumption” as it was known, was a Bohemian malady; the chronic suffering produced a rhapsody which produced fine art. TB was fashionable in Victorian Britain, in part, because c...
Source: The Health Care Blog - December 5, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech Saurabh Jha TB tuberculosis Source Type: blogs

Block an Enzyme, Save a Life
Vern Schramm, professor of biochemistry at Albert Einstein College of Medicine, Bronx, New York. Credit: Albert Einstein College of Medicine. Enzymes drive life. Without them, we couldn’t properly digest food, make brain chemicals, move—or complete myriad other vital tasks. Unfortunately, in certain cases, enzymes also can trigger a host of health problems, including cancer, bacterial infections, and hypertension (high blood pressure). Understanding how enzymes work has been the research focus of Vern Schramm for more than 4 decades. “When we started our work, we were driven not by the desire to find...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - November 26, 2019 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cellular Processes Diseases Precision Medicine Source Type: blogs

Fight Aging! Newsletter, November 18th 2019
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - November 17, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, October 28th 2019
In this study, the enhanced mice live somewhat longer than their unmodified peers, though not as much longer as is the case for the application of telomerase gene therapy. The mice do also exhibit reduced cancer risk, however. The scientists here class telomere shortening as a cause of aging, which is not a point universally agreed upon. Reductions in average telomere length in tissues looks much more like a downstream consequence of reduced stem cell activity than an independent mechanism. Researchers obtain the first mice born with hyper-long telomeres and show that it is possible to extend life without any geneti...
Source: Fight Aging! - October 27, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

20 Medical Technology Advances: Medicine in the Future – Part II.
Nanorobots swimming in blood vessels, in silico clinical trials instead of experimenting with drugs on animals and people, remote brain surgeries with the help of 5G networks – the second part of our shortlist on some astonishing ideas and innovations that could give us a glimpse into the future of medicine is ready for you to digest. Here, we’re going beyond the first part with medical tricorders, the CRISPR/Cas-9 gene-editing method, and other futuristic medical technologies to watch for. 11) In silico clinical trials against testing drugs on animals As technologies transform every aspect of healthcare,...
Source: The Medical Futurist - October 23, 2019 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence E-Patients Future of Medicine Future of Pharma Genomics Health Sensors & Trackers 3d printing AI bioprinting blockchain clinical trials CRISPR digital digital health drug development genetics Innovat Source Type: blogs

Fight Aging! Newsletter, September 23rd 2019
Discussion of Developmental Effects on Aging Microtubule Function and Longevity in Nematodes Quantifying the Correlation Between Poverty and Faster Pace of Aging Matthew O'Connor Presenting on Underdog Pharmaceuticals at Undoing Aging 2019 https://www.fightaging.org/archives/2019/09/matthew-oconnor-presenting-on-underdog-pharmaceuticals-at-undoing-aging-2019/ Here Matthew O'Connor of the SENS Research Foundation talks about the research that led to founding of Underdog Pharmaceuticals, a biotech startup incubated by the foundation to commercialize a means of targeting 7-ketocholesterol in atheroscleros...
Source: Fight Aging! - September 22, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, September 16th 2019
In this study, researchers studied 438,952 participants in the UK Biobank, who had a total of 24,980 major coronary events - defined as the first occurrence of non-fatal heart attack, ischaemic stroke, or death due to coronary heart disease. They used an approach called Mendelian randomisation, which uses naturally occurring genetic differences to randomly divide the participants into groups, mimicking the effects of running a clinical trial. People with genes associated with lower blood pressure, lower LDL cholesterol, and a combination of both were put into different groups, and compared against those without thes...
Source: Fight Aging! - September 15, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Trump ' s Trade Policy So Far: Too Many Trade Wars, Very Little Trade Liberalization
This past week was an eventful one for trade policy, and not in a good way. In the trade world these days, no news is good news, and any tweets are probably bad news. President Trump ’s trade policy has been stridently protectionist, abusive of the constitutional separation of powers, destructive to U.S. alliances, and fundamentally flawed as a strategy to achieve its stated goals.Last week, President Trump was agitated by China ’s retaliatory tariffs (which were in response to tariffs previously imposed by the Trump administration), and in reaction to the Chinese retaliation,Trump announced on Twitter some retaliatio...
Source: Cato-at-liberty - August 27, 2019 Category: American Health Authors: Simon Lester Source Type: blogs

Fight Aging! Newsletter, August 19th 2019
In conclusion, our data show how oncogenic and tumor-suppressive drivers of cellular senescence act to regulate surveillance processes that can be circumvented to enable SnCs to elude immune recognition but can be reversed by cell surface-targeted interventions to purge the SnCs that persist in vitro and in patients. Since eliminating SnCs can prevent tumor progression, delay the onset of degenerative diseases, and restore fitness; since NKG2D-Ls are not widely expressed in healthy human tissues and NKG2D-L shedding is an evasion mechanism also employed by tumor cells; and since increasing numbers of B cells express NKG2D ...
Source: Fight Aging! - August 18, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs