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Jim Mellon Interviewed by Adam Ford at Undoing Aging 2019
Adam Ford of Science, Technology, and the Future carried out a number of interviews while at Undoing Aging in Berlin earlier this year. The interview materials are steadily being processed and uploaded, and that just recently included this interview with Jim Mellon, billionaire investor and philanthropist, cofounder of Juvenescence, and a very down to earth fellow who is interested in improving the human condition by targeting aging with new biotechnologies. Accordingly, he has used his resources to put himself into a position to talk up the longevity industry, move research forward, and attract a great deal more funding f...
Source: Fight Aging! - August 12, 2019 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Localising “ Angina related artery ” ( ARA ) in UA/NSTEMI : Can we differentiate culprit artery from lesion ?
Identifying the culprit after a criminal event may be easy for the police.For cadiologists investigating the crime scne after a coronary event, It is a different story. (Of course, localization of IRA after a STEMI may not be really difficult.) But , when a patient is having UA and coronary artery shows multiple lesions, we do have real diagnostic issue. The general dictum could be tightest lesion or complex eccentric lesions with thrombus is likely to be the culprit. This has important therapeutic Impication as we are argued to address the active lesions first. The following study was done in 2009 trying to address ...
Source: Dr.S.Venkatesan MD - August 11, 2019 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs
Fight Aging! Newsletter, August 12th 2019
We examined 9293 individuals from the Copenhagen General Population Study using nuclear magnetic resonance spectroscopy measurements of total cholesterol, free- and esterified cholesterol, triglycerides, phospholipids, and particle concentration. Fourteen subclasses of decreasing size and their lipid constituents were analysed: six subclasses were very low-density lipoprotein (VLDL), one intermediate-density lipoprotein (IDL), three low-density lipoprotein (LDL), and four subclasses were high-density lipoprotein (HDL). Remnant lipoproteins were VLDL and IDL combined.
Mean nonfasting cholesterol concentration was 72...
Source: Fight Aging! - August 11, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Virtual Bodies For Real Drugs: In Silico Clinical Trials Are The Future
Traditional clinical trials are equivalent of billions of dollars and years of hard work with no guarantee for the new drug to be approved by regulatory bodies, not to speak about the dangers of testing medication on animals and/or humans. What if we could take a radical turn? What if we conducted clinical trials on virtual bodies that could perfectly mimic human physiology? With the help of artificial intelligence, enhanced computer simulations, and advances in personalized medicine, in silico trials might be a reality in the coming years.
The magic expression is in
silico
As technologies transform every aspect of h...
Source: The Medical Futurist - August 10, 2019 Category: Information Technology Authors: nora Tags: Future of Medicine Future of Pharma Personalized Medicine AI artificial intelligence clinical clinical trial clinical trials digital drug drugs in silico in silico trials Innovation medication simulation virtual Source Type: blogs
The Present Popularity of Epigenetic Reprogramming to Treat Aging
A fair number of research groups are presently working on ways to force large numbers of cells in the body to adopt more youthful epigenetic profiles. Much of this research is an outgrowth of the discovery of induced pluripotency, the ability to reprogram any cell into a pluripotent stem cell that is largely indistinguishable from an embryonic stem cell, capable of generating any of the cell types in the body. This process also happens to reset many of the epigenetic markers of age that are found in cells in old tissues, alongside restoring mitochondrial function by clearing out damaged mitochondria, and a few other intere...
Source: Fight Aging! - August 9, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Device Speeds Cervical Cancer Screening
When screening for cervical cancer, immunofluorescence staining is used to identify the presence of proteins that are biomarkers for the disease. It is a slow and meticulous process that requires lab technicians to prepare individual cells for analys...
Source: Medgadget - August 6, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Diagnostics Ob/Gyn Oncology Source Type: blogs
Why Don ’t Digital Health Investors Finance Solutions To Tough Medical Issues?
Why did activity trackers flood the digital health market, while there’s barely a company dealing with menopause, arthritis, or rare diseases? How do digital health investors decide when it comes to funding a new project, and what are the specific factors to take into account in relation to the healthcare market? We looked around what could scare off financiers from funding tough medical issues, and have a suggestion on how to bring forward solutions for marginalized health problems. Read on.
Investment in digital health for everyone?
Investment in healthcare, especially in the digital
health market, is growing ste...
Source: The Medical Futurist - August 3, 2019 Category: Information Technology Authors: nora Tags: Business Future of Medicine companies company digital digital health digital health startups finance funding Healthcare investment technology Source Type: blogs
Why Don ’t Digital Health Investors Finance Tough Medical Issues?
Why did activity trackers flood the digital health market, while there’s barely a company dealing with menopause, arthritis, or rare diseases? How do digital health investors decide when it comes to funding a new project, and what are the specific factors to take into account in relation to the healthcare market? We looked around what could scare off financiers from funding tough medical issues, and have a suggestion on how to bring forward solutions for marginalized health problems. Read on.
Investment in digital health for everyone?
Investment in healthcare, especially in the digital
health market, is growing ste...
Source: The Medical Futurist - August 3, 2019 Category: Information Technology Authors: nora Tags: Business Future of Medicine companies company digital digital health digital health startups finance funding Healthcare investment technology Source Type: blogs
The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
July 4, 2019 Edition.-----Well it looks like the world has survived the G20 meeting in Osaka with Trump and Xi agreeing to start working again on a trade agreement and a few concessions from both sides to calm and smooth the way. What happens with the Koreas will be interesting, but thus far it looks like a fizzer. July 4 with tanks is a bit of a change and many Americans are not impressed. Trump's damage to the global economy is a real worry and now South Korea / Japan are fighting the 1940's war about "comfort women" yet again. More damage to world trade..Brexit continues to be an absolute swamp!Mr Morrison has had a goo...
Source: Australian Health Information Technology - July 3, 2019 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
From Chernobyl To Mars: The Future Of Radiation Protection
In the minutes after block 4 of the nuclear power
plant in Chernobyl exploded, no one knew that they are experiencing a disaster
that never happened anywhere before on planet Earth. The public health,
environmental, and even the socio-political consequences were disastrous and we
can still experience the negative impacts. That’s why we posed the question of
what public health authorities, as well as individuals, can do to mitigate the
consequences of radiation exposure, and what digital technologies are available
for radiation detection. In this respect, after our investigations, it even
turned out that it would be benef...
Source: The Medical Futurist - June 29, 2019 Category: Information Technology Authors: nora Tags: Future of Medicine Space Medicine astronautics chernobyl disaster fiction Health Healthcare Innovation mars nuclear power plant public health radiation radiation exposure radiation protection technology Source Type: blogs
Decades-Long Surveys Suggest The “Deleterious Effects of Smoking May Extend to Detrimental Personality Changes”
By Christian Jarrett
There is increasing recognition that while our personality traits are stable enough to shape our lives profoundly, they are also partly malleable, so that our choices and experiences can feedback and influence the kind of people we become. A new study in the Journal of Research in Personality shines a light on a highly consequential behaviour that captures this dynamic – smoking cigarettes.
The results add “… to existing knowledge on the implications of smoking by showing that this behaviour is also likely to alter individuals’ characteristic ways of thinking, feeling, and behaving ...
Source: BPS RESEARCH DIGEST - June 21, 2019 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Health Personality Source Type: blogs
Fight Aging! Newsletter, June 3rd 2019
In conclusion, there is solid evidence that obesity deregulates cellular mechanisms related to nutrient sensing.
Altered Intercellular Communication
It is accepted that aging impacts the organism at the cellular level, but also decreases the capacity of cells of an organism to interact. During aging, there is a decreased communication at the neuronal, neuroendocrine, and endocrine levels. Two of the most compelling examples of impaired communication are inflammaging and immunosenescence. The inflammaging phenotype results in elevated cytokines. These cytokines can accelerate and propagate the aging process. T...
Source: Fight Aging! - June 2, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Werner Syndrome versus Natural Aging
In science, a model is a system that is close enough to reality that one can learn something useful from it. It is almost always cost-effective to use models rather than the real thing as a test bed, even if the differences sometimes lead to misleading results. Medical and life science researchers put a great deal of effort into producing animal models of human diseases, a way to explore causes and treatments within available budgets. In some cases this is just a matter of standardization, as a given condition with very similar mechanisms exists in multiple species besides our own. In others, such as Alzheimer's disease, t...
Source: Fight Aging! - May 27, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, May 27th 2019
In this study, we found that cofilin competes with tau for direct microtubule binding in vitro, in cells, and in vivo, which inhibits tau-induced microtubule assembly. Genetic reduction of cofilin mitigates tauopathy and synaptic defects in Tau-P301S mice and movement deficits in tau transgenic C. elegans. The pathogenic effects of cofilin are selectively mediated by activated cofilin, as active but not inactive cofilin selectively interacts with tubulin, destabilizes microtubules, and promotes tauopathy. These results therefore indicate that activated cofilin plays an essential intermediary role in neurotoxic signaling th...
Source: Fight Aging! - May 26, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
5G In Healthcare: Boosting Remote Brain Surgeries, Connected Health, Or Medical VR
The next telecommunication revolution is just around the corner: the promises of high bandwidth, low latency and low-power-low-cost of 5G will open the gate to a flood of new inventions and the implementation of ideas, which are already long in the public consciousness – such as stable augmented reality or truly immersive virtual reality platforms powered by networks. 5G in healthcare will finally allow the building of infrastructure suitable for the interplay of health sensors, algorithms, and smart devices, for the smooth operation of telemedicine, or even for providing a way for parents to interact with babies who are...
Source: The Medical Futurist - May 4, 2019 Category: Information Technology Authors: nora Tags: Future of Medicine Telemedicine & Smartphones 5G connected digital Innovation IoT medical medical technology mobile mobile health Surgery telecom telecommunication telehealth telesurgery Source Type: blogs
