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Making Oncology Accessible in Nepal
By SAURABH JHA, MD
In this episode of Radiology Firing Line Podcast, I speak with Bishal Gyawali MD, PhD. Dr. Gyawali obtained his medical degree from Kathmandu. He received a scholarship to pursue a PhD in Japan. Dr. Gyawali’s work focuses on getting cheap and effective treatment to under developed parts of the world. Dr. Gyawali is an advocate for evidence-based medicine. He has published extensively in many high impact journals. He coined the term “cancer groundshot.” He was a research fellow at PORTAL. He is currently a scientist at the Queen’s University Cancer Research Institute in Kingston...
Source: The Health Care Blog - April 23, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Radiology Firing Line Podcasts RogueRad @roguerad Bishal Gyawali nepal Oncology Saurabh Jha Source Type: blogs
Why Is the USA Only the 35th Healthiest Country in the World?
By ETIENNE DEFFARGES
According the 2019 Bloomberg Healthiest Country Index, the U.S. ranks 35th out of 169 countries. Even though we are the 11th wealthiest country in the world, we are behind pretty much all developed economies in terms of health. In the Americas, not just Canada (16th) but also Cuba (30th), Chile and Costa Rica (tied for 33rd) rank ahead of us in this Bloomberg study.
To answer this layered question, we need to look at the top ranked countries in the Bloomberg Index: From first to 12th, they are Spain; Italy; Iceland; Japan; Switzerland; Sweden; Australia; Singapore; Norway; Israel; Luxe...
Source: The Health Care Blog - April 15, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Economics Health disparities Health Policy American healthcare Etienne Deffarges Mediterranean Diet Opioids world health Source Type: blogs
The Most Pressing Issues In Bioethics
Who owns medical and genetic data? How to regulate gene editing? Where is the boundary of enhancing physical or cognitive human capabilities? What to do with biological differences widening the gap of the haves and have-nots? Could we define where is the boundary to augment life? Will we sue robots or algorithms for medical malpractice? With the constant advancement of technology, unprecedented moral, ethical and legal concerns are surfacing. Channeling them into substantial debates will get us closer to their fair solution step by step. Here, we collected the most pressing issues in bioethics.
Bioethicists
of the world...
Source: The Medical Futurist - March 26, 2019 Category: Information Technology Authors: nora Tags: Bioethics Cyborgization Genomics bioethical data debate DNA future gene editing genetic genetics Innovation legal longevity medical medical data moral sex sexuality technology Source Type: blogs
Fight Aging! Newsletter, March 18th 2019
This study provides a possible reason why genes carrying health risks have persisted in human populations. The second found evidence for multiple variants in genes related to ageing that exhibited antagonistic pleiotropic effects. They found higher risk allele frequencies with large effect sizes for late-onset diseases (relative to early-onset diseases) and an excess of variants with antagonistic effects expressed through early and late life diseases.
There also exists other recent tangible evidence of antagonistic pleiotropy in specific human genes. The SPATA31 gene has been found under strong positive genomic sele...
Source: Fight Aging! - March 17, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, March 11th 2019
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - March 10, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Medicinal Mushrooms: Turkey Tail (Trametes versicolor), Reishi (Ganoderma lucidum) and Lion's mane (Hericium erinaceus)
There some evidence in PubMed than medicinal mushrooms may play a role in treatment of some cancers. Most of the claims of medical benefits are bot backed up by high quality studies as of 2019. References are below.---What is turkey tail?Turkey tail is a type of mushroom that grows on dead logs worldwide. It's named turkey tail because its rings of brown and tan look like the tail feathers of a turkey. Its scientific name is Trametes versicolor or Coriolus versicolor. In traditional Chinese medicine, it is known as Yun Zhi. In Japan, it is known as kawaratake (roof tile fungus). Turkey tail has been used in traditional Chi...
Source: Clinical Cases and Images - Blog - February 13, 2019 Category: Universities & Medical Training Tags: Medicinal Mushrooms Oncology Source Type: blogs
Third International Conference on End of Life Law, Ethics, Policy, and Practice
Here is the program for the Third International Conference on End of Life Law, Ethics, Policy, and Practice. Pretty awesome.
Thursday 7 March, 2019
08.30-09.00Registration & Welcome Coffee
09.00-09.10Welcome by the Chair of the Scientific Committee – Kenneth Chambaere (BE)
09.10-09.30Introduction by an external speaker (TBC)
Plenary 1: Latest developments in assisted dying around the world
09.30-10.00Developments in European countries – Agnes van der Heide (NL)
10.00-10.30Recent developments and the future of MAiD in Canada – Jocelyn Downie (CAN)
10.30-11.00A review of developmen...
Source: blog.bioethics.net - January 18, 2019 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care syndicated Source Type: blogs
A Randomized Controlled Trial for Fan Therapy in Dyspnea
by Bob Arnold (@rabob)Winter suits me just fine since I do not like heat. I have a lot of sympathy for patients with chronic obstructive lung disease who do not have an air conditioner during the summer. I am told that there is nothing worse than sitting in hot, humid weather and not being able to breathe.As a palliative care physician, I love fans. When my patients are short of breath and opiates do not work (1,2) I send their families down to the local ACE hardware store to buy a hand-held fan. Therefore, I was excited tosee an article in the Journal of Pain and Symptom Management on fan therapy being effective in treati...
Source: Pallimed: A Hospice and Palliative Medicine Blog - January 11, 2019 Category: Palliative Care Tags: arnold dyspnea journal article JPSM Source Type: blogs
Exceptional longevity: why some people live to be more than 100-year old
Interventions that promote longevity, remembered by mnemonic:DEEP purple - “eat colorful plant foods:Dietary modification,Exercise, activeEngagement,Purposeful living (click here toenlarge the image).Based on a Mayo Clinic Proceedings article (https://www.mayoclinicproceedings.org/article/S0025-6196(18)30792-4/):Exceptional Human Longevity: the oldest old have an extreme phenotype of delayed onset of age-related diseases and/or resistance to lethal illnesses occurring earlier in life.Centenarians have delayed onset of chronic diseasesDuring the span of human history the likelihood of living from birth to age 100 rose fro...
Source: Clinical Cases and Images - Blog - December 25, 2018 Category: Universities & Medical Training Tags: Lifestyle Longevity Mayo Clinic Source Type: blogs
Last Month in Oncology with Dr. Bishal Gyawali: November 2018
By BISHAL GYAWALI MD
Keynote speech
There was a very sobering piece in NEJM by the FDA last month in which the authors try to explore what went wrong with the Keynote-183, Keynote-185 and checkmate 602 trials testing PD-1 inhibitors combinations with pomalidomide or lenalidomide and dexamethasone in multiple myeloma. Interim analysis of Keynote 183 and 185 revealed detrimental effects on overall survival (OS) with hazard ratios of 1.61 and 2.06, not explained by differences in toxicities alone. The checkmate 602 trial was also halted in light of these findings and also showed higher mortality in the nivolumab combina...
Source: The Health Care Blog - December 17, 2018 Category: Consumer Health News Authors: matthew holt Tags: Pharmaceuticals Physicians Bishal Gyawali Cancer drugs cancer immunotherapy Clinical Trials FDA Oncology PD-1 inhibitors Source Type: blogs
Designer Babies: A Dystopian Sidetrack of Gene Editing
A Chinese scientist shocked the scientific community a couple of days ago with the announcement of having modified the very blueprint of life. If his claims are true, he tried to bestow two baby girls the ability to resist possible future infections with HIV. The outrage shows that humanity is not prepared to utilize the power of gene editing on embryos yet. We have no idea about the biological consequences, and we haven’t tackled the necessary legal and ethical issues.
Genes to become toys of the “Gods”?
Humanity has come a long way since Aldous Huxley pinned down how methods of genetic engineering, biological cond...
Source: The Medical Futurist - December 15, 2018 Category: Information Technology Authors: nora Tags: Bioethics Future of Medicine Genomics designer babies designer baby Gene gene editing genes Genome genome sequencing Health Healthcare healthcare system Innovation technology Source Type: blogs
The Power of Mobile Health
2018 was a very busy year, requiring extensive international travel —I racked up more than 400,000 miles this fall. But now that my schedule is a bit more manageable, I plan to start posting again to “Life as a Healthcare CIO”. In addition to my travels to China, Japan, Australia and a long list of other countries, I managed to find the time to work with my esteemed co-author Paul Cerrato on our third book, The Transformative Power of Mobile Medicine. We wanted to share the Preface with readers and have included it below, along with a link to Elsevier ’s web site for those interested in reading the entire boo...
Source: Life as a Healthcare CIO - December 14, 2018 Category: Information Technology Source Type: blogs
Fight Aging! Newsletter, December 10th 2018
In conclusion, this is the first report to show that pyroptotic cell death occurs in the aging brain and that the inflammasome can be a viable target to decrease the oxidative stress that occurs as a result of aging.
Reducing Levels of Protein Manufacture Slows Measures of Aging in Nematodes
https://www.fightaging.org/archives/2018/12/reducing-levels-of-protein-manufacture-slows-measures-of-aging-in-nematodes/
Researchers here demonstrate that an antibiotic slows aging in nematode worms, providing evidence for it to work through a reduction in protein synthesis. Beyond a slowing of aging, one of the con...
Source: Fight Aging! - December 9, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Current State of Therapeutic Development Involving Induced Pluripotent Stem Cells
A little more than a decade has passed since the development of a simple cell reprogramming approach that reliably created pluripotent stem cells from ordinary somatic cells, known as induced pluripotent stem cells. These stem cells are very similar, near identical in fact, to the embryonic stem cells that were previously the only reliable source of cells capable of forming any cell type in the body. Arguably the most important aspect of induced pluripotency is not the promise of the ability to generate patient-matched cells for regenerative therapies and tissue engineering of replacement organs, but rather that it is a lo...
Source: Fight Aging! - December 4, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Can Money Buy You Longevity And Health?
Better treatment options, dietary conditions and (perhaps) less stress could make the life of the rich also healthier. However, when it comes to longevity and aging, do they really have better chances? Can the upper 0.1 percent secure their health for long decades or even reverse the process of growing old? Could society somehow also benefit from the quest of the richest for longevity?
Are health and longevity on the shopping list?
You can have an awful lot of things with money. For a starter, you can buy ice cream or Nutella, which are synonymous to self-love, so the Beatles was only partly right in singing that you can...
Source: The Medical Futurist - November 22, 2018 Category: Information Technology Authors: nora Tags: Bioethics Cyborgization Future of Medicine Medical Professionals Patients Policy Makers age aging aging research blood eternal life genetics immortality Innovation life sciences longevity silicon valley stem cell Source Type: blogs
