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Total 3278 results found since Jan 2013.

First Experiences with peripheral Nerve Stimulation using an implantable System as a Treatment Method for the Complex Regional Pain Syndrome CRPS 2
CONCLUSION: Peripheral nerve stimulation appears to be a suitable therapy option for the treatment of CRPS 2 when conservative and conventional surgical treatment methods have failed. The experience with our patients shows that neuropathic pain could be successfully reduced by an average of about 4 points on the NRS. Arthrogenous symptoms, on the other hand, were not influenced by the PNS. Since CRPS is a psychosomatic illness, the integration of PNS into a multimodal therapy concept with physiotherapy and occupational therapy and psychology is essential for the success of the treatment.PMID:35318620 | DOI:10.1055/a-1687-9374
Source: Handchirurgie Mikrochirurgie Plastische Chirurgie - March 23, 2022 Category: Cosmetic Surgery Authors: Isabelle Sawetz Christian Smolle Werner Girsch Source Type: research

Diagnosis and outcomes of 225 consecutive cases of crps of the hand
CONCLUSIONS: . Unlike CRPS, all patients in this series had a true, diagnosable condition explaining their clinical picture. Most patients who accepted to be operated had a favorable outcome.PMID:36952596 | DOI:10.1097/PRS.0000000000010454
Source: Hand Surgery - March 23, 2023 Category: Surgery Authors: Francisco Del Pi ñal Source Type: research

Use of a Medication Quantification Scale for Comparison of Pain Medication Usage in Patients with Complex Regional Pain Syndrome (CRPS)
ConclusionsThere appears to be only a weak correlation between amount of pain medication prescribed and patients' reported subjective pain intensity within this limited patient population. The Medication Quantification Scale is a viable tool for the analysis of pharmaceutical treatment of CRPS patients and would be useful in further prospective studies of pain medication prescription practices in the CRPS population worldwide.
Source: Pain Medicine - September 15, 2014 Category: Anesthesiology Authors: Michael A. Gallizzi, Ravand S. Khazai, Christine M. Gagnon, Stephen Bruehl, R. Norman Harden Tags: Original Article Source Type: research

Pathological mechanism of musculoskeletal manifestations associated with CRPS type II: An animal study
We examined functional, biochemical, and histological alterations in affected parts, including contiguous zones, using an animal model. Ten-week-old male Wistar rats were assigned to 5 groups: a normal group receiving no treatment, a sham operation group with surgical exploration, an immobilization group with surgical exploration plus internal knee joint immobilization, a surgical neuropathy group prepared by spinal nerve ligation (SNL) of the left L5 nerve root, and a surgical neuropathy+immobilization group with simultaneous SNL and knee joint immobilization. Mechanical allodynia and knee contracture were compared betwee...
Source: Pain - July 11, 2014 Category: Anesthesiology Authors: Hideyuki Ota, Tetsuya Arai, Katsuyuki Iwatsuki, Hideki Urano, Toshikazu Kurahashi, Shuichi Kato, Michiro Yamamoto, Hitoshi Hirata Tags: Research papers Source Type: research

Rapid treatment-induced brain changes in pediatric CRPS
Abstract To date, brain structure and function changes in children with complex regional pain syndrome (CRPS) as a result of disease and treatment remain unknown. Here, we investigated (a) gray matter (GM) differences between patients with CRPS and healthy controls and (b) GM and functional connectivity (FC) changes in patients following intensive interdisciplinary psychophysical pain treatment. Twenty-three patients (13 females, 9 males; average age ± SD = 13.3 ± 2.5 years) and 21 healthy sex- and age-matched controls underwent magnetic resonance imaging. Compared to controls, patients had reduced GM in ...
Source: Anatomy and Embryology - December 17, 2014 Category: Anatomy Source Type: research

0P24. T cells and anti-inflammatory interleukins in skin biopsies of Complex Regional Pain Syndrome (CRPS)
CRPS (Complex regional Pain Syndrome) is a neuropathic pain syndrome occurring after trauma. It is associated with increased posttraumatic inflammation. Patients show inflammatory signs like increased skin temperature, edema, hyperhidrosis, and hypertrichosis. In CRPS blood samples pro-inflammatory cytokines were increased and anti-inflammatory cytokines reduced. We found in skin biopsies an increase of pro-inflammatory cytokines (TNF-α, Il-6) and mast cells. The aim of this study was the quantification of T cells and the immunohistochemical staining of anti-inflammatory interleukins and of Interferon-γ (IFN- in the skin of CRPS patients.
Source: Clinical Neurophysiology - July 5, 2015 Category: Neuroscience Authors: T. Schlereth, S. Bolz, N. Albrecht, F. Birklein Source Type: research

(218) Characterization of patients with complex regional pain syndrome (CRPS) in a tertiary care pain management setting: A Collaborative Health Outcomes Information Registry (CHOIR) study
Given that CRPS is a relatively rare disease, there is a need for better characterization of patients with this condition. The current study examined the physical, psychological and social characteristics of patients with CRPS in a tertiary care pain management setting. Our sample consisted of 150 patients diagnosed with CRPS type 1 or 2, from Stanford Pain Management Center, between the years of 2012 and 2015. Patients were identified using ICD9 billing codes associated with their clinic visit and their diagnoses were subsequently verified by chart review.
Source: The Journal of Pain - March 31, 2016 Category: Materials Science Authors: M. Adelus, J. Sturgeon, T. Rico, V. Tawfik, S. Mackey Tags: B03 Complex Regional Pain Syndrome Source Type: research

(118) Physical and psychological predictors of dysfunction in complex regional pain syndrome (CRPS): a Collaborative Health Outcomes Information Registry (CHOIR) study
There remains a relative dearth of studies examining meaningful predictors of physical function and pain interference in individuals with CRPS. The current study investigated predictors of pain-related dysfunction in patients with CRPS in a tertiary care pain management setting. Our sample consisted of 150 patients diagnosed with CRPS type 1 or 2, who reported outcomes at Stanford Pain Management Center, between the years of 2012 and 2015. Patients were identified using ICD9 codes associated with their clinic visit and their diagnosis was subsequently verified by chart review.
Source: The Journal of Pain - March 31, 2016 Category: Materials Science Authors: M. Adelus, J. Sturgeon, T. Rico, V. Tawfik, S. Mackey Source Type: research

Kinesiophobia modulates the feedforward motor control of the affected limb in complex regional pain syndrome (CRPS): a single-case study. Revised title: Fear of movement modulates the feedforward motor control of the affected limb in complex regional pain syndrome (CRPS): a single-case study
Pain-related fear can exacerbate physical disability and pathological pain in complex regional pain syndrome (CRPS) patients. We conducted a kinematic analysis of grasping movements with a pediatric patient suffering from CRPS in an upper limb to investigate how pain-related fear affects motor control. Using a three-dimensional measurement system, we recorded the patient ’s movement while grasping three vertical bars of different diameters (thin, middle, thick) with the affected and intact hands.
Source: Medical Hypotheses - December 2, 2017 Category: Biomedical Science Authors: Michihiro Osumi, Masahiko Sumitani, Yuko Otake, Shu Morioka Source Type: research

Signs and Symptoms in 1043 Patients with Complex Regional Pain Syndrome (CRPS)
• CRPS was caused by just 11 distinct etiological triggers in 99.5% of our patients.• Some diagnostic signs were found only in about 50% of patients.• A weighted screening score aids in distinguishing CRPS from other pain disorders.• Descriptions of pain quality in CRPS might be quite charac teristic.
Source: The Journal of Pain - February 2, 2018 Category: Materials Science Authors: Stephan Ott, Christian Maih öfner Tags: Original Report Source Type: research

Complex regional pain syndrome (CRPS) : An update.
Abstract The acute phase of complex regional pain syndrome (CRPS) is pathophysiologically characterized by an activation of the immune system and its associated inflammatory response. During the course of CRPS, central nervous symptoms like mechanical hyperalgesia, loss of sensation, and body perception disorders develop. Psychological factors such as pain-related anxiety and traumatic events might have a negative effect on the treatment outcome. While the visible inflammatory symptoms improve, the pain often persists. A stage adapted, targeted treatment could improve the prognosis. Effective multidisciplinary t...
Source: Schmerz - April 17, 2018 Category: Anesthesiology Authors: Dimova V, Birklein F Tags: Schmerz Source Type: research

P54. Differences in neuronal representation of mental rotation in CRPS patients and healthy controls
Spatial integration of the body matrix, especially representation of the affected side is reduced in patients suffering from complex regional pain syndrome (CRPS; Moseley et al., 2009). The parietal sulcus integrates multimodal sensory input to spatial aspects of the own body and is therefore essential for processing mental rotation (MR) (Lebon et al., 2012). Since the training of MR has turned out to be among the effective therapy strategies for CRPS (Graded motor imagery; GMI; Moseley et al., 2006), MR is also important for the pathophysiological understanding of CRPS.
Source: Clinical Neurophysiology - July 10, 2018 Category: Neuroscience Authors: M. Kohler, S. Strau ß, U. Horn, T. Usichenko, I. Langner, M. Domin, M. Lotze Source Type: research

Operative therapy of chronic palmar luxation of the distal ulna in florid CRPS - two cases.
We present two cases of chronic palmar luxation of the distal ulna which entails the development of complex regional pain syndrome (CRPS). Both cases have been finally treated with a hemiresection-interposition-arthroplasty of the distal radioulnar joint with perioperatively applied regional nerve block and i. v. administration of vitamin c. After surgical intervention function has improved and the CRPS symptomes subsided rapidly after few weeks. PMID: 30045371 [PubMed - in process]
Source: Handchirurgie Mikrochirurgie Plastische Chirurgie - July 26, 2018 Category: Cosmetic Surgery Tags: Handchir Mikrochir Plast Chir Source Type: research