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Fusing Engineering And Mathematical Principles Helps Create Dynamic Brain Models
Models of the human brain, patterned on engineering control theory, may some day help researchers control such neurological diseases as epilepsy, Parkinson's and migraines, according to a Penn State researcher who is using mathematical models of neuron networks from which more complex brain models emerge. "The dual concepts of observability and controlability have been considered one of the most important developments in mathematics of the 20th century," said Steven J. Schiff, the Brush Chair Professor of Engineering and director of the Penn State Center for Neural Engineering...
Source: Health News from Medical News Today - February 22, 2013 Category: Consumer Health News Tags: Epilepsy Source Type: news

Engineering control theory helps create dynamic brain models
(Penn State) Models of the human brain, patterned on engineering control theory, may some day help researchers control such neurological diseases as epilepsy, Parkinson's and migraines, according to a Penn State researcher who is using mathematical models of neuron networks from which more complex brain models emerge.
Source: EurekAlert! - Medicine and Health - February 19, 2013 Category: Global & Universal Source Type: news

Efficacy of MAP0004 in Treating Severe Migraine Pain (P01.082)
CONCLUSIONS: This analysis indicates that MAP0004 was effective in the acute treatment of severe migraine pain in the Phase 3 clinical trial.Supported by: MAP Pharmaceuticals, Inc.Disclosure: Dr. Kori has received personal compensation for activities with MAP Pharmaceuticals, Inc. Dr. Kori holds stock and/or stock options in MAP Pharmaceuticals, Inc. Dr. Kori has received research support from MAP Pharmaceuticals, Inc. Dr. Connors has received personal compensation for activities with MAP Pharmaceuticals. Dr. Zhou has received personal compensation for activities with MAP Pharmaceuticals, Inc as an employee. Dr. Lu is an e...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Kori, S., Connors, E., Zhou, J., Lu, B., Borland, S. Tags: P01 Headache: Clinical Presentation and Therapeutics Source Type: research

Consistency of Migraine Pain Relief after Repeated Administration of MAP0004 (P01.086)
CONCLUSIONS: In this post-hoc analysis, MAP0004 provided consistent migraine pain relief for the 1st, 5th, 15th or the 25th QM assessed over approximately one year.Supported by: MAP Pharmaceuticals, Inc.Disclosure: Dr. Kori has received personal compensation for activities with MAP Pharmaceuticals, Inc. Dr. Kori holds stock and/or stock options in MAP Pharmaceuticals, Inc. Dr. Kori has received research support from MAP Pharmaceuticals, Inc. Dr. Lu is an employee of MAP Pharmaceuticals. Dr. Connors has received personal compensation for activities with MAP Pharmaceuticals. Dr. Li has received personal compensation for acti...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Kori, S., Lu, B., Connors, E., Li, X., Kellerman, D. Tags: P01 Headache: Clinical Presentation and Therapeutics Source Type: research

Use of ACEI in Migraine Prophylaxis: Why We Don't Look Back? (P01.092)
CONCLUSIONS: ACEI have a lower profile of side effects compared to other blood pressure medications currently used in migraine prophylaxis. The benefits with ACEI recognized in the management of congestive heart failure, hypertension associated with diabetes and secondary stroke prevention maybe can be extrapolated to a younger population. Early initiation of an ACEI in patients with migraine attacks can possibly reduce the incidence of stroke in a population at a higher risk of it later in life.Disclosure: Dr. Delgado has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Delgado, A. Tags: P01 Headache: Clinical Presentation and Therapeutics Source Type: research

A Novel Mutation in the Mitochondrial DNA Cytochrome B Gene (MTCYB) in a Patient with Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke like Episodes Syndrome (P02.088)
CONCLUSIONS: This case demonstrates that MTCYB must be included in the already long list of mitochondrial DNA genes that have been associated with the MELAS phenotype.Supported by: Grant from the National Institutes of Health (HD32062) and by the Marriott Mitochondrial Disorder Clinical Research Fund (MMDCRF). PGR is supported by a postdoctoral fellowship from Ministerio de Educacion y Ciencia, Spain.Disclosure: Dr. Emmanuele has nothing to disclose. Dr. Sotiriou has nothing to disclose. Dr. Gutierrez Rios has nothing to disclose. Dr. Ganesh has nothing to disclose. Dr. Ichord has nothing to disclose. Dr. Foley has nothing...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Emmanuele, V., Sotiriou, E., Gutierrez Rios, P., Ganesh, J., Ichord, R., Foley, A. R., Akman, O., DiMauro, S. Tags: P02 Child Neurology I Source Type: research

Ictal Vasoconstriction of the Left Middle Cerebral Artery on Magnetic Resonance Angiography in Pediatric Confusional Migraine: A Case Series of Five Patients (P02.098)
CONCLUSIONS: Our cases demonstrate vasoconstriction in the L MCA territory during a confusional migraine. Vasoconstriction has also been described in some case reports of hemiplegic migraines, lending further credence to the relationship between hemiplegic and confusional migraines. These cases reinforce the role of neurovascular changes in the pathophysiology of migraines.Disclosure: Dr. Spencer has nothing to disclose. Dr. Schomer has nothing to disclose. Dr. Minster has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Spencer, K., Schomer, M., Minster, A. Tags: P02 Child Neurology I Source Type: research

A Pediatric Case of Reversible Cerebral Vasoconstriction Syndrome: Complexity of Diagnosis Amidst Co-Morbid Anxiety and Depression (P02.099)
CONCLUSIONS: RCVS has only rarely been reported in children and only once in a girl. Our case highlights the importance of considering RCVS when a child presents with severe sudden headache, even in the setting of chronic headaches. With the increased use in children of medications such as triptans and SSRIs, which are risk factors for RCVS, the incidence of RCVS in this population may also rise.Disclosure: Dr. Segal has nothing to disclose. Dr. Bain has nothing to disclose. Dr. Amin has nothing to disclose. Dr. Monoky has nothing to disclose. Dr. Thompson has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Segal, D., Bain, J., Amin, R., Monoky, D., Thompson, S. Tags: P02 Child Neurology I Source Type: research

SMART Syndrome (Stroke-Like Migraine Attacks after Radiation Therapy) in Adult and Pediatric Patients (P03.007)
CONCLUSIONS: SMART syndrome appears to be a reversible and recurrent long term complication of cranial irradiation. A review of the data indicates that age and gender may play a role in the development of the disease. Additionally, we postulate other mechanisms of SMART syndrome including possible genetic and hormonal influences.Disclosure: Dr. Armstrong has nothing to disclose. Dr. DiMario has received personal compensation for activities with E-Pocrates.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Armstrong, A., DiMario, F. Tags: P03 Child Neurology II Source Type: research

Low Dose Lacosamide-Induced Atrial Fibrillation: Case Analysis with Literature Review (P03.135)
CONCLUSIONS: Low dose LCM may provoke atrial fibrillation in at risk patients. Neurologists and internists need to be cognizant of this potential adverse effect. Cardiac monitoring may be required with LCM dose rapid titration, especially if given intravenously.Disclosure: Dr. Velez has nothing to disclose. Dr. Kaufman has nothing to disclose. Dr. Wong has nothing to disclose. Dr. Mani has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Velez, A., Kaufman, K., Wong, S., Mani, R. Tags: P03 Epilepsy: Comorbidities and Cardiovascular Risk Source Type: research

Effectiveness of Standardized Combination Therapy for Migraine Treatment in the Pediatric Emergency Department
ConclusionStandardized combination therapy is effective for acute pediatric migraine therapy in the ED by significantly reducing headache pain scores, length of ED stay, and hospital admission rates.
Source: Headache: The Journal of Head and Face Pain - February 13, 2013 Category: Neurology Authors: Stephanie Leung, Blake Bulloch, Christine Young, Marcy Yonker, Mark Hostetler Tags: Research Submission Source Type: research

Effectiveness of Standardized Combination Therapy for Migraine Treatment in the Pediatric Emergency Department.
CONCLUSION: Standardized combination therapy is effective for acute pediatric migraine therapy in the ED by significantly reducing headache pain scores, length of ED stay, and hospital admission rates. PMID: 23406529 [PubMed - as supplied by publisher]
Source: Headache - February 13, 2013 Category: Neurology Authors: Leung S, Bulloch B, Young C, Yonker M, Hostetler M Tags: Headache Source Type: research

Nerve Stimulation Cuts Down on Migraines (CME/CE)
(MedPage Today) -- A noninvasive device that electrically stimulates the trigeminal nerve prevented migraines for patients whose episodes were not well controlled by medication alone, a trial showed.
Source: MedPage Today Neurology - February 11, 2013 Category: Neurology Source Type: news

Effective Drug-Free Treatment For Migraine (Cefaly®)
The American scientific journal NEUROLOGY publishes the positive results of the PREMICE clinical study on the effectiveness and safety of the CEFALY(R) medical device in the prevention of migraine. NEUROLOGY (official journal of the American Academy of Neurology, the number one among the most-cited journals worldwide in the field of neurology) is publishing the results of the multi-centre PREMICE clinical study (PREvention of MIgraine with CEfaly(R)). The results show the effectiveness of Cefaly(R) in the reduction of migraines...
Source: Health News from Medical News Today - February 11, 2013 Category: Consumer Health News Tags: Headache / Migraine Source Type: news

Nerve Stimulator May Provide Effective Drug-Free Migraine Treatment
A nerve stimulator could be a promising new form of treatment for migraine sufferers, suggests a recent study published in in the journal Neurology. Results from a clinical study of Cefaly(R) appear to indicate that electrical stimulation of the supraorbital nerve using a stimulator device placed on the forehead is extremely effective at helping prevent the onset of a migraine. Migraines are characterized as being a form of moderate to severe recurrent headaches - lasting for hours or even days - that cause excessive throbbing pain, nausea and extreme sensitivity to light...
Source: Health News from Medical News Today - February 11, 2013 Category: Consumer Health News Tags: Headache / Migraine Source Type: news

Nerve Stimulator New Form Of Migraine Treatment
A nerve stimulator may be a new form of migraine treatment. Electrical stimulation of the supraorbital nerve using a stimulator device placed on one's forehead is extremely effective at helping prevent migraines, according to a recent study published in in the journal Neurology. Migraines are characterized as being a form of moderate to severe recurrent headaches - lasting for hours or even days - that cause excessive throbbing pain, nausea and extreme sensitivity to light. The World Health Organization estimates that around 10% of adults worldwide suffer from migraine...
Source: Health News from Medical News Today - February 11, 2013 Category: Consumer Health News Tags: Headache / Migraine Source Type: news

'Star Trek' headband for migraine shows promise
Conclusion While this news may seem like something out of science fiction, it appears that there is indeed some cause to think that a device looking similar to that worn by Star Trek’s Geordi La Forge (pictured above) could have the potential to be used by people who have migraines. This news story is based on a well-designed study that benefits from using identical STS and sham devices. It also benefits from having a high follow-up rate and the fact that neither participants nor investigators were aware of which treatment each person used. The study demonstrates that the STS had some effect in improving the main outcom...
Source: NHS News Feed - February 8, 2013 Category: Consumer Health News Tags: Medical practice Neurology Source Type: news

Could this 'Star Trek' headband help banish migraines?
A study from Liege University in Belgium found the band, worn across the forehead for 20 minutes a day, reduced the debilitating attacks by a third.
Source: the Mail online | Health - February 7, 2013 Category: Consumer Health News Source Type: news

Zapping Migraines
Source: HealthDay - Related MedlinePlus Page: Migraine
Source: MedlinePlus Health News - February 7, 2013 Category: Consumer Health News Source Type: news

Nerve-Stimulating Device Might Ease Migraines
Title: Nerve-Stimulating Device Might Ease MigrainesCategory: Health NewsCreated: 2/6/2013 4:35:00 PMLast Editorial Review: 2/7/2013 12:00:00 AM
Source: MedicineNet Migraine General - February 7, 2013 Category: Neurology Source Type: news

Nerve stimulation may help some with migraines
NEW YORK (Reuters Health) - A nerve stimulator placed on the forehead may help prevent migraines among some people who get the headaches regularly - and it appears to be safe, according to a new trial.
Source: Reuters: Health - February 6, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Nerve Stimulation May Help Some with Migraines
A nerve stimulator placed on the forehead may help prevent migraines among some people who get the headaches regularly - and it appears to be safe, according to a new trial.Source: Reuters Health Related MedlinePlus Page: Migraine
Source: MedlinePlus Health News - February 6, 2013 Category: Consumer Health News Source Type: news

Placebo as good as most drugs for kids' migraines
NEW YORK (Reuters Health) - A drug-free placebo pill prevents migraines in kids and teens just as well as most headache medicines, according to a new review of past evidence.
Source: Reuters: Health - January 28, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Placebo as Good as Most Drugs for Kids' Migraines
A drug-free placebo pill prevents migraines in kids and teens just as well as most headache medicines, according to a new review of past evidence.Source: Reuters Health Related MedlinePlus Pages: Medicines and Children, Migraine
Source: MedlinePlus Health News - January 28, 2013 Category: Consumer Health News Source Type: news

Really?: The Claim: Bright Light and Exercise Trigger Migraines
A study published in the journal Neurology found that unlike exercise, bright light may not be a cause of migraines. But more research is needed.
Source: NYT Health - January 28, 2013 Category: Consumer Health News Authors: By ANAHAD O'CONNOR Tags: Really? migraine Headaches Body Exercise Featured Migraine Headaches Source Type: news

Understanding Migraine Headaches
Learn what triggers your migraines and how to treat them.
Source: U.S. News - Health - January 28, 2013 Category: Consumer Health News Source Type: news

Lightning Linked To Some Headaches, Migraines
University of Cincinnati (UC) researchers have found that lightning may affect the onset of headache and migraines. These results, published in the online edition of the journal Cephalalgia, are the first tying lightning to headache and could help chronic sufferers more efficiently anticipate headache and migraine arrival and begin preventive treatment immediately...
Source: Health News from Medical News Today - January 28, 2013 Category: Consumer Health News Tags: Headache / Migraine Source Type: news

Migraines carry serious social stigma, study finds
Patients with chronic migraines suffer from as much social stigma as people with epilepsy, according to a study conducted by researchers from Thomas Jefferson University Hospital, Rutgers University and published in the journal PLOS ONE. Social stigma refers to people...
Source: NaturalNews.com - January 28, 2013 Category: Consumer Health Advice Source Type: news

Lightning may affect headache, migraines
CINCINNATI, Jan. 27 (UPI) -- Lightning may have "its own unique effect" on the onset of headaches and migraines, researchers at the University of Cincinnati suggest.
Source: Health News - UPI.com - January 27, 2013 Category: Consumer Health News Source Type: news

Nearby lightning may be linked to migraines
NEW YORK (Reuters Health) - Weather has long been considered one of many potential migraine triggers, but a new study links lightning, specifically, to the onset of the severe headaches that plague more than 28 million Americans.
Source: Reuters: Health - January 25, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Nearby Lightning May Be Linked to Migraines
Weather has long been considered one of many potential migraine triggers, but a new study links lightning, specifically, to the onset of the severe headaches that plague more than 28 million Americans.Source: Reuters Health Related MedlinePlus Page: Migraine
Source: MedlinePlus Health News - January 25, 2013 Category: Consumer Health News Source Type: news

Video: Migraine studies challenge usual "trigger" theory
Dr. Joshua Cohen, a neurologist at New York's Headache Institute at St. Luke's-Roosevelt Hospital, talks to Charlie Rose and Norah O'Donnell about a pair of new studies that seek to answer the mystery behind the cause of migraines.
Source: Health News: CBSNews.com - January 25, 2013 Category: Consumer Health News Source Type: news

Lightning may cause 'thunderous headaches'
Conclusion This study finds that the people in these two trials were around a third more likely to report a headache or migraine on a day when there was lightning. Migraines can be triggered by different things in different people, including food, drink, stress, exercise or other activities. Some people do report that environmental or weather factors can have an effect on their headaches. Therefore, lightning as a possible trigger for headache or migraine in some sufferers is certainly plausible. However, the findings do not prove that lightning is the direct cause of the headaches of people in this study. Importantly, th...
Source: NHS News Feed - January 25, 2013 Category: Consumer Health News Tags: Lifestyle/exercise Neurology Source Type: news

Could Lightning Spur Headaches and Migraines?
Title: Could Lightning Spur Headaches and Migraines?Category: Health NewsCreated: 1/25/2013 10:35:00 AMLast Editorial Review: 1/25/2013 12:00:00 AM
Source: MedicineNet Migraine General - January 25, 2013 Category: Neurology Source Type: news

Lightning linked to onset of headache, migraines
Researchers have found that lightning may affect the onset of headaches and migraines.
Source: ScienceDaily Headlines - January 24, 2013 Category: Science Source Type: news

Migraine "triggers" may not cause migraines after all
Lights or exercise, which many believe may bring on migraine episodes, were shown only to do so in 11 percent of cases
Source: Health News: CBSNews.com - January 24, 2013 Category: Consumer Health News Source Type: news

Migraine Triggers May Not Always Trigger Migraines
Title: Migraine Triggers May Not Always Trigger MigrainesCategory: Health NewsCreated: 1/24/2013 2:12:00 PMLast Editorial Review: 1/24/2013 2:12:07 PM
Source: MedicineNet Migraine General - January 24, 2013 Category: Neurology Source Type: news

Research ties lightning to onset of headache, migraines
(University of Cincinnati Academic Health Center) University of Cincinnati researchers have found that lightning may affect the onset of headaches and migraines.
Source: EurekAlert! - Medicine and Health - January 24, 2013 Category: Global & Universal Source Type: news

Allergen to buy Map Pharmaceuticals for $958M
Allergan Inc. has agreed to buy Mountain View's Map Pharmaceuticals for $958 million, propelled by the expected Food and Drug Administration approval of Map's inhaled treatment for migraines. Allergan will snap up Map shares for $25 per share, a 60 percent premium. A treatment for migraines that was a joint project for the two companies, Levadex, is up for approval by the FDA no later than April 15. Check out Ron Leuty's story in our sister publication, the San Francisco Business Times, for the…
Source: bizjournals.com Health Care:Biotechnology headlines - January 23, 2013 Category: Biotechnology Authors: Jon Xavier Source Type: research

Right target, but missing the bulls-eye for Alzheimer's
Alzheimer's disease is the most common cause of late-life dementia. The disorder is thought to be caused by a protein known as amyloid-beta, or Abeta, which clumps together in the brain, forming plaques that are thought to destroy neurons. This destruction starts early, too, and can presage clinical signs of the disease by up to 20 years. For decades now, researchers have been trying, with limited success, to develop drugs that prevent this clumping. Such drugs require a "target" — a structure they can bind to, thereby preventing the toxic actions of Abeta. Now, a new study out of UCLA suggests tha...
Source: UCLA Newsroom: Health Sciences - January 23, 2013 Category: Universities & Medical Training Source Type: news

Migraine Triggers May Not Always Trigger Migraines
Worrying about what may trigger a migraine attack adds to the discomfort of many people with migraines. But according to a new study from Denmark, much of that worry may be unfounded.
Source: WebMD Health - January 23, 2013 Category: Consumer Health News Source Type: news

Study Questions Importance of 'Triggers' in Setting Off Migraines
In research involving patients with migraine with aura, just 1 in 10 reacted to typical triggers Source: HealthDay Related MedlinePlus Page: Migraine
Source: MedlinePlus Health News - January 23, 2013 Category: Consumer Health News Source Type: news

Common Triggers Rarely Provoke Migraines in Small Study
Source: Physician's First Watch current issue - January 23, 2013 Category: Primary Care Tags: Medical News Source Type: news

Allergan aims to widen migraine treatment with MAP Pharma buy
(Reuters) - U.S. specialty drugmaker Allergan Inc said late on Tuesday that it would buy MAP Pharmaceuticals Inc for about $958 million in cash, an acquisition intended to widen its presence in the treatment of adult migraines.
Source: Reuters: Health - January 22, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Mother saves son's life after Googling revealed he could have a BRAIN TUMOUR not simply 'migraines'
Sabina Jones, from Shrewsbury, said she pleaded with doctors to give her 12-year-old son Kian a CT scan, which revealed the cancer.
Source: the Mail online | Health - January 22, 2013 Category: Consumer Health News Source Type: news

FDA Approves 1st Skin Patch to Combat Migraines
Title: FDA Approves 1st Skin Patch to Combat MigrainesCategory: Health NewsCreated: 1/21/2013 4:36:00 PMLast Editorial Review: 1/22/2013 12:00:00 AM
Source: MedicineNet Migraine General - January 22, 2013 Category: Neurology Source Type: news

When seeing auras can augur ill
People who suffer migraines with aura are thought to be at a higher risk of stroke, finds Glenda Cooper
Source: Telegraph Health - January 21, 2013 Category: Consumer Health News Source Type: news

Skin Patch For Migraines Receives FDA Approval
The FDA has approved Zecuity (sumatriptan iontophoretic transdermal system) for the treatment of acute migraine in adults with or without aura. Zecuity is a battery-powered skin patch that delivers sumatriptan through the patient's skin - it is a single-use medication. Sumatriptan is the most extensively prescribed migraine drug. According to NuPathe Inc., the makers and marketers of Zecuity, the patch is effective in treating migraine headache pain as well as migraine-related nausea...
Source: Health News from Medical News Today - January 20, 2013 Category: Consumer Health News Tags: Headache / Migraine Source Type: news

Are Migraines Dangerous?
I have had migraines for years. While my headaches are less frequent and less severe than they once were, I have heard that they put me at greater risk of dementia when I get older. Is this true?
Source: Dr. Weil Q and A - January 18, 2013 Category: Consumer Health Advice Source Type: news