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Cancer: Gastric (Stomach) Cancer
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Total 20369 results found since Jan 2013.
A modified esophagogastric reconstruction method after laparoscopic proximal gastrectomy: A technical note with video vignette
CONCLUSION: The "arch-bridge-type" reconstruction method is safe and time saving. It has advantages in simplifying the procedure of conventional double flap technique and reducing postoperative complications after proximal gastrectomy.PMID:37730505 | DOI:10.1016/j.asjsur.2023.09.017
Source: Asian Journal of Surgery - September 20, 2023 Category: Surgery Authors: Yinkui Wang Bailong Li Fei Shan Shuangxi Li Kan Xue Rulin Miao Ziyu Li Source Type: research
TRPM8 as a Potential Biomarker and Therapeutic Target for Gastric Cancer Identified by a Combination of Text Mining and RNA Sequencing
CONCLUSION: This study provides insights into the underlying role of TRPM8 in cell proliferation. In addition, TRPM8 may be used as a potential therapeutic target for patients with gastric cancer.PMID:37728085 | DOI:10.2174/1566523223666230529142423
Source: Current Gene Therapy - September 20, 2023 Category: Genetics & Stem Cells Authors: Na Kong Wendong Li Jun Zhang Xin Wang Lin Hu Qiqi Xu Source Type: research
Comparison of proximal gastrectomy with double-flap technique and double-tract reconstruction for proximal early gastric cancer: a meta-analysis
AbstractSurgical resection is the main treatment for proximal gastric cancer, but there is no consensus on its reconstruction. We carried out a meta-analysis to evaluate the effects of double-tract reconstruction (DTR) and double-flap technique (DFT) on postoperative quality of life in patients with proximal gastric cancer. Systematic searches of PubMed, Web of Science, EBSCO, and the Cochrane Library were performed. Literature for the last 5 years was searched without language restrictions. The cutoff date for the search was 12 April 2023. Literature and research searches were conducted independently by two researchers ...
Source: Updates in Surgery - September 20, 2023 Category: Surgery Source Type: research
Clinical implication of CDH1 mutations in genetic testing for diffuse gastric cancer patients
CONCLUSIONS: We conclude that germline CDH1 genetic testing is indicated only in families meeting the clinical criteria for the HDGC syndrome. This observation suggests that clinical phenotypes that do not clearly fulfill these criteria should not be considered for CDH1 genetic testing.PMID:37725907 | DOI:10.1159/000533774
Source: Oncology - September 19, 2023 Category: Cancer & Oncology Authors: Giovanni Corso Cristina Maria Trovato Salvatore Petitto Antonia Girardi Alessandra Margherita De Scalzi Beatrice Bianchi Francesca Magnoni Antonio Cioffi Viviana Galimberti Paolo Veronesi Giovanni Mazzarol Patrick Maisonneuve Source Type: research
Vegetarian diets and the risk of gastrointestinal cancers: a meta-analysis of observational studies
CONCLUSION: Adhering to vegetarian diets reduces the risk of gastrointestinal tumorigenesis. More data from well-conducted cohort and other studies are needed.PMID:37724454 | DOI:10.1097/MEG.0000000000002643
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Tongtong Bai Juanjuan Peng Xinqi Zhu Chengyu Wu Source Type: research
Harnessing role of sesamol and its nanoformulations against neurodegenerative diseases
Biomed Pharmacother. 2023 Sep 17;167:115512. doi: 10.1016/j.biopha.2023.115512. Online ahead of print.ABSTRACTSesamol is a lignan of sesame seeds and a natural phenolic molecule that has emerged as a useful medical agent. Sesamol is a non-toxic phytoconstituent, which exerts certain valuable effects in the management of cancer, diabetes, cardiovascular diseases, neurodegenerative diseases (NDs), etc. Sesamol is known to depict its neuroprotective role by various mechanisms, such as metabolic regulators, action on oxidative stress, neuroinflammation, etc. However, its poor oral bioavailability, rapid excretion (as conjugate...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 19, 2023 Category: Drugs & Pharmacology Authors: Navneet Singh Sukriti Vishwas Amandeep Kaur Harmanpreet Kaur Violina Kakoty Rubiya Khursheed M V N L Chaitanya Molakpogu Ravindra Babu Ankit Awasthi Leander Corrie Vancha Harish Palakurthi Yanadaiah Saurabh Gupta Amany A Sayed Amr El-Sayed Iftikhar Ali Os Source Type: research
YY1 is regulated by ALKBH5-mediated m6A modification and promotes autophagy and cancer progression through targeting ATG4B
This study aimed to assess the essential transcription factors (TFs) involved in autophagy regulation in GC. Western blot, RFP-GFP-LC3 double fluorescence and transmission electron microscopy (TEM) assays were used to probe autophagy activity in GC cells. Methylated RNA immunoprecipitation (MeRIP) was utilized to evaluate the ALKBH5-regulated m6A levels of YY1. Gain- and loss-of-function assays were employed in the scrutiny of the biological effects of the ALKBH5/YY1/ATG4B axis on cancer cell proliferation and invasion abilities in vitro. Per the findings, YY1 was identified as a crucial transcriptional activator of cancer...
Source: Aging - September 19, 2023 Category: Biomedical Science Authors: Shijiang Wang Jiangbo Nie Kaiying Xu Yangyang Liu Weilai Tong Anan Li Wei Zuo Zhili Liu Feng Yang Source Type: research
Clinical implication of CDH1 mutations in genetic testing for diffuse gastric cancer patients
CONCLUSIONS: We conclude that germline CDH1 genetic testing is indicated only in families meeting the clinical criteria for the HDGC syndrome. This observation suggests that clinical phenotypes that do not clearly fulfill these criteria should not be considered for CDH1 genetic testing.PMID:37725907 | DOI:10.1159/000533774
Source: Oncology - September 19, 2023 Category: Cancer & Oncology Authors: Giovanni Corso Cristina Maria Trovato Salvatore Petitto Antonia Girardi Alessandra Margherita De Scalzi Beatrice Bianchi Francesca Magnoni Antonio Cioffi Viviana Galimberti Paolo Veronesi Giovanni Mazzarol Patrick Maisonneuve Source Type: research
YY1 is regulated by ALKBH5-mediated m6A modification and promotes autophagy and cancer progression through targeting ATG4B
This study aimed to assess the essential transcription factors (TFs) involved in autophagy regulation in GC. Western blot, RFP-GFP-LC3 double fluorescence and transmission electron microscopy (TEM) assays were used to probe autophagy activity in GC cells. Methylated RNA immunoprecipitation (MeRIP) was utilized to evaluate the ALKBH5-regulated m6A levels of YY1. Gain- and loss-of-function assays were employed in the scrutiny of the biological effects of the ALKBH5/YY1/ATG4B axis on cancer cell proliferation and invasion abilities in vitro. Per the findings, YY1 was identified as a crucial transcriptional activator of cancer...
Source: Aging - September 19, 2023 Category: Biomedical Science Authors: Shijiang Wang Jiangbo Nie Kaiying Xu Yangyang Liu Weilai Tong Anan Li Wei Zuo Zhili Liu Feng Yang Source Type: research
Effects of methylation and imprinting expression of Insulin-like growth factor 2 gene in gastric cancer
CONCLUSION: Our data suggest that IGF2 is involved in the occurrence and development of gastric cancer. Targeting IGF2 may be a potential therapeutic target for gastric cancer.PMID:37718779 | DOI:10.3233/CBM-230105
Source: Cancer Biomarkers : Section A of Disease Markers - September 18, 2023 Category: Cancer & Oncology Authors: Jiting Sun Jun Shu Duo Shi Wen Liu Yan Zhang Bing Luo Source Type: research
Clinical outcomes of conversion surgery following immune checkpoint inhibitors and chemotherapy in stage IV gastric cancer
CONCLUSIONS: Conversion surgery holds the potential for significant survival benefits in stage IV GC patients who have achieved a favorable clinical response to immunochemotherapy. Individuals with signet ring cell carcinoma may experience increased post-conversion surgery recurrence.PMID:37720943 | DOI:10.1097/JS9.0000000000000738
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Huayuan Liang Xiao Yan Xinhua Chen Zhiwei Li Yaopeng Qiu Fengping Li Minghao Wang Zhicheng Huang Kaihua Huang Qing Xie Huimin Zhang Guoxin Li Hao Liu Liying Zhao Source Type: research
Reduced risk of de novo Barrett esophagus after bariatric surgery: a national database study
CONCLUSION: Patients who underwent bariatric surgery (RYGB or SG) had a lower risk of being diagnosed with BE compared with screening colonoscopy controls who did not receive bariatric surgery. This effect appears to be largely mediated by reduction in weight and BMI.PMID:37722939 | DOI:10.1016/j.soard.2023.08.009
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - September 18, 2023 Category: Surgery Authors: Alexander Hurtado Apoorva K Chandar Jaime Abraham Perez Regina Casselberry Scott A Martin Kayla DeLano Mujjahid Abbas Amitabh Chak Source Type: research
Corrigendum to: "Dihydroartemisinin inhibits the growth and invasion of gastric cancer cells by regulating cyclin D1-CDK4-Rb signaling" Pathol. Res. Pract. 216 (2020) 152795
Pathol Res Pract. 2023 Sep 16:154824. doi: 10.1016/j.prp.2023.154824. Online ahead of print.NO ABSTRACTPMID:37722992 | DOI:10.1016/j.prp.2023.154824
Source: Pathology, Research and Practice - September 18, 2023 Category: Pathology Authors: Hui-Ning Fan Mei-Ying Zhu Shi-Qiao Peng Jin-Shui Zhu Jing Zhang Guo-Qiang Qu Source Type: research
Crocin Combined With Cisplatin Regulates Proliferation, Apoptosis And Emt Of Gastric Cancer Cells Via The Fgfr3/Mapk/Erk Pathway In Vitro And In Vivo
CONCLUSION: Our results showed that up-regulation of FGFR3 reversed the inhibitory effect of crocin+DDP on the MAPK/ERK signaling pathway. Still, this effect could be counteracted by PD184352, which simultaneously regulated the proliferation, apoptosis, and EMT of AGS cells. In conclusion, crocin, combined with DDP, inhibits proliferation, apoptosis, and EMT of GC through the FRFR3/MAPK/ERK pathway.PMID:37718528 | DOI:10.2174/1568009624666230915111239
Source: Current Cancer Drug Targets - September 18, 2023 Category: Cancer & Oncology Authors: Yan Li Qi-Jing Guo Rong Chen LingLin Zhao Xianshu Cui Yingfang Deng Yu-Shuang Luo Source Type: research
