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Bone-Targeted Therapy Regimen and Skeletal-Related Events in Patients Surviving Longer Than 2 Years With Metastatic Breast Cancer and Bone Metastasis
CONCLUSION: Oncologists may have increased flexibility regarding the frequency of administration of BTT along with their choice of agent. Our study showed no significant difference in the prevention of overall SRE or development of BTT-associated harms between the BTT regimens evaluated.PMID:37735019 | DOI:10.1016/j.clbc.2023.08.008
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Athira Jayan Akshara Singareeka Raghavendra Roland Bassett Carlos H Barcenas Source Type: research
Prepectoral Direct-To-Implant One-Stage Reconstruction With ADMs: Safety and Outcome in "Thin Patients"
CONCLUSIONS: Prepectoral reconstruction with ADM in thin patients may be considered as safe as in standard BMI patients. Rippling may be more frequent, but, whenever needed, easy to correct with a few sessions of lipo-grafts.LEVEL OF EVIDENCE: III.PMID:37735018 | DOI:10.1016/j.clbc.2023.08.007
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Anna Scarabosio Filippo Contessi Negrini Gaetano Pisano Yvonne Beorchia Luigi Castriotta Francesco De Francesco Michele Riccio Pier Camillo Parodi Nicola Zingaretti Source Type: research
Value of ultrasound in assessing response to neoadjuvant chemotherapy in breast cancer
CONCLUSION: This study has shown significance in reducing LD measurements on ultrasound as a predictor of PCR and RCB class. This adds weight to the current practice of using ultrasound at the start, mid and end of chemotherapy cycles to monitor NACT responses.PMID:37734976 | DOI:10.1016/j.crad.2023.07.010
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: H F Lim A Sharma C Gallagher P Hall Source Type: research
Differential benefit of metronomic chemotherapy among triple negative breast cancer subtypes treated in the IBCSG Trial 22-00
CONCLUSIONS: Our results show a differential benefit of low-dose CM therapy across different TNBC subtypes. Low-dose CM therapy could be considered as a potential immunomodulatory strategy for TNBC tumors with IM subtype in the early-disease setting.PMID:37733800 | DOI:10.1158/1078-0432.CCR-23-1267
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Andrea Joaquin Garcia Mattia Rediti David Venet Samira Majjaj Roswitha Kammler Elisabetta Munzone Lorenzo Gianni Beat Th ürlimann Istv án Láng Marco Colleoni Sherene Loi Giuseppe Viale Meredith M Regan Laurence Buisseret Fran çoise Rothé Christos Sot Source Type: research
Near-infrared spectral tomography for predicting residual cancer burden during early stage neoadjuvant chemotherapy for breast cancer
CONCLUSION: NIRST holds promise as a potential clinical tool that can be seamlessly integrated into existing clinical workflow within the infusion suite. By providing early assessment of RCB, NIRST has potential to improve breast cancer patient management strategies.PMID:37733788 | DOI:10.1158/1078-0432.CCR-23-1593
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Xu Cao Kristen E Muller Mary D Chamberlin Jiang Gui Peter A Kaufman Gary N Schwartz Roberta M DiFlorio-Alexander Brian W Pogue Keith D Paulsen Shudong Jiang Source Type: research
Identification of a TRP channel-related risk model for predicting prognosis and therapeutic effects of patients with hepatocellular carcinoma
CONCLUSIONS: We successfully established a highly accurate prognostic model for predicting overall survival and therapeutic effects using TRP channel-related genes.PMID:37733242 | DOI:10.1007/s00432-023-05394-7
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Chong Pang Zhe Xu Jilong Han Fujun Li Hongyan Zhu Jiaqi Zhang Dong Wang Xundi Xu Source Type: research
Traumatic sigmoid colon rupture due to breast cancer metastasis: a case report
Clin J Gastroenterol. 2023 Sep 21. doi: 10.1007/s12328-023-01859-x. Online ahead of print.ABSTRACTThe metastasis of breast cancer to the gastrointestinal tract is rare. Herein, we presented the case of an 85-year-old woman who had a history of invasive lobular carcinoma and experienced complete colon rupture due to relatively low-energy trauma. The patient underwent bilateral total mastectomy and axillary dissection following preoperative chemotherapy 6 years ago. She had a local recurrence 2 years after the surgery and underwent chemotherapy. Subsequently, the cancer metastasized to the thoracolumbar area and retroperiton...
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Tomonori Yoshida Munenori Ide Kazuhisa Katayama Mitsuhiro Yanai Ryo Kurosaki Hisashi Shimizu Kazuhisa Arakawa Tatsuya Miyazaki Hiroshi Saeki Ken Shirabe Source Type: research
Left epigastric isolated tumor fed by the inferior phrenic artery diagnosed as ectopic hepatocellular carcinoma: A case report
CONCLUSION: This asymptomatic ectopic HCC case described achieved an excellent result due to early detection, radical resection, and systematic surveillance.PMID:37731571 | PMC:PMC10507550 | DOI:10.12998/wjcc.v11.i26.6231
Source: Clinical Lung Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Hong-Bo Liu Li-Hua Zhao Yong-Jian Zhang Zhi-Feng Li Lei Li Qian-Peng Huang Source Type: research
Albendazole induces an anti-tumor effect and potentiates PD-L1 blockade immunotherapy
CONCLUSION: ABZ inhibits melanoma growth and metastasis. Moreover, ABZ synergized with PD-L1 blockade mediates tumor regression.PMID:37730912 | DOI:10.1007/s00432-023-05415-5
Source: Clinical Lung Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Weinan Zhang Zhiqiang He Fucheng Liang Jie Gong Liuchang Tan Juan Yang Siji Song Luoyingzi Xie Yuangang Lu Source Type: research
Patient-doctor interactions around alternative and complementary medicine in the context of oncology care in a Latin American country
CONCLUSIONS: The low frequency of communication contrasts to the increasing use of CAM. Divergent perspectives between doctors and patients could limit shared decision-making on the use of CAM. Enhanced knowledge and education on CAM for both actors is fundamental to improve their interaction and to move away from paternalistic and confrontational communication, particularly in a world region with cultural backgrounds that influence the use of CAM.PMID:37734425 | DOI:10.1016/j.ctim.2023.102986
Source: Complementary Therapies in Medicine - September 21, 2023 Category: Complementary Medicine Authors: Pilar Garc ía-Padilla Dennys Garc ía-Padilla Maria Fernanda Ram írez-Castro Paula Pulido-Rinc ón Ra úl Murillo Source Type: research
Bone-Targeted Therapy Regimen and Skeletal-Related Events in Patients Surviving Longer Than 2 Years With Metastatic Breast Cancer and Bone Metastasis
CONCLUSION: Oncologists may have increased flexibility regarding the frequency of administration of BTT along with their choice of agent. Our study showed no significant difference in the prevention of overall SRE or development of BTT-associated harms between the BTT regimens evaluated.PMID:37735019 | DOI:10.1016/j.clbc.2023.08.008
Source: Clinical Genitourinary Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Athira Jayan Akshara Singareeka Raghavendra Roland Bassett Carlos H Barcenas Source Type: research
Prepectoral Direct-To-Implant One-Stage Reconstruction With ADMs: Safety and Outcome in "Thin Patients"
CONCLUSIONS: Prepectoral reconstruction with ADM in thin patients may be considered as safe as in standard BMI patients. Rippling may be more frequent, but, whenever needed, easy to correct with a few sessions of lipo-grafts.LEVEL OF EVIDENCE: III.PMID:37735018 | DOI:10.1016/j.clbc.2023.08.007
Source: Clinical Genitourinary Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Anna Scarabosio Filippo Contessi Negrini Gaetano Pisano Yvonne Beorchia Luigi Castriotta Francesco De Francesco Michele Riccio Pier Camillo Parodi Nicola Zingaretti Source Type: research
Value of ultrasound in assessing response to neoadjuvant chemotherapy in breast cancer
CONCLUSION: This study has shown significance in reducing LD measurements on ultrasound as a predictor of PCR and RCB class. This adds weight to the current practice of using ultrasound at the start, mid and end of chemotherapy cycles to monitor NACT responses.PMID:37734976 | DOI:10.1016/j.crad.2023.07.010
Source: Clinical Genitourinary Cancer - September 21, 2023 Category: Cancer & Oncology Authors: H F Lim A Sharma C Gallagher P Hall Source Type: research
Differential benefit of metronomic chemotherapy among triple negative breast cancer subtypes treated in the IBCSG Trial 22-00
CONCLUSIONS: Our results show a differential benefit of low-dose CM therapy across different TNBC subtypes. Low-dose CM therapy could be considered as a potential immunomodulatory strategy for TNBC tumors with IM subtype in the early-disease setting.PMID:37733800 | DOI:10.1158/1078-0432.CCR-23-1267
Source: Clinical Genitourinary Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Andrea Joaquin Garcia Mattia Rediti David Venet Samira Majjaj Roswitha Kammler Elisabetta Munzone Lorenzo Gianni Beat Th ürlimann Istv án Láng Marco Colleoni Sherene Loi Giuseppe Viale Meredith M Regan Laurence Buisseret Fran çoise Rothé Christos Sot Source Type: research
Emerging proteins involved in castration ‑resistant prostate cancer via the AR‑dependent and AR‑independent pathways (Review)
Int J Oncol. 2023 Nov;63(5):127. doi: 10.3892/ijo.2023.5575. Epub 2023 Sep 21.ABSTRACTDespite achieving optimal initial responses to androgen deprivation therapy, most patients with prostate cancer eventually progress to a poor prognosis state known as castration‑resistant prostate cancer (CRPC). Currently, there is a notable absence of reliable early warning biomarkers and effective treatment strategies for these patients. Although androgen receptor (AR)‑independent pathways have been discovered and acknowledged in recent years, the AR signaling pathway continues to play a pivotal role in the progression of CRPC. The ...
Source: International Journal of Oncology - September 21, 2023 Category: Cancer & Oncology Authors: Kangle Feng Chunhua Liu Weixi Wang Piaoping Kong Zhihua Tao Weiwei Liu Source Type: research
