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Condition: Pain
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Total 151079 results found since Jan 2013.
Efficacy of a gluten-free diet in reducing the widespread pain index and symptom severity scale in patients affected by fibromyalgia
CONCLUSIONS: A GFD improved FM symptoms evaluated with WPI and SS. This was confirmed for the first time, also with a rechallenge of the GFD that followed a non-restricted gluten-containing diet.PMID:37721353 | DOI:10.4081/reumatismo.2023.1530
Source: Reumatismo - September 18, 2023 Category: Rheumatology Authors: V Bruzzese C Marrese P Scolieri J Pepe Source Type: research
Oxidative stress may be a contributing factor in fibromyalgia patients' pain mechanisms
CONCLUSIONS: Reactive oxygen species have several negative impacts on the human body. As a result of the measurements we analyzed, the relationship between FM and oxidative stress should be studied in terms of disease progression and may help improve the treatment process.PMID:37721351 | DOI:10.4081/reumatismo.2023.1550
Source: Reumatismo - September 18, 2023 Category: Rheumatology Authors: H Beyaztas S Aktas E M Guler E Ata Source Type: research
Vasculitis associated with adenosine deaminase 2 deficiency: at the crossroads between Beh çet's disease and autoinflammation. A viewpoint
Reumatismo. 2023 Sep 18;75(3). doi: 10.4081/reumatismo.2023.1578.ABSTRACTAdenosine deaminase 2 deficiency (DADA2) is a rare monogenic vasculopathy caused by loss-of-function homozygous or compound heterozygous mutations in ADA2, formerly CECR1 (cat eye syndrome chromosome region 1) gene. The DADA2 phenotype is widely heterogeneous, and patients may present with fever, weight loss, livedo reticularis/racemosa, digital ischemia, cutaneous ulceration, peripheral neuropathy, abdominal pain, bowel perforation, and portal or nephrogenic hypertension. More specific manifestations include early-onset ischemic or hemorrhagic stroke...
Source: Reumatismo - September 18, 2023 Category: Rheumatology Authors: A Colangelo F Tromby G Cafaro R Gerli E Bartoloni C Perricone Source Type: research
Psychological variables associated with resistance to treatment with serotonin and noradrenaline reuptake inhibitors in fibromyalgia
CONCLUSIONS: FM T[+] and FM T[-] differ in clinical presentation and psychological features. The levels of affective temperaments, personality and schizotypal traits are associated with lack response to SNRI in FM.PMID:37722212 | DOI:10.1016/j.jpsychores.2023.111493
Source: Pain Physician - September 18, 2023 Category: Anesthesiology Authors: Anna J Krupa Adrian A Chrobak Zbigniew So łtys Mariusz Korkosz Jaros ław Nowakowski Dominika Dudek Marcin Siwek Source Type: research
Hip joint imaging findings in football players with hip and groin pain (PhD Academy Award)
Br J Sports Med. 2023 Sep 18:bjsports-2023-107317. doi: 10.1136/bjsports-2023-107317. Online ahead of print.NO ABSTRACTPMID:37722768 | DOI:10.1136/bjsports-2023-107317
Source: British Journal of Sports Medicine - September 18, 2023 Category: Sports Medicine Authors: Joshua J Heerey Source Type: research
Postpartum health of working mothers: A prospective study
CONCLUSION: The prevalence of postnatal depression was higher during the first 6 weeks of postpartum than after 12 weeks of postpartum. Screening and treatment of poor postpartum mental health among working women are essential owing to the impacts on occupational outcomes.PMID:37719695 | PMC:PMC10504895 | DOI:10.51866/oa.167
Source: Pain Physician - September 18, 2023 Category: Anesthesiology Authors: Anak Janting Majorie Ensayan Whye Lian Cheah Hazmi Helmy Source Type: research
A Very Unusual Presentation of Miliary Tuberculosis and Osteomyelitis as an Incidental Finding of Musculoskeletal Pain
Cureus. 2023 Aug 27;15(8):e44207. doi: 10.7759/cureus.44207. eCollection 2023 Aug.ABSTRACTTuberculosis (TB) is a highly infectious disease that takes the primary or latent route. In primary TB, the patient often presents with constitutional symptoms such as cough, fever, weight loss, and hemoptysis. This 83-year-old patient was sent to the emergency department (ED) by her primary care physician after abnormal imaging for acute back and neck pain. Imaging revealed pulmonary TB with possible tuberculosis osteomyelitis versus metastatic carcinoma to the cervical vertebrae. The case's unique presentation gives light to the nee...
Source: Pain Physician - September 18, 2023 Category: Anesthesiology Authors: Prachi B Patel Bhavi Purohit Source Type: research
Clinical Application of Inferior Alveolar Nerve Block Device for Safe and Secure IANB by Any Operator
Pain Res Manag. 2023 Sep 8;2023:1021918. doi: 10.1155/2023/1021918. eCollection 2023.ABSTRACTThe inferior alveolar nerve block (IANB) is an established technique with a success rate of 60-80%; however, large errors have been reported among operators. Some dentists do not prefer to use IANB because of the risk of complications. Nevertheless, it is a useful technique for pain control, and a secure IANB offers significant benefits to operators and patients. This case series study aimed to investigate the efficacy of the "IANB Device," a nerve block guide for IANB, and the adverse events associated with its use in clinical pra...
Source: Pain Research and Management - September 18, 2023 Category: Anesthesiology Authors: Tomoyasu Noguchi Kento Odaka Ken-Ichi Fukuda Source Type: research
The Relationship between Pain Catastrophizing and Cognitive Function in Chronic Musculoskeletal Pain: A Scoping Review
CONCLUSION: Although evidence exists for the relationship between cognitive function and PC, there is a lack of rigorous research to indicate the strength of this relationship and the specific cognitive functions affected. The literature lacks appropriate populations needed to investigate clinically relevant PC and is limited by heterogeneous neuropsychological test batteries. Future research should include populations demonstrating the behaviors being studied, intentional analysis of outcomes, and appropriate cognitive tests.PMID:37719894 | PMC:PMC10505081 | DOI:10.1155/2023/5851450
Source: Pain Research and Management - September 18, 2023 Category: Anesthesiology Authors: Cory Alcon Elizabeth Bergman John Humphrey Rupal M Patel Sharon Wang-Price Source Type: research
Long-term outcomes of prophylaxis with a recombinant factor VIII Fc or recombinant factor IX Fc in patients with hemophilia previously treated on demand
CONCLUSIONS: Findings add to existing evidence and demonstrate the clinical and HRQoL benefits of switching patients from on-demand treatment to rFVIIIFc/rFIXFc prophylaxis.PMID:37720484 | PMC:PMC10502440 | DOI:10.1016/j.rpth.2023.102163
Source: Thrombosis and Haemostasis - September 18, 2023 Category: Hematology Authors: Mar ía-Teresa Álvarez-Román Amy D Shapiro Margaret V Ragni Helena Palmborg Linda Bystrick á Johan Szamosi Sandra Casiano Herv é Chambost Source Type: research
High-Sensitivity Cardiac Troponin Assays: Ready for Prime Time!
Annu Rev Med. 2023 Sep 18. doi: 10.1146/annurev-med-051022-113931. Online ahead of print.ABSTRACTRapid and accurate triage of patients presenting with chest pain to an emergency department (ED) is critical to prevent ED overcrowding and unnecessary resource use in individuals at low risk of acute myocardial infarction (AMI) and to efficiently and effectively guide patients at high risk to definite therapy. The use of biomarkers for rule-out or rule-in of suspected AMI has evolved substantially over the last several decades. Previously well-established biomarkers have been replaced by cardiac troponin (cTn). High-sensitivit...
Source: Annual Review of Medicine - September 18, 2023 Category: General Medicine Authors: Konstantin A Krychtiuk L Kristin Newby Source Type: research
Clinical and Epidemiological Profile of Herpes Zoster and Its Complications in a Tertiary Care Center of Bihar: A Prospective Study
Conclusion A broader understanding of the clinical and epidemiological factors of herpes zoster and post-herpetic complications is important as this disease constitutes a considerable burden in a tertiary care center and if not treated adequately, the after-effects might last for many years altogether. Hence, early diagnosis and initiation of adequate antiviral therapy as well as pain management is the key aspect of management.PMID:37719532 | PMC:PMC10503883 | DOI:10.7759/cureus.43560
Source: Herpes - September 18, 2023 Category: Infectious Diseases Authors: Rajesh Sinha Pinki Kumari U K Pallavi Subhasree Sarkar Source Type: research
Do educational interventions improve prescribing skills of medical students compared to no additional learning? A systematic review
Med Educ Online. 2023 Dec;28(1):2259166. doi: 10.1080/10872981.2023.2259166. Epub 2023 Sep 18.ABSTRACTResearch suggests that medical students are not confident and may be ill-prepared to prescribe competently. Therefore, changes to standard education may be required to fortify medical student prescribing skills, confidence, and competence. However, specific education to write a safe and legal prescription is generally lacking. Furthermore, the term prescribe and the skill thereof is not clearly defined. This review compares additional education for medical students to no identified additional education or another education...
Source: Medical Education Online - September 18, 2023 Category: Universities & Medical Training Authors: Sophie M Mokrzecki Andrew Mallett Tarun Sen Gupta Stephen Perks Tilley Pain Source Type: research
Regulation of nociception threshold by norepinephrine through adrenergic α2 receptor in rat models of Parkinson's disease
CONCLUSIONS: The change of norepinephrine content can affect the activation of prefrontal and cingulate gyrus glial cells and participate in the regulation of nociception threshold in PD rats. Adrenergic α2 receptor agonist and central presynaptic membrane α2 receptor blocker both affect cell activation and improve hyperalgesia.PMID:37721421 | DOI:10.1111/cns.14446
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Qing Gao Yingying Zhang Xiaoying Wang Rui Wang Limei Zhang Source Type: research
Effectiveness and Safety of Eliglustat Treatment in Gaucher Disease: Real-Life Unicentric Experience
In this study, we evaluated the effectiveness and safety of eliglustat in a cohort of 12 patients with GD followed up in our center, reporting a reduction in both chitotriosidase (394.3 vs 181.1 nmol/h/mL, P = 0.027) and glucosylsphingosine values (45.1 vs 18.9 ng/mL, P <0.001) after at least 12 months of therapy compared with baseline, regardless of patient demographic characteristics and GD characteristics.FINDINGS: There were no drug-related serious adverse effects and no drug-related cardiac events. Most adverse events were mild and transient, mainly dyspepsia and abdominal pain. Of interest, we reported an absence ...
Source: Clinical Therapeutics - September 18, 2023 Category: Drugs & Pharmacology Authors: Andrea Duminuco Manlio Fazio Stephanie Grasso Lara Gullo Carla Riccobene Valeria Calafiore Uros Markovic Francesco Di Raimondo Gaetano Giuffrida Source Type: research
