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Infectious Disease: Pandemics
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Total 138118 results found since Jan 2013.
How does the Immunological System Change during the SARS-COV-2 Attack? A Clue for the New Immunotherapy Discovery
Curr Med Chem. 2023 Sep 18. doi: 10.2174/0929867331666230918092749. Online ahead of print.ABSTRACTThe COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2) is one of the biggest unsolved global problems of the 21st century for which there has been no definitive cure yet. Like other respiratory viruses, SARS-COV-2 triggers the host immunity dramatically, causing dysfunction in the immune system, both innate and adaptive, which is a common feature of COVID-19 patients. Evidence shows that in the early stages of COVID-19, the immune system is suppressed while it is overactive in severe p...
Source: Current Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Mohammad Mahdi Hajihasani Najmeh Kaffash Farkhad Ali Mahmoudi Amirhossein Sahebkar Source Type: research
Addressing Opportunities and Barriers in Telehealth Neurologic Physical Therapy: Strategies to Advance Practice
This article highlights the potential and future of telehealth in neurologic PT practice. Our recommendations provide current clinical tools and resources for telehealth implementation following a knowledge-to-action framework and suggest areas for future research.Video Abstract available for more insights from the authors (see the Video, the Supplemental Digital Content, available at: http://links.lww.com/JNPT/A447).PMID:37725807 | DOI:10.1097/NPT.0000000000000454
Source: Physical Therapy - September 19, 2023 Category: Physiotherapy Authors: Aimee E Perron Hina Garg Sarah Gallagher Brittany Kennedy Sara Oxborough Emily Schultz Gregory Thielman Qing Zhang Source Type: research
Emergency Department waiting-time in the post pandemic era: new organizational models, a challenge for the future
CONCLUSIONS: data show an increase in the time spent in the EDs and an increase in the overcrowding, according to the NEDOCS index. New management models and a reorganization of EDs are needed as the workload has increased significantly.PMID:37724561 | DOI:10.23750/abm.v94iS3.14262
Source: Acta Bio-Medica : Atenei Parmensis - September 19, 2023 Category: General Medicine Authors: Giuseppe Stirparo Erika Kacerik Aida Andreassi Paolo Pausilli Francesca Cortellaro Anna Coppo Maurizio Migliari Andrea Albonico Giuseppe Maria Sechi Alberto Zoli Carlo Signorelli Source Type: research
Family physicians' questions about the COVID-19 pandemic: a content analysis of 2,272 helpline calls
CONCLUSIONS: This research provides unique insight on the effects the COVID-19 pandemic had on family medicine in Canada. These results provide insights on the needs and information gaps of family physicians in a public health crisis and can inform preparedness efforts by public health agencies, professional organizations, educators, and practitioners.PMID:37726697 | DOI:10.1186/s12875-023-02147-w
Source: Primary Care - September 19, 2023 Category: Primary Care Authors: Allan McDougall Jacqueline H Fortier Cathy Zhang Caroline Ehrat Kerri Best Heather Blois Gary Garber Source Type: research
The influence of explainable vs non-explainable clinical decision support systems on rapid triage decisions: a mixed methods study
CONCLUSIONS: Although overall trust in the models was low, the median (IQR) weight-on-advice was high (0.33 (0.0-0.56)) and in line with published literature on expert advice. In contrast to the hypothesis, weight-on-advice was comparable between the explaining and non-explaining systems. In 30% of cases, weight-on-advice was 0, meaning the physician did not change their rating. The median of the remaining weight-on-advice values was 50%, suggesting that physicians either dismissed the recommendation or employed a "meeting halfway" approach. Newer technologies, such as clinical reasoning systems, may be able to augment the...
Source: Pain Physician - September 19, 2023 Category: Anesthesiology Authors: Daniel Laxar Magdalena Eitenberger Mathias Maleczek Alexandra Kaider Fabian Peter Hammerle Oliver Kimberger Source Type: research
A Review of Studies on the Covid-19 Pandemic and the Psychological Effects of Related Measures on Children, Youth and Parents
Turk Psikiyatri Derg. 2023 Fall;34(3):202-214. doi: 10.5080/u25936.ABSTRACTPandemics are social events that affect individuals' lives in many ways and have a significant impact on the mental health of masses. Pandemics and measures taken to combat these epidemics affect children and young people as well as adults. The purpose of the current review is to compile studies that have been conducted on the psychological effects of the COVID-19 pandemic and related measures on children, youth, and parents, and use the findings to shed light on future studies. In this review, 35 studies that were determined as a result of a compre...
Source: Turkish Journal of Psychiatry - September 19, 2023 Category: Psychiatry Authors: Burcu Altin G ülsen Erden Source Type: research
Evaluation of the Impact of the COVID-19 Pandemic on Cystic Echinococcosis Indirect Hemagglutination Test Dynamics: A Single-center Experience
CONCLUSION: A significant decrease was observed in the rate of IHA positivity during the pandemic period. The status of no increase in positivity rates despite a significant decrease in IHA tests makes us think that the diagnosis may be missed in some patients or that there could be disruptions in their follow-up. For this reason, in order to continue the fight successfully against CE, which is an important public health problem for our country, early diagnosis and regular follow-ups should be emphasized with educations, and the laboratory-clinician communication should be strengthened in order to use tests more efficientl...
Source: Turkish Society for Parasitology - September 19, 2023 Category: Parasitology Authors: Özlem Ulusan Bağcı Source Type: research
Preclinical evaluation of a SARS-CoV-2 variant B.1.351-based candidate DNA vaccine
Vaccine. 2023 Sep 17:S0264-410X(23)01091-5. doi: 10.1016/j.vaccine.2023.09.021. Online ahead of print.ABSTRACTThe SARS-CoV-2 pandemic revealed the critical shortfalls of global vaccine availability for emergent pathogens and the need for exploring additional vaccine platforms with rapid update potential in response to new variants. Thus, it remains essential, for the present evolving SARS-CoV-2/Covid-19 and future pandemics, to continuously develop and characterize new and different vaccine platforms. Here, we describe an expression-optimized DNA vaccine candidate based on the SARS-CoV-2 spike protein of the Beta variant (...
Source: Vaccine - September 19, 2023 Category: Allergy & Immunology Authors: Ria Lassauni ère Charlotta Polacek Jeanette Linnea Tingstedt Anders Fomsgaard Source Type: research
Patient-reported reactogenicity and safety of COVID-19 vaccinations vs. comparator vaccinations: a comparative observational cohort study
CONCLUSION: The rate of adverse reactions after established vaccinations was roughly comparable to previous studies. Two weeks after vaccination, participants in the SARS-CoV-2 vaccination group reported more local and systemic local reactions than participants in the comparator group. In the further course, however, there were no higher odds of medical consultations in either of the two groups. Thus, altogether, we assume comparable safety.TRIAL REGISTRATION: DRKS-ID DRKS00025881 and DRKS-ID DRKS00025373.PMID:37726711 | DOI:10.1186/s12916-023-03064-6
Source: Herpes - September 19, 2023 Category: Infectious Diseases Authors: Felix Werner Nikoletta Zeschick Thomas K ühlein Philipp Steininger Klaus Überla Isabelle Kaiser Maria Sebasti ão Susann Hueber Lisette Warkentin Source Type: research
Evolution of the surgical procedure gap during and after the COVID-19 pandemic in Ontario, Canada: cross-sectional and modelling study
Br J Surg. 2023 Sep 19:znad289. doi: 10.1093/bjs/znad289. Online ahead of print.NO ABSTRACTPMID:37724806 | DOI:10.1093/bjs/znad289
Source: The British Journal of Surgery - September 19, 2023 Category: Surgery Authors: Rachel Stephenson Vahid Sarhangian Jangwon Park Ashwin Sankar Nancy N Baxter Therese A Stukel Andrea N Simpson Duminda N Wijeysundera Andrew S Wilton Charles de Mestral Stephen W Hwang Daniel Pincus Robert J Campbell David R Urbach Jonathan Irish David Go Source Type: research
Physician and administrator experience of preparing to implement Ontario's intensive care unit Triage Emergency Standard of Care during the COVID-19 pandemic: a qualitative study
CMAJ Open. 2023 Sep 19;11(5):E838-E846. doi: 10.9778/cmajo.20220168. Print 2023 Sep-Oct.ABSTRACTBACKGROUND: As the COVID-19 pandemic created a surge in demand for critical care resources, the province of Ontario, Canada, released the Adult Critical Care Clinical Emergency Standard of Care for Major Surge (Emergency Standard of Care [ESoC]), a triage framework to guide the allocation of critical care resources in the expectation that intensive care units would be overwhelmed. Our aim was to understand physicians' and administrators' experiences and perceptions of planning to implement the ESoC, and to identify ways to impro...
Source: cmaj - September 19, 2023 Category: General Medicine Authors: Brandon A Heidinger Ariane Downar Andrea Frolic James Downar Sarina R Isenberg Source Type: research
Addressing Opportunities and Barriers in Telehealth Neurologic Physical Therapy: Strategies to Advance Practice
This article highlights the potential and future of telehealth in neurologic PT practice. Our recommendations provide current clinical tools and resources for telehealth implementation following a knowledge-to-action framework and suggest areas for future research.Video Abstract available for more insights from the authors (see the Video, the Supplemental Digital Content, available at: http://links.lww.com/JNPT/A447).PMID:37725807 | DOI:10.1097/NPT.0000000000000454
Source: Health Physics - September 19, 2023 Category: Physics Authors: Aimee E Perron Hina Garg Sarah Gallagher Brittany Kennedy Sara Oxborough Emily Schultz Gregory Thielman Qing Zhang Source Type: research
A Review of Studies on the Covid-19 Pandemic and the Psychological Effects of Related Measures on Children, Youth and Parents
Turk Psikiyatri Derg. 2023 Fall;34(3):202-214. doi: 10.5080/u25936.ABSTRACTPandemics are social events that affect individuals' lives in many ways and have a significant impact on the mental health of masses. Pandemics and measures taken to combat these epidemics affect children and young people as well as adults. The purpose of the current review is to compile studies that have been conducted on the psychological effects of the COVID-19 pandemic and related measures on children, youth, and parents, and use the findings to shed light on future studies. In this review, 35 studies that were determined as a result of a compre...
Source: Turk Psikiyatri Dergisi - September 19, 2023 Category: Psychiatry Authors: Burcu Altin G ülsen Erden Source Type: research
Maternal Mental Health, COVID-19-Related Distress, and Disruptions in Lifestyle Behaviors Among Postpartum Mothers With a Previous Hypertensive Disorder of Pregnancy
CONCLUSION: Monitoring PTSD symptoms may be vital in supporting mothers with hypertensive disorders of pregnancy in making lifestyle changes to prevent cardiovascular disease.PMID:37723619 | DOI:10.1097/JCN.0000000000001038
Source: The Journal of Cardiovascular Nursing - September 19, 2023 Category: Nursing Authors: Jewel Scott Alisse Hauspurg Esa M Davis Samantha Bryan Janet M Catov Source Type: research
A large survey on COVID-19 vaccination in patients with Parkinson's disease and healthy population
CONCLUSIONS: The COVID-19 vaccination rate was remarkably lower in PD patients than healthy individuals in China. The approved vaccines have shown an acceptable safety profile. Our findings would offer a reference to guide future clinical decision-making of COVID-19 vaccination and improve the immunization management of PD patients.PMID:37726180 | DOI:10.1016/j.vaccine.2023.09.002
Source: Vaccine - September 19, 2023 Category: Allergy & Immunology Authors: Chao Han Zhen Zhen Zhao Piu Chan Fang Li Chun Ling Chi Xin Zhang Yan Zhao Jing Chen Jing Hong Ma Source Type: research
