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Infectious Disease: Influenza

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Total 16629 results found since Jan 2013.

Development of dynamic model identification criteria for infectious disease symptom association: The case of influenza in Chinese population
Asian J Surg. 2023 Sep 9:S1015-9584(23)01391-X. doi: 10.1016/j.asjsur.2023.08.233. Online ahead of print.NO ABSTRACTPMID:37696698 | DOI:10.1016/j.asjsur.2023.08.233
Source: Asian Journal of Surgery - September 11, 2023 Category: Surgery Authors: Tianlu Yin Xiaohuan Gao Dayan Wang Hongpu Hu Source Type: research

Antiviral Compounds to Address Influenza Pandemics: An Update from 2016-2022
Curr Med Chem. 2023 Sep 7. doi: 10.2174/0929867331666230907093501. Online ahead of print.ABSTRACTIn recent decades, the world has gained experience of the dangerous effects of pandemic events caused by emerging respiratory viruses. In particular, annual epidemics of influenza are responsible for severe illness and deaths. Even if conventional influenza vaccines represent the most effective tool for preventing virus infections, they are not completely effective in patients with severe chronic disease and immunocompromised and new small molecules have emerged to prevent and control the influenza viruses. Thus, the attention ...
Source: Current Medicinal Chemistry - September 11, 2023 Category: Chemistry Authors: Roberto Romeo Laura Legnani Maria Assunta Chiacchio Salvatore V Giofr è Daniela Iannazzo Source Type: research

Vaccine Effectiveness of non-adjuvanted and adjuvanted trivalent inactivated influenza vaccines in the prevention of influenza-related hospitalization in older adults: A pooled analysis from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN)
CONCLUSIONS: Adjusting for frailty, aTIV showed statistically significantly better protection than naTIV against influenza-associated hospitalizations in older adults. In future studies, it is important to consider frailty as a significant confounder of VE.PMID:37696717 | DOI:10.1016/j.vaccine.2023.08.070
Source: Vaccine - September 11, 2023 Category: Allergy & Immunology Authors: Henrique Pott Melissa K Andrew Zachary Shaffelburg Michaela K Nichols Lingyun Ye May ElSherif Todd F Hatchette Jason LeBlanc Ardith Ambrose Guy Boivin William Bowie Jennie Johnstone Kevin Katz Phillipe Lagac é-Wiens Mark Loeb Anne McCarthy Allison McGeer Source Type: research

Development of dynamic model identification criteria for infectious disease symptom association: The case of influenza in Chinese population
Asian J Surg. 2023 Sep 9:S1015-9584(23)01391-X. doi: 10.1016/j.asjsur.2023.08.233. Online ahead of print.NO ABSTRACTPMID:37696698 | DOI:10.1016/j.asjsur.2023.08.233
Source: Asian Journal of Surgery - September 11, 2023 Category: Surgery Authors: Tianlu Yin Xiaohuan Gao Dayan Wang Hongpu Hu Source Type: research

Antiviral Compounds to Address Influenza Pandemics: An Update from 2016-2022
Curr Med Chem. 2023 Sep 7. doi: 10.2174/0929867331666230907093501. Online ahead of print.ABSTRACTIn recent decades, the world has gained experience of the dangerous effects of pandemic events caused by emerging respiratory viruses. In particular, annual epidemics of influenza are responsible for severe illness and deaths. Even if conventional influenza vaccines represent the most effective tool for preventing virus infections, they are not completely effective in patients with severe chronic disease and immunocompromised and new small molecules have emerged to prevent and control the influenza viruses. Thus, the attention ...
Source: Current Medicinal Chemistry - September 11, 2023 Category: Chemistry Authors: Roberto Romeo Laura Legnani Maria Assunta Chiacchio Salvatore V Giofr è Daniela Iannazzo Source Type: research

Healthcare personnel in 2016-2019 prospective cohort infrequently got vaccinated, worked while ill, and frequently used antibiotics rather than antivirals against viral influenza illnesses
Influenza Other Respir Viruses. 2023 Sep 7;17(9):e13189. doi: 10.1111/irv.13189. eCollection 2023 Sep.ABSTRACTBACKGROUND: Uncertainty about risk of illness and the value of influenza vaccines negatively affects vaccine uptake among persons targeted for influenza vaccination.METHODS: During 2016-2019, we followed a cohort of healthcare personnel (HCP) targeted for free-of-charge influenza vaccination in five Lima hospitals to quantify risk of influenza, workplace presenteeism (coming to work despite illness), and absenteeism (taking time off from work because of illness). The HCP who developed acute respiratory illnesses (A...
Source: Respiratory Care - September 11, 2023 Category: Respiratory Medicine Authors: Eduardo Azziz-Baumgartner Joan Neyra Tat S Yau Giselle Soto Daniel Owusu Chao Zhang Candice Romero Young M Yoo Miriam Gonzales Yeny Tinoco Mar ía Silva Eduar Bravo Nancy Rojas Serrano Eduardo Matos Victor Chavez-Perez Juan Carlos Castro Maria Esther Cast Source Type: research

Vaccine Effectiveness of non-adjuvanted and adjuvanted trivalent inactivated influenza vaccines in the prevention of influenza-related hospitalization in older adults: A pooled analysis from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN)
CONCLUSIONS: Adjusting for frailty, aTIV showed statistically significantly better protection than naTIV against influenza-associated hospitalizations in older adults. In future studies, it is important to consider frailty as a significant confounder of VE.PMID:37696717 | DOI:10.1016/j.vaccine.2023.08.070
Source: Vaccine - September 11, 2023 Category: Allergy & Immunology Authors: Henrique Pott Melissa K Andrew Zachary Shaffelburg Michaela K Nichols Lingyun Ye May ElSherif Todd F Hatchette Jason LeBlanc Ardith Ambrose Guy Boivin William Bowie Jennie Johnstone Kevin Katz Phillipe Lagac é-Wiens Mark Loeb Anne McCarthy Allison McGeer Source Type: research

A recombinant chimeric influenza virus vaccine expressing the consensus H3 hemagglutinin elicits broad hemagglutination inhibition antibodies against divergent swine H3N2 influenza viruses
This study focuses on the hemagglutinin (HA) consensus-based approach towards developing a more broadly protective swine influenza vaccine against various H3 strains circulating in domestic pig populations. By computationally analyzing >1000 swine H3 full-length HA sequences, we generated a consensus H3 and expressed it in the context of influenza A WSN/33 reverse genetics system. The derived recombinant chimeric swine influenza virus with the consensus H3 was inactivated and further evaluated as a potential universal vaccine in pigs. The consensus H3 vaccine elicited broadly active hemagglutination inhibition (HI) anti...
Source: Vaccine - September 9, 2023 Category: Allergy & Immunology Authors: Jieshi Yu Chithra Sreenivasan Zhizhang Sheng Shao-Lun Zhai Jared W Wollman Sisi Luo Chen Huang Rongyuan Gao Zhao Wang Radhey S Kaushik Jane Christopher-Hennings Eric Nelson Ben M Hause Feng Li Dan Wang Source Type: research

Reverse transcription recombinase-aided amplification assay combined with a lateral flow dipstick for detection of duck Tembusu virus
J Virol Methods. 2023 Sep 7:114810. doi: 10.1016/j.jviromet.2023.114810. Online ahead of print.ABSTRACTDuck Tembusu virus disease, caused by duck Tembusu virus (DTMUV), brings great harm to duck industry. Early diagnosis is of great significance for the prevention and control of this disease. In order to develop a specific and sensitive method for rapid diagnosis of DTMUV, reverse-transcriptase recombinase aided amplification combined with lateral flow dipstick (RT-RAA-LFD) method for detection of DTMUV was established. Firstly, downstream primer was labeled with biotin and probe was labeled with FAM, and primer concentrat...
Source: Journal of Virological Methods - September 9, 2023 Category: Virology Authors: Yixin Wang Xue Zhang Zhenyan Zhang Ruixue Xu Pingping Yang Peng Yuan Lianzhi Zhang Yanshun Cui Zhijing Xie Jianliang Li Source Type: research

A recombinant chimeric influenza virus vaccine expressing the consensus H3 hemagglutinin elicits broad hemagglutination inhibition antibodies against divergent swine H3N2 influenza viruses
This study focuses on the hemagglutinin (HA) consensus-based approach towards developing a more broadly protective swine influenza vaccine against various H3 strains circulating in domestic pig populations. By computationally analyzing >1000 swine H3 full-length HA sequences, we generated a consensus H3 and expressed it in the context of influenza A WSN/33 reverse genetics system. The derived recombinant chimeric swine influenza virus with the consensus H3 was inactivated and further evaluated as a potential universal vaccine in pigs. The consensus H3 vaccine elicited broadly active hemagglutination inhibition (HI) anti...
Source: Vaccine - September 9, 2023 Category: Allergy & Immunology Authors: Jieshi Yu Chithra Sreenivasan Zhizhang Sheng Shao-Lun Zhai Jared W Wollman Sisi Luo Chen Huang Rongyuan Gao Zhao Wang Radhey S Kaushik Jane Christopher-Hennings Eric Nelson Ben M Hause Feng Li Dan Wang Source Type: research

TWiV 1042: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses China’s health authorities fighting surge in cases of Mpox unknown origin, analysis of seasonal variation of antibiotic prescribing for respiratory tract diagnoses in primary care practices, prevalence and associated outcomes of co-infection between SARS-CoV-2 and influenza, comparison of bivalent and monovalent mRNA vaccine boosters, optimal duration of systemic corticosteroids in COVID-19 treatment, acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization, temporal changes in fecal microbiota of patients infected with C...
Source: This Week in Virology - MP3 Edition - September 9, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

A discussion about influenza from the perspective of "latent dryness"
J Tradit Chin Med. 2023 Oct;43(5):839-840. doi: 10.19852/j.cnki.jtcm.2023.05.001.NO ABSTRACTPMID:37679970 | PMC:PMC10465827 | DOI:10.19852/j.cnki.jtcm.2023.05.001
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Wang Yongyan W U Shengxian Source Type: research

HVT-vectored H7 vaccine protects chickens from lethal infection with the highly pathogenic H7N9 Avian in fluenza virus
Vet Microbiol. 2023 Aug 20;285:109852. doi: 10.1016/j.vetmic.2023.109852. Online ahead of print.ABSTRACTSince mid-2016, the highly pathogenic H7N9 subtype avian influenza virus (AIV) has threatened both public health and the poultry industry. Although a vaccination strategy has been deemed imperative to manage the virus, the most commonly used inactivated vaccines today are susceptible to interference from maternal antibodies and associated with an over-reliance on humoral immunity. In response, we developed a recombination vaccine with the herpesvirus of turkeys (HVT) as the vector to squeeze HPAI H7N9 and assessed its pr...
Source: Herpes - September 8, 2023 Category: Infectious Diseases Authors: Yi-Qun Chen Guan-Ming Su Jia-Hao Zhang Bo Li Kai-Xiong Ma Xu Zhang Li-Hong Huang Ming Liao Wen-Bao Qi Source Type: research

Global burden of influenza lower respiratory tract infections in older people from 1990 to 2019
CONCLUSION: Efforts to improve vaccination for influenza are needed for preparedness of another influenza pandemic, especially in low-SDI regions.PMID:37682492 | DOI:10.1007/s40520-023-02553-1
Source: Aging Clinical and Experimental Research - September 8, 2023 Category: Geriatrics Authors: Jing-Nan Feng Hou-Yu Zhao Si-Yan Zhan Source Type: research