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Perpetuation of household food insecurity during COVID-19 in South Africa
CONCLUSIONS: South Africa needs to address socioeconomic challenges and inequalities to assist the perpetually food insecure and to ensure that, should there be a pandemic resurgence, or a new pandemic, individuals and households in the country are in a better financial situation and appropriately supported to avoid food insecurity at all costs.PMID:37700382 | PMC:PMC10498595 | DOI:10.1186/s41043-023-00441-y
Source: Journal of Health, Population, and Nutrition - September 12, 2023 Category: International Medicine & Public Health Authors: Nicole De Wet-Billings Source Type: research

Burdening Perspectives and Treatment Modalities of Monkeypox: A Central Dogma
Infect Disord Drug Targets. 2023 Aug 25. doi: 10.2174/1871526523666230825164222. Online ahead of print.ABSTRACTThe monkeypox virus (MPXV), belonging to the genus Orthopoxvirus, is responsible for causing the zoonotic illness known as Monkeypox. The virus was initially identified during an outbreak at a Danish Zoo in 1958 and has since been found to infect various mammal species worldwide. While African squirrels and other rodents are believed to be the primary hosts, determining the natural host has proven challenging. While MPXV can be studied using different animal models in laboratory settings, understanding its natural...
Source: Infectious Disorders Drug Targets - September 12, 2023 Category: Infectious Diseases Authors: Shivang Dhoundiyal Md Aftab Alam Awaneet Kaur Sandesh Varshney Source Type: research

An overview of protein-based SARS-CoV-2 vaccines
Vaccine. 2023 Sep 10:S0264-410X(23)01067-8. doi: 10.1016/j.vaccine.2023.09.013. Online ahead of print.ABSTRACTSARS-CoV-2 resulted in the COVID-19 pandemic which, to date, has resulted in an estimated loss of over 15 million human lives globally and continues to have negative social, and economic implications worldwide. Vaccine platforms that can be quickly updated to counter newly emerging SARS-CoV-2 variants are critical in combating the COVID-19 pandemic. Messenger RNA-based SARS-CoV-2 vaccines can be easily updated and have shown superior efficacy over other vaccine types, yet their high cost, reactogenicity, and string...
Source: Vaccine - September 12, 2023 Category: Allergy & Immunology Authors: Yogesh R Suryawanshi Source Type: research

Meeting report: Towards better risk stratification, prevention and therapy of invasive GBS disease, ESPID research meeting May 2022
Vaccine. 2023 Sep 10:S0264-410X(23)01068-X. doi: 10.1016/j.vaccine.2023.09.014. Online ahead of print.ABSTRACTThe European Society of Pediatric Infectious Diseases (ESPID) hosted the third Group B Streptococcus (GBS) Research Session in Athens on 11th May 2022, providing researchers and clinicians from around the world an opportunity to share and discuss recent advances in GBS pathophysiology, molecular and genetic epidemiology and how these new insights can help in improving prevention and control of early- and late-onset GBS disease. The meeting provided a state-of-the-art overview of the existing GBS prevention strategi...
Source: Vaccine - September 12, 2023 Category: Allergy & Immunology Authors: Linde Snoek Konstantinos Karampatsas Merijn W Bijlsma Philipp Henneke Elita Jauneikaite Uzma B Khan Ruth N Zadoks Kirsty Le Doare Source Type: research

Genomic associations with antibody response to an oral cholera vaccine
Vaccine. 2023 Sep 10:S0264-410X(23)01084-8. doi: 10.1016/j.vaccine.2023.09.016. Online ahead of print.ABSTRACTOral cholera vaccine is one of the key interventions used in our fight to end the longest pandemic of our time, cholera. The immune response conferred by the currently available cholera vaccines, as measured by serum antibody levels, is variable amongst its recipients. We undertook a genome wide association study (GWAS) on antibody response to the cholera vaccine; globally, the first GWAS on cholera vaccine response. We identified three clusters of bi-allelic SNPs, in high within-cluster linkage disequilibrium that...
Source: Vaccine - September 12, 2023 Category: Allergy & Immunology Authors: Vijay Laxmi Roy Partha P Majumder Source Type: research

Comparative effectiveness of mRNA-1273 and BNT162b2 COVID-19 vaccines in immunocompromised individuals: a systematic review and meta-analysis using the GRADE framework
ConclusionThis GRADE meta-analysis based on a large number of consistent observational studies showed that the mRNA-1273 COVID-19 vaccine is associated with improved clinical effectiveness in IC populations compared with BNT162b2.
Source: Frontiers in Immunology - September 12, 2023 Category: Allergy & Immunology Source Type: research

Threads blocks searches related to covid and vaccines amid surge
LOS ANGELES — Instagram’s text-based social platform Threads last week rolled out its new search function, a crucial step toward the platform’s expansion and one that would give it more parity with X, the formerly known as Twitter. Tech is not your friend. We are. Sign up for The Tech Friend…#threads #twitter #techfriend #luckytran #columbiauniversity #cdc #juliadoubleday #worldhealthnetwork #meta #facebookandinstagram
Source: Reuters: Health - September 11, 2023 Category: Consumer Health News Source Type: news

Rolling e-learning: an educational model to support Italian healthcare professionals during the COVID-19 pandemic
CONCLUSIONS: Italian healthcare professionals working during the pandemic overwhelmingly appreciated and valued the rolling e-learning offer aimed at widening the dissemination of the best practices on COVID-19. This educational model provides independent, evidence-based and tailored information with the undoubted advantages of time flexibility, remote participation and continuous update, all elements that make it a useful tool in a pandemic as well as in a post-pandemic era.PMID:37695199 | DOI:10.23750/abm.v94iS3.14204
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Fabrizio Ernesto Pregliasco Maria Rosa Valetto Filippo Anelli Ugo Moretti Nicoletta Scarpa Pietro Dri Source Type: research

Compliance with recommended preventive behaviours and restrictions for Covid-19: an exploratory analysis of Italians' attitudes
CONCLUSIONS: government's fear-based interventions did not seem to work since Italians tended to adhere to the rules primarily out of respect for legitimate authority. Future research should focus more on the topic of trust in institutions in emergency situations with the aim of highlighting the key points for successful governance, also in terms of rules compliance.PMID:37695183 | DOI:10.23750/abm.v94iS3.14431
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Guido Travaini Emma Flutti Lorenzo Blandi Roberta Sala Sarah Songhorian Palmina Caruso Giulia Mugellini Source Type: research

Can youtube be trusted as a source of quality and reliable information on COVID-19 vaccination in Italy?
CONCLUSIONS: These findings suggest that public health professionals and institutions should consider investing in social media representation to fill the gap with non-medical sources in terms of popularity, to provide reliable and interesting videos, and ultimately deliver health education to the general public.PMID:37695176 | DOI:10.23750/abm.v94iS3.14558
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Leandro Gentile Paola Bertuccio Angela Ancona Andrea Cucchi Giulia Dallagiacoma Martino Alberto Godoy Carlo Signorelli Anna Odone Source Type: research

Promoting societal resilience during the COVID-19 pandemic: a multi-country analysis of public health strategies
CONCLUSIONS: The COVID-19 pandemic highlighted the importance of Public Health in developing proper strategies and utilizing digitals tools to counteract infodemic and spread relevant information. Healthcare workers should improve their communication skills to face future epidemics and be trusted by the population. Social media and digital platforms should be studied and used effectively in times of emergency.PMID:37695174 | DOI:10.23750/abm.v94iS3.14562
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Anna Carole D'Amelio Sarah Cataldi Giulia Dallagiacoma Leandro Gentile Anna Odone Carlo Signorelli Source Type: research

Herpes zoster in a patient with first onset of childhood nephrotic syndrome following the second SARS-CoV-2 vaccination
CEN Case Rep. 2023 Sep 11. doi: 10.1007/s13730-023-00818-2. Online ahead of print.NO ABSTRACTPMID:37695475 | DOI:10.1007/s13730-023-00818-2
Source: Herpes - September 11, 2023 Category: Infectious Diseases Authors: Kaoru Nakashima Tomoko Horinouchi Yu Tanaka Yuta Ichikawa Kandai Nozu Source Type: research

Antibody effector functions are required for broad and potent protection of neonates from herpes simplex virus infection
bioRxiv. 2023 Aug 31:2023.08.29.555423. doi: 10.1101/2023.08.29.555423. Preprint.ABSTRACTThe failure of multiple herpes simplex virus (HSV) vaccine candidates that induce neutralizing antibody responses raises the hypothesis that other activities, such as Fc domain-dependent effector functions, may be critical for protection. While neonatal HSV (nHSV) infection result in mortality and lifelong neurological morbidity in humans, it is uncommon among neonates with a seropositive birthing parent, suggesting the potential efficacy of antibody-based therapeutics to protect neonates. We therefore investigated the mechanisms of mo...
Source: Herpes - September 11, 2023 Category: Infectious Diseases Authors: Matthew D Slein Iara M Backes Callaghan R Garland Natasha S Kelkar David A Leib Margaret E Ackerman Source Type: research

Growing Deficit in New Cancer Diagnoses 2 Years Into the COVID-19 Pandemic: A National Multicenter Study
CONCLUSION: Disruptions in new diagnoses of four common cancers (prostate, lung, bladder, and colorectal) seen early in the COVID-19 pandemic have persisted for 2 years. Although reductions improved from the early pandemic, new reductions during the Delta and Omicron waves demonstrate the continued impact of the COVID-19 pandemic on cancer care.PMID:37695458 | DOI:10.1245/s10434-023-14217-5
Source: Ann Oncol - September 11, 2023 Category: Cancer & Oncology Authors: Brian R Englum Shalini Sahoo Minerva Mayorga-Carlin Hilary Hayssen Tariq Siddiqui Douglas J Turner John D Sorkin Brajesh K Lal Source Type: research