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Vaccination: Vaccines
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Total 88601 results found since Jan 2013.
Neonatal erythema multiforme associated with a rotavirus infection: A case report
CONCLUSION: The possibility of rotavirus, a major cause of pediatric gastrointestinal infections, being a trigger for neonatal EM should be considered.PMID:37727716 | PMC:PMC10506005 | DOI:10.12998/wjcc.v11.i24.5749
Source: Herpes - September 20, 2023 Category: Infectious Diseases Authors: Jung Jae Kim Joon Kee Lee Source Type: research
Human CD34 < sup > + < /sup > -derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8 < sup > + < /sup > T cell and NK cell responses in vitro and in vivo
In this study, we aimed to dissect the phenotypic identity of these non-DCs and their potential immune modulatory functions on the potency of cDCs and pDCs in stimulating tumor-reactive CD8+ T and NK cell responses, in order to obtain rationale for clinical translation of our DC-complete vaccine. The non-DC compartment was heterogeneous and comprised of myeloid progenitors and (immature) granulocyte- and monocyte-like cells. Importantly, non-DCs potentiated toll-like receptor-induced DC maturation, as reflected by increased expression of co-stimulatory molecules and enhanced cDC-derived IL-12 and pDC-derived IFN-α product...
Source: Cellular and Molecular Life Sciences : CMLS - September 20, 2023 Category: Cytology Authors: Jesper van Eck van der Sluijs Diede van Ens Jolanda Brummelman Daan Heister Aastha Sareen Lisa Truijen Dorette S van Ingen Schenau Mirjam H M Heemskerk Marieke Griffioen Michel G D Kester Nicolaas P M Schaap Joop H Jansen Anniek B van der Waart Harry Dols Source Type: research
Vaccination coverage in children under one year of age and associated socioeconomic factors: maps of spatial heterogeneity
CONCLUSIONS: the results are useful for designing interventions regarding the structuring of vaccination services and the implementation of actions to increase vaccination coverage in clusters with less propensity to vaccinate.PMID:37729269 | DOI:10.1590/0034-7167-2022-0734
Source: Revista Brasileira de Enfermagem - September 20, 2023 Category: Nursing Authors: Matheus Adriano Divino Pereira Luis Henrique Arroyo Maria Del Pilar Serrano Gallardo Ricardo Alexandre Arc êncio Josianne Dias Gusm ão Gabriela Gon çalves Amaral Val éria Conceição de Oliveira Eliete Albano de Azevedo Guimar ães Source Type: research
Barriers to the success of COVID-19 immunisation programs in New Ireland Province, Papua New Guinea
CONCLUSION: Vaccine hesitancy is a significant problem that has the potential to negatively affect population-level health. An urgent focused effort to strengthen immunisation programs in PNG is evident. Preventative primary health care is a national priority; however, for the successful delivery of vaccination initiatives, well-formed immunisation programs that include education that will dispel myths and misinformation are required.PMID:37730242 | DOI:10.22605/RRH7883
Source: Rural Remote Health - September 20, 2023 Category: Rural Health Authors: Belinda Flanagan Kay Nevill Camilla Sabok Mimi Zilliacus Jonathon Sward Source Type: research
Evaluation the effect of dietary vitamin E, sesamin and thymoquinone bioactive compounds on immunological response, intestinal traits and MUC-2 gene expression in broiler Japanese quails ( < em > Coturnix japonica < /em > )
Anim Biotechnol. 2023 Sep 20:1-11. doi: 10.1080/10495398.2023.2259437. Online ahead of print.ABSTRACTThe current study was performed to determine the effect of dietary vitamin E, sesamin and thymoquinone bioactive lignans derived from sesame and black seed on immunological response, intestinal traits and Mucin2 gene expression in broiler quails. Three hundred and fifty (one days-old) quails were allotted to seven dietary treatments with five replicates as an experimental randomized design study. Treatments were basal diet as a control, control +100 and +200 mg of vitamin E, sesamin and thymoquinone per each kg of diet resp...
Source: Animal Biotechnology - September 20, 2023 Category: Biotechnology Authors: Yaser Rahimian Farshid Kheiri Mostafa Faghani Source Type: research
Comment on COVID-19 vaccine hesitancy and health literacy
Am J Manag Care. 2023 Sep 1;29(9):e261. doi: 10.37765/ajmc.2023.89427.ABSTRACTThis letter discusses COVID-19 vaccine hesitancy and health literacy.PMID:37729530 | DOI:10.37765/ajmc.2023.89427
Source: The American Journal of Managed Care - September 20, 2023 Category: Health Management Authors: Amnuay Kleebayoon Viroj Wiwanitkit Source Type: research
Personalized neoantigen cancer vaccines: An analysis of the clinical and commercial potential of ongoing development programs
Drug Discov Today. 2023 Sep 18:103773. doi: 10.1016/j.drudis.2023.103773. Online ahead of print.ABSTRACTNeoantigen cancer vaccines harbor promise as next-generation immuno-oncology therapies, whereby cancer vaccines are tailored to the patient's tumor antigen and represent the future of personalized cancer therapy. While several biotech companies have ongoing development programs, little has been published about the true commercial potential of these innovative therapies and the challenges these products will face upon regulatory approval. In this paper, we provide an overview of neoantigen cancer vaccine development progr...
Source: Drug Discovery Today - September 20, 2023 Category: Drugs & Pharmacology Authors: Maurice Perrinjaquet C Richard Schlegel Source Type: research
Paediatric COVID-19 vaccination coverage and associated factors among migrant and non-migrant children aged 5-11 years in Aotearoa New Zealand: A population-level retrospective cohort study
CONCLUSIONS: The findings suggest that NZ's paediatric COVID-19 vaccination programme was able to address logistical and motivational barriers commonly identified amongst migrants and refugees.IMPLICATIONS FOR PUBLIC HEALTH: As parents' vaccination status is an important factor in vaccinating their own children, continuous efforts are needed to support confident parental COVID-19 vaccine decision-making. To address social inequities, engagement with marginalised communities to co-design tailored and localised approaches is recommended.PMID:37729755 | DOI:10.1016/j.anzjph.2023.100086
Source: Australian and New Zealand Journal of Public Health - September 20, 2023 Category: International Medicine & Public Health Authors: Nadia A Charania Linda Kirkpatrick Janine Paynter Source Type: research
What evidence for a cholera vaccine? Jaime Ferr án's submissions to the Prix Bréant
This article analyses how the French Academy of Sciences assessed Jaime Ferrán's cholera vaccine submitted for the Prix Bréant in the 1880s. Ferrán, a Spanish independent physician, discovered the treatment in 1884 and tried it on thousands of patients during the cholera outbreak in Valencia the following year. His evaluation sparked a controversy in Spain and abroad on the vaccine's efficacy. The Bréant jury did not see any evidence for it in Ferrán's submission, a decision usually interpreted in terms of French scientific nationalism (or simple chauvinism): an outsider from the scientific periphery could not be awar...
Source: Medical History - September 19, 2023 Category: History of Medicine Authors: Clara Uzcanga David Teira Source Type: research
A measles virus-based vaccine induces robust chikungunya virus-specific CD4 < sup > + < /sup > T-cell responses in a phase II clinical trial
Vaccine. 2023 Sep 17:S0264-410X(23)01092-7. doi: 10.1016/j.vaccine.2023.09.022. Online ahead of print.ABSTRACTChikungunya virus (CHIKV) is an alphavirus transmitted by mosquitos that causes a debilitating disease characterized by fever and long-lasting polyarthralgia. To date, no vaccine has been licensed, but multiple vaccine candidates are under evaluation in clinical trials. One of these vaccines is based on a measles virus vector encoding for the CHIKV structural genes C, E3, E2, 6K, and E1 (MV-CHIK), which proved safe in phase I and II clinical trials and elicited CHIKV-specific antibody responses in adult measles ser...
Source: Vaccine - September 19, 2023 Category: Allergy & Immunology Authors: Katharina S Schmitz Anouskha D Comvalius Nella J Nieuwkoop Daryl Geers Daniela Weiskopf Katrin Ramsauer Alessandro Sette Roland Tschismarov Rory D de Vries Rik L de Swart Source Type: research
A large survey on COVID-19 vaccination in patients with Parkinson's disease and healthy population
CONCLUSIONS: The COVID-19 vaccination rate was remarkably lower in PD patients than healthy individuals in China. The approved vaccines have shown an acceptable safety profile. Our findings would offer a reference to guide future clinical decision-making of COVID-19 vaccination and improve the immunization management of PD patients.PMID:37726180 | DOI:10.1016/j.vaccine.2023.09.002
Source: Vaccine - September 19, 2023 Category: Allergy & Immunology Authors: Chao Han Zhen Zhen Zhao Piu Chan Fang Li Chun Ling Chi Xin Zhang Yan Zhao Jing Chen Jing Hong Ma Source Type: research
Preclinical evaluation of a SARS-CoV-2 variant B.1.351-based candidate DNA vaccine
Vaccine. 2023 Sep 17:S0264-410X(23)01091-5. doi: 10.1016/j.vaccine.2023.09.021. Online ahead of print.ABSTRACTThe SARS-CoV-2 pandemic revealed the critical shortfalls of global vaccine availability for emergent pathogens and the need for exploring additional vaccine platforms with rapid update potential in response to new variants. Thus, it remains essential, for the present evolving SARS-CoV-2/Covid-19 and future pandemics, to continuously develop and characterize new and different vaccine platforms. Here, we describe an expression-optimized DNA vaccine candidate based on the SARS-CoV-2 spike protein of the Beta variant (...
Source: Vaccine - September 19, 2023 Category: Allergy & Immunology Authors: Ria Lassauni ère Charlotta Polacek Jeanette Linnea Tingstedt Anders Fomsgaard Source Type: research
Patient-reported reactogenicity and safety of COVID-19 vaccinations vs. comparator vaccinations: a comparative observational cohort study
CONCLUSION: The rate of adverse reactions after established vaccinations was roughly comparable to previous studies. Two weeks after vaccination, participants in the SARS-CoV-2 vaccination group reported more local and systemic local reactions than participants in the comparator group. In the further course, however, there were no higher odds of medical consultations in either of the two groups. Thus, altogether, we assume comparable safety.TRIAL REGISTRATION: DRKS-ID DRKS00025881 and DRKS-ID DRKS00025373.PMID:37726711 | DOI:10.1186/s12916-023-03064-6
Source: Herpes - September 19, 2023 Category: Infectious Diseases Authors: Felix Werner Nikoletta Zeschick Thomas K ühlein Philipp Steininger Klaus Überla Isabelle Kaiser Maria Sebasti ão Susann Hueber Lisette Warkentin Source Type: research
Student Perceptions of a New Course Using Argumentation in Medical Education
CONCLUSION: These findings support evidence from educational scholarship outside of medicine showing argumentation as a learning tool is well received by students. Further work is needed to determine whether it improves critical thinking skills and enhances learning in medical education.PMID:37724185 | PMC:PMC10505381 | DOI:10.2147/AMEP.S394219
Source: Adv Data - September 19, 2023 Category: Epidemiology Authors: Andrew J Foy Kent E Vrana Paul Haidet Bernice L Hausman Nancy E Adams Ira Ropson Daniel R Wolpaw David Rabago Richard B Mailman Xuemei Huang Source Type: research
Development in the Inhibition of Dengue Proteases as Drug Targets
CONCLUSION: Different classes of compounds have been reported against DENV, such as nitrogen-containing heterocycles (i.e., imidazole, pyridine, triazoles quinazolines, quinoline, and indole), oxygen-containing heterocycles (i.e., coumarins), and some are mixed heterocyclic compounds of S, N (thiazole, benzothiazine, and thiazolidinediones), and N, O (i.e., oxadiazole). There have been reports of computationally designed compounds to impede the molecular functions of specific structural and non-structural proteins as potential therapeutic targets. This review summarized the current progress in developing dengue protease in...
Source: Current Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Muhammad Akram Shehryar Hameed Abbas Hassan Khalid Khan Source Type: research
