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Nimg-01. a case report of neurosarcoidosis presenting as a lymphoma mimic
DISCUSSION:Our patient did not have Lymphoma, and had a good response to corticosteroids and infliximab. However, his clinical presentation raised suspicion for lymphoma. Biopsy in these types of cases is necessary to establish correct diagnosis. Neurosarcoidosis has no known cure. Immunosuppression is the principal method of treatment, and corticosteroids are the cornerstone of therapy.
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Kaur, G., Cameron, L. Tags: NEURO-IMAGING Source Type: research

Practical Approach to the Tele-Neuro-Ophthalmology and Neuro-Otology Visits: Instructional Videos
Abstract: A collection of instructional videos that illustrate a step by step approach to tele-neuro-ophthalmology and neuro-otology visits. These videos provide instruction for patient preparation for their video visit, patient and provider interface with an electronic medical record associated video platform, digital applications to assist with vision testing, and practical advice for detailed remote neuro-ophthalmologic and neuro-otologic examinations.
Source: Journal of Neuro-Ophthalmology - February 25, 2021 Category: Opthalmology Tags: Technology in Neuro-Ophthalmology Source Type: research

Nc-13 * cranial radiation encompassing the genu is associated with neuro-psychological sequelae in children: a prospective study of diffusion tensor imaging (dti) and proton mr spectroscopy (mrs)
CONCLUSIONS: The genu is a region with increased susceptibility to injury associated with neuro-psychological sequelae. Efforts should be made to limit radiation dose to this region during treatment planning.
Source: Neuro-Oncology - November 3, 2014 Category: Cancer & Oncology Authors: Redmond, K., Mahone, M., Sair, H., Vannorsdall, T., Terezakis, S., Kleinberg, L., McNutt, T., Wharam, M., Horska, A. Tags: NEURO-COGNITIVE AND FUNCTIONAL OUTCOMES Source Type: research

Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery.
Abstract There is a growing body of evidence that carmustine wafer implantation during surgery is an effective therapeutic adjunct to the standard combined radio-chemotherapy regimen using temozolomide in newly diagnosed and recurrent high-grade glioma patient management with a statistically significant survival benefit demonstrated across several randomized clinical trials, as well as prospective and retrospective studies (grade A recommendation). Compelling clinical data also support the safety of carmustine wafer implantation (grade A recommendation) in these patients and suggest that observed adverse events ca...
Source: Neuro-Chirurgie - November 6, 2017 Category: Neurosurgery Authors: Roux A, Caire F, Guyotat J, Menei P, Metellus P, Pallud J, Neuro-Oncology Club of the French Neurosurgical Society Tags: Neurochirurgie Source Type: research

Teaching Neuro-Ophthalmology in the Asia-Pacific Region and China: A Personal Perspective
Abstract: Over the last 30 years, I have been involved in a number of projects helping to educate and train local ophthalmologists in many parts of Asia and the Pacific Islands, which lack adequate training and service in neuro-ophthalmology. In this article, I offer an overview of a number of different teaching initiatives and offer practical suggestions to anyone who might wish to become involved.
Source: Journal of Neuro-Ophthalmology - November 22, 2015 Category: Opthalmology Tags: Worldwide Neuro-Ophthalmology Source Type: research

Neuro-Ophthalmic Injuries With Systemic Neurologic Injury or Traumatic Brain Injury in Operation Iraqi Freedom and Operation Enduring Freedom
Background: To analyze the final visual acuity (VA) of neuro-ophthalmologic injuries (NOI) in combat ocular trauma and to study the association of NOI with systemic neurologic injury (SNI) and traumatic brain injury (TBI). Methods: The Walter Reed Ocular Trauma Database was reviewed. Inclusion criteria were any US service member and Department of Defense civilians who suffered NOI, SNI, or TBI in Operation Iraqi Freedom or Operation Enduring Freedom. The primary outcome measure was the rate of poor final VA in patients with an NOI with secondary outcome measures the rate of SNI and TBI. in patients with NOI. Results:...
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Clinical Research: Epidemiology Meets Neuro-Ophthalmology Source Type: research

Conjunctival Biopsy to Diagnose Neurosarcoidosis in Patients with Inflammatory Nervous System Disease of Unknown Etiology (P1.339)
CONCLUSIONS: This study demonstrates that conjunctival biopsy has low diagnostic yield to discover neurosarcoidosis in patients with presumed inflammatory nervous system disease and suggests that alternative diagnostic means should be pursued.Disclosure: Dr. Pichler has nothing to disclose. Dr. Flanagan has nothing to disclose. Dr. Aksamit has nothing to disclose. Dr. Leavitt has nothing to disclose. Dr. Salomao has nothing to disclose. Caridian BCT
Source: Neurology - April 8, 2015 Category: Neurology Authors: Pichler, M., Flanagan, E., Aksamit, A., Leavitt, J., Salomao, D., Keegan, M. Tags: Neuro-ophthalmology/Neuro-otology I Source Type: research

Neuro-Ophthalmic Manifestations of Sarcoidosis
Conclusions: Patients with neurosarcoidosis may present initially with a neuro-ophthalmic manifestation, and this presentation may be more common in older patients. MRI usually is abnormal, although findings may be nonspecific. Serum testing for ACE is not helpful. Normal CT chest does not rule out underlying sarcoidosis, particularly in white patients.
Source: Journal of Neuro-Ophthalmology - November 22, 2021 Category: Opthalmology Tags: Original Contribution Source Type: research

Ophthalmic and neuro-ophthalmic manifestations of sarcoidosis
Purpose of review Sarcoidosis is a multisystemic inflammatory disease that commonly affects the eye and less often the neuro-ophthalmic pathways. The manifestations can be quite variable but can have characteristic signs and clinical features. This review provides a comprehensive overview of the various ocular and neuro-ophthalmic manifestations of sarcoidosis, emerging diagnostic measures and approach to treatment. Particular focus is given to recent advances in diagnostic approach and available treatment options. Recent findings Laboratory investigations, chest and nuclear medicine imaging remain important techniques fo...
Source: Current Opinion in Ophthalmology - October 12, 2017 Category: Opthalmology Tags: NEURO-OPHTHALMOLOGY: Edited by Dean M. Cestari Source Type: research

Neurosarcoidosis: Pathophysiology, Diagnosis, and Treatment
Although often regarded as a protean illness with myriad clinical and imaging manifestations, neurosarcoidosis typically presents as recognizable syndromes that can be approached in a rational, systematic fashion. Understanding of neurosarcoidosis has progressed significantly in recent years, including updated diagnostic criteria and advances in treatment. The diagnosis of neurosarcoidosis is established by the clinical syndrome, imaging and histopathological findings, and exclusion of other causes. Mounting evidence supports the use of tumor necrosis factor inhibitors as an important addition to the therapeutic armamentar...
Source: Neurology Neuroimmunology and Neuroinflammation - October 4, 2021 Category: Neurology Authors: Bradshaw, M. J., Pawate, S., Koth, L. L., Cho, T. A., Gelfand, J. M. Tags: Optic neuritis; see Neuro-ophthalmology/Optic Nerve, Transverse myelitis Views [amp ] Reviews Source Type: research

Neurosarcoidosis and Ocular Inflammation: A Case Series and Literature Review
Conclusion: NS is an uncommon, but potentially life-threatening, manifestation of sarcoidosis with ocular involvement up to 25% of patients. Patients presenting with neuro-ophthalmic manifestations of sarcoidosis are more likely to have other sites of involvement requiring ophthalmologists to maintain a high index of suspicion for systemic disease.
Source: Journal of Neuro-Ophthalmology - June 1, 2021 Category: Opthalmology Tags: Trainees' Corner Source Type: research

Neurosarcoidosis Masquerading as Giant Cell Arteritis With Incidental Meningioma
We present a case of vision loss secondary to neurosarcoidosis, which initially presented with severe bilateral vision loss, temporal headaches, and elevated erythrocyte sedimentation rate, concerning for giant cell arteritis. However, temporal artery biopsy was negative. Initial neuroimaging features were misinterpreted to represent a meningioma that did not account for his clinical presentation. Clinical course, including atypically rapid enlargement of presumed meningioma, development of skin lesions, appearance of optic nerve enhancement on MRI, and steroid response, strongly increased suspicion for sarcoidosis. Biopsy...
Source: Journal of Neuro-Ophthalmology - February 25, 2021 Category: Opthalmology Tags: Photo Essay Source Type: research

Neuro-Ophthalmic Manifestations of Intracranial Malignancies
Conclusion: Intracranial malignancies can present with neuro-ophthalmic symptoms or signs depending on topographical localization. Specific neuro-ophthalmic presentations are associated with different malignant intracranial tumors. Clinicians should be aware of the common malignant intracranial tumors and their associated clinical presentations in neuro-ophthalmology.
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Trainees' Corner Source Type: research

Diagnostic Error of Neuro-ophthalmologic Conditions: State of the Science
Conclusions: As an emerging field, diagnostic error in neuro-ophthalmology offers rich opportunities for further research and improvement of quality of care.
Source: Journal of Neuro-Ophthalmology - February 25, 2021 Category: Opthalmology Tags: State-of-the-Art Review Source Type: research

Afferent and Efferent Neuro-Ophthalmic Complications of Coronavirus Disease 19
Conclusions: The literature on COVID-associated neuro-ophthalmic disease continues to grow. Afferent neuro-ophthalmic complications associated with COVID-19 include optic neuritis, papillophlebitis, papilledema, visual disturbance associated with posterior reversible encephalopathy syndrome, and vision loss caused by stroke. Efferent neuro-ophthalmic complications associated with COVID-19 include cranial neuropathies, Miller Fisher syndrome, Adie's pupils, ocular myasthenia gravis, nystagmus and eye movement disorders. Proposed mechanisms of neurologic disease include immunologic upregulation, vasodilation and vascular...
Source: Journal of Neuro-Ophthalmology - June 1, 2021 Category: Opthalmology Tags: Disease of the Year: COVID-19 Source Type: research