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A new drug for influenza
A new drug has been approved by the US Food and Drug Administration for the treatment of influenza. Called Xofluza (baloxavir carboxyl), it is the first influenza drug approved in 20 years with a new mechanism of action. How does Xofluza work? Influenza virus particles contain (-) RNAs, which means that they cannot be translated […]
Source: virology blog - October 25, 2018 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information antiviral Baloxavir carboxyl cap dependent endonuclease influenza oseltamivir virus viruses Xofluza Source Type: blogs

An easy method for preventing the flu
Thanks to Lori, this morning I read a very interesting article in Forbes magazine about how to (help) prevent getting the flu AND how to lower hospital infections. Such a simple, easy thing we can all do… Have a look: http://bit.ly/31RP6QT Very very interesting…makes sense, too!
Source: Margaret's Corner - October 28, 2019 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll preventing the flu Source Type: blogs

Stomach flu
A couple of weeks ago I came down with a nasty case of viral gastroenteritis, more commonly known as the stomach flu. No idea how I got it…but…I got it. Well, at least Covid wasn’t involved in my case; my family doctor told me that a (small) percentage of his patients with my symptoms had turned up positive for Covid. That would have been a most unwelcome double whammy! Petunia, October 2022 Anyway, I was quite sick for about a week, sleeping most of the time, eating nothing but bananas and toast, and watching heaps of TV series and documentaries…The cats were very helpful nurses, always by my side,...
Source: Margaret's Corner - October 31, 2022 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll stomach flu Source Type: blogs

Human infections with influenza H5N1 virus: How many?
The lethality of avian influenza H5N1 infections in humans has been a matter of extensive debate. The >50% case fatality rate established by WHO is high, but the lethality of the virus might be lower if there are many infections accompanied by mild or no disease. One way to answer this question is to determine how many individuals carry antibodies to the virus in populations that are at risk for infection. A number of such studies have been done, and some have concluded that the results imply a low but substantial level of infection (even less than one percent of millions of people is a lot of infections). The conclusio...
Source: virology blog - February 7, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Commentary Information antibodies avian influenza H5N1 bioterrorism case fatality ratio fatality rate infection pandemic serological survey serosurvey viral virus Source Type: blogs

How a toupee compromised influenza vaccine
The influenza virus vaccine is frequently updated to ensure that it protects against infection with circulating virus strains. In some years the vaccine matches the circulating strains, but in others, there is a mismatch. The result is that the vaccine is less effective at protecting from infection. During the 2014-15 influenza season there was a […]
Source: virology blog - November 30, 2017 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information antibody antigenic drift embryonated chicken egg glycan glycosylation HA influenza virus vaccine vaccine escape viral Source Type: blogs

TWiV 495: Influenza virus keeps its ion channel 20
The TWiVerati follow up on the Ebola virus outbreak, virulence of Ebola-Makona, and reveal how a parasitoid is revealed to hyperparasitoids, and binding of influenza virus to a calcium ion channel to mediate influenza virus entry. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: […]
Source: virology blog - May 27, 2018 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology A82V caterpillar ebola virus endocytosis hyperparasitoid influenza virus ion channel parasitoid wasp polydnavirus viral virulence viruses voltage gated calcium channel Source Type: blogs

How Scientists Use Statistical Deception to Fake Influenza Vaccine Effectiveness
Statistical manipulation misinforms people by use of false measurements. Vaccine scientists often conceal the true effectiveness of the influenza vaccine through risk calculations. Researchers use a calculation that essentially artificially inflates the effectiveness of influenza vaccines. Rather than use the statistical measure that more truthfully represents vaccine effectiveness, the researchers choose to use a statistical […] VacTruth.com
Source: vactruth.com - August 10, 2018 Category: Allergy & Immunology Authors: Tom Stavola Tags: Influence & Psychology Absolute Risk Reduction (ARR) influenza vaccine Relative Risk (RR) Risk Calculation Statistical Deception Source Type: blogs

WHO report on human cases of avian influenza A(H7N9) infection
The World Health Organization has been publishing weekly reports on the avian influenza A(H7N9) outbreak which include the geographical location of each case, the cumulative number of cases, and the epidemiological curve. Go to this page at the WHO website for an archive of the weekly reports (there you will also find other useful information on the H7N9 outbreak). Images for report #3 of 24 April 2013 are reproduced below. Click each image for a larger view.
Source: virology blog - April 25, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information avian influenza H7N9 China pandemic Shanghai viral virus WHO world health organization Source Type: blogs

Update on influenza H7N9 virus at ASM in Denver
At the 2013 ASM meeting in Denver, Colorado, Stanley Maloy discussed human infections with avian influenza H7N9 virus with Ronald Atlas, Ph.D., University of Louisville, KY; Robert Webster; St. Jude’s Research Hospital, Memphis, TN; Albert Osterhaus; Erasmus Medical Center, Rotterdam, The Netherlands; and Carole Heilman, NIAID, NIH, Bethesda, MD.
Source: virology blog - May 22, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information Albert Osterhaus avian influenza H7N9 Carole Heilman China H2N9 H5N1 pandemic Robert Webster Ron Atlas Stan Maloy viral virus Source Type: blogs

Influenza H7N9 gain of function experiments on Dispatch Radio
I spoke with Robert Herriman, executive editor of The Global Dispatch, about the proposed avian influenza H7N9 virus gain of function experiments on Dispatch Radio.
Source: virology blog - August 14, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Commentary Information fouchier gain of function h7n9 influenza kawaoka viral virus Source Type: blogs

The alphanumeric soup known as influenza
Robert Herriman, co-founder of The Global Dispatch, recently started a radio show called Outbreak News This Week. Robert calls the show “Your source for all the news about worms and germs”. He covers the latest news and information about infectious diseases and often includes interviews with expert guests. The show can be heard live Saturday mornings at 7:30 am EST on on The Tan Talk Radio Network: 1340 AM WTAN Clearwater, 1350 AM WDCF Dade City and 1400 AM WZHR Zephyrhills. You can also listen online. I have been a frequent guest on Robert’s Outbreak News This Week, most recently this past Saturday, when we had...
Source: virology blog - January 21, 2014 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information India influenza outbreak news polio poliovirus Robert Herriman vaccine viral Source Type: blogs

Avian influenza and Ebola update
Avian influenza has been found at a second and third location in the Netherlands:The second is in Ter Aar - GuardianThe third is in Kamperveen, confirmed as H5N8 - De Volkskrant (in Dutch) De Volkskrant is also reporting a new case of Ebola in Mali, and has a graphic showing the present situation.  The captions are of course in Dutch, and English language alternatives for current statistics are CDC and WHO.  The CDC site has a graphic on the right.
Source: Browsing - November 22, 2014 Category: Databases & Libraries Tags: avian influenza Ebola Source Type: blogs

Avian influenza (Vogelgriep)
Just discovered this official Dutch government site, in (of course) Dutch, which has a complete record of the affected sites in the Netherlands,  (go to Overzicht or Inhoud, then Locaties vogelgriep), as well as news and links to official publications.  As well as sites where the virus has been found, it also lists places that have been investigated but nothing found, so not every place listed has had the virus.I can find nothing new about avian influenza in the UK.  The UK government site about the discovery of the virus in Yorkshire was updated today (3rd December) but that seems to be relating to rules ab...
Source: Browsing - December 3, 2014 Category: Databases & Libraries Tags: avian influenza Source Type: blogs