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Influenza vaccines for individuals with egg allergy
A CDC (US) advisory committee has recommended the use of FluBlok for individuals with egg allergy:
The Advisory Committee on Immunization Practices (ACIP) voted today, 13 to 0, in favor of recommending FluBlok during the 2013-2014 influenza season for vaccination of persons 18 through 49 years of age with egg allergy of any severity.
FluBlok is an influenza virus vaccine that is produced by expressing the influenza virus hemagglutinin (HA) protein in insect cells using a baculovirus vector. Baculoviruses are rod-shaped viruses (see photograph) that infect insects and other arthropods. The baculovirus virion contains a dou...
Source: virology blog - June 27, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information baculovirus FluBlok Flucelvax HA influenza insect cell vaccine viral Source Type: blogs
Seriously, Just Get The Flu Shot
Did you get your flu shot yet?
Our family was a bit delayed in getting our shots this year and sure enough – yep, one of the girls got it!
Watching my very healthy 12-year-old struggle with a high fever and crazy coughing was tough. I can’t imagine the toll it would take on someone who isn’t as healthy.
The rest of us rushed out and got our flu shots. So far, (do you hear me knocking on wood?) none of the rest of us have fallen ill.
I know – no one likes a shot. Yet, a little poke in the arm is a small price to pay to avoid a potentially fatal infection.
Many people are confused about the flu an...
Source: Embrace Your Heart Wellness Initiative - January 17, 2013 Category: Cardiology Authors: Eliz Greene Tags: Award Winning Blog Heart Health busy woman's guide to a healthy heart Flu shot and heart health Healthy Families women's wellness Source Type: blogs
Further defense of the Chinese H1N1 – H5N1 study
Robert Herriman of The Global Dispatch interviewed me this week on the H1N1 – H5N1 reassortant study that has been in the headlines:
There was much written concerning the research published earlier this month in Science, where researchers from China’s Harbin Veterinary Research Institute reported creating an avian H5N1 (highly pathogenic) and pandemic 2009 H1N1 (easily transmissible) hybrid, that according to them, achieved airborne spread between guinea pigs.
Read the rest of the article at The Global Dispatch.
Source: virology blog - May 17, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information aerosol transmission avian influenza H5N1 ferret guinea pig H1N1 reassortant viral virus Source Type: blogs
Just like for H1N1, the Ebola conspiracy theory machine goes into overdrive
Does anyone remember the H1N1 influenza pandemic? As hard as it is to believe, that was five years ago. One thing I remember about the whole thing is just how crazy both the antivaccine movement and conspiracy theorists (but I repeat myself) went over the public health campaigns to vaccinate people against H1N1. It was…
Source: Respectful Insolence - October 16, 2014 Category: Surgery Authors: Orac Tags: Antivaccine nonsense Medicine Pseudoscience Quackery Skepticism/critical thinking AIDS Andrew Wakefield Barbara Loe Fisher Brian Hooker CDC CDC whistleblower conspiracy theory Denialism Ebola Ebola virus feargasm H1N1 HIV Source Type: blogs
Just as the H1N1 conspiracy theory machine did in 2009, the Ebola conspiracy theory machine goes into overdrive
Does anyone remember the H1N1 influenza pandemic? As hard as it is to believe, that was five years ago. One thing I remember about the whole thing is just how crazy both the antivaccine movement and conspiracy theorists (but I repeat myself) went over the public health campaigns to vaccinate people against H1N1. It was…
Source: Respectful Insolence - October 16, 2014 Category: Surgery Authors: Orac Tags: Antivaccine nonsense Medicine Pseudoscience Quackery Skepticism/critical thinking AIDS Andrew Wakefield Barbara Loe Fisher Brian Hooker CDC CDC whistleblower conspiracy theory Denialism Ebola Ebola virus feargasm H1N1 HIV Source Type: blogs
No, the CDC did not just apologize and admit that this year’s flu vaccine doesn’t work, part 2
It looks like this year’s going to be a bad flu season. Hard as it is for me to believe, it was only five weeks ago when I discussed an announcement by the CDC that this year’s flu vaccine would likely be less effective because it isn’t a good match for the influenza strains in…
Source: Respectful Insolence - January 16, 2015 Category: Surgery Authors: Orac Tags: Antivaccine nonsense Autism Biology Complementary and alternative medicine Quackery Science CDC influenza Source Type: blogs
Encouraging clinical data for universal flu vaccine candidate
by Helen Stillwell The results from a phase I clinical trial to test the safety and immunogenicity of a universal flu vaccine candidate reported encouraging results – strong titers of broad and functional antibodies persisted for over a year in healthy adults following vaccination. Influenza viruses contain segmented RNA genomes. The viral envelope contains two types glycoproteins […]
Source: virology blog - December 17, 2020 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Helen Stilwell antibody HA stem influenza phase I clinical trial universal flu vaccine viral virus viruses Source Type: blogs
Flu Virus-Inspired Nanoparticles for mRNA Delivery
Researchers at the University of California San Diego developed a new delivery technique for mRNA. The method involves flu virus-inspired nanoparticles that can escape endosomes, the acidic vesicles that engulf and destroy materials that attempt to e...
Source: Medgadget - December 13, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Medicine Nanomedicine Public Health flu mRNA vaccine UCSD Source Type: blogs
Telemedicine, Accenture, and Influenza App – Around Healthcare Scene
Discussion About EMR Study by Accenture
Source: EMR and HIPAA - January 28, 2013 Category: Technology Consultants Authors: Katie Tags: EHR EHR Benefits Electronic Health Record Electronic Medical Record EMR EMR Consulting EMR Implementation Healthcare HealthCare IT Hospital EHR Hospitals mHealth Accenture Around Healthcare Scene CDC CDC Influenza App Source Type: blogs
Influenza A(H7N9) Cases in China Increase to 38
The World Health Organization (WHO) announced ten new cases of influenza A(H7N9) virus in China today. This brings the total number of cases to 38. WHO says 10 of the 38 infected people have died.
WHO says in a FAQ that the exact source of A(H7N9) is unknown. The virus was found in a pigeon in a Shanghai market. There is still no evidence of ongoing human-to-human transmission. 760 close contacts with the confirmed cases are being monitored.
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Source: HealthNewsBlog.com - April 12, 2013 Category: Health Medicine and Bioethics Commentators Tags: flu bird-flu influenza Source Type: blogs
CDC Says Influenza Vaccinations Prevented 79,000 Flu Hospitalizations Last Year
The CDC says influenza vaccinations prevented 79,000 flu hospitalizations and 3.2 million medical visits last year
Read more on healthnewsblog.com
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Source: HealthNewsBlog.com - December 13, 2013 Category: Health Medicine and Bioethics Commentators Tags: influenza-vaccine cdc Source Type: blogs
Virologists plan influenza H7N9 gain of function experiments
A group of virologists lead by Yoshihiro Kawaoka and Ron Fouchier have sent a letter to Nature and Science outlining the experiments they propose to carry out with influenza H7N9 virus.
Avian influenza H7N9 virus has caused over 130 human infections in China with 43 fatalities. The source of the virus is not known but is suspected to be wet market poultry. No human to human transmission have been detected, and the outbreak seems to be under control. According to the authors of the letter, the virus could re-emerge this winter, and therefore additional work is needed to assess the risk of human infection.
The research that ...
Source: virology blog - August 7, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Commentary Information aerosol transmission ferret fouchier gain of function GOF H5N1 h7n9 influenza kawaoka pandemic viral virus Source Type: blogs
Flu and the Y chromosome
Disease and death caused by influenza virus are greater in human females than in males. But disease is more common in males from birth through age 15, after which more females are affected. In mice, genetic variation in the Y chromosome controls susceptibility to influenza virus infection (link to paper). Increased susceptibility does not correlate with increased viral replication, but an expanded pathogenic immune response in the lungs.
A panel of mice (strain B6) with the Y chromosome from eleven different strains were used to determine the effect of infection. The mice fell into two groups with distinct high and low s...
Source: virology blog - May 12, 2017 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information disease susceptibility influenza mice sex viral virus viruses Y chromosome Source Type: blogs
