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Kermit ’ s urumi
Frogs don’t get flu (as far as I know) but their skin contains a peptide that inhibits the replication of influenza virus (link to paper). Frog skin contains host defense peptides (HDPs), part of the innate immune defenses of many species. They were first found in amphibians by Michael Zasloff, who, as part of his research, performed surgery on frogs and then returned them to an aquarium – which was not sterile. He wondered why the frogs always healed without signs of infection, which lead him to discover the antimicrobial peptides, called magainins, in frog skin. HDPs had been first discovered years earlier i...
Source: virology blog - July 27, 2017 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information amphibian antiviral compound defensin HDP host defense peptide influenza virus magainin urumin viruses Source Type: blogs

Candidate Sepsis Drug Could Prevent Flu Deaths
The 1918 Spanish flu killed up to 40 million people. The swine flu pandemic in 2009 killed an estimated 284,000. Now, scientists have discovered a substance that could help doctors save lives during future influenza pandemics. Eritoran, a compound under investigation as a sepsis drug, dramatically reduces deaths from influenza in mice. At the moment, [...]
Source: Biosingularity - May 5, 2013 Category: Medical Scientists Authors: Derya Tags: Biotechnology Source Type: blogs

Viruses on Time
Poliovirus recently made the cover of Time magazine. Prompted by a reader question, I searched the Time archive to find out if there have been other virology-themed covers. I found fifteen in all, depicting poliovirus (3), herpesvirus (1), HIV/AIDS (4), influenza (5), and SARS coronavirus (2) (I did not distinguish between US and international editions). The earliest virus-themed cover that I found has Jonas Salk on the cover of the 29 March 1954 issue. Behind Salk is an image of poliovirus particles, probably drawn from an electron micrograph. Salk’s field trial of inactivated poliovirus vaccine had begun in 1954, a...
Source: virology blog - January 21, 2013 Category: Virology Authors: Vincent Racaniello Tags: Information AIDS H5N1 herpesvirus HIV influenza poliovirus SARS coronavirus Time magazine cover viral virology Source Type: blogs

Family Sues After Dangerous Flu Vaccine Causes Child to Become Severely Brain Damaged
Conclusion After reading realms of information about the flu shot and the many tragic cases of vaccine-injured children, including the sad case of Saba Button, in my opinion, a child is far more likely to suffer serious side effects from the flu vaccine than from the flu itself. However, despite the many children who have become seriously ill after various flu vaccines, the governments around the world continue to portray the flu vaccine as safe and effective. Many flu vaccines still contain thimerosal, an ingredient that is said to have been removed from vaccines from as far back as 2007. [9] Since that time, this dangero...
Source: vactruth.com - July 9, 2013 Category: Health Medicine and Bioethics Commentators Authors: Christina England Tags: Christina England Top Stories Advisory Committee on Immunization Practices (ACIP) Afluria Brain Damage Centers for Disease Control (CDC) CSL Fluvax Thimerosal Vaccine Side Effects Source Type: blogs

TWiV 446: Old sins die hard
The TWiV hosts review an analysis of gender parity trends at virology conferences, and the origin and unusual pathogenesis of the 1918 pandemic H1N1 influenza virus. Click arrow to play Download TWiV 446 (68 MB .mp3, 112 min) Subscribe (free): iTunes, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Source: virology blog - June 18, 2017 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology 1918 pandemic gender parity H1N1 influenza virus Spanish flu viral virology conferences viruses Source Type: blogs

New, More Effective Flu Vaccine Delivered Using Dissolvable Microneedle Patch
Researchers at Georgia State University have developed a more effective way of delivering influenza vaccines thanks to a dissolvable microneedle array and a special formulation of the vaccine. The microneedle device is made of a biocompatible polymer...
Source: Medgadget - July 21, 2017 Category: Medical Devices Authors: Editors Tags: Medicine Pediatrics Source Type: blogs

This treatment could save your life – COVID-19 and Convalescent Plasma Therapy
Ajay Kohli Vinay Kohli Chitra Chhabra Kohli By CHITRA CHHABRA KOHLI MD, AJAY KOHLI MD, and VINAY KOHLI MD, MBA With a doubling time of cases estimated between 3 days within the U.S. and about 6 days globally (at the time of this writing) COVID-19 is demonstrating its terrifying virulence as it spreads across the world. What’s perhaps equally terrifying, if not more, is the absence of a known cure or treatment plan for COVID-19. While there has been a lot of attention focused on Hydroxychloroquine and Azithromycin, there has been debate on the scientific validity of these treatment options, either as thera...
Source: The Health Care Blog - March 30, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Patients Physicians Ajay Kohli Azithromycin convalescent plasma therapy coronavirus COVID-19 treatment hydroxychloroquine Pandemic Vinay Kohli Source Type: blogs

Half of Tamiflu prescriptions went unused during 2009 swine flu pandemic
Around 50% of the Tamiflu prescriptions issued during the influenza pandemic in 2009–10 went unused in England, a study by the UK’s Centre for Ecology & Hydrology (CEH) has found. The unused medication represents approximately 600,000 courses of Tamiflu at a cost of around £7.8m to the UK taxpayer. The finding, published online in the open access scientific journal Plos One, comes from the first study of its kind to use sewage water to estimate drug compliance rates. The study estimated usage of pharmaceuticals from large populations by sampling sewage and recovering the active component of Tamiflu, thus measuring d...
Source: PharmaGossip - April 17, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs

Dissolving Microneedle Vaccinations
Researchers recently demonstrated that a flu vaccine delivered using microneedles that dissolve in the skin can protect people against infection even better than the standard needle-delivered vaccine.The new microneedle patch is made of dissolvable material, eliminating needle-related risks. Not to mention the sea change it may mean for patients with severe needle anxiety!  I suspect this approach may also be more tolerable for many patients than oral and nasal vaccination methods. It is also easy to use without the need for trained medical personnel—making it ideal for use where healthcare resources are limited.“...
Source: The A and P Professor - July 14, 2015 Category: Physiology Authors: Kevin Patton Source Type: blogs

The Flu Is One Gift That We Don't Have To Keep On Giving For People With Cancer
  It's the holiday season, a time of reflection, celebration and for many, giving gifts. But there is at least one gift that no one wants to get, and certainly no one wants to give: the flu. And for people with cancer, and those they come in contact with, the flu can be a very serious event. For that reason and many more, people more than 6 months old-and especially those in contact with people who have serious illnesses like cancer-should get vaccinated against the flu. Too many of us think the flu is a minor inconvenience. But that is almost certainly because we confuse the typical cold or upper respiratory infectio...
Source: Dr. Len's Cancer Blog - December 17, 2013 Category: Cancer Authors: Dr. Len Tags: Cancer Care Environment Medications Prevention Survivors Treatment Vaccines Source Type: blogs

I Got Sick From My Flu Shot. No You Didn't.
The 2012-2013 flu season is turning out to be one of the worst seasons I've seen in the last ten years.  I started my professional hospitalist career in 2003.  I remember the West Nile outbreak shortly after that.  Everyone with a headache was getting a spinal tap to evaluate for viral meningitis.  And then there was the 2009  H1N1 scare a few years ago that turned out to be a bunch of nothing in my neck of the woods. I've seen a few cases of the flu during the winter flu season in years past, but nothing compared to what I'm seeing the last few weeks.  Hospitals have been aggressively asking...
Source: The Happy Hospitalist - January 8, 2013 Category: Internists and Doctors of Medicine Authors: Tamer Mahrous Source Type: blogs

Got Sick From Flu Shot? No You Didn't.
The 2012-2013 flu season is turning out to be one of the worst seasons I've seen in the last ten years.  I started my professional hospitalist career in 2003.  I remember the West Nile outbreak shortly after that.  Everyone with a headache was getting a spinal tap to evaluate for viral meningitis.  And then there was the 2009  H1N1 scare a few years ago that turned out to be a bunch of nothing in my neck of the woods. I've seen a few cases of the flu during the winter flu season in years past, but nothing compared to what I'm seeing the last few weeks.  Hospitals have been aggressively asking...
Source: The Happy Hospitalist - January 8, 2013 Category: Internists and Doctors of Medicine Authors: Tamer Mahrous Source Type: blogs

Not giving your child a flu shot? Read this letter from a grieving pediatrician first.
As of September 15, 85 children from 33 states, the District of Columbia and Puerto Rico have died due to infection with the flu during the 2015-2016 season. Piper Lowery, who was a healthy and vibrant 12-year-old girl died from H1N1 Influenza almost one year ago.  Her mother, Pegy Lowery, has gone public with her daughters’ story, to urge more parents to get flu shots for their children.  I would like to help her spread this message, because I was devastated by the death of Piper and I miss her beyond words.   Below is my reflection on my own grief as her pediatrician. My dearest Piper, I remember the day you were b...
Source: Kevin, M.D. - Medical Weblog - November 13, 2016 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/niran-s-al-agba" rel="tag" > Niran S. Al-Agba, MD < /a > Tags: Physician Pediatrics Source Type: blogs

The Flu Shot: It’s Not Just for Kids
The following post first ran on Huffington Post Healthy Living on September 23 and can be accessed here. The author is Liliana Losada Brown, PhD, Associate Director, Scientific Programs at the Society for Women’s Health Research. Think back to the last time you got a shot. Did the doctor cover the wound with a cartoon character-printed bandage and treat you to a lollipop? If so, you are way overdue for a flu shot — but that’s OK, we all are! Adults, children, pregnant women — everyone! –older than six months should get a flu shot every year. We all know the flu: the serious, contagious respira...
Source: Disruptive Women in Health Care - September 28, 2015 Category: Consumer Health News Authors: dw at disruptivewomen.net Tags: Men's Health Publc Health Women's Health Source Type: blogs