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TWiV 351: The dengue code
On episode #351 of the science show This Week in Virology, the Masters of the ScienTWIVic Universe discuss a novel poxvirus isolate from an immunosuppressed patient, H1N1 and the gain-of-function debate, and attenuation of dengue virus by recoding the genome. You can find TWiV #351 at www.twiv.tv.
Source: virology blog - August 23, 2015 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology attenuation codon bias codon pair bias dengue virus dinucleotide bias gain of function H1N1 immunosuppressed influenza virus kidney transplant poxvirus reversion translation vaccine viral Source Type: blogs

Silent Killers Amidst The Fast And The Furious
Attention to Ebola is important. The virus’s ability to easily cross regional and national borders makes it a significant threat to global health and national security. The swift and aggressive international response to the 2014 outbreak of the Ebola virus, which has killed at least 10,000 people in Liberia, Sierra Leone, and Guinea, has been laudable and has resulted in positive outcomes, such as reduced disease transmission and strengthened global health and coordination systems. For example, staff from the Centers for Disease Control and Prevention in the United States, including those from various divisions at the Na...
Source: Health Affairs Blog - May 7, 2015 Category: Health Management Authors: Karen R. Siegel, K.M. Venkat Narayan and Christine Hancock Tags: Costs and Spending Featured Global Health Public Health chronic disease Diabetes Ebola H1N1 Source Type: blogs

Seeking Past Lessons to Fight Flu
As the number of confirmed U.S. swine flu cases continues to rise, a host of questions have arisen about the lessons to be gleaned from two historical outbreaks, as well as how experts and the public should react.
Source: WSJ.com: Health Journal - April 29, 2009 Category: Consumer Health News Tags: FREE Source Type: blogs

Senolytic Treatment Fails to Improve Measures of the Immune Response to Influenza in Old Mice
At this point in the development of senolytic therapies to clear harmful, lingering senescent cells from aged tissues, it is more interesting to find an aspect of aging that isn't improved by removal of senescent cells than to continue adding to the long list of age-related conditions and dysfunctions that are meaningfully reversed by senescent cell clearance. Here, researchers show that measures of the immune response to influenza infection in mice are not improved followed treatment with the senolytic combination of dasatinib and quercetin. This is a perhaps surprising result, given the expectation based on evidence to d...
Source: Fight Aging! - July 12, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

A gameplan against this year’s flu
Did your team win this weekend? I hope so. It is so exciting when your team gets to throw up a “W” after their first contest. It gives all the fans hope for a successful and exciting season. Fall also is a time to cheer for our annual opportunity to protect our families against a predictably unpredictable opponent: influenza. That’s right. It’s time to defend against the flu by getting an annual flu vaccine. This season, your defensive coordinator (aka, your pediatrician) has a few “players” to choose from for your family’s best success. Continue reading ... Your patients are rating you online: How to respo...
Source: Kevin, M.D. - Medical Weblog - September 17, 2013 Category: Family Physicians Tags: Meds Medications Pediatrics Source Type: blogs

The flu vaccine is imperfect, but please get it anyways
This year’s flu vaccine, as you likely know, is taking a drubbing. The contention is that CDC flubbed, and didn’t get quite the right flu strains in the mix. That is apparently true, although more the “fault” of the influenza virus and its natively wily ways, than of the CDC. Either way, the drubbing is disproportionate to any flubbing. Continue reading ... Your patients are rating you online: How to respond. Manage your online reputation: A social media guide. Find out how.
Source: Kevin, M.D. - Medical Weblog - December 19, 2014 Category: Journals (General) Authors: Tags: Meds Infectious disease Primary care Source Type: blogs

TWiV 241: The ferret looks ill
On episode #241 of the science show This Week in Virology, Vincent, Alan, Rich and Kathy review how human placental trophoblasts confer viral resistance via exosome-mediated delivery of microRNAs, and isolation of the first human influenza virus in 1933. You can find TWiV #241 at www.twiv.tv.
Source: virology blog - July 14, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology exosome ferret H1N1 influenza miRNA placental trophoblast resistance viral virus WS Source Type: blogs

Weekly Posting of CDC Flu Reports to Resume
From the Robert Wood Johnson Foundation’s Public Health News Roundup: The U.S. Centers for Disease Control and Prevention (CDC) reported late yesterday that it has resumed analysis of influenza surveillance data and testing of influenza laboratory specimens collected during the 16-day government shut-down. An abbreviated FluView report summarizing the data for the most recent week (October 6-12) will be posted on Friday, October 18. At a later date, reports summarizing influenza surveillance data for September 22-October 5 will also be posted. Weekly Friday posting of the full FluView report for the 2013-2014 season ...
Source: BHIC - October 18, 2013 Category: Databases & Libraries Authors: Naomi Gonzales Tags: General Public Health Source Type: blogs

TWiV 343: The silence of the turnips
On episode #343 of the science show This Week in Virology, the TWiVerinoes discuss the potential for prion spread by plants, global circulation patterns of influenza virus, and the roles of Argonautes and a viral protein in RNA silencing in plants. You can find TWiV #343 at www.twiv.tv.
Source: virology blog - June 28, 2015 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology Ago Arabidopsis thaliana argonaute chronic wasting disease dicer epidemiology global circulation H1N1 H3N2 HC-Pro influenza virus plant potyvirus prion rna silencing rnai transmissible spongiform enc Source Type: blogs

TWiV 571: Piwi koalas
The League of Extraordinary Virologists celebrate the eradication of wild poliovirus type 3, and consider the effectiveness of an influenza vaccine produced in insect cells, and how small RNAs are protecting the Koala germline from retroviral invasion. Click arrow to play Download TWiV 571 (64 MB .mp3, 105 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes […]
Source: virology blog - October 27, 2019 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology baculovirus endogenous retrovirus Flu Flublock Flucelvax germline HA influenza influenza vaccine insect cell Koala koala retrovirus piRNA transposon viral viruses Source Type: blogs

Pharmalot… Pharmalittle… The Weekend Nears
And so, another working week is drawing to a close. Actually, we are rolling in the sidewalks momentarily, since this is an official day off here at the Pharmalot corporate campus. The schoolhouses are closed and we promised the short people we would spend some time with them. So we have arranged a few items for you and then will be on our way. As for you, we hope you do something fun, interesting or worthwhile – or all of the above – this weekend. After all, life is short. Might as well enjoy. And while you do, please be safe. See you soon… Feds Probe J&J Over Hip Implant Marketing (Associated Press...
Source: Pharmalot - February 22, 2013 Category: Pharma Commentators Authors: Ed Silverman Tags: Uncategorized Active Pharmaceutical Ingredients API Breast Cancer Dan Vasella Diet Pills Elan Flu Genentech Influenza JJ Johnson & Johnson Novartis Obesity Patient Adherence Roche Vaccines Vivus Source Type: blogs

Pharmalot… Pharmalittle… Good Morning
Good morning, folks, and how are you today? A spot of rain is falling on the Pharmalot corporate campus, where we are doing our best to energize the short people and tend to the usual early-in-the-day to-do list. Of course, the middle of the week only intensifies the need to move quickly. We trust you relate. So join us as we grab another cup of stimulation and dig in for another busy day. As always, here are some items of interest to help you along. Hope your day is smashing and do stay in touch… FDA OKs Pill For Post-Menopausal Sex Problems (Los Angeles Times) Allergan Settles Oklahoma Botox Case During Trial (Bloo...
Source: Pharmalot - February 27, 2013 Category: Pharma Commentators Authors: Ed Silverman Tags: Uncategorized Allergan AstraZeneca Biosimilars Botox Cystic Fibrosis Elan FDA Flu GlaxoSmithKline Hospira Influenza Menopause Merck Narcolepsy Osphena Pandemrix Royalty Pharma SFDA Shionogi Tredaptive Vertex Pharm Source Type: blogs

Dad Has the Flu and There’s a Baby at Home
By PHILIP LEDERER, MD At 6:30 AM, I kissed my 14-week-old son Joe on the forehead and headed off to work at the hospital. By 3 PM I was back in bed with a hacking cough and a fever.  I had influenza. As a doctor training in infectious diseases, I knew that the flu can be […]
Source: The Health Care Blog - March 4, 2015 Category: Consumer Health News Tags: THCB CDC CDC Foundation infectious diseases Lenzer Pediatrics Philip Lederer Tamiflu Source Type: blogs