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Gain of function research explained
The term ‘gain of function’ is perhaps one of the most misunderstood in the scientific lexicon. I would like to explain what the phrase means from the perspective of a scientist who has done gain of function research for the past 40 years. Gain of function (GoF) research gives an organism a new property or […]
Source: virology blog - September 10, 2021 Category: Virology Authors: Vincent Racaniello Tags: Basic virology avian influenza virus coronavirus COVID-19 ferret gain of function research GOF pandemic viral viruses Source Type: blogs

Making vaccination a condition of deployment in the health and wider social care sector
Department of Health and Social Care -The government is seeking views on whether or not to extend vaccination requirements to other health and care settings for Covid-19 and also for flu. The consultation closes on 22 October 2021.SurveyDepartment of Health and Social Care - consultations
Source: Health Management Specialist Library - September 9, 2021 Category: UK Health Authors: The King ' s Fund Library Tags: Covid-19 Workforce and employment Source Type: blogs

Selfish Much?
By KIM BELLARD In a week where we’ve seen the bungled Afghan withdrawal, had Texas show us its contempt for all sorts of rights, watched wildfires ravage the west and Ida wreak havoc on a third of the country, and, of course, witnessed COVID-19 continue its resurgence, I managed to find an article that depressed me further.  Thank you, Aaron Carroll. Dr. Carroll – pediatrician, long-time contributor to The New York Times, and now Chief Health Officer of I.U. Health — wrote a startling piece in The Atlantic: We’ve Never Protected the Vulnerable.  He looks at the resistance to public health measur...
Source: The Health Care Blog - September 7, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy health equity Kim Bellard Source Type: blogs

Fight Aging! Newsletter, August 30th 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out mo...
Source: Fight Aging! - August 29, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

“Claim Your Dose”: How Text-Message Reminders Can Increase Uptake Of COVID-19 Vaccines
By Emma L. Barratt Overcoming psychological barriers to vaccination remains a significant hurdle for COVID-19 vaccination efforts. Any given COVID-19 news feature will remind you that vaccine hesitancy is rife, especially in countries such as the United States. Compounding the issue further, even those who fully intend to get their jab can be forgetful or procrastinate, further hampering efforts to get shots in arms. As such, it’s vital to develop an effective toolbox to make it as effortless and appealing as possible for patients to book and turn up for their appointments. And though they may seem insignificant, ...
Source: BPS RESEARCH DIGEST - August 26, 2021 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Coronavirus Source Type: blogs

Here Come the Workplace Vaccine Religious Exemption Battles
Walter OlsonCompanies like Wal ‐​Mart, United Air Lines, and Tyson Foods have announced plans to require part or all of their workforce to be vaccinated against COVID-19. Many employee claims for religious exemptions are likely to follow. How are they likely to fare as a legal matter?InApril I wrote:Title VII, the federal employment discrimination law, forces an employer to accommodate employees ’ religious beliefs when it can do so without cost. For that reason, employees with religious objections to vaccination can ask employers to exempt them, and employers must at least consider the request. “Consider...
Source: Cato-at-liberty - August 25, 2021 Category: American Health Authors: Walter Olson Source Type: blogs

Age-Related Dysfunction in Cellular Metabolism Substantially Impacts the Immune System
Most of what to my eyes are less promising lines of research into the treatment of aging are focused on manipulation of cellular metabolism. These approaches, such as targeting the mTOR pathway, largely derive from the study of calorie restriction and the cellular response to stress that is brought on by lack of nutrients. Calorie restriction extends average and maximum life span considerably in short-lived species, up to 40% in mice, for example. It increases the efficiency of cellular maintenance processes and makes cells more frugal in other ways. The impact of aging is slowed, as molecular damage accumulates less rapid...
Source: Fight Aging! - August 23, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

“ Just a little scratch ”
Discussion I haven’t described the second experiment because of space, but go ahead and read it. Essentially they added some more participants, varied the procedure a little to reduce the memory burden on participants, and added a “medium” underprediction element into the process. The results showed similar outcomes – lower ratings of pain in both the “you won’t feel a thing” and the “it’ll hurt but not much” experiments, and yet again, less trust in the experimenter suggesting that it wouldn’t hurt. Lessons to learn? Think carefully about inflatin...
Source: HealthSkills Weblog - August 15, 2021 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Pain Psychology Research Health Therapeutic approaches Source Type: blogs

COVID ’s lab leak theory obscures zoonosis and progression
Even as COVID-19 is found in apes, big cats, minks, domestic cats, other small mammals, and now in U.S. deer, some don ’t want to let go of the insultingly simplistic “lab leak” theory. Do they really think the 1918 influenza and AIDS pandemics (or Ebola, MERS, and SARS ) needed lab mendacity to exist? WeRead more …COVID’s lab leak theory obscures zoonosis and progression originally appeared inKevinMD.com.
Source: Kevin, M.D. - Medical Weblog - August 7, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/martha-rosenberg" rel="tag" > Martha Rosenberg < /a > < /span > Tags: Conditions COVID-19 coronavirus Infectious Disease Source Type: blogs

A message from a patient to health care workers: Always remember your humanity
For those working in the health care profession, life has been a nightmarish existence for the past 18 months. COVID-19, originally billed as an illness no more severe than the flu, has devastated America and most other world countries. Loss of life due to the virus has been astounding, often attacking the most vulnerable ofRead more …A message from a patient to health care workers: Always remember your humanity originally appeared inKevinMD.com.
Source: Kevin, M.D. - Medical Weblog - August 6, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/michele-luckenbaugh" rel="tag" > Michele Luckenbaugh < /a > < /span > Tags: Patient Patients Source Type: blogs

Anti ‐​Vaxxers Turn to Big Government
Thomas A. FireyCOVID-19hospitalizations anddeaths are rising in the United States as the highly infectious Delta variant of the SARS-CoV-2 virus has becomethe dominant strain in the country. These serious cases arealmost entirely limited to people who are not vaccinated against the virus; for the vaccinated,infection rates are much lower and nearly all infections are no more troublesome than a cold or — at worst – a bout of the flu, and often go unnoticed altogether.COVID-19 causedat least11 percent of all U.S. deaths in 2020, making it thethird leading cause of death, behind only heart disease and cancer. So far in 20...
Source: Cato-at-liberty - August 2, 2021 Category: American Health Authors: Thomas A. Firey Source Type: blogs

Google ’ s Masterplan for Healthcare
With 7% of Google searches – or 70,000 per minute – being health-related, it was only a matter of time before the search giant aimed to be a healthcare giant. Google hasn’t been particularly shy at expressing these ambitions either. It purchased Fitbit for $2.1 billion and had a dedicated healthcare offshoot from its A.I. branch, Deepmind. In this new article series exploring the latest moves by tech giants into healthcare, we will look at recent developments coming from Google. Previous entries looked at the moves of Google’s competitors Amazon and Apple, and provided insights into the trends that those companies ...
Source: The Medical Futurist - July 27, 2021 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Digital Health Research Future of Medicine Future of Pharma Genomics Health Sensors & Trackers Portable Medical Diagnostics Security & Privacy AI genetics google Healthcare Innovation technolog Source Type: blogs

Vaccine associated myocarditis revisited with COVID-19 mRNA vaccines
When I had reviewed the topic of vaccine associated myocarditis for an editorial in the BMH Medical Journal in 2017, most of the cases were associated with small pox vaccination [1]. There were also reports of streptococcal pneumonia vaccine and influenza vaccine associated myocarditis. Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) used in the vaccine were also implicated in some cases [2,3]. While the large scale vaccination for small pox in an attempt to prepare for potential bioterrorism was the association in 2003 [4], COVID-19 mRNA vaccines are currently in the limelight for vaccine induced myocarditis...
Source: Cardiophile MD - July 22, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

Covid-19: preparing for the future - looking ahead to winter 2021/22 and beyond
This report warns that a mix of Covid-19, influenza, and the respiratory virus Respiratory Syncytial Virus, could push the NHS to breaking point this winter unless action is taken. The report urges policy makers and the NHS to prepare by expanding Covid-19 testing, increasing the speed and uptake of the Covid-19 vaccination, and strenthgened financial and staffing support.ReportThe Academy of Medical Sciences - news
Source: Health Management Specialist Library - July 15, 2021 Category: UK Health Authors: The King ' s Fund Library Tags: Covid-19 NHS performance and productivity Source Type: blogs

Moral injury: What is it, and how is it relevant post-COVID?
The COVID-19 pandemic has been unprecedented as such an event has not happened on such a global scale since 1919, with the Spanish Flu. At the beginning of the pandemic, we sometimes heard muzzled voices of health care providers who experienced sheer horror due to the quickly escalating demand for urgent care, ICU beds, andRead more …Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - July 7, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/tomi-mitchell" rel="tag" > Tomi Mitchell, MD < /a > < /span > Tags: Physician Psychiatry Source Type: blogs