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Hackers, Breaches And The Value Of Health Data: 2022 E-Book Update
As solutions like remote care are becoming the norm, 3D printing disrupts the normal supply chain and the number of life science studies on tools like artificial intelligence (A.I.) skyrocket, it’s become clear that we are not anticipating the digital health era; we are in the digital health era. This was to come sooner or later, but the pandemic accelerated the process by years. However, along with the enhanced healthcare landscape that digital health brings along, there is the pressing issue of privacy. To put it bluntly, there is no digital health without sacrificing a part of our privacy. The advanced techno...
Source: The Medical Futurist - August 11, 2022 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Covid-19 Digital Health Research E-Patients Future of Medicine Future of Pharma Genomics Health Sensors & Trackers Healthcare Design Healthcare Policy Personalized Medicine Security & Privacy Telemedicine & Smartphones amazon dev Source Type: blogs

The Future of 3D Printing Drugs In Pharmacies Is Closer Than You Think
3D printing drugs is not a fantasy anymore. Unbelievable shapes and any kind of drug can be fabricated with groundbreaking technology. The UK biotech company, FabRx believes it could even appear as a regular technique in hospitals and pharmacies for creating personalised drugs in specific doses within 5-10 years. In February 2022 the company announced they developed a technology allowing them to 3D print tablets in 7-17 seconds, a huge improvement from earlier. Print out starfish-shaped drugs for your child at home Somewhere in the 2030s: Annie was called by her daughter’s teacher that she had a high fever...
Source: The Medical Futurist - August 9, 2022 Category: Information Technology Authors: berci.mesko Tags: 3D Printing Future of Medicine Future of Pharma Healthcare Innovation Personalized medicine GC1 pharmacies 3d printed drugs personalized drugs Source Type: blogs

Fight Aging! Newsletter, August 8th 2022
In conclusion, aging research will benefit from a better definition of how specific regulators map onto age-dependent change, considered on a phenotype-by-phenotype basis. Resolving some of these key questions will shed more light on how tractable (or intractable) the biology of aging is. Does Acarbose Extend Life in Short Lived Species via Gut Microbiome Changes? https://www.fightaging.org/archives/2022/08/does-acarbose-extend-life-in-short-lived-species-via-gut-microbiome-changes/ Acarbose is one of a few diabetes medications shown to modestly slow aging in short-lived species. Researchers here take a ...
Source: Fight Aging! - August 7, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Nihilistic AAP Bronchiolitis Guidelines
​Not only has the COVID-19 pandemic killed millions of people, but it has also caused disruptions in every imaginable aspect of our lives. One has been the seasonality of other diseases like influenza and respiratory syncytial virus infection. RSV infection is typically a winter disease, but here we are in the summer months and our pediatric emergency department is flooded with infants infected with RSV.I expressed concern about the 2014 American Academy of Pediatrics bronchiolitis guidelines three years ago. (EMN. 2019;41[1]:31; http://bit.ly/2TlwNj9.) Those comments have proven to have real-life clinical releva...
Source: M2E Too! Mellick's Multimedia EduBlog - August 5, 2022 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Aging and the Severity of Inflammatory Infectious Disease Such as SARS-CoV-2
This article provides a pathophysiologic view of COVID-19 in older adults within the frame of inflammaging, with a focus on antiinflammatory treatments for acute and postacute disease. How can Biology of Aging Explain the Severity of COVID-19 in Older Adults Aging has been identified as one of the most relevant risk factors for poor outcomes in COVID-19 disease, independently from the presence of preexisting diseases. The COVID-19 mortality risk sharply increases for elderly subjects, as showed by the reports of China, Italy, and the United States. In particular, in Italy, case fatality rate for patient a...
Source: Fight Aging! - August 2, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Weekly Australian Health IT Links – 1 August, 2022.
Here are a few I have come across the last week or so. Note: Each link is followed by a title and a few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.General Comment-----Quite a lot this week – especially regarding the NBN and Labor trying to regain control of what it is actually for – service provision – and not making a huge profit – in their view. Love the new Minister has ambitions to be maximally photogenic and not a ‘techie’!Otherwise all sorts of fun things!-----https://www.ausd...
Source: Australian Health Information Technology - August 1, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Fight Aging! Newsletter, August 1st 2022
In this study, we used the recently released Infinium Mouse Methylation BeadChip to compare such epigenetic modifications in C57BL/6 (B6) and DBA/2J (DBA) mice. We observed marked differences in age-associated DNA methylation in these commonly used inbred mouse strains, indicating that epigenetic clocks for one strain cannot be simply applied to other strains without further verification. Interestingly, the CpGs with highest age-correlation were still overlapping in B6 and DBA mice and included the genes Hsf4, Prima1, Aspa, and Wnt3a. Furthermore, Hsf4, Aspa, and Wnt3a revealed highly significant age-associated DNA methyla...
Source: Fight Aging! - July 31, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
July 28, 2022 Edition-----Sadly the war drags on, Biden seems to be pretty impotent on most policy fronts and the US seems to be heading into a recession. Not good,In the UK the choosing the next PM is off and running as the country and Europe are cooling down after a heatwave (for them) of biblical proportions!In OZ Parliament is meeting which is when the rubber will really hit the road as a new virus wave runs out of control still! We need to do more to control it as we realise just how bad long COVID is!-----Major Issues.-----https://www.afr.com/policy/economy/how-a-nobel-laureate-got-australian-economists-offside-...
Source: Australian Health Information Technology - July 28, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

An Omics View of the Inflammation of Aging
Aging is characterized by chronic inflammation, disruptive of cell and tissue function, a sizable contribution to the onset and progression of all of the common age-related conditions. The causes of this inflammation are known at the high level, such as the increasing presence of senescent cells and damage-associated molecular patterns, such as DNA debris from dead and dying cells. At the detail level, the real of genomics, transcriptomics, proteomics, and the other omics, much remains to be cataloged. There is the hope that a full map of inflammation in aging would point out more and better regulatory or signal molecules ...
Source: Fight Aging! - July 26, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
The objective most consistent with recent operations is to conquer Luhansk, Donetsk, and Kherson, with a view to their eventual annexation and Russification. But not only are they some way from achieving that (w ith much of Donetsk still in Ukrainian hands and the Russia position in Kherson highly contested) it would also require an explicit Ukrainian surrender for it to serve as the basis for a declaration of victory. That will not be forthcoming.-----https://www.afr.com/world/europe/how-britain-giggled-its-way-into-crisis-20220710-p5b0giHow Britain giggled its way into crisisBoris Johnson has exposed the costs of Britain...
Source: Australian Health Information Technology - July 21, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Corruption in health care: when the mice mind the cheese
That the United States spends the most on health care is unsurprising. What’s questionable is paying so much for the worst health care system amongst high-income countries and being far behind many countries that could not be considered high-income by any stretch of the imagination. Other than doing brilliantly at mammograms and seasonal flu vaccines,Read more …Corruption in health care: when the mice mind the cheese originally appeared inKevinMD.com.
Source: Kevin, M.D. - Medical Weblog - July 17, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/anonymous" rel="tag" data-wpel-link="internal" > Anonymous < /a > < /span > Tags: Policy Public Health & Source Type: blogs

mRNA Vaccines: From Tackling Pandemic To Treating Cancer
The story of the multi-decade uphill battle Katalin Karikó and her fellow researchers fought to prove messenger RNA can viably be used in medicine is widely known today. In just as little as two years, the world has learned about mRNA technology and how fast it can react when the need arises holding almost unlimited promises in future applications. As always is the case with “instant hits” in science, the ride was actually very long and bumpy, but more on that later.  What is mRNA? In very simple terms: messenger ribonucleic acids (or mRNAs in short) are the body’s natural way to transport messages from o...
Source: The Medical Futurist - July 12, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Forecast Biotechnology Future of Medicine Nanotechnology cancer cancer research covid19 vaccine research HIV mRNA messenger RNA cancer vaccine malaria malaria vaccine HIV vaccine pancreatic cancer pancreatic cancer va Source Type: blogs

mRNA Vaccines: From Tackling A Pandemic To Treating Cancer
The story of the multi-decade uphill battle Katalin Karikó and her fellow researchers fought to prove messenger RNA can viably be used in medicine is widely known today. In just as little as two years, the world has learned about mRNA technology and how fast it can react when the need arises holding almost unlimited promises in future applications. As always is the case with “instant hits” in science, the ride was actually very long and bumpy, but more on that later.  What is mRNA? In very simple terms: messenger ribonucleic acids (or mRNAs in short) are the body’s natural way to transport messages from o...
Source: The Medical Futurist - July 12, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Forecast Biotechnology Future of Medicine Nanotechnology cancer cancer research covid19 vaccine research HIV mRNA messenger RNA cancer vaccine malaria malaria vaccine HIV vaccine pancreatic cancer pancreatic cancer va Source Type: blogs

FDA Wisely Permits Pharmacists to Prescribe Paxlovid
Jeffrey A. SingerWhen the Food and Drug Administration granted Emergency Use Authorization to the antiviral drugs Paxlovid and monupiravir in the beginning of this year, I co ‐​authored anoped in the New York Daily News, along with Josh Bloom of the American Council on Science and Health, complaining about, among other things, the FDA ’s requirement that a patient who tests positive for COVID must get a prescription from a doctor, nurse practitioner, or physician assistant to obtain the drug. For the drugs to be effective they must be started within five days of the start of COVID symptoms. Not ev...
Source: Cato-at-liberty - July 7, 2022 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs

Fight Aging! Newsletter, July 4th 2022
This study showed that centenarians had very specific changes in CD4+ T cell populations, which were manifested by an elevated Th17/Treg ratio in vivo, as well as a changed secretory phenotype. Although the T cells of centenarians cannot resist the aging-related expression of proinflammatory genes, their secretory phenotype was altered, explaining the relatively low level of inflammation in centenarians. These results suggested the presence of a mechanism to ameliorate inflammaging in centenarians. This may be achieved by reversing the imbalance of Th17/Treg cells and reducing pro-inflammatory cytokines. Longevit...
Source: Fight Aging! - July 3, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs