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Lack Of This Vitamin Linked To Brain Damage
Low levels have also been linked to Alzheimer's disease, as well as cancer and heart disease.
Source: PsyBlog | Psychology Blog - July 8, 2021 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Nutrition Source Type: blogs
Fight Aging! Newsletter, July 5th 2021
In conclusion, the findings suggest that DNAm GrimAge is a strong predictor of mortality independent of genetic influences.
Heart Failure Correlates with Increased Cancer Risk
https://www.fightaging.org/archives/2021/07/heart-failure-correlates-with-increased-cancer-risk/
Age-related disease results from the underlying cell and tissue damage that causes aging. Different people accumulate that damage at modestly different rates, the result of lifestyle choices and exposure to infectious disease. Thus the presence of a sufficient burden of damage to produce one age-related disease will be accompanied by a ...
Source: Fight Aging! - July 4, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Upregulation of NRF2 in Mice Slows Neural Stem Cell Decline in Middle Age, but Not In Later Life
Today's open access paper provides an interesting example of a mechanism that slows a facet of aging only in middle age, when tested in mice. Researchers found that upregulation of NRF2 expression in the brain via gene therapy had meaningful positive effects on neural stem cell function in middle age only. We might consider that any given aspect of cell behavior is governed by multiple overlapping regulatory networks, and thus it is quite possible to see a particular point of intervention work under some circumstances but not under others, depending on the state of the cell, its environment, and which regulatory systems ar...
Source: Fight Aging! - July 1, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Heart Failure Correlates with Increased Cancer Risk
Age-related disease results from the underlying cell and tissue damage that causes aging. Different people accumulate that damage at modestly different rates, the result of lifestyle choices and exposure to infectious disease. Thus the presence of a sufficient burden of damage to produce one age-related disease will be accompanied by a raised risk of other age-related conditions. The conditions themselves need not have any direct relationship with one another, but can be distinct outcomes of the same root causes. Here, however, researchers propose that heart failure may provoke increased cancer risk via inflammatory and ot...
Source: Fight Aging! - July 1, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Emerging Trends: Technology ’s Response To Alzheimer’s Disease
In our new series, Emerging Trends, we are looking at those technologies in digital health that are on a particular ‘hype cycle’ – technologies and solutions that currently stand out from the rest because of their novelty, timeliness, or greatness. These are solutions everyone’s talking about or the ones they should.
Technological solutions to cognitive decline and Alzheimer’s disease, in particular, are rising with increasing pipeline drug development, promising biomarkers, and more. Let’s jump right in.
Liza Marshall was “over the moon” when she said yes to the love of her life in a small cerem...
Source: The Medical Futurist - June 29, 2021 Category: Information Technology Authors: berci.mesko Tags: Forecast Lifestyle medicine Artificial Intelligence in Medicine E-Patients Future of Medicine Personalized Medicine Robotics Telemedicine & Smartphones alzheimer brain diagnosis digital digital health Healthcare Innovation me Source Type: blogs
The explosion of mental health apps raises substantial opportunities –and tough questions
In the eyes of the tech industry, mental health treatment is an area ripe for disruption.
In any given year, 1 in 5 adults in the U.S. experience a form of mental illness, according to federal estimates. And research indicates only about half of them receive treatment in a system that is understaffed and ill distributed to meet demand.
For tech startups looking to cash in on unmet need, that translates into more than 50 million potential customers.
Venture capital firms invested more than $2.4 billion in digital behavioral health apps in 2020 — more than twice the amount invested in 2019 — touting support or treatment ...
Source: SharpBrains - June 28, 2021 Category: Neuroscience Authors: Kaiser Health News Tags: Brain/ Mental Health Technology & Innovation anxiety BetterHelp brain-illness Brightside cerebral depression digital behavioral health FDA Food and Drug Administration Ginger health apps mental illness mental-health-treatment Source Type: blogs
Fight Aging! Newsletter, June 28th 2021
In conclusion, in our prospective community-based study, aging-related biomarkers were associated with measures of subclinical atherosclerosis cross-sectionally and with all-cause mortality prospectively, supporting the concept that these biomarkers may reflect the aging process in community-dwelling adults.
The Role of Aging Macrophages in Skin Inflammation
https://www.fightaging.org/archives/2021/06/the-role-of-aging-macrophages-in-skin-inflammation/
The immune system is complex and ages in complex ways, pressed by the lifetime burden of infection and rising levels of molecular damage that trigger many...
Source: Fight Aging! - June 27, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Drinking Straw Device for Hiccups Treatment
Researchers at the University of Texas Health Science Center at San Antonio have developed a device to treat hiccups. The drinking straw-like device allows a user to apply forceful suction to draw water into it, with subsequent swallowing triggering ...
Source: Medgadget - June 21, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Neurology Source Type: blogs
Fight Aging! Newsletter, June 21st 2021
This study showed that the leakage of this mitochondrial nucleic material may occur as a result of mitochondrial dysfunction, which may involve genetic mutations in genes encoding mitochondrial proteins or incomplete degradation of mitochondrial dsDNA in the lysosome - which is a 'degradation factory' of the cell. Upon the leakage into the cytoplasm, this undegraded dsDNA is detected by a 'foreign' DNA sensor of the cytoplasm (IFI16) which then triggers the upregulation of mRNAs encoding for inflammatory proteins."
Using a PD zebrafish model (gba mutant), the researchers demonstrated that a combination of PD-like ph...
Source: Fight Aging! - June 20, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Introducing Developmental Signaling into Adults in Order to Produce Regeneration
Is it possible to safely introduce developmental signaling characteristic of the developing embryo and fetus into an aged adult in order to spur greater regeneration of tissues? The past decades of work on embryonic stem cell therapies and induced pluripotent stem cell therapies, and the slow investigation of how most of these therapies produce their benefits via cell signaling, suggest that this goal is in principle possible. Similarly, research into species capable of proficient regeneration, such as salamanders and zebrafish, suggests broad similarities between the biochemistry of organ development and the biochemistry ...
Source: Fight Aging! - June 17, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
I ' m for it . . .
but it isn ' t going to happen, at least not this year. I got the following from the Drug Policy Alliance:Today, on the 50th anniversary of Nixon declaring the “war on drugs,” Reps. Bonnie Watson Coleman and Cori Bush haveofficially introduced the Drug Policy Reform Act, a bill to federally decriminalize ALL drugs that they unveiled earlier this week at the press conference the Drug Policy Alliance hosted. DPA has been a strategic partner on the development of this legislation and will be actively advocating for its passage in Congress. DPA ’s Executive Director, who is currentlytestifying before the House...
Source: Stayin' Alive - June 17, 2021 Category: American Health Source Type: blogs
Why “Radiopharmaceutical” Should be Part of your Healthcare Vocabulary
By JAY T. RIPTON
Not to sound too alarmist, but the radiopharmaceutical industry is on the verge of an explosion. But don’t worry; it’s not the type of explosion one often associates with nuclear materials… I love those movies too! It’s the beginning of a new wave of innovation for the diagnosis and treatment of certain cancers and other diseases.
This new radiopharmaceutical boom quite literally has the life sciences industry in a nuclear arms race of sorts, as companies like Y-mAbs, Novartis and others are pushing through clinical trials for the next blockbuster for the treatment and detection of hard-t...
Source: The Health Care Blog - June 14, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice jay t ripton nuclear medicine radiation oncology radiopharmaceuticals Source Type: blogs
Fight Aging! Newsletter, June 14th 2021
In conclusion, a number of high-income countries, changes in health expectancies over time have not kept pace with the growth in life expectancy. That is, people are living longer but disability and poor health are occupying an increasing proportion of later life. Our findings suggest that countries still need to make significant progress to achieve the WHO's Decade of Healthy Ageing goal of healthier, longer lives for all.
Progress on Understanding Why Human Growth Hormone Receptor Variants are Associated with Greater Longevity
https://www.fightaging.org/archives/2021/06/progress-on-understanding-why-human-gro...
Source: Fight Aging! - June 13, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Progress on Understanding Why Human Growth Hormone Receptor Variants are Associated with Greater Longevity
A few years back, researchers noted that a common growth hormone receptor gene variant was associated with greater life expectancy in humans. There was some theorizing as to possible mechanisms at the time, following the usual paths for anything that touches on growth hormone or its receptor. In short-lived mammals such as mice, loss of function in growth hormone or its receptor produces small body size and increased healthy longevity. The present record for mouse longevity is held by a growth hormone receptor knockout lineage. In humans, members of the small Laron syndrome population exhibit an analogous disruption of gro...
Source: Fight Aging! - June 11, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, June 7th 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - June 6, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
