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Smoking tied to more aggressive prostate cancer
If you’re a smoker looking for another reason to quit, consider this: in addition to raising your risk of heart and lung disease, as well as cancers of the bladder and kidney, smoking could boost the odds that you will develop aggressive prostate cancer that metastasizes, or spreads through your body. That’s according to research published by an Austrian team in 2018.
The evidence connecting tobacco use with prostate cancer (which tends to grow relatively slowly) isn’t as strong as it is for other smoking-related diseases. Researchers first detected the link only after pooling data from 51 studies that enrolled over ...
Source: Harvard Health Blog - November 26, 2018 Category: Consumer Health News Authors: Charlie Schmidt Tags: Health Prostate Knowledge Risks and Prevention HPK Source Type: blogs
I Got My Whole Genome Sequenced. Here ’s What I Learned.
Dante Labs sent me their Full DNA whole genome sequencing package, and I went through a roller-coaster of feelings: I was excited to know every secret of my cells, but I was afraid to get to know my hereditary cancer risks and worried what I might find. As in my case, (scientific) curiosity usually overrides fear, I jumped into the unknown and I’m eager to share my results here.
Whole genome sequencing is available to anyone. So what?
The human genome is the blueprint for building a person. When the Human Genome Project was completed in 2006, and the DNA double spiral uncovered its secrets for the very first time, scient...
Source: The Medical Futurist - November 20, 2018 Category: Information Technology Authors: nora Tags: Biotechnology Genomics Medical Professionals Patients Personalized Medicine Policy Makers Dante Labs data DNA future genetic genome sequencing genomic data genomic testing Health health risks health science Healthcare I Source Type: blogs
PSA-based screening for prostate cancer: Interpreting the changing guidelines
Comparing the 2018 U.S. Preventive Services Task Force (USPSTF) recommendation statement on prostate cancer screening in the October 15th issue of American Family Physician with its previous recommendation, the first question family physicians ought to ask is: What new evidence compelled the USPSTF to move from recommending against PSA screening in all men to determining that there was a small net […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Source: Kevin, M.D. - Medical Weblog - November 8, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/kenneth-lin" rel="tag" > Kenneth Lin, MD < /a > Tags: Conditions Oncology/Hematology Primary Care Source Type: blogs
Fight Aging! Newsletter, November 5th 2018
In conclusion, weight cycling significantly increased life-span relative to remaining with obesity and had a similar benefit to sustained modest weight loss.
Support for Oxidized Cholesterol as a Primary Cause of Atherosclerosis
https://www.fightaging.org/archives/2018/11/support-for-oxidized-cholesterol-as-a-primary-cause-of-atherosclerosis/
In the paper I'll point out today, the authors provide evidence in support of the concept that it is specifically oxidized cholesterol that is the primary cause of atherosclerosis rather than the condition resulting from too much cholesterol in general. In atheroscl...
Source: Fight Aging! - November 4, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Recent Research into the Interaction of Exercise and Aging
Today's open access papers touch on aspects of the interaction between exercise and the pace of aging. People age at somewhat different rates, and for the vast majority of us lifestyle is a far greater determinant of that rate than our genes. Until such time as the clinical deployment of rejuvenation therapies is well underway, and in regions of the world sufficiently wealthy to have tamed the majority of infectious disease, it remains the case that our choices regarding our health, such as calorie restriction and exercise, are the most reliable means of improving life expectancy. The size of the effect is not enormous in ...
Source: Fight Aging! - November 2, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Investigators unveil metastatic prostate cancer ’s genomic landscape
Localized prostate cancer that is diagnosed before it has a chance to spread typically responds well to surgery or radiation. But when a tumor metastasizes and sends malignant cells elsewhere in the body, the prognosis worsens. Better treatments for men with metastatic prostate cancer are urgently needed. In 2018, scientists advanced toward that goal by sequencing the entire metastatic cancer genome.
The newly revealed genomic landscape includes not just the active genes that make proteins, but also the vast stretches of DNA in between them that can also be functionally significant. Most of the genomic alterations were str...
Source: Harvard Health Blog - October 29, 2018 Category: Consumer Health News Authors: Charlie Schmidt Tags: Living With Prostate Cancer Prostate Knowledge HPK Source Type: blogs
Microfluidic Chips to Diagnose and Characterize Cancer: Interview with Prof. Fatih Sarioglu, Georgia Tech
Research into microfluidic devices to aid in cancer diagnosis promises huge leaps in making diagnostics easier and faster. Much of this research is focused on chips that can trap circulating tumor cells (CTCs) which are present in blood samples. CTCs...
Source: Medgadget - October 24, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Exclusive Oncology Source Type: blogs
Prostate cancer screening campaigns are giving men the finger
Fifty years ago, in a golden moment of television comedy shows, Rowan & Martin’s Laugh-In program regularly featured “The Flying Fickle Finger of Fate” award. Wikipedia says it “recognized actual dubious achievements by public individuals or institutions.” Do a Google search. You’ll quickly see how popular this award became.
Yes, I’m dating myself by going back 50 years. But mine is the generation that often becomes obsessed with being given “the finger” by doctors for digital rectal exams (DRE) looking for prostate cancer.
And it is in that context that we propose to revive The Flying Fickle Fi...
Source: Kevin, M.D. - Medical Weblog - October 22, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/gary-schwitzer" rel="tag" > Gary Schwitzer < /a > Tags: Conditions Mainstream media Oncology/Hematology Source Type: blogs
A new option for immunotherapy in metastatic prostate cancer
Dividing cells face daunting challenges when replicating the billions of letters of DNA in their genomes. For instance, DNA letters in new cells can get mixed up, and then the affected genes don’t function correctly. To fix that problem, healthy cells can deploy so-called mismatch repair (MMR) genes that put scrambled DNA letters back in the correct order. But when those genes are themselves defective, then this repair system breaks down. And as a result, cells develop a progressive condition called microsatellite instability that leaves them vulnerable to cancer.
Those sorts of defects are shared by many different tumor...
Source: Harvard Health Blog - October 21, 2018 Category: Consumer Health News Authors: Charlie Schmidt Tags: Prostate Knowledge Treatments HPK Source Type: blogs
The Pacey Cuff Urethral Control Device: Interview with CEO and a Practicing Urologist
Pacey Medtech, based in Vancouver, Canada, has developed the Pacey Cuff, a urethral control device for urinary incontinence in men, post-prostate cancer treatment. Treating prostate cancer can sometimes lead to urinary incontinence, which can have si...
Source: Medgadget - October 18, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Rehab Urology Source Type: blogs
When diagnosing colon cancer isn ’t in a patient’s best interest
So much of life depends upon timing. Sure, we plan, but we know how much of our life’s events are unplanned and unexpected. So often, our jobs and our mates — two of our most defining accomplishments — are the result of a chance encounter or a random act. Life does not reliably proceed in an orderly manner.
This is often true in the medical profession. Here, physicians in our quest to seek out and squelch disease, often discover what would should have been left alone. For example, is discovering prostate cancer in an older man a true benefit if the tumor would have remained silent throughout the man’s life?...
Source: Kevin, M.D. - Medical Weblog - October 15, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/michael-kirsch" rel="tag" > Michael Kirsch, MD < /a > Tags: Conditions Gastroenterology Oncology/Hematology Source Type: blogs
What is a plant-based diet and why should you try it?
Plant-based or plant-forward eating patterns focus on foods primarily from plants. This includes not only fruits and vegetables, but also nuts, seeds, oils, whole grains, legumes, and beans. It doesn’t mean that you are vegetarian or vegan and never eat meat or dairy. Rather, you are proportionately choosing more of your foods from plant sources.
Mediterranean and vegetarian diets
What is the evidence that plant-based eating patterns are healthy? Much nutrition research has examined plant-based eating patterns such as the Mediterranean diet and a vegetarian diet. The Mediterranean diet has a foundation of plant-based foo...
Source: Harvard Health Blog - September 26, 2018 Category: Consumer Health News Authors: Katherine D. McManus, MS, RD, LDN Tags: Healthy Eating Source Type: blogs
When men struggle with treatment decisions
It usually starts with a phone call:
“Doc, can I come and talk to you about something?”
The “something” might be erectile difficulties or other side effect(s) from prostate cancer treatment. It might be confusion or indecision about what treatment to agree to. I always inform the caller that any of these issues are better resolved if their spouse/partner is present and then leave it at that. I can make referrals to a pelvic floor physiotherapist for the man who has incontinence issues. I work with social workers who can deal with financial challenges or applications for social assistance. There are always men who w...
Source: Kevin, M.D. - Medical Weblog - September 19, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/anne-katz" rel="tag" > Anne Katz, RN, PhD < /a > Tags: Conditions Oncology/Hematology Source Type: blogs
10 superfoods to boost a healthy diet
No single food — not even a superfood — can offer all the nutrition, health benefits, and energy we need to nourish ourselves. The 2015–2020 US Dietary Guidelines recommend healthy eating patterns, “combining healthy choices from across all food groups — while paying attention to calorie limits.”
Over the years, research has shown that healthy dietary patterns can reduce risk of high blood pressure, heart disease, diabetes, and certain cancers. Dietary patterns such as the DASH (Dietary Approaches to Stop Hypertension) diet and the Mediterranean diet, which are mostly plant-based, have demonstrated significant ...
Source: Harvard Health Blog - August 29, 2018 Category: Consumer Health News Authors: Katherine D. McManus, MS, RD, LDN Tags: Diet and Weight Loss Health Source Type: blogs
What ' s in a name?
From time to time I have commented on the controversies over cancer screening. Most people assume that screening is an unqualified good, that early detection of cancer saves lives. Whenever some panel proposes recommending less screening, we hear screaming and yelling from advocates who claim they are trying to " ration " health care to save money at the expense of people ' s lives.In fact,as a bunch of Australians and a Minnesotan explain in BMJ, there are a few conditions called " cancer " that you are better off not treating, or perhaps treating very conservatively. These include what is called ductal carcinoma in situ ...
Source: Stayin' Alive - August 13, 2018 Category: American Health Source Type: blogs
