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6 changes that could lower the risk of developing prostate cancer
After skin cancer, prostate cancer is the most common type of cancer diagnosed in people with a prostate. Some risk factors associated with prostate cancer can’t be mitigated. Those factors include older age, a family history of prostate cancer, and race (Black men have double the risk of developing prostate cancer compared to white men).Read more …6 changes that could lower the risk of developing prostate cancer originally appeared inKevinMD.com.
Source: Kevin, M.D. - Medical Weblog - July 7, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/miles-j-varn" rel="tag" data-wpel-link="internal" > Miles J. Varn, MD < /a > < /span > Tags: Conditions Oncology/Hematology Source Type: blogs
Cancer Survivors Exhibit a Significantly Higher Risk of Cardiovascular Disease
The dominant cancer therapies of chemotherapy and radiotherapy have not yet been replaced by immunotherapies for more than a handful of cancer types. These classes of therapy produce a significantly increased burden of senescent cells in patients; one of the goals of cancer therapy is to drive cancerous cells into senescence, those that cannot be killed. These additional senescent cells in turn accelerate the progression of degenerative aging. The advent of senolytic therapies to clear senescent cells from aged tissues will make a sizable difference to these patients. More effort should be undertaken today to enable patien...
Source: Fight Aging! - July 4, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
How IoT Medical Devices Save and Improve Lives
The following is a guest article by Erik Kling, Interim Head of IoT Americas at Vodafone Business.
IoT, or the Internet of Things, has transformed our homes with connected lights and smart appliances. It’s also revolutionized all areas of business, including manufacturing. Sensors connected to the internet can track goods throughout the supply chain — from sourcing materials to delivering completed products to consumers.
IoT technology has improved the way we live, but its most profound impact may be in healthcare, where it’s saving lives and improving health.
Before IoT revolutionized healthcare, doctors and care pr...
Source: EMR and HIPAA - June 23, 2022 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Clinical Health IT Company Healthcare IT IT Infrastructure and Dev Ops AED American College of Cardiology Connected Defibrillators Continuous Glucose Monitors CPAP Dr. Ami Bhatt Elliot Erik Kling Healthcare AI Source Type: blogs
Science Snippet: RNA ’s Remarkable Roles
RNA, though less well known than its cousin DNA, is equally integral to our bodies. RNA molecules are long, usually single-stranded chains of nucleotides. (DNA molecules are also made up of nucleotides but are typically double-stranded.) There are three major types of RNA, which are all involved in protein synthesis:
Messenger RNA (mRNA) is complementary to one of the DNA strands of a gene and carries genetic information for protein synthesis to the ribosome—the molecular complex in which proteins are made.Transfer RNA (tRNA) works with mRNA to make sure the right amin...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 18, 2022 Category: Research Authors: Matt Mills Tags: Cells Injury and Illness Cellular Processes RNA Science Snippet Source Type: blogs
Fight Aging! Newsletter, May 16th 2022
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - May 15, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Reviewing Mitochondria-Derived Peptides in Aging
Researchers have explored a number of mitochondria-derived peptides as a basis for treatments in the context of aging. These peptides are created from fragments of genes in the mitochondrial DNA, released from the cell, and appear to be involved in a range of mechanisms relevant to declining function in aging. Is it possible to supply such peptides as a therapy in order to produce benefits in an aged metabolism? A number of groups working towards that goal, on the basis of data in animal studies and humans patients.
The mechanisms that explain mitochondrial dysfunction in aging and healthspan continue to be studie...
Source: Fight Aging! - May 13, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Underfunding Research Of Female Health Leaves Huge Amounts Of Money On The Table
“Did you know that at least one-third of women have lower back pain before their periods every month, and yet, nobody seems to fully understand why?” – asked a Medical Futurist team member a little while ago. The question led to a discussion about the differences in research, funding and understanding of male-only and female-only health issues, and consequently, to this article.
It is a well-known fact that some diseases or conditions dominantly affect one gender or the other. There are the trivial ones, like prostate cancer or ovarian, cervical, uterine cancers. But there is a long list of diseases and condit...
Source: The Medical Futurist - May 12, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Future of Medicine Healthcare Policy Medical Education women female health under-reseached gender gap in healthcare Source Type: blogs
Fight Aging! Newsletter, May 2nd 2022
In this study, we tested the therapeutic potential of VHHASC and a newly generated VHH against murine ASC (VHHmASC) to target ASC specks in vitro and in vivo. We show that pre-incubation of extracellular ASC specks with VHHASC abrogated their inflammatory functions in vitro. Recombinant VHHASC rapidly disassembled pre-formed ASC specks and thus inhibited their ability to seed the nucleation of soluble ASC. Notably, VHHASC required prior cytosolic access to prevent inflammasome activation within cells, but it was effective against extracellular ASC specks released following caspase-1-dependent loss of membrane integrity, an...
Source: Fight Aging! - May 1, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Mcl-1 Inhibitors as a Novel Class of Senolytic
Researchers working with prostate cancer cells here show that senescent cancer cells depend upon Mcl-1 to prevent programmed cell death, a novel target with existing drugs that may prove useful as general purpose senolytics, able to clear senescent cells from tissues. Cancers are highly varied, and this would have to be tested against the more usual types of senescent cell present in the aged body. Even if only applicable in the context of some cancers, however, this is still a useful discovery. Cancer survivors have a significantly reduced life expectancy in large part because they suffer a greatly increased burden of cel...
Source: Fight Aging! - April 29, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Prostate cancer, sex drive, male menopause and conversations to have with your doctor
Americans are having less sex than ever before. Should we be worried? Ask your prostate. A 2022 study from the National Survey of Sexual Health and Behavior found that the rate of all types of sexual intercourse have declined from 2009 to 2018. While the authors speculate as to why this may be the caseRead more …Prostate cancer, sex drive, male menopause and conversations to have with your doctor originally appeared inKevinMD.com.
Source: Kevin, M.D. - Medical Weblog - April 21, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/kevin-charles-king" rel="tag" data-wpel-link="internal" > Kevin Charles King, MD < /a > < /span > Tags: Conditions Oncology/Hematology Source Type: blogs
Incontinence from Prostate Cancer Surgery Acceptable Trade-off for John T
John T's family history included a number of men who developed prostate cancer so when he started having issues with dribbling due to bladder leaks, he watched cautiously and eventually sought medical help. His doctor ordered several PSA tests over time and eventually, John began seeing a urologist. He was diagnosed with prostate cancer and had surgery that left him with incontinence issues. No one wants this result, but he's learned to live with his incontinence - with gratitude.
Read John T's story on Egosancares blog for inspiration if you or someone you love may be facing prostate surgery:
Discover the Differenc...
Source: Minding Our Elders - March 17, 2022 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
MRI-Guided Magnetic Seeds Heat and Destroy Tumors
Scientists at University College London have developed a highly targeted anti-tumor treatment. The approach involves guiding ferromagnetic thermoseeds to the site of a tumor using the magnetic fields generated by an MRI scanner. The magnetic seeds ca...
Source: Medgadget - February 4, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Neurosurgery Oncology Radiation Oncology Radiology Source Type: blogs
Fight Aging! Newsletter, October 18th 2021
In this study, we therefore analysed the influence of lithium treatment on lifespan and parameters of health during ageing in mice.
To determine the concentration of lithium suitable to be administered in a longitudinal ageing study, we first tested the effects of lithium chloride (LiCl) in doses from 0.01 to 2.79 g LiCl per kg chow. C57Bl/6J mice fed with 1.05-2.79 g/kg LiCL in the diet showed lithium plasma levels between 0.4 and 0.8 mM/l. While plasma levels to 0.4 and 0.8 mM/l are well tolerated by human patients, at doses above 1.44 g LiCl/kg, we observed an obvious dose-dependent polydipsia combined with a dis...
Source: Fight Aging! - October 17, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Exploring Mechanisms by Which Exercise Slows Cancer Progression
Cancer patients who exercise tend to do better than those who do not. While one cannot escape an established cancer via physical activity, one can modestly slow it down, it appears. Researchers here explore some of the mechanisms by which exercise can achieve this goal, focusing on muscle tissue signaling that both slows cancer cell growth and provokes greater immune system activity. The usual path forward for this sort of research, given a large enough effect size to be interesting, is to try to find a way to deliver additional signal proteins as a form of treatment. This might be achieved directly using recombinant prote...
Source: Fight Aging! - October 12, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Gregory Finds Double Incontinence Harder to Accept than His Muscular Dystrophy
Any number o diseases including those of muscles, nerves, and conditions (such as dementia) can cause incontinence. Due to the social stigma of adult incontinence, people who have these diseases not only suffer from their primary disease but from the "shame" that surrounds their incontinence. Gregory is just 36 but as his MD progresses it's his incontinence that bothers him the most - even more than his pain, He needs a caregiver who must handle his incontinence which increases his sense of humiliation exponentially. Gregory's story not only helps us understand that many younger people are incontinent, but we can se...
Source: Minding Our Elders - October 2, 2021 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
