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Total 543 results found since Jan 2013.

The FDA approval of 23andMe ’s BRCA test: What it means for you
The approval by the Food and Drug Administration of 23andMe’s BRCA test is bound to create a discussion about the merits and pitfalls of direct to consumer genetic testing for cancer risk. It is also going to add fuel to a growing fire about how we as a nation assess genetic risks for cancer, and whether society is prepared for what is inevitably going to become a genomic-influenced and informed culture of health. From my perspective, as someone who has given considerable thought to these questions over the past several years, there are no easy answers. The announcement was straightforward: the FDA approved a test t...
Source: Kevin, M.D. - Medical Weblog - March 18, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/j-leonard-lichtenfeld" rel="tag" > J. Leonard Lichtenfeld, MD < /a > Tags: Conditions Genetics Oncology/Hematology Source Type: blogs

FDA approves new drug for men at high risk of prostate cancer spread
A newly approved drug called apalutamide is giving hope to thousands of men confronting a tenacious problem after being treated for prostate cancer. Prostate-specific antigen (PSA) levels should plummet to zero after surgery, and to near zero after radiation therapy, but in some men, they continue rising even when there’s no other evidence of cancer in the body. Doctors typically respond to spiking PSA with drugs that block the production of testosterone, which is the male sex hormone that fuels prostate cancer. However, this type of medically induced castration, called hormonal therapy, doesn’t always reduce PSA. More...
Source: Harvard Health Blog - March 15, 2018 Category: Consumer Health News Authors: Charlie Schmidt Tags: Cancer Health Men's Health Prostate Health Source Type: blogs

Knowing when to screen … and when to quit
Follow me on Twitter @RobShmerling Let us sing the praises of good medical screening tests. These are the tests that can detect medical problems before they become untreatable and before they cause complications or even death. Even better are those screening tests that detect “predisease” — abnormalities that aren’t dangerous on their own but can lead to problems later. According to the US Preventive Services Task Force, relatively few screening tests are considered good enough to routinely recommend for adults, including mammography for breast cancer (women) Pap smear for cervical cancer (women) bone density test...
Source: Harvard Health Blog - March 1, 2018 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Cancer Health Prevention Screening Source Type: blogs

The Skeptical Oncologist
By BISHAL GYAWALI, MD Why conduct post approval studies at all? Atezolizumab previously received accelerated approval in second-line metastatic or advanced urothelial cancer based on response rates from a single arm trial. The results of post approval confirmatory phase 3 are now published and demonstrate that atezolizumab did not improve survival versus chemotherapy (11.1 v 10.6 months, HR 0.87, p = 0.41). The concept of accelerated approval is to grant early and conditional approval and access to drugs in diseases of unmet need, and that the decision to fully approve or revoke be made based on results of confirmato...
Source: The Health Care Blog - February 7, 2018 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs

Newer drugs are improving survival for men with metastatic prostate cancer
This study provides important information that men with advanced forms of prostate cancer are now living longer than they once did, sometimes years longer. Those of us who have been treating prostate cancer for decades appreciate this study’s fundamental finding that the improved longevity from newer cancer drugs is considerable.” The post Newer drugs are improving survival for men with metastatic prostate cancer appeared first on Harvard Health Blog.
Source: Harvard Health Blog - January 31, 2018 Category: Consumer Health News Authors: Charlie Schmidt Tags: Cancer Health Men's Health Prostate Health Source Type: blogs

What ’s the point of a perfect patient chart?
Last week I made a patient’s chart perfect. Not bragging, but ultimately it ended up being pretty easy, and I’ll explain how and why in a little bit. This was a patient I had not seen in several years, with a number of chronic medical problems, for which he had been taking less than optimal care of himself since I had seen him last. Here for a “checkup,” we talked about his health conditions and how he had been over the past few years. I got a little update on his family and all the things he had been up to, and then he and I — along with his wife, who was here with him for the appointment ...
Source: Kevin, M.D. - Medical Weblog - January 18, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/fred-n-pelzman" rel="tag" > Fred N. Pelzman, MD < /a > Tags: Physician Health IT Primary Care Source Type: blogs

Hospice Care is covered by Medicare and Most Other Insurance
Dear Carol: My dad has aggressive prostate cancer that has spread to his liver and bones. His oncologist isn’t very communicative and when I asked about hospice care he said that’s up to us. He told us that Dad won’t get better but that he can keep treating him if we want. The treatments make Dad miserable. If they won’t help, what’s the point? I feel strongly that Dad needs hospice care and have been trying to talk my mom into it but she’s dragging her feet. How do we go about getting the service? Which one do we choose? Will Mom have to go on Medicaid to get it paid for? This is her biggest fear. – ST...
Source: Minding Our Elders - January 14, 2018 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

What Is An Abnormal Test Result?
By ROBERT MCNUTT, MD Most teachers of evidence-based-medicine talk about tests as “positive, or negative”. A positive test is one in which the result of the test is abnormal; a negative test is one in which the test’s result is normal. A problem with this way of teaching about the value of test results is that often physicians and patients think there are only two possible test results, normal or not. However, test results are never just, “normal or abnormal”; test results may take on many values, not just two. , Researchers distinguish normal test results by performing the test in people who are ...
Source: The Health Care Blog - January 9, 2018 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized McNutt Negative Positive Testing Source Type: blogs

My descent into guideline fatigue syndrome (GFS)
It started slowly.  My former resident and present colleague, Terry Shaneyfelt first authored Are Guidelines Following Guidelines? The Methodological Quality of Clinical Practice Guidelines in the Peer-Reviewed Medical Literature This paper alerted us to the problem.  But guideline fever continued to rage.  Almost every specialty and subspecialty society decided that they needed to join the guideline movement.  They needed to tell us the RIGHT way to practice medicine. While I understood the problems of guidelines (I had found a 40 page guideline on cerumen), it had not yet become visceral.  Then the great pharyngitis...
Source: DB's Medical Rants - December 25, 2017 Category: Internal Medicine Authors: rcentor Tags: Medical Rants Source Type: blogs

Why Living in a Rich Country Can Give You Cancer
Shutterstock As a primary care physician, I have counseled thousands of patients to get cancer screening—blood tests to look for prostate cancer, mammograms to detect impalpable breast cancers, and colonoscopies to find precancerous colon lesions. I’ve even tried to find … Continue reading → The post Why Living in a Rich Country Can Give You Cancer appeared first on PeterUbel.com.
Source: blog.bioethics.net - December 22, 2017 Category: Medical Ethics Authors: Peter Ubel Tags: Health Care breast cancer cancer screening Peter Ubel syndicated Uncategorized Source Type: blogs

Screening: Do you follow guidelines or your gut?
The commentary below is meant to invoke meaningful discourse rather than incite an unpleasant argument. Less than a year ago, I heard Ben Stiller doling out kudos to his heroic doctor who diagnosed him with early-stage prostate cancer by using a simple, widespread screen. What was interesting was that Stiller was actually underage. What I mean is that the star was not of age to be screened, according to current prostate cancer screening guidelines (American Cancer Association’s guidelines). He was in his mid-forties. The guidelines are pretty straightforward. Men over the age of 50 can be screened after an informed c...
Source: Kevin, M.D. - Medical Weblog - December 13, 2017 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/dana-corriel" rel="tag" > Dana Corriel, MD < /a > Tags: Conditions Oncology/Hematology Source Type: blogs

Health Care Needs Its Rosa Parks Moment
BY SHANNON BROWNLEE On Wednesday, October 25, 2017 I was at the inaugural Society for Participatory Medicine conference. It was a fantastic day and the ending keynote was the superb Shannon Brownlee. It was great to catch up with her and I’m grateful that she agreed to let THCB publish her speech. Settle back with a cup of coffee (or as it’s Thanksgiving, perhaps something stronger), and enjoy–Matthew Holt George Burns once said, the secret to a good sermon is to have a good beginning and a good ending—and to have the two as close together as possible. I think the same is true of final keynotes after a...
Source: The Health Care Blog - November 22, 2017 Category: Consumer Health News Authors: Matthew Holt Tags: OP-ED Patients Physicians Lown Institute Overtreatment Right Choice Alliance Shannon Brownlee Society for Participatory Medicine Source Type: blogs

Re-structuring the patient-provider communication process to empower patients
This post is written in response to Ubel, Scherr and Fagerlin’s target article, “Empowerment Failure: How Shortcomings in Physician Communication Unwittingly Undermine Patient Autonomy” published in the November 2017 issue of The American Journal of Bioethics. by Susanne B. Haga, PhD Most professional organizations have recommended a shift towards greater patient empowerment and shared decision-making. The result has been a data dump: An increase in the amount of information disclosed to patients.  For example, discussion of a prostate cancer diagnosis may include the grading and scoring, followed by di...
Source: blog.bioethics.net - November 14, 2017 Category: Medical Ethics Authors: Blog Editor Tags: Featured Posts Health Care Informed Consent OPC professional ethics health community patient decison-making professionalism Source Type: blogs

Teaching Better Communication: A Bootcamp Experience
This post is written in response to Ubel, Scherr and Fagerlin’s target article, “Empowerment Failure: How Shortcomings in Physician Communication Unwittingly Undermine Patient Autonomy” published in the November 2017 issue of The American Journal of Bioethics. by Haavi Morreim, JD, PhD and Mark C. Bugnitz, MD Communication is one of the most important skillsets in healthcare. As Ubel et al. describe in their American Journal of Bioethics article so well, inadequate communication can effectively deprive patients of the medical path that best fits with their personal goals and values – potentially leavin...
Source: blog.bioethics.net - November 13, 2017 Category: Medical Ethics Authors: Blog Editor Tags: OPC Uncategorized Source Type: blogs

We heard you — incontinence affects men too. Here’s what you need to know
As men age, the simple act of urinating can get complicated. Prostate surgery often leaves men vulnerable to leakage when they cough, sneeze, or just rise from a chair. Or the bladder may become impatient, suddenly demanding that you find a bathroom right now. “Thousands of years ago, it was not as much of an issue,” observes Dr. Anurag Das, a urologist at Harvard-affiliated Beth Israel Deaconess Medical Center. “There were lots of trees, and you could just find one and go.” But tricky bladders can be whipped into shape. The first step is a careful assessment of what triggers those difficult moments. Often your doc...
Source: Harvard Health Blog - November 8, 2017 Category: Consumer Health News Authors: Matthew Solan Tags: Health Healthy Aging Incontinence Men's Health Prostate Health Source Type: blogs