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Vitamin D: Finding a balance
Over the July 4th weekend, my non-physician husband with a history of skin cancer tried to justify not wearing sunscreen in order to get some vitamin D. My husband, of course, has no idea how much vitamin D he needs or why, and I suspect he is not alone. Why do we need vitamin D? The easy answer is for bones. Vitamin D facilitates absorption of calcium and phosphate, which are needed for bone growth. Without sufficient vitamin D, bones become brittle (in children this is called rickets and in adults it is called osteomalacia) and break more easily. Vitamin D is likely beneficial for other parts of the body as well; studies...
Source: Harvard Health Blog - July 21, 2017 Category: Consumer Health News Authors: Emily S. Ruiz, MD, MPH Tags: Drugs and Supplements Health Prevention Source Type: blogs

The Messenger Also Matters: Value-Based Payment Can Support Outreach To Vulnerable Populations
With the proliferation of value-based payment initiatives and implementation of the Affordable Care Act’s (ACA’s) coverage expansions, states have had many opportunities in recent years to improve the health of vulnerable populations through health promotion, prevention, and care coordination. We believe value-based payment models can and must support accountable health care delivery systems in partnering with community-based “messengers” to engage vulnerable individuals in health education and promotion. We explore one such messenger program, ACCESS, a Brooklyn-based project of the Arthur Ashe Institute for Urban ...
Source: Health Affairs Blog - July 10, 2017 Category: Health Management Authors: Ruth C. Browne, Marilyn Fraser, Judith Killen and Laura Tollen Tags: Health Equity Medicaid and CHIP Population Health Arthur Ashe Institute for Urban Health New York New York State Social Determinants of Health value-based payment vulnerable populations Source Type: blogs

The Contribution of Decreasing Cancer Mortality to Gains in Life Expectancy
This study provides an assessment of the impact of improvements in cancer prevention and cancer therapies over the past few decades, based on observed changes in life expectancy. In the opinion of the authors, better prevention is the more important contribution to these results - which doesn't say much for the current high level strategy in cancer research aimed at production of better therapies, given the vast sums devoted to that industry. Because of its focus on cancer, an unusual life expectancy construct is used in this study, considering only ages 40 to 84; cancer has a very low incidence at younger ages, and the ri...
Source: Fight Aging! - June 29, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

10 Key Ideas from The Truth About Cancer
I don’t read many books on health. A while back, however, I came across The Truth About Cancer and decided to read it. I was interested in it because cancer is one of the top killers in the modern age. More personally, my mom passed away because of cancer. I also have two friends who passed away because of cancer at the young age of 32 and 33. I’m glad I read the book. Honestly, the content of the book is not what I expected. I expected a positive attitude toward popular cancer treatments like chemotherapy, radiation, and surgery. But the book is actually against them. It’s eye-opening for me. You might want to read ...
Source: Life Optimizer - June 29, 2017 Category: Consumer Health News Authors: Donald Latumahina Tags: Health Source Type: blogs

Men ’ s Health Month: Getting Back to the Basics
You know the type. The macho guy who’s rough, tough, go-it-alone, leader-of-the-pack, help-not-wanted. Macho man may put off seeing a doctor for a checkup – because he thinks he’s invincible, doesn’t get sick, it’s a waste of time, only for the weak. Physicians at the University of Maryland Medical Center say some men only give in when they have symptoms, when major treatments are required, or when preventive steps are more demanding. Even so, it’s never too late to start on the road to health. June, Men’s Health Month, is a great time to focus on preventable health problems and encourage early detection and ...
Source: Life in a Medical Center - June 28, 2017 Category: Universities & Medical Training Authors: UMMC Tags: Health Tips Heart/Cardiac Care heart health mens health Source Type: blogs

Exosomes, The Elusive Tiny Vesicles Produced by Cells, Have Lots of Potential for Medicine
Exosomes are tiny capsules (30-130 nanometers) produced by cells that seem to be involved in all sorts of processes within the body, but only lately have they been properly studied. Because these natural nanoparticles are involved in many different b...
Source: Medgadget - June 26, 2017 Category: Medical Devices Authors: Editors Tags: Nanomedicine Source Type: blogs

Don ’t Underestimate Patients
By GEORGE BERGER, PHD I was diagnosed with aggressive but localized prostate cancer at a major Dutch academic hospital. My parameters were PSA 29 or 31, Gleason sum 4 + 4, and stage T2c. Fortunately, there were no detectable distant metastases. The specialist drew a simple image of my urinary tract and told me I was excluded from brachytherapy, which I had never heard of before, because of the size of my prostate. I had to choose between external beam radiotherapy (EBRT) and radical prostatectomy (RP). How on Earth could I choose rationally while knowing so little about prostate cancer? However, I had studied maths and phy...
Source: The Health Care Blog - June 17, 2017 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized ADT Dutch Health Care System Gleason Prostate Prostate Cancer Sweden Source Type: blogs

Combining surgery, radiation, and hormonal therapy dramatically extends survival in men with advanced prostate cancer
In April, scientists reported encouraging results from a pilot study of men with metastatic prostate cancer, or cancer that has spread beyond the prostate gland. Long considered incurable, these advanced cancers are usually treated by giving men systemic drugs that target new tumors forming in the body. The scientists who led this new study took a more aggressive approach. In addition to giving systemic therapy, they surgically removed the prostate gland and affected lymph nodes, and also treated visible cancer in the bones with radiation. By throwing everything but the kitchen sink at these cancers, they achieved a stunni...
Source: Harvard Health Blog - June 14, 2017 Category: Consumer Health News Authors: Charlie Schmidt Tags: Cancer Health Prostate Health Source Type: blogs

Fight Aging! Newsletter, June 12th 2017
In this study, we focused on two pathways of cardiomyocytes or heart cells: the Hippo pathway, which is involved in stopping renewal of adult cardiomyocytes, and the dystrophin glycoprotein complex (DGC) pathway, essential for cardiomyocyte normal functions." Previous work had hinted that components of the DGC pathway may somehow interact with members of the Hippo pathway. The researchers genetically engineered mice to lack genes involved in one or both pathways, and then determined the ability of the heart to repair an injury. These studies showed for the first time that dystroglycan 1, a component of the DGC pathw...
Source: Fight Aging! - June 11, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Persuing ASCO 2017 - AKA Time for Lorazepam
Photo from ASCO Mediakit. © ASCO/Danny Morton 2017TheAnnual Meeting of the American Society of Clinical Oncology was last week. It ’s been my observation over the years that much of the best palliative-oncology and supportive-oncology research is presented at ASCO each year, before it’s actually published (if it ever gets published).  So I always dig through the palliative/EOL/supportive/psychooncology abstracts each year to see what ' s happening. Below is a gently annotated list of the abstracts that caught my eye the most, for your perusal and edification. Undoubtedly, these are my idiosyncratic choices, ...
Source: Pallimed: A Hospice and Palliative Medicine Blog - June 8, 2017 Category: Palliative Care Tags: ASCO cancer oncology pallonc research research issues rosielle WaPo Source Type: blogs

Reviewing What is Known of PTEN and its Longevity Effects
The PTEN gene shows up in a number of places in aging research, and today's paper is a review of what is known of its relevance to the field. To pick a few items, PTEN appears to be involved in some of the processes and pathways that control nutrient sensing, and is thus of interest to researchers attempting to recreate the beneficial effects of calorie restriction via pharmaceuticals. It is also involved in regeneration and cancer as a governor that prevents excessive cell growth. In this context, PTEN suppression has been shown to enhance nerve regrowth in mice, but of course there are other, adverse consequences to turn...
Source: Fight Aging! - June 6, 2017 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

An Update on the Work of Oisin Biotechnologies: Building Therapies for Aging, Cancer, and Other Conditions by Targeting Harmful Cells for Destruction
Oisin Biotechnologies is a creation of our core community of longevity advocates, researchers, philanthropists, and others. The present CEO, Gary Hudson, was one of the first donors to support the newly formed Methuselah Foundation fifteen years ago. The company's seed funding was provided by the Methuselah Foundation and SENS Research Foundation a few years ago. A number of people in the audience here, myself included, invested in the company early last year in order to support this initiative. The initial goal of development at Oisin Biotechnologies is the targeted destruction of senescent cells, a path to produce one of...
Source: Fight Aging! - June 5, 2017 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

AHRQ Decision Aids for Patients
The Agency for Healthcare Research and Quality (AHRQ) provides Decision Aids for patients with certain conditions to help them think about what is important to them when talking with their clinician about treatment options. Decision Aids on Lung Cancer Screening, Urinary Incontinence, Osteoporosis, and Prostate Cancer are available, along with patient handouts and other resources.  
Source: BHIC - May 24, 2017 Category: Databases & Libraries Authors: Patricia Devine Tags: General Source Type: blogs

Evidence-Based Policy Making? - Dumb Things Politicians Say About Health Care Policy
There have been multiple legislative attempts at major health care reform in the US.  Typically, such attempts feature considerable public debate, including speechs, congressional committee hearings, sometimes progressing to debates by the House and Senate.  (For example, see thisFrontline chronology of the proceedings up to the passage of the Affordable Care Act, aka " Obamacare, " in 2009.)  Usually the discussion includes some real experts on health care policy, and some real health care professionals, and at least appears to reference some data about medicine, health care, and health economics. Whether p...
Source: Health Care Renewal - May 23, 2017 Category: Health Management Tags: health care reform postmodernism Source Type: blogs