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Total 777 results found since Jan 2013.

The Prospects for Telomerase Gene Therapy as a Treatment for Heart Disease
Telomerase gene therapy is considered in some quarters to be a viable treatment for aging. Telomeres are the caps of repeated DNA sequences at the ends of chromosomes. They are an important part of the mechanism limiting the number of times that somatic cells in the body can divide, the Hayflick limit. A little telomere length is lost with each cell division, and short telomeres trigger cellular senescence or programmed cell death, halting replication. Stem cell populations use telomerase to lengthen their telomeres and thus self-renew to provide a continual supply of new somatic daughter cells with long telomeres to repla...
Source: Fight Aging! - February 12, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

What ’s in a number? Looking at life expectancy in the US
If you were to sum up the overall health of a nation in one single number, what would that be? At the top of the list, you would likely find average life expectancy — the total number of years, on average, that a person in a country can expect to live. Wars, famine, and economic crises are expected to lower life expectancy. Breakthroughs in science, strong economies, and behaviors like eating a healthy diet, exercising, and avoiding tobacco typically raise average life expectancy. An amazing rise, a surprising fall Between 1959 and 2014, the United States experienced an unprecedented increase in life expectancy, which ro...
Source: Harvard Health Blog - February 7, 2020 Category: Consumer Health News Authors: Scott Weiner, MD Tags: Addiction Health Health care disparities Men's Health Women's Health Source Type: blogs

The Smart Sleep Alarm Is The Holy Grail Of Health Tracking
No, I kid you not. There’s no Sir Not-Appearing-in-this-Film nor eloquent monologues about swallows, and not even a reference to hose-riding coconut mimicry. I’ve truly found the Holy Grail of health tracking and will share it with you today. Behold as the answer is… the smart sleep alarm! If you ask anyone I know, they’ll probably share how I reverently praise smart sleep alarms. By the end of this article, you will understand why this is the case. Don’t count sheep, your health depends on it When I was a baby, my parents used to sing me lullabies to lull me off to sleep. As for adults, peopl...
Source: The Medical Futurist - February 6, 2020 Category: Information Technology Authors: Prans Tags: Health Sensors & Trackers sleep digital health sensors sleep sensor digital health technologies smart alarm Source Type: blogs

Syncope and Prehospital Cath Lab activation -- What do you think?
A 61 y.o. male with a history of HTN and ETOH developed squeezing epigastric abdominal pain with associated vomiting and diaphoresis, followed by a syncopal episode which lasted about 10 seconds.When medics arrived, he denied any chest pain, shortness of breath, or palpitations prior to the syncopal episode.They recorded a prehospital ECG and diagnosed STEMI and activated the cath lab prehospital.I heard that a prehospital cath lab activation was on its way.The patient arrived and we viewed the prehospital ECG:There is ST elevation in V1 and V2There is ST depression in II, III, aVFThere is ST depression and T-wave inversio...
Source: Dr. Smith's ECG Blog - February 5, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs

The Social Context and Vulnerabilities that Challenge Health Care in the San Joaquin Valley of California
By ALYA AHMAD, MD Call it what you want, white privilege and health disparity appear to be two sides of the same coin. We used to consider ethnic or genetic variants as risk factors, prognostic to health conditions. However, the social determinants of health (SDOH) have increasingly become more relevant as causes of disease prevalence and complexity in health care. As a pediatric hospitalist in the San Joaquin Valley region, I encounter these social determinants daily. They were particularly evident as I treated a 12-year old Hispanic boy who was admitted with a ruptured appendix and developed a complicated abscess,...
Source: The Health Care Blog - February 4, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Health disparities Medical Practice Patients Alya Ahmad California health disparity health equity San Joaquin Valley SDoH Social Determinants of Health Source Type: blogs

Fight Aging! Newsletter, February 3rd 2020
In conclusion, this study suggests that epigenetic age acceleration is significantly associated with lung function in women older than 50 years. We hypothesised that this could be due to menopause. However, we have observed that menopause has minimal effect and therefore there is possibility of other unknown physiological factors at older age in females mediating the epigenetic age acceleration effect on lung function. While, it is still unknown what exactly epigenetic aging from DNA methylation measures, this study suggests it can be utilised as one of the important factors to assess women's lung health in old age. DNA me...
Source: Fight Aging! - February 2, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Are you getting enough sleep … or too much? Sleep and stroke risk
This study found an association between stroke risk and longer sleep, longer midday napping, or poor sleep quality. But an association is not the same as causation. Rather than longer sleep duration causing strokes, there are other possible explanations for the findings. For example, people who sleep more at night or nap more during the day may have other risk factors for stroke, such as: A higher incidence of depression. Excessive sleeping or poor sleep quality may be symptoms of depression, and prior studies have noted higher stroke rates among depressed individuals. A more sedentary lifestyle. Those who are not active ...
Source: Harvard Health Blog - January 29, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Hypertension and Stroke Sleep Source Type: blogs

Disrupting How We Detect Asthma & Hypertension | Edward Allegra, BioLum Sciences
BY JESSICA DAMASSA BioLum Sciences is introducing new chemistry that has the potential to completely change the way we test for respiratory illnesses, like asthma, and analyze blood samples to identify hypertension. CEO Edward Allegra talks through the science behind both their breath and blood tests, both of which are patent-pending and have the ability to completely bend the cost-curve when it comes to identifying and monitoring these two common chronic conditions. What’s next for the early-stage health startup? A range of applications to detect everything from COPD to lung cancer and more. Filmed at Bayer G...
Source: The Health Care Blog - January 28, 2020 Category: Consumer Health News Authors: Grishma Reddy Tags: Health Tech Jessica DaMassa WTF Health Asthma Bayer G4A Bayer G4A Signing Day BioLum BioLum Sciences Edward Allegra Hypertension Source Type: blogs

Premature Menopause Correlates with Greater Later Incidence of Chronic Disease
Undergoing earlier menopause is a sign of a greater burden of age-related damage and dysfunction, so it should not be surprising to see that this correlates with a greater incidence of chronic disease in the years thereafter. People with a greater burden of cell and tissue damage tend to exhibit all of the manifestations of aging earlier than their less damaged peers. These variations in damage burden and consequences from individual to individual are near all the results of lifestyle choices, particularly smoking, weight, and exercise, and environmental factors such as exposure to chronic viral infection. Genetics plays o...
Source: Fight Aging! - January 27, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Ten Tips for Aging with Depression
Major Depression — the clinical type — is not a normal part of aging. Though it can appear at any age, older adults are at an increased risk. The Centers for Disease Control and Prevention (CDC) distinguishes this condition from having “the blues” and likens it to other medical illnesses that are treatable, like diabetes or hypertension. Overwhelming sadness and anxiety can last for weeks at a time or much longer, with a wide range of other discouraging symptoms. Yet, there are things that can help.  Statistics tell us that later in life, at least one chronic disease will affect 80 percent of us. It natura...
Source: World of Psychology - January 24, 2020 Category: Psychiatry & Psychology Authors: Jan McDaniel Tags: Aging Depression depression risk Elderly seniors Source Type: blogs

The truth about fatty liver
The majority of doctors will tell you that there is nothing you can do to reverse fatty liver and that health problems such as cirrhosis and liver failure may be in your future that they will address with the awful “solution” of liver transplant. The truth is the opposite: fatty liver is easily and readily reversible in virtually everybody, provided you take action before irreversible changes take place and are given the right information and tools. In this video, I discuss the three basic phenomena that drive fat deposition, liver damage, and inflammation that lead to this condition: Carbohydrate consumption ...
Source: Wheat Belly Blog - January 23, 2020 Category: Cardiology Authors: Dr. Davis Tags: Open bowel flora carbohydrates carbs Inflammation NAFLD nash triglycerides undoctored wheat belly Source Type: blogs

Low Value Testing and Unmet Cascades
By ANISH KOKA, MD Mr. Smith has a problem.  He can’t see.  Even this cardiologist knows why.  The not so subtle evidence lies in the cloudy lens in front of his pupils.  He is afflicted with cataracts that obstruct his vision to the point he can’t really do his job refurbishing antique furniture safely.  His other problem is that he hates doctors. He hasn’t had reason to see one for more than a decade.  He’s 68, takes no medications, smokes a pack of cigarettes a day, and is a master of one word answers. He’s in my office because he needs a medical evaluation prior to his cata...
Source: The Health Care Blog - January 21, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients Physicians Anish Koka cardiology low-value testing Source Type: blogs

Long-Term Effect of Binge Drinking on the Body
Most people know about the damaging effects that binge drinking can bring to someone’s life. Loss of enjoyment of life, losing family relationships, financial and career struggles, homelessness, and legal consequences are just the tip of the iceberg. However, it can be more difficult to realize the long-term effect of binge drinking on the body, because you cannot always see it. Frequent binge drinking poses many dangerous health risks, and many of them can lead to death. Facts on Long-Term Effect of Binge Drinking on the Body For men, binge drinking is defined as consuming five or more drinks within about two hours, a...
Source: Cliffside Malibu - January 17, 2020 Category: Addiction Authors: Jaclyn Uloth Tags: Alcohol Alcohol Rehab Information Alcoholism alcohol abuse alcohol dependence alcohol treatment alcohol treatment center binge binge drinking Source Type: blogs

Fight Aging! Newsletter, January 13th 2020
In this study, we investigated the link between AF and senescence markers through the assessment of protein expression in the tissue lysates of human appendages from patients in AF, including paroxysmal (PAF) or permanent AF (PmAF), and in sinus rhythm (SR). The major findings of the study indicated that the progression of AF is strongly related to the human atrial senescence burden as determined by p53 and p16 expression. The stepwise increase of senescence (p53, p16), prothrombotic (TF), and proremodeling (MMP-9) markers observed in the right atrial appendages of patients in SR, PAF, and PmAF points toward multiple inter...
Source: Fight Aging! - January 12, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, January 6th 2020
Conclusion A great deal of progress is being made in the matter of treating aging: in advocacy, in funding, in the research and development. It can never be enough, and it can never be fast enough, given the enormous cost in suffering and lost lives. The longevity industry is really only just getting started in the grand scheme of things: it looks vast to those of us who followed the slow, halting progress in aging research that was the state of things a decade or two ago. But it is still tiny compared to the rest of the medical industry, and it remains the case that there is a great deal of work yet to be done at all...
Source: Fight Aging! - January 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs