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Advancing American Indian and Alaska Native Health Through Research, Training, and Engagement
American Indian and Alaska Native (AI/AN) populations have long experienced health disparities such as higher rates of diabetes, certain cancers, and mental health conditions than those of other Americans. One contributing factor in these disparities is underrepresentation of AI/AN populations in biomedical science—as study participants, researchers, and health professionals. Unfamiliarity with health care options and opportunities, coupled with a distrust of biomedical research resulting from unethical studies in the past, have exacerbated this underrepresentation. NIGMS-supported researchers, including Native scient...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - November 2, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Genes Injury and Illness COVID-19 Diseases Genomics Profiles Training Source Type: blogs

Weekly Overseas Health IT Links – 29th October, 2022.
This report presents CDC findings on telehealth use trends in 2021. It includes data from the National Health Interview Survey, a nationally representative household survey conducted throughout the year by the National Center for Health Statistics. -----https://www.usnews.com/news/health-news/articles/2022-10-13/women-older-adults-more-likely-to-use-telemedicine-in-2021Who Used Telemedicine in 2021?New data shows which groups have been most likely to use a health care option popular during the pandemic.By Christopher WolfOct. 13, 2022, at 12:01 a.m.More than 1 in 3 adults used telemedicine in the past year in 2021, ac...
Source: Australian Health Information Technology - October 29, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

I am stupid
Conclusion: Isaac Asimov is stupid(Sorry, no post yesterday because I was doing some heavy cerebral processing.)He ' d have been the first to admit it. All of us are susceptible to cognitive errors and biases. I ' d like to think that Asimov was less susceptible than most, but he must have had his own foibles. It ' s a constant struggle to be mindful and think straight. For my own part, I once had a romanticized view of the Chinese revolution, I was an anthropogenic climate change skeptic, and I entertained the likelihood that medical intervention, on balance, did more harm than good. (Viz Illich, Medical Nemesis.)&nb...
Source: Stayin' Alive - October 28, 2022 Category: American Health Source Type: blogs

Fight Aging! Newsletter, October 24th 2022
This study shows the uncoupling of lifespan and healthspan parameters (aerobic fitness and spontaneous activity) and provides new insights into SIRT3 function in CR adaptation, fuel utilization, and aging. HDL Level, Age, and Smoking are the Largest Determinants of Mortality Risk in Old People https://www.fightaging.org/archives/2022/10/hdl-level-age-and-smoking-are-the-largest-determinants-of-mortality-risk-in-old-people/ An interesting epidemiological study here stratifies the contributions of various metrics to mortality in later life, age 70 and older. The authors find that the largest effects arise ...
Source: Fight Aging! - October 23, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Notes from the Rejuvenation Startup Summit, Held in Berlin in October 2022
We presented recent results showing reversal of liver inflammation and fibrosis in NASH model mice, and noted that we're raising funds to start our clinical development program leading to human trials. Therapies to reverse atherosclerosis progression will follow shortly on the heels of this work on NASH. Robin Mansukhani of Deciduous Therapeutics discussed their approach to immune system modulation via small molecules, training invariant natural killer cells to attack senescent cells. The point was made that engaging the immune system may be a way to work around many of the present unknowns regarding senescent cell ...
Source: Fight Aging! - October 19, 2022 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

Fight Aging! Newsletter, October 17th 2022
This study investigated whether multimorbidity is associated with incident dementia and whether associations vary by different clusters of disease and genetic risk for dementia. The study used data from the UK Biobank cohort, with baseline data collected between 2006 and 2010 and with up to 15 years of follow-up. Participants included women and men without dementia and aged at least 60 years at baseline. The presence of at least 2 long-term conditions from a preselected list of 42 conditions was used to define multimorbidity. A total of 206,960 participants (mean age 64.1 years) were included in the final sample, of...
Source: Fight Aging! - October 16, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, October 10th 2022
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - October 9, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

TLC Todd-versations: Todd Linsky in Conversation with Dr. Alan Greene
Todd Linsky, a food and organic industry veteran, hosts the podcast Todd-versations. He interviews guests from around the globe — influencers, leaders, and innovators in their respective fields. In this episode, Todd and Dr. Greene discuss the pediatric roots of longevity, the importance of nutrition in health, Dr. Greene’s reasons for creating DrGreene.com, his next projects, and a whole host of side topics. Transcript of Todd-versation Podcast with Todd Linsky and Dr. Greene 0:00 this conversation is brought to you in part by Calavo Growers the family of fresh! 0:19 hey there everybody good ...
Source: Conversations with Dr Greene - October 6, 2022 Category: Child Development Authors: Alan Greene MD Tags: Dr. Greene's Blog Source Type: blogs

Fight Aging! Newsletter, October 3rd 2022
In conclusion, based on the analysis of proteomics and transcriptome, we identified four SRMs that may affect aging and speculated their possible mechanisms, which provides a new target for preventing aging, especially skin aging. A Popular Science Article on the State of Epigenetic Clocks https://www.fightaging.org/archives/2022/09/a-popular-science-article-on-the-state-of-epigenetic-clocks/ This popular science article is a good view of the present state of development and use of epigenetic clocks, covering the issues as well as the promise. Epigenetic age can be measured, with many different clocks ...
Source: Fight Aging! - October 2, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, September 19th 2022
Conclusion Use of the Khavinson peptides and melatonin in combination in this way, at this dose, negatively impacts the thymus, producing a reduction in active tissue and increase in atrophy to fatty tissue. The degree to which this atrophy occurred is greater than one would expect to take place over nine months of aging at this stage of life. Why did this outcome occur, given the animal studies showing thymic regrowth, and the studies showing reduced later life mortality following use of thymogen? We can only speculate. Firstly, the dose makes the poison, and the dosing here may have been too high, too frequ...
Source: Fight Aging! - September 18, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, September 12th 2022
Discussion of Present Drug Development to Target Senescent Cells Targeting Senescent Cells to Better Address Cancer and Consequences of Cancer Therapy Calorie Restriction Suppresses Generation of Immune Cells via Changes to the Gut Microbiome Arguing for an Expansion of the Hallmarks of Aging https://www.fightaging.org/archives/2022/09/arguing-for-an-expansion-of-the-hallmarks-of-aging/ The hallmarks of aging form a catalog of largely better studied changes in cells and tissues considered relevant, and possibly more important, in the onset and development of age-related degeneration and disease. This i...
Source: Fight Aging! - September 11, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Arguing for an Expansion of the Hallmarks of Aging
The hallmarks of aging form a catalog of largely better studied changes in cells and tissues considered relevant, and possibly more important, in the onset and development of age-related degeneration and disease. This is not the same thing as a list of causes of aging. A few of the hallmarks mostly likely are or include deeper causes of aging, or close to causes of aging. The hallmarks do overlap with the SENS description of aging as a set of root causes, forms of molecular damage that result from the normal operation of a youthful metabolism. Since the hallmarks of aging are not, and are not intended to be a list of cause...
Source: Fight Aging! - September 5, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Fight Aging! Newsletter, September 5th 2022
Conclusion Coupled with the animal data, and the existing human trial data for safety, the results here suggests that someone should run a formal, controlled trial of flagellin immunization in older people, 65 and over. The goal would be to see whether (a) this sort of outcome holds up in a larger group of people, and (b) there is a meaningful impact on chronic inflammation and other parameters of health that are known to be affected by the aging of the gut microbiome. The most interesting part of the data is perhaps the decline in microbial diversity, when considered against the gains elsewhere. Microbial dive...
Source: Fight Aging! - September 4, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Weekly Overseas Health IT Links –27th August 2022.
In this study, researchers gathered a diverse group of participants; 43 percent were Black, and 68 percent were women. They also considered factors such as age and insurance status when drawing conclusions.The study occurred through a clinical trial, where all participants were randomly assigned to have their next visit occur through either phone or video-based platforms. The central unit of measurement was visit satisfaction rate, reported on a ten-point scale. Researchers noted noninferiority data based on whether patient satisfaction between the telehealth methods exceeded a -15 percent margin.-----https://www.theverge....
Source: Australian Health Information Technology - August 27, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Fight Aging! Newsletter, August 15th 2022
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - August 14, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs