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Fight Aging! Newsletter, March 11th 2019
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
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Source: Fight Aging! - March 10, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Video of Investor Jim Mellon Presenting at Abundance 360 Summit 2019
Jim Mellon's Juvenescence venture is at present one of the few major venture organizations focused on approaches to treat aging as a medical condition. Mellon and his colleagues outlined their take on the field in a 2017 book, also called Juvenescence. We are fortunate in that he is among the first few high net worth individuals to both agree with the SENS philosophy of damage repair, and then, much more importantly, follow through in action as well as word. He is not just seeing a massive market opportunity in treating aging, though that is certainly there, but is doing this because he wishes to achieve the goal of radica...
Source: Fight Aging! - March 4, 2019 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Preventing cervical cancer: how a screening switch and HPV vaccination should cut cancer rates
Related items fromOnMedica Parents unsure of HPV vaccine for daughters Tackling obesity ‘must be made a national priority’ JCVI recommends universal HPV vaccination Maternity care better in some respects – but still many problems Obesity as cause of cancer set to overtake smoking
Source: OnMedica Blogs - March 3, 2019 Category: General Medicine Source Type: blogs
A Conversation with Marietje Schaake (Part I)
Marietje Schaake is a leading and influential voice in Europe on digital platforms and the digital economy. She is the founder of the European Parliament Intergroup on the Digital Agenda for Europe and has been a member of the European Parliament since 2009 representing the Dutch party D66 that is part of the Alliance of Liberals and Democrats for Europe (ALDE) political group. Schaake is spokesperson for the center/right group in the European Parliament on transatlantic trade and digital trade, and she is Vice-President of the European Parliament ’s US Delegation. She has for some time advocated more regulation and acco...
Source: Cato-at-liberty - February 19, 2019 Category: American Health Authors: Flemming Rose Source Type: blogs
Insurers Are Not Paying Enough For HPV Vaccines – And Our Kids Are Paying The Price
The HPV vaccine saves lives. It does so by reducing a person’s chance of being infected by the human papilloma virus, a virus that causes a whole range of cancers including, most importantly, cervical cancer. Vaccinate your teenage daughter against … Continue reading →
The post Insurers Are Not Paying Enough For HPV Vaccines – And Our Kids Are Paying The Price appeared first on PeterUbel.com.
Source: blog.bioethics.net - February 19, 2019 Category: Medical Ethics Authors: PeterUbel.com Tags: Health Care Health & Well-being health policy Peter Ubel syndicated Uncategorized Source Type: blogs
Everyone Has a Part to Play in Ending Vaccine Hesitancy
Felicia D. Goodrum Sterling
Heidi L. Pottinger
By FELICIA D. GOODRUM STERLING, PhD and HEIDI L. POTTINGER, DrPH, MPH, MA
The measles outbreak in Washington state this week has brought new attention to the anti-vaccine movement. In fact, the World Health Organization recently identified “vaccine hesitancy” as one of top threats to global health. In the US, the number of unvaccinated children has quadrupled since 2001, enabling the resurgence of infectious diseases long-since controlled. In fact, the WHO claims a staggering 1.5 million deaths could be prevented worldwide by improved vaccination rates.
Amidst the medi...
Source: The Health Care Blog - February 12, 2019 Category: Consumer Health News Authors: matthew holt Tags: Patients Felicia Goodrum Sterling Global Health Heidi L. Pottinger public health The OpEd Project vaccines Source Type: blogs
Freedumb
Specifically, the freedumb to let your kids get seriously ill. I believe I may have mentioned previously that all but three states allow parents to opt out of mandatory vaccination for their children to attend school. Most of these allow only " religious " exemptions but of course anybody can claim to have one. Other just allow for " personal beliefs, " which means there isn ' t actually any mandate at all.It is a basic principle of medical ethics that people have to give informed consent for medical interventions. However, the situation with children is different. We don ' t let people starve or poison their children out ...
Source: Stayin' Alive - January 29, 2019 Category: American Health Source Type: blogs
Fight Aging! Newsletter, January 28th 2019
In this study, we show that calorie restriction is protective against age-related increases in senescence and microglia activation and pro-inflammatory cytokine expression in an animal model of aging. Further, these protective effects mitigated age-related decline in neuroblast and neuronal production, and enhanced olfactory memory performance, a behavioral index of neurogenesis in the SVZ. Our results support the concept that calorie restriction might be an effective anti-aging intervention in the context of healthy brain aging.
Greater Modest Activity in Late Life Correlates with Lower Incidence of Dementia
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Source: Fight Aging! - January 27, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
We have a shot at preventing cervical cancer
Many people think eradicating cancer is unattainable. But for cervical cancer, we are well on our way to doing just that. Cervical cancer was once the leading cause of death in women in the U.S. But we are on the cusp of vanquishing this disease thanks to regular pap screening and a vaccine that protects […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Source: Kevin, M.D. - Medical Weblog - January 25, 2019 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/lisa-n-abaid" rel="tag" > Lisa N. Abaid, MD, MPH < /a > < /span > Tags: Meds OB/GYN Source Type: blogs
A Recent Update on the Use of Immune Ablation and HSCT to Treat Autoimmunity
For more than twenty years now, Richard Burt's research teams have been working on the treatment of autoimmunity through the destruction and recreation of the immune system. Autoimmunity is a malfunction in the self-tolerance of immune cells, leading them to attack patient tissues. The malfunction is entirely contained in the immune system, so if the immune system is destroyed and replaced, the autoimmunity stops. If the genesis of autoimmunity is happenstance, an unfortunate one-time accident, then this is a cure. But if autoimmunity has a trigger outside the immune system in a given patient, it will return after some per...
Source: Fight Aging! - January 22, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
A Bizarre Claim of Right to Try
By ARTHUR CAPLAN, KELLY MCBRIDE FOLKERS, and ANDREW MCFADYEN
A patient with glioblastoma recently received an experimental cancer vaccine at the University of California, Irvine. Notably, this is being hailed as the first case of someone utilizing the Right to Try Act of 2017. ERC-USA, a U.S. subsidiary of the Brussels-based pharmaceutical company Epitopoietic Research Corporation, says it provided its product, Gliovac, to the patient at no cost. The vaccine is currently undergoing Phase II clinical trials. A handful of people in Europe have received access to it through “compassionate use.” This patient did not qual...
Source: The Health Care Blog - January 18, 2019 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Patients Politics Trump's Health ANDREW MCFADYEN Arthur Caplan Donald Trump FDA KELLY McBRIDE FOLKERS pharmaceuticals Right to Try Act Source Type: blogs
Fatty liver disease: What it is and what to do about it
Non-alcoholic fatty liver disease (NAFLD), a condition of extra fat buildup in the liver, is on the rise — it now affects roughly 20% to 40% of the US population. It usually doesn’t cause any symptoms, and is often first detected by accident when an imaging study (such as an abdominal ultrasound, CT scan, or MRI) is requested for another reason. A fatty liver may also be identified on an imaging test as a part of investigating abnormal liver blood tests. NAFLD is intimately related to conditions like diabetes and obesity. It’s also linked to an increased risk of cardiovascular disease. Understanding NAFLD and its cau...
Source: Harvard Health Blog - January 10, 2019 Category: Consumer Health News Authors: Wynne Armand, MD Tags: Digestive Disorders Health Source Type: blogs
Exceptional longevity: why some people live to be more than 100-year old
Interventions that promote longevity, remembered by mnemonic:DEEP purple - “eat colorful plant foods:Dietary modification,Exercise, activeEngagement,Purposeful living (click here toenlarge the image).Based on a Mayo Clinic Proceedings article (https://www.mayoclinicproceedings.org/article/S0025-6196(18)30792-4/):Exceptional Human Longevity: the oldest old have an extreme phenotype of delayed onset of age-related diseases and/or resistance to lethal illnesses occurring earlier in life.Centenarians have delayed onset of chronic diseasesDuring the span of human history the likelihood of living from birth to age 100 rose fro...
Source: Clinical Cases and Images - Blog - December 25, 2018 Category: Universities & Medical Training Tags: Lifestyle Longevity Mayo Clinic Source Type: blogs
Fight Aging! Newsletter, December 24th 2018
In conclusion, we found a gradient of increasing blood pressure with higher levels of BMI. The fact that this gradient is present even in the fully adjusted analyses suggests that BMI may cause a direct effect on blood pressure, independent of other clinical risk factors.
PRRX1 as a Possible Point of Control for Remyelination
https://www.fightaging.org/archives/2018/12/prrx1-as-a-possible-point-of-control-for-remyelination/
Researchers here outline what is possibly a new point of intervention in the processes that maintain the myelin sheath that wraps nerves. This sheath is vital to the correct operatio...
Source: Fight Aging! - December 23, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, December 17th 2018
In this study, we found that TNF-α resulted in an impairment of autophagic flux in microglia. Concomitantly, an increase of M1 marker expression and reduction of M2 marker expression were observed in TNF-α challenged microglia. Upregulation of autophagy via serum deprivation or pharmacologic activators (rapamycin and resveratrol) promoted microglia polarization toward M2 phenotype, as evidenced by suppressed M1 and elevated M2 gene expression, while inhibition of autophagy with 3-MA or Atg5 siRNA consistently aggravated the M1 polarization induced by TNF-α.
Moreover, Atg5 knockdown alone was sufficient to trigger...
Source: Fight Aging! - December 16, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
