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Looking Back At Today ’s Healthcare In 2060
I receive many questions after my talks and on my online channels about the not yet visible future. People want to know what healthcare will be like in the next decades. But throwing around predictions will not help us design a better healthcare. Although showing a utopian future of healthcare might do so.
On a chilly October afternoon in 2060,
after having watched the leaves falling off the trees in our garden for too long to get bored, my beautiful and overtly curious grandchild, Nina, came to me and started asking me questions.
She pointed at one of the many CubeSensors in the living room – small,...
Source: The Medical Futurist - April 26, 2022 Category: Information Technology Authors: berci.mesko Tags: Healthcare Design Science Fiction future Medical education Medicine Personalized medicine technology gc4 Source Type: blogs
Spherical Nucleic Acid Vaccine Uses Structural Design to Improve Efficacy
A team at Northwestern University created a new type of nanoparticle-based vaccine that employs structure-function relationships during the design phase to maximize efficacy. Called a spherical nucleic acid (SNA) vaccine, the technology consists of g...
Source: Medgadget - April 4, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Nanomedicine Public Health Source Type: blogs
Weekly Overseas Health IT Links – 2nd April, 2022.
Here are a few I came across last week. Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment. ----- https://ehrintelligence.com/news/epic-healthy-planet-increased-patient-adherence-to-preventive-care Epic Healthy Planet Increased Patient Adherence to Preventive Care Epic Healthy Planet used EHR data to determine care gaps for older high-risk patients, resulting in greater patient adherence to preventive care services such as cancer screening and vaccinations...
Source: Australian Health Information Technology - April 2, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Weekly Overseas Health IT Links – 26th March, 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.-----https://mhealthintelligence.com/news/55-of-telehealth-providers-frustrated-with-overblown-patient-expectations55% of Telehealth Providers Frustrated With Overblown Patient ExpectationsProviders also cited their ability to provide quality care and technical difficulties as among their top frustrations with telehealth, a new survey shows.ByAnuja VaidyaMarch 18, 202...
Source: Australian Health Information Technology - March 26, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
The (sort of, partial) Father mRNA Vaccines Who Now Spreads Vaccine Misinformation (Part 1)
By DAVID WARMFLASH, MD
Robert W. Malone, MD MS, is a physician-scientist who will live in infamy, thanks to the Joe Rogan Experience Podcast boosting his visibility this past December regarding his criticism of COVID-19 vaccines, particularly the mRNA vaccines (Moderna and Pfizer-BioNTech). Subsequently, Malone was banned from Twitter, which further boosted his celebrity status. Describing himself as the inventor of mRNA vaccine technology, he has been reaching a growing number of people with a narrative that makes COVID-19 vaccination sound scary. We cannot embed clips from the Rogan interview, which lasted about three...
Source: The Health Care Blog - March 17, 2022 Category: Consumer Health News Authors: matthew holt Tags: COVID-19 Health Policy antivaxxer COVID-19 vaccine David Warmflash Joe Rogan Robert Malone Source Type: blogs
How Do We Know If COVID Is Over?
Is it the end of COVID? – we hear this very question more and more often these days. This topic has been analysed over and over in the past two years, I also wrote about it more than once. Here, at the beginning, we outlined possible scenarios on how the pandemic will develop. By now we can determine that we ended up somewhere between #2 and #3.
We also discussed how widespread vaccination is the way to go, and how it will contribute to getting back our lives.
The speculation on finally getting over it is not surprising. It is in line with recent reports, and the discussion about the pandemic entering the endem...
Source: The Medical Futurist - March 15, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Covid-19 public health covid19 pandemic endemic end of covid Source Type: blogs
What the Pandemic Taught Us About Value-based Care
By RICHARD ISSACS
You’ll recall that we ran a long piece (pt 1, pt 2) about Medicare Advantage from former Kaiser Permanente CEO George Halvorson earlier this year. Here’s a somewhat related piece from the current head of the Permanente Medical Group about what actually happened there and elsewhere during the pandemic–Matthew Holt
The COVID-19 pandemic has provided important lessons regarding the structure and delivery of health care in the United States, and one of the most significant takeaways has been the need to shift to value-based models of care.
The urgency for this transformation was cle...
Source: The Health Care Blog - February 17, 2022 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice Physicians Kaiser Permanente Medicare Advantage Pandemic Richard Isaacs value-based care Source Type: blogs
Rationing and Indication
I ' ll let y ' all in on a secret: I ' m writing a book. It ' s basically everything you need to know, as a citizen, taxpayer, consumer of medical services, friend or family member of consumers of medical services, and just plain person, about health and health care in the U.S. For some reason I haven ' t much connected the work on the book to this blog -- there is tons of materials I could have lifted from my book chapters and posted here for your delectation and delight. I ' m not sure why I haven ' t been doing that, and maybe I will.Anyway, the previous post creates an occasion to discuss a matter that seems pretty obv...
Source: Stayin' Alive - January 31, 2022 Category: American Health Source Type: blogs
Temporary Chimeric Antigen Receptor T Cells Produced in the Body via mRNA Gene Therapy
Chimeric antigen receptors applied to T cells, known as CAR-T therapies, are expensive. Isolating a patient's T cells, culturing them, engineering them, and then returning them to the body is an undertaking, particularly when it must be carried out with the very high level of reliability and quality control required by regulators. CAR-T therapies do well in attacking many types of cancer, but can have side-effects due to the lasting presence of engineered immune cells that have become too zealous. Few chimeric antigens are completely specific for cancer, and other cells will be destroyed as well. The approach noted here is...
Source: Fight Aging! - January 17, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, January 3rd 2022
In this study, we showed that the iPaD (inducing Plagl2 and anti-Dyrk1a) lentivirus substantially rejuvenated the proliferative and neurogenic potential of NSCs in the aged brain. Clonal analysis by a sparse labeling approach as well as transcriptome analysis indicated that iPaD can rejuvenate aged NSCs (19-21 mo of age) to a level comparable with those at 1 or 2 months of age and successfully improved cognition of aged mice.
Once rejuvenated and activated by iPaD, aged dormant NSCs can generate, on average, 4.9 neurons but very few astrocytes in 3-week tracing. Furthermore, these activated NSCs were maintained for ...
Source: Fight Aging! - January 2, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Look Back at 2021: Progress Towards the Treatment of Aging as a Medical Condition
Well, here we are again, at the end of another pandemic year, a year older and - hopefully - a year wiser and more knowledgeable. I said all that really needs to be said on the topic of COVID-19 as an age-related condition at the end of last year. We might hope that, given widespread vaccination, the pandemic will become a topic of diminishing importance as the year ahead progresses, even given the present round of variants, fears, and reintroduction of restrictions.
Advocacy for Aging Research
Have we finally made significant progress in convincing the world that aging is the cause of age-related disease, th...
Source: Fight Aging! - December 31, 2021 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs
A Roundup of 2021 ’ s Quality Quotes
Happy almost New Year! Throughout 2021 we spoke to more than two dozen NIGMS-supported researchers for the Biomedical Beat blog. They shared their work, career journeys, experiences with the COVID-19 pandemic, and more. Here, we’re showcasing a few of their outstanding quotes. You can learn more about these scientists by checking out the links to the original blog posts.
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Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 29, 2021 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Source Type: blogs
Fight Aging! Newsletter, December 20th 2021
In conclusion, the low dose, prolonged angiotensin II exposure is associated with the induction of senescence in kidneys and the promotion of an inflammatory microenvironment through both secreted factors and immune cells. Endothelial cells appear to be a major cell type impacted. The elimination of senescent cells in the INK-ATTAC transgenic model prevents these effects of angiotensin II and reveals a novel pathophysiologic mechanism amenable to targeting by senolytic drugs in development.
CYTOR Upregulation as a Path to Improved Muscle Function in Later Life
https://www.fightaging.org/archives/2021/12/cytor-u...
Source: Fight Aging! - December 19, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, December 13th 2021
In conclusion, there is a good amount of pre-clinical and clinical data showing a strong positive correlation between reduction of senescent cells frequencies and functional improvement of skin. Whether senescence of skin cells makes a significant causal contribution to skin ageing can still not be conclusively decided, however. Nonetheless, there is strong evidence existing today to assume that better understanding of cell senescence in skin may lead to a breakthrough in interventions into skin ageing.
Isomerization of Tau May be Involved in Alzheimer's Disease
https://www.fightaging.org/archives/2021/12/isome...
Source: Fight Aging! - December 12, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Innovation, mRNA, and Public Policy
Chris EdwardsThe main weapons against COVID-19 are the vaccines developed by Moderna and BioNTech after a decade of their research into mRNA technologies. That research was supported by more than $3 billion of private angel investment and venture capital.Democrats and Republicans both support medical research funding, and Republicans tout the Trump administration ’s Operation Warp Speed. But governments were not the key to mRNA development. Instead, we can thank the leaders and scientists at Moderna and BioNTech and the suppliers of private capital to them, as I discusshere andhere.TheWall Street Journal ’s A...
Source: Cato-at-liberty - December 6, 2021 Category: American Health Authors: Chris Edwards Source Type: blogs
