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Hallucinations and illusions in migraine in children and the Alice in Wonderland Syndrome
Conclusions It is important to recognise these symptoms to enable appropriate history taking and diagnosis. These symptoms are common and currently seem to go unrecognised and may pose diagnostic difficulties if onset is before typical migraine headaches occur.
Source: Archives of Disease in Childhood - February 18, 2015 Category: Pediatrics Authors: Smith, R. A., Wright, B., Bennett, S. Tags: Headache (including migraine), Pain (neurology) Case report Source Type: research

TRPV1, CGRP and SP in scalp arteries of patients suffering from chronic migraine
Conclusions This study yields the first evidence for the existence of a TRPV1-LI innervation in human scalp arteries and provides the first quantitative assessment of the TRPV1-LI, CGRP-LI and SP-LI innervation of those vessels. The increase of TRPV1-LI periarterial nociceptive fibres of scalp arteries may represent, at least in some participants, a structural condition favouring CM (and possibly migraine), for example, by causing a higher sensitivity to algogenic agents.
Source: Journal of Neurology, Neurosurgery and Psychiatry - March 13, 2015 Category: Neurosurgery Authors: Del Fiacco, M., Quartu, M., Boi, M., Serra, M. P., Melis, T., Boccaletti, R., Shevel, E., Cianchetti, C. Tags: Immunology (including allergy), Drugs: CNS (not psychiatric), Headache (including migraine), Pain (neurology) Source Type: research

Migraine makes the stroke grow faster?
Long associated with increased incidence of stroke,1,2 migraine has been linked with mechanisms involving the vasculature (vasospasm, arterial dissection, endothelial dysfunction, venous thrombosis), heart (patent foramen ovale), and blood (hypercoagulability).3 Since cerebral ischemia can induce cortical spreading depression, the physiologic process underlying aura, migraine with aura may theoretically represent a TIA equivalent in a subset of people. In addition to the heightened occurrence of stroke in migraineurs, a growing body of evidence suggests more dire consequences when stroke occurs, with experiments in mice wi...
Source: Neurology - November 30, 2015 Category: Neurology Authors: Tietjen, G. E., Sacco, S. Tags: Migraine, All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Prevalence of lifetime depression in a large hemiplegic migraine cohort
Conclusions: Depression is part of the monogenic hemiplegic migraine phenotype. Further studies are needed to elucidate the pathophysiologic role of HM genes in comorbid depression. For now, clinicians should take comorbid depression into consideration when starting prophylactic treatment of HM.
Source: Neurology - November 27, 2016 Category: Neurology Authors: Louter, M. A., Pelzer, N., de Boer, I., Kuijvenhoven, B. E. C., van Oosterhout, W. P. J., van Zwet, E. W., Ferrari, M. D., Terwindt, G. M. Tags: Migraine, Depression, All epidemiology ARTICLE Source Type: research

Medical News Today: Retinal Migraine: Causes, Symptoms, and Treatment
Retinal migraine is an eye condition that affects some people who get migraine. Visual disturbances develop in one eye, followed by migraine symptoms.
Source: Health News from Medical News Today - December 31, 2016 Category: Consumer Health News Tags: Headache / Migraine Source Type: news

Depression in epilepsy, migraine, and multiple sclerosis: Epidemiology and how to screen for it
Purpose of review: To provide an overview of the epidemiology of depression in chronic neurologic conditions that can affect individuals throughout the lifespan (epilepsy, migraine, multiple sclerosis [MS]) and examine depression screening tools for adults with these conditions. Recent findings: Depression is common in neurologic conditions and can be associated with lower quality of life, higher health resource utilization, and poor adherence to treatment. It affects around 20%–30% of those with epilepsy, migraine, and MS, and evidence for a bidirectional association exists for each of these conditions. Depression ...
Source: Neurology Clinical Practice - April 10, 2017 Category: Neurology Authors: Jette, N., Amoozegar, F., Patten, S. B. Tags: Migraine, Depression, Multiple sclerosis, Screening in epidemiology, All Epilepsy/Seizures Review Source Type: research

Hypothalamus as a mediator of chronic migraine: Evidence from high-resolution fMRI
Conclusions: Our data corroborate the fact that the hypothalamus plays a crucial role in the pathophysiology of migraine chronification and acute pain stage of migraineurs. While the more posterior part of the hypothalamus seems to be important for the acute pain stage, the more anterior part seems to play an important role in attack generation and migraine chronification.
Source: Neurology - May 22, 2017 Category: Neurology Authors: Schulte, L. H., Allers, A., May, A. Tags: All Headache, Migraine, fMRI ARTICLE Source Type: research

Complementary and Integrative Health Treatments for Migraine
Conclusions: This article should provide an appreciation for the wide range of nonpharmacologic therapies that might be offered to patients in place of or in addition to migraine-preventive medications.
Source: Journal of Neuro-Ophthalmology - August 30, 2019 Category: Opthalmology Tags: Disease of the Year: Migraine Source Type: research

Two-year efficacy and safety of erenumab in participants with episodic migraine and 2-4 prior preventive treatment failures: results from the LIBERTY study
Conclusions Efficacy was sustained over 112 weeks in individuals with difficult-to-treat EM for whom 2–4 prior migraine preventives had failed. Erenumab treatment was safe and well tolerated, in-line with previous studies. Trial registration number NCT03096834
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 15, 2022 Category: Neurosurgery Authors: Ferrari, M. D., Reuter, U., Goadsby, P. J., Paiva da Silva Lima, G., Mondal, S., Wen, S., Tenenbaum, N., Pandhi, S., Lanteri-Minet, M., Stites, T. Tags: Open access Migraine Source Type: research

What Is the Difference Between Retinal Migraine and Ocular Migraine?
Title: What Is the Difference Between Retinal Migraine and Ocular Migraine?Category: Diseases and ConditionsCreated: 6/8/2022 12:00:00 AMLast Editorial Review: 6/8/2022 12:00:00 AM
Source: MedicineNet Migraine General - June 8, 2022 Category: Neurology Source Type: news

Characterization of Migraine in Children and Adolescents With Generalized Joint Hypermobility: A Case-Control Study
Discussion Youths with GJH and migraine were noted to have more severe migraine characteristics.
Source: Neurology Clinical Practice - August 17, 2023 Category: Neurology Authors: Ghosh, A., Horn, P. S., Kabbouche Samaha, M., Kacperski, J., LeCates, S. L., White, S., Powers, S. W., Hershey, A. D. Tags: Migraine, Pediatric headache, Adolescence Research Article Source Type: research

BET 2: Dexamethasone for reduction of migraine recurrence
Report by: Andrew Neill, Registrar Emergency Medicine Search checked by: Domhnall Brannigan, Consultant Emergency Medicine Institution: St Vincent's University Hospital, Dublin, Ireland Abstract A short-cut review was carried out to establish whether the administration of dexamethasone reduced the risk of recurrence of migraine headaches at 24 h. Three hundred and fifteen articles were found using the reported search including two systematic reviews and meta-analyses. A total of nine trials was included between the two meta-analyses. One trial was included in both analyses from the abstract data but had subsequently b...
Source: Emergency Medicine Journal - January 24, 2013 Category: Emergency Medicine Tags: EMJ Best evidence topic reports, Headache (including migraine), Pain (neurology), Pregnancy Source Type: research

Migraine Victims Suffer In Silence; Only Half Seek Diagnosis, Prescription Medication
Of those who suffer the debilitating side effects of migraine headaches, less than half get diagnosed. Most cope by isolating themselves, using over-the-counter medications, and suffering in silence. � But researchers at the University of Nebraska Medical Center College of Nursing Lincoln Division and Bryan Medical Center say many people could get more relief. The researchers -- Nancy Waltman, Ph.D., and Catherine Parker -- have been studying the effectiveness of an intervention to reduce the frequency, severity and disability from migraine headaches...
Source: Health News from Medical News Today - February 8, 2013 Category: Consumer Health News Tags: Headache / Migraine Source Type: news

Aspirin for acute migraine headaches in adults
Clinical bottom line A single oral dose of aspirin 900 mg or 1000 mg is more effective than placebo at resolving migrainous headache pain at 2 h and providing relief that is sustained over 24 h.1 Co-administration of metoclopramide 10 mg may provide additional pain relief and a greater reduction in associated symptoms, especially nausea.1 Background Migraine is a common, disabling, headache disorder, with considerable social and economic impact on the individual and society. Despite experiencing a high level of disability, most migraine sufferers do not seek professional advice, with many relying o...
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 8, 2013 Category: Neurosurgery Authors: Kirthi, V., Derry, S., Moore, R. A., McQuay, H. Tags: Headache (including migraine), Pain (neurology), Ophthalmology, Pain (palliative care), Pain (anaesthesia), Drugs: musculoskeletal and joint diseases Source Type: research

BET 1: Metoclopramide or prochlorperazine for headache in acute migraine?
A short-cut review was carried out to determine whether metoclopramide or prochlorperazine was better at relieving headache in patients attending the emergency department with acute migraine. Eighty-one papers were found using the reported searches, of which three presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of those best papers are shown in table 1. It is concluded that in adult patients presenting to the emergency department with acute migraine, prochlorperazine 10 mg is bet...
Source: Emergency Medicine Journal - June 13, 2013 Category: Emergency Medicine Tags: EMJ Best evidence topic reports, Headache (including migraine), Pain (neurology) Source Type: research