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Risky sexual practices and hepatitis C viremia among HIV-positive men who have sex with men in Taiwan
CONCLUSION: Among high-risk HIV-positive MSM, use of recreational drugs and risky sexual contacts were associated with HCV viremia, suggesting the mucosal contacts as the major route of HCV transmission.PMID:36702644 | DOI:10.1016/j.jmii.2023.01.006
Source: Journal of Microbiology, Immunology, and Infection - January 26, 2023 Category: Microbiology Authors: Miao-Hui Huang Guan-Jhou Chen Hsin-Yun Sun Yi-Ting Chen Li-Hsin Su Shu-Yuan Ho Sui-Yuan Chang Sung-Hsi Huang Yi-Chia Huang Wang-Da Liu Kuan-Yin Lin Yu-Shan Huang Yi-Ching Su Wen-Chun Liu Chien-Ching Hung Source Type: research

Age biases in a large HIV and sexual behaviour-related internet survey among MSM
Conclusion: Internet samples are biased towards a lower median age because younger men are over-represented on MSM dating websites and therefore may be more likely to be recruited into surveys. Men diagnosed with HIV were over-represented in the internet survey, and increasingly so in the older age groups. A similar effect was observed in the age groups younger than 25 years. Self-reported peak prevalence and peak HIV diagnoses rates are often shifted to higher age groups in internet samples compared to surveillance data. Adjustment for age-effects on online accessibility should be considered when linking data from interne...
Source: BMC Public Health - Latest articles - September 10, 2013 Category: Consumer Health News Authors: Ulrich MarcusFord HicksonPeter WeatherburnAxel Schmidt Source Type: research

Increasing condom use and declining STI prevalence in high-risk MSM and TGs: evaluation of a large-scale prevention program in Tamil Nadu, India
Background: This paper presents an evaluation of Avahan, a large scale HIV prevention program that was implemented using peer-mediated strategies, condom distribution and sexually transmitted infection (STI) clinical services among high-risk men who have sex with men (HR-MSM) and male to female transgender persons (TGs) in six high-prevalence state of Tamil Nadu, in southern India. Methods: Two rounds of large scale cross-sectional bio-behavioural surveys among HR-MSM and TGs and routine program monitoring data were used to assess changes in program coverage, condom use and prevalence of STIs (including HIV) and their asso...
Source: BMC Public Health - Latest articles - September 17, 2013 Category: Consumer Health News Authors: Thilakavathi SubramanianLakshmi RamakrishnanSanthakumar AridossPrabuddhagopal GoswamiBoopathi KanguswamiMathew ShajanRajat AdhikaryGirish PurushothamanSenthil RamamoorthyEswaramurthy ChinnaswamyIlaya VeeramaniRamesh Paranjape Source Type: research

High HIV seroprevalence, rectal STIs and risky sexual behaviour in men who have sex with men in Dar es Salaam and Tanga, Tanzania
Conclusions HIV and STI rates were substantially lower in MSM in a provincial city than in a large metropolis and rates appear to depend on larger numbers of MSM known. Most HIV detected were new cases, and there was a high burden of asymptomatic curable rectal STIs (>1 in 5 MSM). Owing to stigma, MSM may not report homosexuality and thus not have rectal STIs treated. High need for tailored HIV testing and STI screening and treatment of MSM in Tanzania is apparent.
Source: BMJ Open - August 28, 2014 Category: Journals (General) Authors: Ross, M. W., Nyoni, J., Ahaneku, H. O., Mbwambo, J., McClelland, R. S., McCurdy, S. A. Tags: Open access, Infectious diseases, HIV AIDS Research Source Type: research

Methylsulfonylmethane inhibits NLRP3 inflammasome activation.
In this study, we tested the effect of MSM on inflammasome activation using mouse and human macrophages. In our results, MSM significantly attenuated NLRP3 inflammasome activation in lipopolysaccharide-primed macrophages, although it had no effect on NLCR4 or AIM2 inflammasome activation. Extracts of MSM-enriched vegetables presented the same inhibitory effect on NLRP3 inflammasome activation as MSM. MSM also attenuated the transcriptional expression of IL-1α, IL-1β, IL-6, and NLRP3. Taken together, these results show that MSM has anti-inflammatory characteristics, interrupts NLRP3 inflammasome activation, and inhibits p...
Source: Cytokine - November 21, 2014 Category: Molecular Biology Authors: Ahn H, Kim J, Lee MJ, Kim YJ, Cho YW, Lee GS Tags: Cytokine Source Type: research

Pleasure, Affection, and Love Among Black Men Who Have Sex with Men (MSM) versus MSM of Other Races: Countering Dehumanizing Stereotypes via Cross-Race Comparisons of Reported Sexual Experience at Last Sexual Event.
This study sought to describe pleasure, affection, and love experienced by Black men who have sex with men (MSM) during their last male-partnered sexual event and to examine differences relative to White, Latino, and Asian MSM. A total of 21,696 (793 Black, 18,905 White, 1,451 Latino, and 547 Asian) U.S. men ages 18-87 (M Age = 39) were recruited from social/sexual networking sites targeting MSM in 2010-2011. Participants reported multiple dimensions of sexual experience (pleasure, affection, and love) occurring at their last male-partnered sexual event, partner relationship, and sociodemographic characteristics. Across ...
Source: Archives of Sexual Behavior - January 21, 2015 Category: Psychiatry & Psychology Authors: Calabrese SK, Rosenberger JG, Schick VR, Novak DS Tags: Arch Sex Behav Source Type: research

MSM ameliorates HIV-1 Tat induced neuronal oxidative stress via rebalance of the glutathione cycle.
This study was conducted to determine whether administration of MSM attenuates HIV-1 Tat induced oxidative stress in mouse neuronal cells. MSM treatment significantly decreased neuronal cell NO and ROS secretion. Further, MSM significantly reversed HIV-1 Tat mediated reductions in reduced glutathione (GSH) as well as HIV-1 Tat mediated increases in oxidized glutathione (GSSG). In addition, Tat reduced nuclear translocation of nuclear factor-erythroid 2 p45-related factor 2 (Nrf2), a key nuclear promoter of antioxidant activity, while MSM increased its translocation to the nucleus in the presence of Tat. These results sugge...
Source: American Journal of Translational Research - April 24, 2015 Category: Research Tags: Am J Transl Res Source Type: research

Correlates of anal sex roles among Malay and Chinese MSM in Kuala Lumpur, Malaysia
We describe the prevalence of identifying as being ‘top’, ‘bottom’, ‘versatile’, or ‘don’t know/not applicable’ among Malay and Chinese MSM in Kuala Lumpur, Malaysia, and behavioural outcomes according to these labels for sexual role identity. Data analysis was conducted on a survey administered during weekly outreach throughout Kuala Lumpur in 2012. Pearson’s Chi square tests were used to compare demographic and behavioural characteristics of MSM who reported roles for anal sex. Binary logistic regression was used to explore the odds of behavioural outcomes among...
Source: International Journal of STD and AIDS - February 11, 2016 Category: Global & Universal Authors: Dangerfield, D. T., Gravitt, P., Rompalo, A. M., Tai, R., Lim, S. H. Tags: Original research articles Source Type: research

Genetic diversity and transmission networks of HIV-1 strains among men having sex with men (MSM) in Lomé, Togo.
Abstract Understanding the HIV epidemic in key populations is important. Today only scarce information is available on HIV-1 strains that circulate in men having sex with men (MSM) in sub-Saharan Africa. Here, we studied for the first time the genetic diversity of HIV-1 strains circulating in the MSM population in Lomé, the capital city from Togo. The overall subtype/CRF distribution in pol (protease and/or partial reverse transcriptase (RT)) among the 79 HIV-1 strains from MSM was as follows: CRF02_AG (72%, n=57), subtype G (2.5%, n=2), sub-subtype A3 (1.3%, n=1), and unique recombinant forms (URF) (24%, n=19). ...
Source: Infection, Genetics and Evolution - May 24, 2016 Category: Genetics & Stem Cells Authors: Konou AA, Vidal N, Salou M, Anato S, Singo-Tokofaï A, Ekouevi DK, Pitché P, Prince-David M, Delaporte E, Peeters M, Dagnra AY Tags: Infect Genet Evol Source Type: research

HIV Testing Among Internet-Using MSM in the United States: Systematic Review
AbstractRegular HIV testing enables early identification and treatment of HIV among at-risk men who have sex with men (MSM). Characterizing HIV testing needs for Internet-using MSM informs development of Internet-facilitated testing interventions. In this systematic review we analyze HIV testing patterns among Internet-using MSM in the United States who report, through participation in an online study or survey, their HIV status as negative or unknown and identify demographic or behavioral risk factors associated with testing. We systematically searched multiple electronic databases for relevant English-language articles p...
Source: AIDS and Behavior - August 5, 2016 Category: Infectious Diseases Source Type: research

Bayesian Approaches to Racial Disparities in HIV Risk Estimation Among Men Who Have Sex with Men
Conclusions: The observed race-specific associations in MSM are likely not due to misclassification alone, but represent a constellation of factors that differ between racial groups. We recommend specific risk factors in surveys needed to further identify the behavioral characteristics that lead to the observed differences when the estimates are stratified by race.
Source: Epidemiology - February 1, 2017 Category: Epidemiology Tags: Infectious diseases Source Type: research

Behavioural, not biological, factors drive the HCV epidemic among HIV-positive MSM: HCV and HIV modelling analysis including HCV treatment-as-prevention impact
ConclusionsSexual behaviour patterns likely drive observed HCV infection patterns among HIV-positive MSM. Changes in these patterns could disseminate HCV amongst HIV-negative MSM, limiting the impact of targeting HCV treatment to HIV-diagnosed MSM.
Source: International Journal of Epidemiology - June 12, 2017 Category: Epidemiology Source Type: research

Uptake of HIV self-testing and linkage to treatment among men who have sex with men (MSM) in Nigeria: A pilot programme using key opinion leaders to reach MSM.
CONCLUSIONS: HIVST distribution through KOLs was feasible and oral self-testing was highly acceptable among this urban MSM population. Despite concerns about linkage to treatment when implementing self-testing, this study showed that linkage to treatment can be achieved with active follow-up and access to a trusted MSM-friendly community clinic that offers HIV treatment. HIVST should be considered as an additional option to standard HIV testing models for MSM. PMID: 30033680 [PubMed - in process]
Source: Journal of the International AIDS Society - July 25, 2018 Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research

Men Who Have Sex with Men (MSM) Who Have Not Previously Tested for HIV: Results from the MSM Testing Initiative, United States (2012 –2015)
AbstractThe Centers for Disease Control and Prevention recommends annual HIV tests for men who have sex with men (MSM), yet some have never tested. We analyzed data from the MSM Testing Initiative. Of 68,185 HIV tests, 8% were with MSM who never previously tested ( “first-time testers”). Among tests with first-time testers, 70.7% were with MSM from racial or ethnic minorities; 66.5% were with MSM younger than 30 years. Tests with MSM who reported female partners only during the past year (compared to male partners only) or were recruited for at-home testi ng (compared to venue-based recruitment) were 4 times (prevalen...
Source: AIDS and Behavior - September 1, 2018 Category: Infectious Diseases Source Type: research

Factors associated with concurrent sexual partnerships among men who have sex with men in Yangon, Myanmar.
This study aimed to identify factors associated with CSP among MSM.A cross-sectional study was conducted from September to October 2011 in Yangon, Myanmar. In total, 353 males who had self-reported sex with men were recruited using respondent-driven sampling method. Descriptive statistics and multivariate logistic regression analysis were performed. In total, 61.0% of the MSM reported having CSP. MSM who practiced sex trading in the past six months (adjusted odds ratio8.32; 95% confidence interval [CI]: 2.30-30.10), MSM who had diagnosed with STIs/HIV (AOR 6.71; 95% CI: 4.78-9.28), and MSM who engaged in unprotected insert...
Source: Nagoya Journal of Medical Science - December 29, 2018 Category: International Medicine & Public Health Tags: Nagoya J Med Sci Source Type: research

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