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Transcription factor-based biosensors for detection of naturally occurring phenolic acids
N Biotechnol. 2023 Sep 13:S1871-6784(23)00047-X. doi: 10.1016/j.nbt.2023.09.004. Online ahead of print.ABSTRACTPhenolic acids including hydroxybenzoic and hydroxycinnamic acids are secondary plant and fungal metabolites involved in many physiological processes offering health and dietary benefits. They are often utilised as precursors for production of value-added compounds. The limited availability of synthetic biology tools, such as whole-cell biosensors suitable for monitoring the dynamics of phenolic acids intracellularly and extracellularly, hinders the capabilities to develop high-throughput screens to study their me...
Source: New Biotechnology - September 15, 2023 Category: Biotechnology Authors: Ernesta Augustiniene Ingrida Kutraite Egle Valanciene Paulius Matulis Ilona Jonuskiene Naglis Malys Source Type: research

A Campylobacteriosis Outbreak Caused by One Asymptomatic Food Handler Carrier
Biomed Environ Sci. 2023 Aug 20;36(8):779-782. doi: 10.3967/bes2023.105.ABSTRACTIn August 2021, three students with diarrhea from the same school visited a local hospital in the S district of Beijing. An epidemic investigation showed that there were more students with diarrhea in the same school and they had one meal together. Campylobacter jejuni was isolated from both patients with diarrhea and asymptomatic food handlers; however, the latter also carried Campylobacter coli. Phylogenomic analysis showed that there was a campylobacteriosis outbreak among the students, and the asymptomatic food handler may have been the sou...
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Ai Xia Yan Gui Lan Zhou Peng Gao Ying Kang Shou Fei Li Yuan Yuan Wang Feng Shuang Wang Hai Rui Wang Ying Li Mao Jun Zhang Source Type: research

Causative Microorganisms Isolated from Patients with Intra-Abdominal Infections and Their Drug Resistance Profiles: An 11-Year (2011-2021) Single-Center Retrospective Study
CONCLUSION: The distribution and antimicrobial susceptibility of the causative microorganisms from patients with IAIs were altered between 2011 and 2021. This finding is valuable for the implementation of evidence-based antimicrobial therapy and provides guidance for the control of hospital infections.PMID:37711085 | DOI:10.3967/bes2023.072
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Rui Ding Rui Rui Ma Ya Li Liu Ying Zhao Li Na Guo Hong Tao Dou Hong Li Sun Wen Jing Liu Li Zhang Yao Wang Ding Ding Li Qiao Lian Yi Ying Chun Xu Source Type: research

A Campylobacteriosis Outbreak Caused by One Asymptomatic Food Handler Carrier
Biomed Environ Sci. 2023 Aug 20;36(8):779-782. doi: 10.3967/bes2023.105.ABSTRACTIn August 2021, three students with diarrhea from the same school visited a local hospital in the S district of Beijing. An epidemic investigation showed that there were more students with diarrhea in the same school and they had one meal together. Campylobacter jejuni was isolated from both patients with diarrhea and asymptomatic food handlers; however, the latter also carried Campylobacter coli. Phylogenomic analysis showed that there was a campylobacteriosis outbreak among the students, and the asymptomatic food handler may have been the sou...
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Ai Xia Yan Gui Lan Zhou Peng Gao Ying Kang Shou Fei Li Yuan Yuan Wang Feng Shuang Wang Hai Rui Wang Ying Li Mao Jun Zhang Source Type: research

Causative Microorganisms Isolated from Patients with Intra-Abdominal Infections and Their Drug Resistance Profiles: An 11-Year (2011-2021) Single-Center Retrospective Study
CONCLUSION: The distribution and antimicrobial susceptibility of the causative microorganisms from patients with IAIs were altered between 2011 and 2021. This finding is valuable for the implementation of evidence-based antimicrobial therapy and provides guidance for the control of hospital infections.PMID:37711085 | DOI:10.3967/bes2023.072
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Rui Ding Rui Rui Ma Ya Li Liu Ying Zhao Li Na Guo Hong Tao Dou Hong Li Sun Wen Jing Liu Li Zhang Yao Wang Ding Ding Li Qiao Lian Yi Ying Chun Xu Source Type: research

Transcription factor-based biosensors for detection of naturally occurring phenolic acids
N Biotechnol. 2023 Sep 13:S1871-6784(23)00047-X. doi: 10.1016/j.nbt.2023.09.004. Online ahead of print.ABSTRACTPhenolic acids including hydroxybenzoic and hydroxycinnamic acids are secondary plant and fungal metabolites involved in many physiological processes offering health and dietary benefits. They are often utilised as precursors for production of value-added compounds. The limited availability of synthetic biology tools, such as whole-cell biosensors suitable for monitoring the dynamics of phenolic acids intracellularly and extracellularly, hinders the capabilities to develop high-throughput screens to study their me...
Source: New Biotechnology - September 15, 2023 Category: Biotechnology Authors: Ernesta Augustiniene Ingrida Kutraite Egle Valanciene Paulius Matulis Ilona Jonuskiene Naglis Malys Source Type: research

A Campylobacteriosis Outbreak Caused by One Asymptomatic Food Handler Carrier
Biomed Environ Sci. 2023 Aug 20;36(8):779-782. doi: 10.3967/bes2023.105.ABSTRACTIn August 2021, three students with diarrhea from the same school visited a local hospital in the S district of Beijing. An epidemic investigation showed that there were more students with diarrhea in the same school and they had one meal together. Campylobacter jejuni was isolated from both patients with diarrhea and asymptomatic food handlers; however, the latter also carried Campylobacter coli. Phylogenomic analysis showed that there was a campylobacteriosis outbreak among the students, and the asymptomatic food handler may have been the sou...
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Ai Xia Yan Gui Lan Zhou Peng Gao Ying Kang Shou Fei Li Yuan Yuan Wang Feng Shuang Wang Hai Rui Wang Ying Li Mao Jun Zhang Source Type: research

Causative Microorganisms Isolated from Patients with Intra-Abdominal Infections and Their Drug Resistance Profiles: An 11-Year (2011-2021) Single-Center Retrospective Study
CONCLUSION: The distribution and antimicrobial susceptibility of the causative microorganisms from patients with IAIs were altered between 2011 and 2021. This finding is valuable for the implementation of evidence-based antimicrobial therapy and provides guidance for the control of hospital infections.PMID:37711085 | DOI:10.3967/bes2023.072
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Rui Ding Rui Rui Ma Ya Li Liu Ying Zhao Li Na Guo Hong Tao Dou Hong Li Sun Wen Jing Liu Li Zhang Yao Wang Ding Ding Li Qiao Lian Yi Ying Chun Xu Source Type: research

A Campylobacteriosis Outbreak Caused by One Asymptomatic Food Handler Carrier
Biomed Environ Sci. 2023 Aug 20;36(8):779-782. doi: 10.3967/bes2023.105.ABSTRACTIn August 2021, three students with diarrhea from the same school visited a local hospital in the S district of Beijing. An epidemic investigation showed that there were more students with diarrhea in the same school and they had one meal together. Campylobacter jejuni was isolated from both patients with diarrhea and asymptomatic food handlers; however, the latter also carried Campylobacter coli. Phylogenomic analysis showed that there was a campylobacteriosis outbreak among the students, and the asymptomatic food handler may have been the sou...
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Ai Xia Yan Gui Lan Zhou Peng Gao Ying Kang Shou Fei Li Yuan Yuan Wang Feng Shuang Wang Hai Rui Wang Ying Li Mao Jun Zhang Source Type: research

Causative Microorganisms Isolated from Patients with Intra-Abdominal Infections and Their Drug Resistance Profiles: An 11-Year (2011-2021) Single-Center Retrospective Study
CONCLUSION: The distribution and antimicrobial susceptibility of the causative microorganisms from patients with IAIs were altered between 2011 and 2021. This finding is valuable for the implementation of evidence-based antimicrobial therapy and provides guidance for the control of hospital infections.PMID:37711085 | DOI:10.3967/bes2023.072
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Rui Ding Rui Rui Ma Ya Li Liu Ying Zhao Li Na Guo Hong Tao Dou Hong Li Sun Wen Jing Liu Li Zhang Yao Wang Ding Ding Li Qiao Lian Yi Ying Chun Xu Source Type: research

Alterations of fecal microbiome and metabolome in pemphigus patients
J Autoimmun. 2023 Sep 13:103108. doi: 10.1016/j.jaut.2023.103108. Online ahead of print.ABSTRACTThe role of gut microbiome and metabolic substances in the development of autoimmune diseases has gradually been revealed. However, the relevant gut features in pemphigus have not been well clarified. We collected stool samples from pemphigus patients and healthy controls (HCs). Metagenomic sequencing and liquid chromatography-mass spectrometry (LC/MS) metabolome sequencing were performed to analyze the compositional and metabolic alternations of the gut microbiome in pemphigus patients and HCs. We observed the reduced richness ...
Source: Journal of Autoimmunity - September 15, 2023 Category: Allergy & Immunology Authors: Ziyu Guo Nam Yiu Zhi Hu Wenyu Zhou Xuan Long Miao Yang Jieyue Liao Guiying Zhang Qianjin Lu Ming Zhao Source Type: research

Anticancer Effects of Cell-Free Culture Supernatant of Escherichia coli in Bladder Cancer Cell Line: New Insight into the Regulation of Inflammation
In conclusion, our findings demonstrate that this compound is a potential candidate for the suppression of bladder cancer progression.PMID:37708921 | DOI:10.1016/j.gene.2023.147795
Source: Gene - September 14, 2023 Category: Genetics & Stem Cells Authors: Amirreza Mehmandar-Oskuie Masoud Tohidfar Bahareh Hajikhani Forouzan Karimi Source Type: research