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Infectious Disease: Coronavirus

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Total 74749 results found since Jan 2013.

The impact of the COVID-19 pandemic on erectile function in Chinese CP/CPPS patients
This study aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on erectile function in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). A retrospective study was conducted on 657 CP/CPPS patients who visited The Third Xiangya Hospital of Central South University (Changsha, China) from November 2018 to November 2022. Patients were divided into two groups based on the timeline before and after the COVID-19 outbreak in China. The severity of CP/CPPS, penile erection status, anxiety, and depression was evaluated using the National Institutes of Health-Chronic Pro...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Wei-Jie Song Ji-Wei Huang Yuan Liu Wei Ding Zhi Long Le-Ye He Source Type: research

The Changing Landscape of Global Child Health Education in the United States and the Effects of the COVID-19 Pandemic and Civil Unrest
Pediatr Ann. 2023 Sep;52(9):e324-e329. doi: 10.3928/19382359-20230720-02. Epub 2023 Sep 1.ABSTRACTThe events of recent years have affected the landscape of global child health education (GCHE) in the United States. War, racism, forced displacement, and the coronavirus disease 2019 (COVID-19) pandemic had global repercussions that reached US GCHE. The aim of this article is to examine the effect of these events on the landscape of GCHE in the US. Key areas of GCHE have been reframed, reshaped, and accelerated by these events. Travel restrictions accelerated virtual learning opportunities. Core curriculum needed to be recons...
Source: Pediatric Annals - September 11, 2023 Category: Pediatrics Authors: Ashley Bjorklund Mounika Muttineni Sophia Gladding Tina Slusher Cynthia R Howard Source Type: research

Analytical tool for COVID-19 using an SIR model equivalent to the chain reaction equation of infection
Biosystems. 2023 Sep 8:105029. doi: 10.1016/j.biosystems.2023.105029. Online ahead of print.ABSTRACTInsights from data analysis of existing cases are important to prevent future outbreaks of coronavirus disease 2019 (COVID-19). Although mathematical models are expected to be useful for this purpose, the adequacy of reproducibility of these models is difficult to confirm because they are based on hypotheses. For example, using the time variation of the parameter of the basic reproduction number for the time variation of complex data on the number of infected persons is a change of expression and does not capture the substan...
Source: Biosystems - September 10, 2023 Category: Biotechnology Authors: Koichiro Maki Source Type: research

Natural PAK1 inhibitors: potent anti-inflammatory effectors for prevention of pulmonary fibrosis in COVID-19 therapy
Nat Prod Res. 2023 Sep 10:1-13. doi: 10.1080/14786419.2023.2254454. Online ahead of print.ABSTRACTOne of the main efforts of scientists to study drug development is the discovery of novel antiviral agents that could be beneficial in the struggle against viruses that cause diseases in humans. Natural products are complex metabolites that are designed and synthesised by different sources in an attempt to optimise nature. Recently, natural products are still a source of biologically active molecules, facilitating drug discovery. A p21-activating kinase PAK1 is a key regulator of cytoskeletal actin assembly, phenotypic signall...
Source: Natural Product Research - September 10, 2023 Category: Biochemistry Authors: Idris Arslan Source Type: research

The old and the new: The EG.5 ('Eris') sub-variant of Coronavirus
Eur J Intern Med. 2023 Sep 8:S0953-6205(23)00323-0. doi: 10.1016/j.ejim.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37690919 | DOI:10.1016/j.ejim.2023.09.003
Source: European Journal of Internal Medicine - September 10, 2023 Category: Internal Medicine Authors: Martina Zappa Paolo Verdecchia Andrea Andolina Fabio Angeli Source Type: research

HLA alleles: important pieces to the COVID-19 puzzle
Trends Immunol. 2023 Sep 9:S1471-4906(23)00179-5. doi: 10.1016/j.it.2023.08.011. Online ahead of print.ABSTRACTResearch on human leukocyte antigen (HLA) molecules in coronavirus disease 2019 (COVID-19) raised high expectations but has yielded limited results. Augusto et al.'s recent study in Nature unveils a strong association of HLA-B*15:01 with asymptomatic COVID-19, representing an important contribution to genetics in COVID-19.PMID:37690961 | DOI:10.1016/j.it.2023.08.011
Source: Trends in Immunology - September 10, 2023 Category: Allergy & Immunology Authors: Patricia Castro-Santos Ángel Carracedo Roberto D íaz-Peña Source Type: research

The old and the new: The EG.5 ('Eris') sub-variant of Coronavirus
Eur J Intern Med. 2023 Sep 8:S0953-6205(23)00323-0. doi: 10.1016/j.ejim.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37690919 | DOI:10.1016/j.ejim.2023.09.003
Source: European Journal of Internal Medicine - September 10, 2023 Category: Internal Medicine Authors: Martina Zappa Paolo Verdecchia Andrea Andolina Fabio Angeli Source Type: research

Analytical tool for COVID-19 using an SIR model equivalent to the chain reaction equation of infection
Biosystems. 2023 Sep 8:105029. doi: 10.1016/j.biosystems.2023.105029. Online ahead of print.ABSTRACTInsights from data analysis of existing cases are important to prevent future outbreaks of coronavirus disease 2019 (COVID-19). Although mathematical models are expected to be useful for this purpose, the adequacy of reproducibility of these models is difficult to confirm because they are based on hypotheses. For example, using the time variation of the parameter of the basic reproduction number for the time variation of complex data on the number of infected persons is a change of expression and does not capture the substan...
Source: Biosystems - September 10, 2023 Category: Biotechnology Authors: Koichiro Maki Source Type: research

The old and the new: The EG.5 ('Eris') sub-variant of Coronavirus
Eur J Intern Med. 2023 Sep 8:S0953-6205(23)00323-0. doi: 10.1016/j.ejim.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37690919 | DOI:10.1016/j.ejim.2023.09.003
Source: European Journal of Internal Medicine - September 10, 2023 Category: Internal Medicine Authors: Martina Zappa Paolo Verdecchia Andrea Andolina Fabio Angeli Source Type: research

HLA alleles: important pieces to the COVID-19 puzzle
Trends Immunol. 2023 Sep 9:S1471-4906(23)00179-5. doi: 10.1016/j.it.2023.08.011. Online ahead of print.ABSTRACTResearch on human leukocyte antigen (HLA) molecules in coronavirus disease 2019 (COVID-19) raised high expectations but has yielded limited results. Augusto et al.'s recent study in Nature unveils a strong association of HLA-B*15:01 with asymptomatic COVID-19, representing an important contribution to genetics in COVID-19.PMID:37690961 | DOI:10.1016/j.it.2023.08.011
Source: Trends in Immunology - September 10, 2023 Category: Allergy & Immunology Authors: Patricia Castro-Santos Ángel Carracedo Roberto D íaz-Peña Source Type: research

Natural PAK1 inhibitors: potent anti-inflammatory effectors for prevention of pulmonary fibrosis in COVID-19 therapy
Nat Prod Res. 2023 Sep 10:1-13. doi: 10.1080/14786419.2023.2254454. Online ahead of print.ABSTRACTOne of the main efforts of scientists to study drug development is the discovery of novel antiviral agents that could be beneficial in the struggle against viruses that cause diseases in humans. Natural products are complex metabolites that are designed and synthesised by different sources in an attempt to optimise nature. Recently, natural products are still a source of biologically active molecules, facilitating drug discovery. A p21-activating kinase PAK1 is a key regulator of cytoskeletal actin assembly, phenotypic signall...
Source: Natural Product Research - September 10, 2023 Category: Biochemistry Authors: Idris Arslan Source Type: research

HLA alleles: important pieces to the COVID-19 puzzle
Trends Immunol. 2023 Sep 9:S1471-4906(23)00179-5. doi: 10.1016/j.it.2023.08.011. Online ahead of print.ABSTRACTResearch on human leukocyte antigen (HLA) molecules in coronavirus disease 2019 (COVID-19) raised high expectations but has yielded limited results. Augusto et al.'s recent study in Nature unveils a strong association of HLA-B*15:01 with asymptomatic COVID-19, representing an important contribution to genetics in COVID-19.PMID:37690961 | DOI:10.1016/j.it.2023.08.011
Source: Trends in Immunology - September 10, 2023 Category: Allergy & Immunology Authors: Patricia Castro-Santos Ángel Carracedo Roberto D íaz-Peña Source Type: research

New variant of COVID-19
A new variant is not a new thing, of course, but BA.2.86, known also as Pirola, seems to be causing some concern in the UK and elsewhere.  It seems a long time ago that I compiled page after page on this blog about COVID-19.  Those pages are still there, hopefully all labelled to make it clear they are no longer being updated.I wondered if a few resources on this new variant would be useful.  In case I am right, here are some.  I don ' t know how long this one will be useful for, but will try to keep it updated.  A PubMed search for BA.2.86 finds a few.  Adding Pi...
Source: Browsing - September 9, 2023 Category: Databases & Libraries Tags: coronavirus COVID-19 Source Type: blogs

Broad-Spectrum Antiviral Effect of Cannabidiol Against Enveloped and Nonenveloped Viruses
Conclusions: It was demonstrated that CBD inhibits structurally dissimilar viruses, suggesting that this phytochemical has broad-spectrum antiviral effect, representing a valuable alternative in emergency situations during viral outbreaks, like the one caused by severe acute respiratory syndrome coronavirus 2 in 2020.PMID:37682578 | DOI:10.1089/can.2023.0103
Source: Cell Research - September 8, 2023 Category: Cytology Authors: Agostina B Marquez Josefina Vicente Eliana Castro Daiana Vota Mar ía S Rodríguez-Varela Priscila A Lanza Castronuovo Giselle M Fuentes Alejandro R Parise Leonardo Romorini Diego E Alvarez Carlos A Bueno Cristina L Ramirez Agustina Alaimo Cybele C Garc Source Type: research