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Enhancing Healthcare Through Industry-Specific Large Language Models
The following is a guest article by Tisson Mathew, Founder and CEO at SkyPoint AI
Why Large Language Models Trained on Industry Context are Essential for Effective Generative AI in the Healthcare Space
Ask ChatGPT an important but complicated healthcare-related question, and you might very well get a wrong—and potentially dangerous—answer. Navigating the complexities of medical data, regulations, and patient care can place demands on generative AI technologies that can’t be fulfilled. But there is a way to take full advantage of the power of GenAI — with industry-specific LLMs that are securely supplied wit...
Source: EMR and HIPAA - September 13, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System AI Companion DataStax EMR Generative AI Healthcare AI Healthcare AI Ethics Healthcare ChatGPT Healthcare LLMs Large Language Models Source Type: blogs
Linkage of blood cell division cycle 42 with T helper cells, and their correlation with anxiety, depression, and cognitive impairment in stroke patients
This study aimed to assess the correlation between blood CDC42 and Th cells, and their association with mental issues in stroke patients. Peripheral blood samples were obtained from 264 stroke patients and 50 controls. Then, serum CDC42 was measured by enzyme-linked immunosorbent assay, and Th1, Th2, and Th17 cells were detected by flow cytometry. Hospital Anxiety and Depression Scale (HADS) and Mini Mental State Examination (MMSE) were applied to patients. CDC42 was decreased (P<0.001), Th1 (P=0.013) and Th17 (P<0.001) cells were elevated, while Th2 cells (P=0.108) showed no difference in stroke patients compared to...
Source: Braz J Med Biol Res - September 13, 2023 Category: Research Authors: Haifeng Ma Qing Chang Jujuan Jia Yaoyuan Zhang Gang Wang Yuanyuan Li Source Type: research
An Estimation Formula for Resonance Frequency Using Sex and Height for Healthy Individuals and Patients with Incurable Cancers
Appl Psychophysiol Biofeedback. 2023 Sep 13. doi: 10.1007/s10484-023-09602-5. Online ahead of print.ABSTRACTResonance frequency breathing is a technique that involves breathing that maximizes heart rate variability. It is specific to individuals and is determined through a procedure taking approximately 30 min, using a procedure that is often best carried out at specialized medical institutions. This is a physical and time-consuming burden because of hospital visits and measurements, particularly for patients with cancer. Therefore it would be beneficial if a procedure can be found to determine resonance frequency from the...
Source: Applied Psychophysiology and Biofeedback - September 13, 2023 Category: Psychiatry & Psychology Authors: Hideaki Hasuo Keita Mori Hiromichi Matsuoka Hiroko Sakuma Hideki Ishikawa Source Type: research
HIV/STD prevalence and test uptake among african in Guangzhou, China: an analysis of data from hospital-based surveillance
BMC Infect Dis. 2023 Sep 13;23(1):597. doi: 10.1186/s12879-023-08590-5.ABSTRACTHuman immunodeficiency virus (HIV) and sexually transmitted diseases (STDs) cause substantial morbidity and mortality both in African and China. However, there is limited data available on the prevalence of HIV/STDs and the uptake of testing experience ever during in China among African migrants. A venue-based survey was conducted at a tertiary hospital in Guangzhou to investigate the prevalence of HIV/STDs through laboratory testing and identify the associated factors. A total of 200 eligible participants completed the survey and bring into the...
Source: Herpes - September 13, 2023 Category: Infectious Diseases Authors: Mingzhou Xiong Menglan Yang Peizhen Zhao Shujie Huang Cheng Wang Source Type: research
Problem exploration for creating value propositions when developing point-of-care solutions
Biosens Bioelectron. 2023 Aug 31;241:115636. doi: 10.1016/j.bios.2023.115636. Online ahead of print.ABSTRACTPoint-of-care (POC) testing has been increasingly proposed as one of the most promising solutions for improving healthcare provision as it enables fast and accurate testing both inside and outside hospital settings. Many of these POC device stem from academic research. Yet, the commercialization of these devices through academic spin-offs is not straigthforward. Many academic spin-offs fail due to an inproperly articulated value proposition. To create a value proposition with biosensors it is crucial to understand ho...
Source: Biosensors and Bioelectronics - September 13, 2023 Category: Biotechnology Authors: Annelies Bobelyn Rene Unteregger Johanna I H öffken Isabelle Reymen Source Type: research
Outcomes of Children Discharged Prior to Absolute Neutrophil Count Recovery After Admission for Febrile Neutropenia
J Pediatr Hematol Oncol. 2023 Sep 13. doi: 10.1097/MPH.0000000000002757. Online ahead of print.ABSTRACTFebrile neutropenia (FN) management in pediatric oncology patients traditionally necessitates inpatient admission until evidence of bone marrow recovery. Discharge before count recovery may be a way to safely reduce the length of hospitalizations for select patients. A chart review was conducted of patients admitted for FN at one tertiary care children's hospital, where the standard is to discharge well-appearing patients after 48 hours of negative cultures if afebrile for at least 24 hours, irrespective of absolute neutr...
Source: Ann Oncol - September 13, 2023 Category: Cancer & Oncology Authors: Sarah Peters Mark Adler Jenna Rossoff Source Type: research
Infections due to Salmonella sp. in children with chronic granulomatous disease: Our experience from North India
Clin Immunol. 2023 Sep 11:109769. doi: 10.1016/j.clim.2023.109769. Online ahead of print.ABSTRACTInfections with non-typhoidal Salmonella sp. have been documented in children with chronic granulomatous disease (CGD), but the prevalence of salmonella infection in children with CGD in underdeveloped countries is unknown. We assessed the clinical profiles of CGD patients diagnosed at our tertiary care centre in north India and had Salmonella sp.infections. We found three patients with Salmonella sp. bloodstream infections (2-proven, 1-probable) among the 99 CGD patients. After receiving cotrimoxazole prophylaxis following a C...
Source: Clinical Immunology - September 13, 2023 Category: Allergy & Immunology Authors: Suprit Basu Pandiarajan Vignesh K Prithiviraj Pallavi L Nadig Aravind Sekar Amit Rawat Source Type: research
Food Insecurity in the Elective Enhanced Recovery After Surgery Colorectal Surgical Population: Prevalence and Implications for Surgical Outcomes
DISCUSSION: Food insecurity was found to occur in patients that lived in communities deemed both affluent and distressed. These patients had longer hospital stays and higher mortality. A food insecurity questionnaire can easily identify patients at risk. Further investigations to mitigate these complications are warranted.PMID:37703552 | DOI:10.1177/00031348231198122
Source: The American Surgeon - September 13, 2023 Category: Surgery Authors: Michael Tolkacz Danielle Reilly Diane M Studzinski Rose E Callahan Alexander DeMare Samer Kawak Matthew Ziegler Source Type: research
Outcomes of Injured Patients Before and After the Institution of a Third-Tier Activation at a Level 1 Trauma Center
DISCUSSION: Implementation of the gamma alert was associated with an improvement in ED dwell times, fewer unplanned admissions to the ICU, decreased readmissions, and a reduction in other in-hospital events. We believe that this reflects improved triage of patients to the ICU and more effective care of trauma patients.PMID:37703078 | DOI:10.1177/00031348231200670
Source: The American Surgeon - September 13, 2023 Category: Surgery Authors: Andrew M Young Brian R Young Steven D Young Alexander Brundage Prajeeth Koyada Christopher Cramer Jeffrey S Young Source Type: research
Clinics dedicated to transition preparation for adolescents and young adults with chronic conditions: Factors influencing their use
Arch Pediatr. 2023 Sep 11:S0929-693X(23)00144-6. doi: 10.1016/j.arcped.2023.08.004. Online ahead of print.ABSTRACTTo pool resources and reduce inequalities in access to transition preparation for patients, transition clinics were created in France. They are places in hospitals, independent of the usual care departments, offering multiple resources and services for adolescents and their parents. Of the 24 physicians from care departments who were surveyed, half of them do not use transition clinics. The implementation of transition clinics in hospitals did not lead to their adoption by the care departments that needed the m...
Source: Archives de Pediatrie - September 13, 2023 Category: Pediatrics Authors: Enora Le Roux Aur élie Bourmaud Paul Jacquin Nizar Mahlaoui Aur élien Guffroy Alexandre Belot M élanie Romier Jane Sattoe AnneLoes Van Staa Corinne Alberti H élène Mellerio Agn ès Dumas Source Type: research
Linkage of blood cell division cycle 42 with T helper cells, and their correlation with anxiety, depression, and cognitive impairment in stroke patients
This study aimed to assess the correlation between blood CDC42 and Th cells, and their association with mental issues in stroke patients. Peripheral blood samples were obtained from 264 stroke patients and 50 controls. Then, serum CDC42 was measured by enzyme-linked immunosorbent assay, and Th1, Th2, and Th17 cells were detected by flow cytometry. Hospital Anxiety and Depression Scale (HADS) and Mini Mental State Examination (MMSE) were applied to patients. CDC42 was decreased (P<0.001), Th1 (P=0.013) and Th17 (P<0.001) cells were elevated, while Th2 cells (P=0.108) showed no difference in stroke patients compared to...
Source: Cell Research - September 13, 2023 Category: Cytology Authors: Haifeng Ma Qing Chang Jujuan Jia Yaoyuan Zhang Gang Wang Yuanyuan Li Source Type: research
A retrospective study on newborn screening for metabolic disorders
Bioinformation. 2022 Dec 31;18(12):1122-1125. doi: 10.6026/973206300181122. eCollection 2022.ABSTRACTThe process of testing newborn infants for hormonal, genetic, metabolic, and other disorders is known as newborn screening (NSB). Newborn screening is essential for detecting, diagnosing, and treating disorders that could save serious consequences for a newborn's health. Congenital Hypothyroidism (CH), Cystic Fibrosis (CF), Glucose-6-phosphate dehydrogenase (G6PD) deficiency, and Profound Biotinidase deficiency (BD) are common disorders in India. A retrospective analysis of the results of NBS by Cord blood spots was perform...
Source: Bioinformation - September 13, 2023 Category: Bioinformatics Authors: Karam Chandrajit Singh Prabhkiran Dhillon Thushara Thulaseedharan Source Type: research
Effectiveness of cefmetazole versus meropenem for invasive urinary tract infections caused by extended-spectrum β-lactamase-producing < em > Escherichia coli < /em >
Antimicrob Agents Chemother. 2023 Sep 13:e0051023. doi: 10.1128/aac.00510-23. Online ahead of print.ABSTRACTCefmetazole is active against extended-spectrum β-lactamase-producing Escherichia coli (ESBLEC) and is a potential candidate for carbapenem-sparing therapy. This multicenter, observational study included patients hospitalized for invasive urinary tract infection due to ESBLEC between March 2020 and November 2021 at 10 facilities in Japan, for whom either cefmetazole or meropenem was initiated as a definitive therapy within 96 h of culture collection and continued for at least 3 d. Outcomes included clinical and micr...
Source: Antimicrobial Agents and Chemotherapy - September 13, 2023 Category: Microbiology Authors: Kayoko Hayakawa Yasufumi Matsumura Kohei Uemura Shinya Tsuzuki Aki Sakurai Ryutaro Tanizaki Koh Shinohara Takehiro Hashimoto Ryota Hase Takashi Matono Hideaki Kato Momoko Mawatari Hiroshi Hara Yukihiro Hamada Sho Saito Norio Ohmagari Yohei Doi Source Type: research
Oxidative stress in breast cancer after chemotherapy
Bioinformation. 2022 Dec 31;18(12):1141-1145. doi: 10.6026/973206300181141. eCollection 2022.ABSTRACTIt is of interest to evaluate the influence of breast cancer on oxidative stress, liver function tests, renal biomarkers, action of doxorubicin, cyclophosphamide and paclitaxel (AC-T) in the treatment and mechanism over altering the measured markers in breast cancer. Sixty histopathological confirmed cases of female patients suffering with breast carcinoma from the Department of Oncology at Omega Cancer Hospital, Visakhapatnam were included in the study. The investigation was performed in 3 groups: a control group containin...
Source: Bioinformation - September 13, 2023 Category: Bioinformatics Authors: Tejaswi Pullakanam Sri Phani Murugan Mannangatti Ramakrishna Nekkala Venkata Madhavi Bellala Ravi Shankar Bellala Vijayalakshmi Payala Source Type: research
Outcomes of minimally invasive versus conventional sternotomy for redo mitral valve surgery according to Mitral Valve Academic Research Consortium: A systematic review and meta-analysis
This study aims to evaluate the outcomes of both procedures according to the Mitral Valve Academic Research Consortium (MVARC). This systematic review and meta-analysis were performed in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). Literature searching was performed in several databases including PubMed, EBSCOhost, Scopus, and Proquest up to 28 February 2022. Meta-analysis using proportions or means was applied. A total of 13 retrospective cohort articles were included in this study. The incidence of in-hospital mortality (3% vs 9.2%, OR = 0.35; 95% CI: 0.21-0.58; P ≤ 0.000...
Source: Asian Journal of Surgery - September 13, 2023 Category: Surgery Authors: Dudy Arman Hanafy Stefanie Melisa Galih Asa Andrianto Widya Trianita Suwatri None Sugisman Source Type: research
