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Vaccination: Cancer Vaccines

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Total 8118 results found since Jan 2013.

Vaccination Coverage Among Adolescents Aged 13-17 Years - National Immunization Survey-Teen, United States, 2022
MMWR Morb Mortal Wkly Rep. 2023 Aug 25;72(34):912-919. doi: 10.15585/mmwr.mm7234a3.ABSTRACTThree vaccines are routinely recommended for adolescents to prevent pertussis, meningococcal disease, and cancers caused by human papillomavirus (HPV). CDC analyzed data from the 2022 National Immunization Survey-Teen for 16,043 adolescents aged 13-17 years to assess vaccination coverage. Birth cohort analyses were conducted to assess trends in vaccination coverage by age 13 years (i.e., before the 13th birthday) and by age 14 years (i.e., before the 14th birthday) among adolescents who were due for routine vaccination before and dur...
Source: MMWR Morb Mortal Wkl... - August 24, 2023 Category: Epidemiology Authors: Cassandra Pingali David Yankey Laurie D Elam-Evans Lauri E Markowitz Madeleine R Valier Benjamin Fredua Samuel J Crowe Carla L DeSisto Shannon Stokley James A Singleton Source Type: research

Research progress of nanovaccine in anti-tumor immunotherapy
Tumor vaccines aim to activate dormant or unresponsive tumor-specific T lymphocytes by using tumor-specific or tumor-associated antigens, thus enhancing the body’s natural defense against cancer. However, the effectiveness of tumor vaccines is limited by the presence of tumor heterogeneity, low immunogenicity, and immune evasion mechanisms. Fortunately, multifunctional nanoparticles offer a unique chance to address these issues. With the advantages of their small size, high stability, efficient drug delivery, and controlled surface chemistry, nanomaterials can precisely target tumor sites, improve the delivery of tumor a...
Source: Frontiers in Oncology - August 24, 2023 Category: Cancer & Oncology Source Type: research

Sensors, Vol. 23, Pages 7380: Electrochemical DNA Biosensors with Dual-Signal Amplification Strategy for Highly Sensitive HPV 16 Detection
Jie Du Cervical cancer is an important topic in the study of global health issues, ranking fourth among women’s cancer cases in the world. It is one of the nine major cancers that China is focusing on preventing and treating, and it is the only cancer that can be prevented through vaccination. Systematic and effective screening for human papilloma (HPV) infection, which is closely linked to the development of cervical cancer, can reduce cervical cancer incidence and mortality. In this paper, an electrochemical sensor was designed to detect HPV 16 using dual-signal amplification. An APTES-modified glass...
Source: Sensors - August 24, 2023 Category: Biotechnology Authors: Yuxing Yang Yazhen Liao Yang Qing Haiyu Li Jie Du Tags: Article Source Type: research

Breast cancer vaccines; A comprehensive and updated review
Pathol Res Pract. 2023 Aug 4;249:154735. doi: 10.1016/j.prp.2023.154735. Online ahead of print.ABSTRACTAccording to the International Agency for Research on Cancer, breast cancer is more common than lung cancer globally. By 2040, mortality from breast cancer will rise by 50% and 40%, respectively. Despite advances in chemotherapy, endocrine therapy, and HER2-targeted therapy, breast cancer metastases and recurrences remain challenging to treat. Cancer vaccines are an effective treatment option because they stimulate a long-lasting immune response that will eliminate tumor cells. In studies on the breast cancer vaccine, no ...
Source: Pathology, Research and Practice - August 23, 2023 Category: Pathology Authors: Sulieman Ibraheem Shelash Al-Hawary Ebraheem Abdu Musad Saleh Nodirjon Akhmetovich Mamajanov Nataliya S Gilmanova Hashem O Alsaab Adel Alghamdi Shakeel Ahmed Ansari Ahmed Hussien Radie Alawady Ali Hashiem Alsaalamy Ahmed Jaber Ibrahim Source Type: research

The Cooperation of IL-29 and PLGA Nanoparticles Improves the Protective Immunity of the gD-1 DNA Vaccine Against Herpes Simplex Virus Type 1 in Mice
In this study, the pIL-29 encapsulated in PLGA nanoparticles (nanoIL-29) and the pgD1 encapsulated in PLGA nanoparticles (nanoVac) were simultaneously applied to boost immunologic responses against HSV-1. We generated spherical nanoparticles with encapsulation efficiency of 75 ± 5% and sustained the release of plasmids from them. Then, Balb/c mice were subcutaneously immunized twice with nanoVac+nanoIL-29, Vac+IL-29, nanoVac, Vac, nanoIL-29, and/or IL-29 in addition to negative and positive control groups. Cellular immunity was evaluated via lymphocyte proliferation assay, cytotoxicity test, and IFN-γ, IL-4, and IL-2 mea...
Source: Cancer Control - August 23, 2023 Category: Cancer & Oncology Authors: Parisa Amir Kalvanagh Hesam Karimi Hoorieh Soleimanjahi Massoumeh Ebtekar Parviz Kokhaei Zahra Matloubi Roghieh Rahimi Nazanin Atieh Kazemi-Sefat Hajar Rajaei Source Type: research

Breast cancer vaccines; A comprehensive and updated review
Pathol Res Pract. 2023 Aug 4;249:154735. doi: 10.1016/j.prp.2023.154735. Online ahead of print.ABSTRACTAccording to the International Agency for Research on Cancer, breast cancer is more common than lung cancer globally. By 2040, mortality from breast cancer will rise by 50% and 40%, respectively. Despite advances in chemotherapy, endocrine therapy, and HER2-targeted therapy, breast cancer metastases and recurrences remain challenging to treat. Cancer vaccines are an effective treatment option because they stimulate a long-lasting immune response that will eliminate tumor cells. In studies on the breast cancer vaccine, no ...
Source: Pathology, Research and Practice - August 23, 2023 Category: Pathology Authors: Sulieman Ibraheem Shelash Al-Hawary Ebraheem Abdu Musad Saleh Nodirjon Akhmetovich Mamajanov Nataliya S Gilmanova Hashem O Alsaab Adel Alghamdi Shakeel Ahmed Ansari Ahmed Hussien Radie Alawady Ali Hashiem Alsaalamy Ahmed Jaber Ibrahim Source Type: research

Prior cycles of anti-CD20 antibodies affect antibody responses after repeated SARS-CoV-2 mRNA vaccination
CONCLUSIONThese results demonstrate that serial vaccination strategies can be effective for a subset of B cell-depleted patients.FUNDINGThe NIH (R25 NS079193, P01 AI073748, U24 AI11867, R01 AI22220, UM 1HG009390, P01 AI039671, P50 CA121974, R01 CA227473, U01CA260507, 75N93019C00065, K24 AG042489), NIH HIPC Consortium (U19 AI089992), the National Multiple Sclerosis Society (CA 1061-A-18, RG-1802-30153), the Nancy Taylor Foundation for Chronic Diseases, Erase MS, and the Claude D. Pepper Older Americans Independence Center at Yale (P30 AG21342).PMID:37606046 | DOI:10.1172/jci.insight.168102
Source: Cancer Control - August 22, 2023 Category: Cancer & Oncology Authors: Hiromitsu Asashima Dongjoo Kim Kaicheng Wang Nikhil Lele Nicholas C Buitrago-Pocasangre Rachel Lutz Isabella Cruz Khadir Raddassi William E Ruff Michael K Racke JoDell E Wilson Tara S Givens Alba Grifoni Daniela Weiskopf Alessandro Sette Steven H Kleinste Source Type: research

Outer membrane vesicle-based intranasal vaccines
Curr Opin Immunol. 2023 Aug 18;84:102376. doi: 10.1016/j.coi.2023.102376. Online ahead of print.ABSTRACTDelivery of vaccines via the mucosal route is regarded as the most effective mode of immunization to counteract infectious diseases that enter via mucosal tissues, including oral, nasal, pulmonary, intestinal, and urogenital surfaces. Mucosal vaccines not only induce local immune effector elements, such as secretory Immunoglobulin A (IgA) reaching the luminal site of the mucosa, but also systemic immunity. Moreover, mucosal vaccines may trigger immunity in distant mucosal tissues because of the homing of primed antigen-s...
Source: Current Opinion in Immunology - August 20, 2023 Category: Allergy & Immunology Authors: Peter Van der Ley Virgil Ejc Schijns Source Type: research