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Vaccination: Cancer Vaccines
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Total 8118 results found since Jan 2013.
Viral nanoparticles: Current advances in design and development
Biochimie. 2023 Aug 10:S0300-9084(23)00197-9. doi: 10.1016/j.biochi.2023.08.006. Online ahead of print.ABSTRACTViral nanoparticles (VNPs) are self-assembling, adaptable delivery systems for vaccines and other therapeutic agents used in a variety of biomedical applications. The potential of viruses to invade and infect various hosts and cells renders them suitable as potential nanocarriers, possessing distinct functional characteristics, immunogenic properties, and improved biocompatibility and biodegradability. VPNs are frequently produced through precise genetic or chemical engineering, which involves adding diverse seque...
Source: Biochimie - August 12, 2023 Category: Biochemistry Authors: Siva Santhiya Arul Brinda Balakrishnan Savithri S Handanahal Sangita Venkataraman Source Type: research
Recent Advances in Messenger Ribonucleic Acid (mRNA) Vaccines and Their Delivery Systems: A Review
Clin Pharmacol. 2023 Aug 3;15:77-98. doi: 10.2147/CPAA.S418314. eCollection 2023.ABSTRACTMessenger ribonucleic acid (mRNA) was found as the intermediary that transfers genetic information from DNA to ribosomes for protein synthesis in 1961. The emergency use authorization of the two covid-19 mRNA vaccines, BNT162b2 and mRNA-1273, is a significant achievement in the history of vaccine development. Because they are generated in a cell-free environment using the in vitro transcription (IVT) process, mRNA vaccines are risk-free. Moreover, chemical modifications to the mRNA molecule, such as cap structures and changed nucleosid...
Source: Clinical Pharmacology: Advances and Applications - August 9, 2023 Category: Allergy & Immunology Authors: Wubetu Yihunie Getinet Nibret Yibeltal Aschale Source Type: research
Predictors of Colonoscopy Use Among Asian Indians in New York City, 2003 to 2016
CONCLUSIONS: Among Asian Indians living in New York City, several demographic, socioeconomic, and health-related characteristics predict colonoscopy use. These findings highlight the importance of examining determinants of colonoscopy uptake in this understudied population to inform future public health interventions.PMID:37556383 | DOI:10.1097/MCG.0000000000001900
Source: Clinical Colorectal Cancer - August 9, 2023 Category: Cancer & Oncology Authors: Neha Nagpal Taylor M McCready Yuhe Xia Kevin Lin Matthew Glenn Sandy Ng Chau Trinh-Shevrin Andrea B Troxel Simona C Kwon Peter S Liang Source Type: research
Recent Advances in Messenger Ribonucleic Acid (mRNA) Vaccines and Their Delivery Systems: A Review
Clin Pharmacol. 2023 Aug 3;15:77-98. doi: 10.2147/CPAA.S418314. eCollection 2023.ABSTRACTMessenger ribonucleic acid (mRNA) was found as the intermediary that transfers genetic information from DNA to ribosomes for protein synthesis in 1961. The emergency use authorization of the two covid-19 mRNA vaccines, BNT162b2 and mRNA-1273, is a significant achievement in the history of vaccine development. Because they are generated in a cell-free environment using the in vitro transcription (IVT) process, mRNA vaccines are risk-free. Moreover, chemical modifications to the mRNA molecule, such as cap structures and changed nucleosid...
Source: Clinical Pharmacology: Advances and Applications - August 9, 2023 Category: Allergy & Immunology Authors: Wubetu Yihunie Getinet Nibret Yibeltal Aschale Source Type: research
Breast and gynecologic cancers as a Brazilian health priority
CONCLUSION: Analyzed together, breast and gynecologic cancers correspond to the leading cause of cancer in Brazil. A heterogeneous group, female cancer includes diseases with a high primary and secondary prevention potential. The organization of a female cancer program in Brazil prioritizing primary and secondary prevention strategies, such as adequate mammography screening and human papillomavirus vaccination coverage, could significantly improve female cancer control in the country.PMID:37556639 | DOI:10.1590/1806-9282.2023S120
Source: Cancer Control - August 9, 2023 Category: Cancer & Oncology Authors: Ang élica Nogueira-Rodrigues Daniela Dornelles Rosa Daniele Assad Suzuki Eduardo Paulino Luciana Castro Garcia Landeiro Mariana Scaranti Marisa Riscalla Madi Paulo Marcelo Hoff Source Type: research
Structural Framework for Analysis of CD4+ T-Cell Epitope Dominance in Viral Fusion Proteins
Biochemistry. 2023 Aug 9. doi: 10.1021/acs.biochem.3c00335. Online ahead of print.ABSTRACTAntigen conformation shapes CD4+ T-cell specificity through mechanisms of antigen processing, and the consequences for immunity may rival those from conformational effects on antibody specificity. CD4+ T cells initiate and control immunity to pathogens and cancer and are at least partly responsible for immunopathology associated with infection, autoimmunity, and allergy. The primary trigger for CD4+ T-cell maturation is the presentation of an epitope peptide in the MHC class II antigen-presenting protein (MHCII), most commonly on an a...
Source: Cancer Control - August 9, 2023 Category: Cancer & Oncology Authors: Samuel J Landry Ramgopal R Mettu Jay K Kolls Judith H Aberle Elizabeth Norton Kevin Zwezdaryk James Robinson Source Type: research
Recent Advances in Messenger Ribonucleic Acid (mRNA) Vaccines and Their Delivery Systems: A Review
Clin Pharmacol. 2023 Aug 3;15:77-98. doi: 10.2147/CPAA.S418314. eCollection 2023.ABSTRACTMessenger ribonucleic acid (mRNA) was found as the intermediary that transfers genetic information from DNA to ribosomes for protein synthesis in 1961. The emergency use authorization of the two covid-19 mRNA vaccines, BNT162b2 and mRNA-1273, is a significant achievement in the history of vaccine development. Because they are generated in a cell-free environment using the in vitro transcription (IVT) process, mRNA vaccines are risk-free. Moreover, chemical modifications to the mRNA molecule, such as cap structures and changed nucleosid...
Source: Clinical Pharmacology: Advances and Applications - August 9, 2023 Category: Allergy & Immunology Authors: Wubetu Yihunie Getinet Nibret Yibeltal Aschale Source Type: research
Predictors of Colonoscopy Use Among Asian Indians in New York City, 2003 to 2016
CONCLUSIONS: Among Asian Indians living in New York City, several demographic, socioeconomic, and health-related characteristics predict colonoscopy use. These findings highlight the importance of examining determinants of colonoscopy uptake in this understudied population to inform future public health interventions.PMID:37556383 | DOI:10.1097/MCG.0000000000001900
Source: Clinical Colorectal Cancer - August 9, 2023 Category: Cancer & Oncology Authors: Neha Nagpal Taylor M McCready Yuhe Xia Kevin Lin Matthew Glenn Sandy Ng Chau Trinh-Shevrin Andrea B Troxel Simona C Kwon Peter S Liang Source Type: research
Recent Advances in Messenger Ribonucleic Acid (mRNA) Vaccines and Their Delivery Systems: A Review
Clin Pharmacol. 2023 Aug 3;15:77-98. doi: 10.2147/CPAA.S418314. eCollection 2023.ABSTRACTMessenger ribonucleic acid (mRNA) was found as the intermediary that transfers genetic information from DNA to ribosomes for protein synthesis in 1961. The emergency use authorization of the two covid-19 mRNA vaccines, BNT162b2 and mRNA-1273, is a significant achievement in the history of vaccine development. Because they are generated in a cell-free environment using the in vitro transcription (IVT) process, mRNA vaccines are risk-free. Moreover, chemical modifications to the mRNA molecule, such as cap structures and changed nucleosid...
Source: Clinical Pharmacology: Advances and Applications - August 9, 2023 Category: Allergy & Immunology Authors: Wubetu Yihunie Getinet Nibret Yibeltal Aschale Source Type: research
