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Total 4677907 results found since Jan 2013.

Effects of MLC601 on Early Vascular Events in Patients After Stroke: The CHIMES Study Brief Reports
Conclusions— Treatment with MLC601 was associated with reduced early vascular events among subjects in the CHIMES study. The mechanisms for this effect require further study. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00554723.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Chen, C. L. H., Venketasubramanian, N., Lee, C. F., Wong, K. S. L., Bousser, M.-G., for The CHIMES Study Investigators, CHIMES Study Investigators, Philippines, Navarro, Gan, Lao, Baroque, Lokin, Hiyadan, Sarfati, Fangonillo, Ambasing, Chua, San Jose, Adv Tags: Secondary prevention, Acute Cerebral Infarction, Other Stroke Treatment - Medical, Other Vascular biology Brief Reports Source Type: research

Impact of Emergency Medical Services Stroke Routing Protocols on Primary Stroke Center Certification in California Brief Reports
Conclusions— Implementation of EMS routing policies may be an important factor driving PSC certification. National adoption of stroke routing policies may lead to more PSCs, positively impacting patient care.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Schuberg, S., Song, S., Saver, J. L., Mack, W. J., Cen, S. Y., Sanossian, N. Tags: Health policy and outcome research, Emergency treatment of Stroke Brief Reports Source Type: research

The Prognostic Effect of Cigarette Smoking on Stroke Severity, Disability, Length of Stay in Hospital, and Mortality in a Cohort with Cerebrovascular Disease
Conclusions: Our results provide empirical evidence regarding the prognostic influence of cigarette smoking on stroke severity, disability, and LOS in hospital and mortality, but the magnitude of the effect varied by stroke type.
Source: Journal of Stroke and Cerebrovascular Diseases - June 10, 2013 Category: Neurology Authors: Rojiemiahd K. Edjoc, Robert D. Reid, Mukul Sharma, Jiming Fang, Registry of the Canadian Stroke Network Tags: Original Articles Source Type: research

Global stroke statistics
In many countries, stroke is a lower priority than other diseases despite its public health impact. One issue is a lack of readily accessible comparative data to help make the case for the development of national stroke strategies. To assist in this process, we need to have a common repository of the latest published information on the impact of stroke worldwide. We aim to provide a repository of the most current incidence and mortality data on stroke available by country and illustrate the gaps in these data. We plan to update this repository annually and expand the scope to address other aspects of the burden of stroke. ...
Source: International Journal of Stroke - December 19, 2013 Category: Neurology Authors: Amanda G. Thrift, Dominique A. Cadilhac, Tharshanah Thayabaranathan, George Howard, Virginia J. Howard, Peter M. Rothwell, Geoffrey A. Donnan Tags: Global stroke statistics Source Type: research

Design and Validation of a Prehospital Stroke Scale to Predict Large Arterial Occlusion: The Rapid Arterial Occlusion Evaluation Scale Clinical Sciences
Conclusions— The RACE scale is a simple tool that can accurately assess stroke severity and identify patients with acute stroke with large artery occlusion at prehospital setting by medical emergency technicians.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Perez de la Ossa, N., Carrera, D., Gorchs, M., Querol, M., Millan, M., Gomis, M., Dorado, L., Lopez-Cancio, E., Hernandez-Perez, M., Chicharro, V., Escalada, X., Jimenez, X., Davalos, A. Tags: Cerebrovascular disease/stroke, Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research

Outcome of Standard and High-Risk Patients With Acute Anterior Circulation Stroke After Stent Retriever Thrombectomy Clinical Sciences
Conclusions— Patients <80 years of age, without extensive pretreatment ischemic signs, and baseline National Institutes of Health Stroke Scale score ≤30 had high rates of favorable outcome and low periprocedural complication rates after Solitaire thrombectomy. Successful reperfusion was also common in patients not fulfilling standard inclusion criteria, but worse clinical outcomes warrant further research with a special focus on optimal patient selection.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Gratz, P. P., Jung, S., Schroth, G., Gralla, J., Mordasini, P., Hsieh, K., Heldner, M. R., Mattle, H. P., Mono, M.-L., Fischer, U., Arnold, M., Zubler, C. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Other Stroke Clinical Sciences Source Type: research

Protective Effect of Time Spent Walking on Risk of Stroke in Older Men Clinical Sciences
Conclusions— Time spent walking was associated with reduced risk of onset of stroke in dose–response fashion, independent of walking pace. Walking could form an important part of stroke-prevention strategies in older people.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Jefferis, B. J., Whincup, P. H., Papacosta, O., Wannamethee, S. G. Tags: Behavioral Changes and Stroke, Epidemiology, Coagulation and fibronolysis Clinical Sciences Source Type: research

Quality of Care and Outcomes for In-Hospital Ischemic Stroke: Findings From the National Get With The Guidelines-Stroke Clinical Sciences
Conclusions— Compared with community-onset ischemic stroke, patients with in-hospital stroke experienced more severe strokes, received lower adherence to process-based quality measures, and had worse outcomes. These findings suggest there is an important opportunity for targeted quality improvement efforts for patients with in-hospital stroke.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Cumbler, E., Wald, H., Bhatt, D. L., Cox, M., Xian, Y., Reeves, M., Smith, E. E., Schwamm, L., Fonarow, G. C. Tags: Health policy and outcome research, Emergency treatment of Stroke, Risk Factors for Stroke, Thrombolysis Clinical Sciences Source Type: research

Time to Brain Imaging in Acute Stroke Is Improving: Secondary Analysis of the INSTINCT Trial Brief Reports
Conclusions— Performance on DIT improved similarly in intervention and control hospitals, suggesting that nonintervention factors explain the improvement. Hospital-level factors explain a modest proportion of variation in DIT, but further research is needed to identify the hospital-level factors responsible.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Sauser, K., Burke, J. F., Levine, D. A., Scott, P. A., Meurer, W. J. Tags: Emergency treatment of Stroke Brief Reports Source Type: research

Quality of Acute Ischemic Stroke Care in Thailand: A Prospective Multicenter Countrywide Cohort Study
Conclusions: Limited access to acute ischemic stroke care interventions were observed in many domains especially thrombolysis and stroke unit admission. These findings emphasize an urgent need for strategies to improve standard acute stroke care among developing countries.
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2013 Category: Neurology Authors: Yongchai Nilanont, Samart Nidhinandana, Nijasri C. Suwanwela, Suchat Hanchaiphiboolkul, Taksin Pimpak, Pyatat Tatsanavivat, Gustavo Saposnik, Niphon Poungvarin, Thai Stroke Registry Tags: Original Articles Source Type: research

Regulation of CARD8 Expression by ANRIL and Association of CARD8 Single Nucleotide Polymorphism rs2043211 (p.C10X) With Ischemic Stroke Clinical Sciences
Conclusions— CARD8 is a downstream target gene regulated by ANRIL. Single nucleotide polymorphism rs2043211 in CARD8 is significantly associated with ischemic stroke. ANRIL may increase the risk of ischemic stroke through regulation of the CARD8 pathway.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Bai, Y., Nie, S., Jiang, G., Zhou, Y., Zhou, M., Zhao, Y., Li, S., Wang, F., Lv, Q., Huang, Y., Yang, Q., Li, Q., Li, Y., Xia, Y., Liu, Y., Liu, J., Qian, J., Li, B., Wu, G., Wu, Y., Wang, B., Cheng, X., Yang, Y., Ke, T., Li, H., Ren, X., Ma, X., Liao, Y. Tags: Functional genomics, Genetics of Stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

Transient Global Amnesia and the Risk of Ischemic Stroke Clinical Sciences
Conclusions— Compared with patients diagnosed with migraine or seizure, patients diagnosed with TGA do not seem to face a heightened risk of stroke.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Mangla, A., Navi, B. B., Layton, K., Kamel, H. Tags: Cerebrovascular disease/stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

ABCD3 and ABCD3-I Scores Are Superior to ABCD2 Score in the Prediction of Short- and Long-Term Risks of Stroke After Transient Ischemic Attack Clinical Sciences
Conclusions— The present study demonstrates that ABCD3 and ABCD3-I scores are superior to the ABCD2 score for the prediction of subsequent stroke in patients with TIA. Addition of neuroimaging in the ABCD3 score may enable prediction of long-term stroke risk after TIA.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Kiyohara, T., Kamouchi, M., Kumai, Y., Ninomiya, T., Hata, J., Yoshimura, S., Ago, T., Okada, Y., Kitazono, T., for the FSR investigators, Fukuoka Stroke Registry Investigators, The participating hospitals in the Fukuoka Stroke Registry were the following Tags: Acute Cerebral Infarction Clinical Sciences Source Type: research

Prospective Study of Anxiety and Incident Stroke Clinical Sciences
Conclusions— Higher anxiety symptom levels were associated prospectively with increased risk for incident stroke independent of other risk factors, including depression. Anxiety is a modifiable experience that is highly prevalent among the general population. Its assessment and treatment may contribute to developing more effective preventive and intervention strategies for improving overall cardiovascular health.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Lambiase, M. J., Kubzansky, L. D., Thurston, R. C. Tags: Behavioral/psychosocial - stroke Clinical Sciences Source Type: research

Extensive Leukoaraiosis Is Associated With High Early Risk of Recurrence After Ischemic Stroke Clinical Sciences
Conclusions— The extent of leukoaraiosis independently predicts 90-day recurrent stroke risk after ischemic stroke. This suggests that leukoaraiosis may be used for risk stratification in ischemic stroke.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Kim, G.-M., Park, K.-Y., Avery, R., Helenius, J., Rost, N., Rosand, J., Rosen, B., Ay, H. Tags: CT and MRI, Acute Cerebral Infarction, Risk Factors for Stroke Clinical Sciences Source Type: research