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Monte Carlo dosimetry of a novel Yttrium-90 disc source for episcleral brachytherapy
CONCLUSION: Monte Carlo simulations were successfully performed to confirm the measured PDD curve of the novel Y-90 disc source. This simulation work laid a solid foundation for characterizing the full dosimetry parameters of this source for episcleral brachytherapy applications.PMID:37708092 | DOI:10.1002/acm2.14140
Source: Journal of Applied Clinical Medical Physics - September 14, 2023 Category: Physics Authors: Xiangyun Chang Lyu Huang Jian Liu Yijian Cao Jenghwa Chang Source Type: research

The role of multidisciplinary team and stepwise pelvic devascularization to minimize blood loss during total pelvic exenteration for patients refusing blood transfusion
We describe the case of a female Jehovah's Witness patient in her 60s undergoing pelvic exenteration, focusing on the preoperative, intraoperative, and postoperative measures that allowed an uncomplicated surgery without blood transfusion. Blood transfusions are common in the surgical management of gynecology oncology patients, up to 93% of patients undergoing pelvic exenteration may require blood products. However, increasingly more patients are cautious in receiving blood products, either for fear of potential risks or for religious believes. It is therefore vital to optimize the management of these patients in order to ...
Source: Clinical Case Reports - September 14, 2023 Category: General Medicine Authors: Valentina Le  Thanh, Richard Bell, Nicholas Symons, Hooman Soleymani Majd Tags: CASE REPORT Source Type: research

Cancers, Vol. 15, Pages 4549: Salvage High-Dose-Rate Interventional Radiotherapy (Brachytherapy) Combined with Surgery for Regionally Relapsed Head and Neck Cancers
Conclusions: Salvage HDR-IRT combined with surgery offers a second-line curative treatment option for regionally relapsed head and neck cancers with acceptable outcomes and toxicities.
Source: Cancers - September 14, 2023 Category: Cancer & Oncology Authors: Tamer Soror Justina Paul Corinna Melchert Christian Idel Dirk Rades Karl-Ludwig Bruchhage Gy örgy Kovács Anke Leichtle Tags: Article Source Type: research

Uncertainty in magnetic resonance imaging-based prostate postimplant dosimetry: Results of a 10-person human observer study, and comparisons with automatic postimplant dosimetry
Uncertainties in postimplant quality assessment (QA) for low-dose-rate prostate brachytherapy (LDRPBT) are introduced at two steps: seed localization and contouring. We quantified how interobserver variability (IoV) introduced in both steps impacts dose-volume-histogram (DVH) parameters for MRI-based LDRPBT, and compared it with automatically derived DVH parameters.
Source: Brachytherapy - September 14, 2023 Category: Cancer & Oncology Authors: Jeremiah W. Sanders, Chad Tang, Rajat J. Kudchadker, Aradhana M. Venkatesan, Henry Mok, Alexander N. Hanania, Howard D. Thames, Teresa L. Bruno, Christine Starks, Edwin Santiago, Mandy Cunningham, Steven J. Frank Source Type: research

Improved safety and quality in intravascular brachytherapy: A multi-institutional study using failure modes and effects analysis
Highlight safety considerations in intravascular brachytherapy (IVBT) programs, provide relevant quality assurance (QA) and safety measures, and establish their effectiveness.
Source: Brachytherapy - September 14, 2023 Category: Cancer & Oncology Authors: Evan D.H. Gates, Kent Wallner, Jasleen Tiwana, Eric Ford, Mark Phillips, Lan Lu, Vishruta Dumane, Ren-Dih Sheu, Minsun Kim Source Type: research

Reirradiation with advanced brachytherapy techniques in recurrent GYN cancers
To evaluate clinical outcomes of recurrent gynaecological cancers treated with reirradiation (reRT) using advanced brachytherapy (BT) technique.
Source: Brachytherapy - September 14, 2023 Category: Cancer & Oncology Authors: Umesh Mahantshetty, Sheetal R. Kashid, Gargee Mulye, Lavanya Gurram, Reena Engineer, Supriya Chopra, Jaya Ghosh, Seema Gulia, Sudeep Gupta, Yogesh Ghadi, Dheera A ., Satish Kohle, Sudarshan Kadam, Santosh Menon, Kedar Deodhar, Amita Maheswari, Shylasree Source Type: research

Benchmarking ChatGPT-4 on a radiation oncology in-training exam and Red Journal Gray Zone cases: potentials and challenges for ai-assisted medical education and decision making in radiation oncology
ConclusionBoth evaluations demonstrate the potential of ChatGPT-4 in medical education for the general public and cancer patients, as well as the potential to aid clinical decision-making, while acknowledging its limitations in certain domains. Owing to the risk of hallucinations, it is essential to verify the content generated by models such as ChatGPT for accuracy.
Source: Frontiers in Oncology - September 14, 2023 Category: Cancer & Oncology Source Type: research

Are 7.5gy ×2 fractions more efficient than 6gy×3 in exclusive postoperative endometrial cancer brachytherapy? a clinical and dosimetrical analysis
CONCLUSION: Considering the lack of vaginal relapses and similar LVT over time, 7.5Gy×2fractions seem more efficient in terms of patient comfort, workload, and cost. This is the first study using dosimetry parameters to compare effectivity of schedules. Larger series are needed to confirm the present results.PMID:37699447 | DOI:10.1016/j.radonc.2023.109909
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 12, 2023 Category: Radiology Authors: Faegheh Noorian Rosa Abellana Yaowen Zhang Antonio Herreros Clara Baltrons Vallentina Lancellota Luca Tagliaferri Sebastia Sabater Aureli Torne Angeles Rovirosa Source Type: research

Are 7.5gy ×2 fractions more efficient than 6gy×3 in exclusive postoperative endometrial cancer brachytherapy? a clinical and dosimetrical analysis
CONCLUSION: Considering the lack of vaginal relapses and similar LVT over time, 7.5Gy×2fractions seem more efficient in terms of patient comfort, workload, and cost. This is the first study using dosimetry parameters to compare effectivity of schedules. Larger series are needed to confirm the present results.PMID:37699447 | DOI:10.1016/j.radonc.2023.109909
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 12, 2023 Category: Radiology Authors: Faegheh Noorian Rosa Abellana Yaowen Zhang Antonio Herreros Clara Baltrons Vallentina Lancellota Luca Tagliaferri Sebastia Sabater Aureli Torne Angeles Rovirosa Source Type: research

Are 7.5gy ×2 fractions more efficient than 6gy×3 in exclusive postoperative endometrial cancer brachytherapy? a clinical and dosimetrical analysis
CONCLUSION: Considering the lack of vaginal relapses and similar LVT over time, 7.5Gy×2fractions seem more efficient in terms of patient comfort, workload, and cost. This is the first study using dosimetry parameters to compare effectivity of schedules. Larger series are needed to confirm the present results.PMID:37699447 | DOI:10.1016/j.radonc.2023.109909
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 12, 2023 Category: Radiology Authors: Faegheh Noorian Rosa Abellana Yaowen Zhang Antonio Herreros Clara Baltrons Vallentina Lancellota Luca Tagliaferri Sebastia Sabater Aureli Torne Angeles Rovirosa Source Type: research

Clinical outcomes of radioactive seed brachytherapy and microwave ablation in inoperable stage I non-small cell lung cancer
This study assessed the efficacy and safety of radioactive iodine-125 seed ablation brachytherapy (RSABT) in comparison to microwave ablation therapy (MWAT) for treating inoperable stage I non-small cell lung cancer (NSCLC). We conducted a retrospective analysis of data from stage I NSCLC patients who underwent CT-guided RSABT or MWAT. The primary outcomes measured were progression-free survival (PFS), overall survival (OS), and the occurrence of adverse events. Of the patients included in the study, 71 underwent RSABT and 105 received MWAT. The median follow-up time for these groups was 47.4 months and 60 months, respecti...
Source: Cell Research - September 11, 2023 Category: Cytology Authors: Zhe Ji Yang Ni Chuang He Bin Huo Shifeng Liu Yanli Ma Yuqing Song Miaomiao Hu Kaixian Zhang Zhe Wang Xinxin Zhao Hongmei Han Yufeng Wang Ruoyu Wang Shude Chai Xiaokun Hu Xuequan Huang Xin Ye Junjie Wang Source Type: research

The American Brachytherapy Society and Indian Brachytherapy Society consensus statement for the establishment of high-dose-rate brachytherapy programs for gynecological malignancies in low- and middle-income countries
The global cervical cancer burden is disproportionately high in low- and middle-income countries (LMICs), and outcomes can be governed by the accessibility of appropriate screening and treatment. High-dose-rate (HDR) brachytherapy plays a central role in cervical cancer treatment, improving local control and overall survival. The American Brachytherapy Society (ABS) and Indian Brachytherapy Society (IBS) collaborated to provide this succinct consensus statement guiding the establishment of brachytherapy programs for gynecological malignancies in resource-limited settings.
Source: Brachytherapy - September 11, 2023 Category: Cancer & Oncology Authors: Surbhi Grover, Katie E. Lichter, Anna Likhacheva, Joanne W. Jang, Matthew S. Ning, Tyler P. Robin, William Small, Rajat J. Kudchadker, Jamema Swamidas, Supriya Chopra, Bhavana Rai, Sunil Dutt Sharma, Daya N. Sharma, Thayalan Kuppusamy, Ruijie Yang, Daniel Source Type: research

Are 7.5gy ×2 fractions more efficient than 6gy×3 in exclusive postoperative endometrial cancer brachytherapy? a clinical and dosimetrical analysis
Endometrial cancer (EC) is the second most common gynecological malignancy worldwide and the first in developed countries, with a 5-year prevalence of 34.7%. In Spain,it is the third most common cancer in womenfollowing breast and colorectal cancer [1 –4].
Source: Radiotherapy and Oncology - September 10, 2023 Category: Radiology Authors: Faegheh Noorian, Rosa Abellana, Yaowen Zhang, Antonio Herreros, Clara Baltrons, Vallentina Lancellota, Luca Tagliaferri, Sebastia Sabater, Aureli Torne, Angeles Rovirosa Tags: Original Article Source Type: research